Integrate-and-fire
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Integrate-and-fire
Biological neuron models, also known as a spiking neuron models, are mathematical descriptions of the properties of certain cells in the nervous system that generate sharp electrical potentials across their cell membrane, roughly one millisecond in duration, called action potentials or spikes (Fig. 2). Since spikes are transmitted along the axon and synapses from the sending neuron to many other neurons, spiking neurons are considered to be a major information processing unit of the nervous system. Spiking neuron models can be divided into different categories: the most detailed mathematical models are biophysical neuron models (also called Hodgkin-Huxley models) that describe the membrane voltage as a function of the input current and the activation of ion channels. Mathematically simpler are integrate-and-fire models that describe the membrane voltage as a function of the input current and predict the spike times without a description of the biophysical processes that shape ...
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Spike Time Prediction With Generalized Integrate-and-Fire Model
Spike, spikes, or spiking may refer to: Arts, entertainment, and media Books * ''The Spike'' (novel), a novel by Arnaud de Borchgrave * ''The Spike'' (book), a nonfiction book by Damien Broderick * ''The Spike'', a starship in Peter F. Hamilton's ''The Evolutionary Void'' Comics * ''Spike'' (DC Thomson) a British comics anthology published by DC Thomson * ''Spike'' (IDW Publishing), a comic book series featuring the ''Buffy the Vampire Slayer'' character Film and television * ''Spike'' (2008 film), directed by Robert Beaucage * Spike (dog), a dog actor * Spike (TV channel), a former name of the American cable network Paramount Network ** 5Spike, a former localized British version of the American channel ** Spike (Australian TV channel), a localized version of the American channel ** Spike (Dutch TV channel), a localized version of the American channel * "Spike!", a segment of the 2017 Thai TV series '' Project S: The Series'' Music * ''Spike'' (Agata album), 2004 * ''Sp ...
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Leaky Integrate-and-Fire Model Neuron (schematic)
Leakey may refer to: *Leakey, Texas, U.S., a city *Leakey (crater), a lunar impact crater *Leakey (surname) *7958 Leakey, an asteroid *Leakey Independent School District, a public school district based in Leakey, Texas See also *Leak (other) __NOTOC__ A leak is a way for matter to escape a container. Leak may also refer to: Information leaks * News leak, the unsanctioned release of confidential information to news media * Data leak ** Internet leak, a release of confidential informati ...
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Refractory Period (physiology)
Refractoriness is the fundamental property of any object of autowave nature (especially excitable medium) not to respond on stimuli, if the object stays in the specific ''refractory state''. In common sense, refractory period is the characteristic recovery time, a period that is associated with the motion of the image point on the left branch of the isocline \dot = 0 (for more details, see also Reaction–diffusion and Parabolic partial differential equation). In physiology, a refractory period is a period of time during which an organ or cell is incapable of repeating a particular action, or (more precisely) the amount of time it takes for an excitable membrane to be ready for a second stimulus once it returns to its resting state following an excitation. It most commonly refers to electrically excitable muscle cells or neurons. Absolute refractory period corresponds to depolarization and repolarization, whereas relative refractory period corresponds to hyperpolarization ...
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Dirac Delta Function
In mathematics, the Dirac delta distribution ( distribution), also known as the unit impulse, is a generalized function or distribution over the real numbers, whose value is zero everywhere except at zero, and whose integral over the entire real line is equal to one. The current understanding of the unit impulse is as a linear functional that maps every continuous function (e.g., f(x)) to its value at zero of its domain (f(0)), or as the weak limit of a sequence of bump functions (e.g., \delta(x) = \lim_ \frace^), which are zero over most of the real line, with a tall spike at the origin. Bump functions are thus sometimes called "approximate" or "nascent" delta distributions. The delta function was introduced by physicist Paul Dirac as a tool for the normalization of state vectors. It also has uses in probability theory and signal processing. Its validity was disputed until Laurent Schwartz developed the theory of distributions where it is defined as a linear form acting on ...
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Louis Lapicque
Louis Édouard Lapicque (1 August 1866 – 6 December 1952) was a French neuroscientist, socialist activist, antiboulangist, dreyfusard and freemason who was very influential in the early 20th century. One of his main contributions was to propose the integrate-and-fire model of the neuron in a seminal article published in 1907. Today, this model of the neuron is still one of the most popular models in computational neuroscience for both cellular and neural networks studies, as well as in mathematical neuroscience because of its simplicity. A review article was published for the centenary of the original Lapicque's 1907 paper - this review also contains an English translation of the original paper. His wife, Marcelle Lapicque Marcelle de Heredia Lapicque (1873 – 1960) was a French Neurophysiology, neurophysiologist known for her research on nerve impulses (chronaxie) and the effects of poisons, especially strychnine, on chronaxie. She was in charge of the Laboratoire ..., w ...
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Analysis Of Algorithms
In computer science, the analysis of algorithms is the process of finding the computational complexity of algorithms—the amount of time, storage, or other resources needed to execute them. Usually, this involves determining a function that relates the size of an algorithm's input to the number of steps it takes (its time complexity) or the number of storage locations it uses (its space complexity). An algorithm is said to be efficient when this function's values are small, or grow slowly compared to a growth in the size of the input. Different inputs of the same size may cause the algorithm to have different behavior, so best, worst and average case descriptions might all be of practical interest. When not otherwise specified, the function describing the performance of an algorithm is usually an upper bound, determined from the worst case inputs to the algorithm. The term "analysis of algorithms" was coined by Donald Knuth. Algorithm analysis is an important part of a broader ...
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Numerical Integration
In analysis, numerical integration comprises a broad family of algorithms for calculating the numerical value of a definite integral, and by extension, the term is also sometimes used to describe the numerical solution of differential equations. This article focuses on calculation of definite integrals. The term numerical quadrature (often abbreviated to ''quadrature'') is more or less a synonym for ''numerical integration'', especially as applied to one-dimensional integrals. Some authors refer to numerical integration over more than one dimension as cubature; others take ''quadrature'' to include higher-dimensional integration. The basic problem in numerical integration is to compute an approximate solution to a definite integral :\int_a^b f(x) \, dx to a given degree of accuracy. If is a smooth function integrated over a small number of dimensions, and the domain of integration is bounded, there are many methods for approximating the integral to the desired precision. ...
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Electrical Conductance
The electrical resistance of an object is a measure of its opposition to the flow of electric current. Its reciprocal quantity is , measuring the ease with which an electric current passes. Electrical resistance shares some conceptual parallels with mechanical friction. The SI unit of electrical resistance is the ohm (), while electrical conductance is measured in siemens (S) (formerly called the 'mho' and then represented by ). The resistance of an object depends in large part on the material it is made of. Objects made of electrical insulators like rubber tend to have very high resistance and low conductance, while objects made of electrical conductors like metals tend to have very low resistance and high conductance. This relationship is quantified by resistivity or conductivity. The nature of a material is not the only factor in resistance and conductance, however; it also depends on the size and shape of an object because these properties are extensive rather than inten ...
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Capacitor
A capacitor is a device that stores electrical energy in an electric field by virtue of accumulating electric charges on two close surfaces insulated from each other. It is a passive electronic component with two terminals. The effect of a capacitor is known as capacitance. While some capacitance exists between any two electrical conductors in proximity in a circuit, a capacitor is a component designed to add capacitance to a circuit. The capacitor was originally known as the condenser, a term still encountered in a few compound names, such as the ''condenser microphone''. The physical form and construction of practical capacitors vary widely and many types of capacitor are in common use. Most capacitors contain at least two electrical conductors often in the form of metallic plates or surfaces separated by a dielectric medium. A conductor may be a foil, thin film, sintered bead of metal, or an electrolyte. The nonconducting dielectric acts to increase the capacitor's c ...
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Derivative
In mathematics, the derivative of a function of a real variable measures the sensitivity to change of the function value (output value) with respect to a change in its argument (input value). Derivatives are a fundamental tool of calculus. For example, the derivative of the position of a moving object with respect to time is the object's velocity: this measures how quickly the position of the object changes when time advances. The derivative of a function of a single variable at a chosen input value, when it exists, is the slope of the tangent line to the graph of the function at that point. The tangent line is the best linear approximation of the function near that input value. For this reason, the derivative is often described as the "instantaneous rate of change", the ratio of the instantaneous change in the dependent variable to that of the independent variable. Derivatives can be generalized to functions of several real variables. In this generalization, the derivativ ...
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