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Insys Therapeutics
Insys Therapeutics was an American specialty pharmaceutical company based in Chandler, Arizona. Its main product was Subsys, a sublingual liquid form of the drug fentanyl. Fentanyl is an extremely fast-acting and powerful opioid used to relieve peaks of pain in cancer patients. Founded in 1990, the company and its executives are facing legal issues related to the opioid crisis and marketing activities by the company, including accusations of bribes and misleading advertising. Several company executives were convicted of racketeering in a jury trial rendered in May 2019. Insys filed for bankruptcy in 2019. The filing came just 10 days after the company agreed to pay $225 million to settle separate criminal and civil cases brought by the U.S. Justice Department. Products In addition to Subsys, Insys Therapeutics marketed Syndros, a synthetic THC product, and was working toward approval of other cannabis derivatives. Despite delta-9 THC being classified as a Schedule I sub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chandler, Arizona
Chandler is a city in Maricopa County, Arizona, United States, and a suburb in the Phoenix-Mesa-Chandler Metropolitan Statistical Area (MSA). It is bordered to the north and west by Tempe, to the north by Mesa, to the west by Phoenix, to the south by the Gila River Indian Community, and to the east by Gilbert. As of the 2020 census, the population of Chandler was 275,987, up from 236,123 at the 2010 census. History In 1891, Dr. Alexander John Chandler, the first veterinary surgeon in Arizona Territory, settled on a ranch south of Mesa, studying irrigation engineering. By 1900, he had acquired of land, and began drawing up plans for a townsite on what was then known as the Chandler Ranch. The townsite office opened on May 16, 1912. (Soon after celebrating Chandler's Centennial on May 17, 2012, Chandler Museum staff discovered that the city had been celebrating the wrong date. In May 1912, the ''Chandler Arizonan'' newspaper had erroneously published the founding day as Ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anorexia (symptom)
Anorexia is a medical term for a loss of appetite. While the term in non-scientific publications is often used interchangeably with anorexia nervosa, many possible causes exist for a loss of appetite, some of which may be harmless, while others indicate a serious clinical condition or pose a significant risk. Anorexia is a symptom, not a diagnosis. Anorexia is not to be confused with the mental health disorder anorexia nervosa. Because the term 'anorexia' is often used as a short-form of anorexia nervosa, to avoid confusion a provider must clarify to a patient whether they are simply referring to a decreased appetite or the mental health disorder. Anyone can manifest anorexia as a loss of appetite, regardless of their gender, age, or weight. The symptom also occurs in other animals, such as cats, dogs, cattle, goats, and sheep. In these species, anorexia may be referred to as inappetence. As in humans, loss of appetite can be due to a range of diseases and conditions, as well as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Appeal To Emotion
Appeal to emotion or ''argumentum ad passiones'' (meaning the same in Latin) is an informal fallacy characterized by the manipulation of the recipient's emotions in order to win an argument, especially in the absence of factual evidence. This kind of appeal to emotion is a type of red herring and encompasses several logical fallacies, including appeal to consequences, appeal to fear, appeal to flattery, appeal to pity, appeal to ridicule, appeal to spite, and wishful thinking. The appeal to emotion is only fallacious when the emotions that are elicited are irrelevant to evaluating the truth of the conclusion and serve to distract from rational consideration of relevant premises or information. For instance, if a student says "If I fail this paper I will lose my scholarship. It's not plagiarized." the emotions elicited by the first statement are not relevant to establishing whether the paper was plagiarized. Also, "Look at the suffering children. We must do more for refugees." is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Marijuana
Medical cannabis, or medical marijuana (MMJ), is cannabis and cannabinoids that are prescribed by physicians for their patients. The use of cannabis as medicine has not been rigorously tested due to production and governmental restrictions, resulting in limited clinical research to define the safety and efficacy of using cannabis to treat diseases. Preliminary evidence has indicated that cannabis might reduce nausea and vomiting during chemotherapy and reduce chronic pain and muscle spasms. Regarding non-inhaled cannabis or cannabinoids, a 2021 review found that it provided little relief against chronic pain and sleep disturbance, and caused several transient adverse effects, such as cognitive impairment, nausea, and drowsiness. Short-term use increases the risk of minor and major adverse effects. Common side effects include dizziness, feeling tired, vomiting, and hallucinations. Long-term effects of cannabis are not clear. Concerns include memory and cognition problems, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Decriminalization Of Non-medical Cannabis In The United States
In the United States, the non-medical use of cannabis is legalized in 21 states (plus Guam, the Northern Mariana Islands, and the District of Columbia) and decriminalized in 10 states (plus the U.S. Virgin Islands) as of November 2022. ''Decriminalization'' refers to a policy of reduced penalties for cannabis offenses, typically involving a civil penalty for possessing small amounts (similar to how a minor traffic violation is treated), instead of criminal prosecution or the threat of arrest. In jurisdictions without penalty the policy is referred to as ''legalization'', although the term ''decriminalization'' is sometimes used for this purpose as well. During a wave of decriminalization in the 1970s, Oregon became the first state to decriminalize cannabis in 1973. Ten more states followed by the end of 1978, influenced by the Shafer Commission's endorsement of decriminalization in 1972. By the end of the decade the tide had turned in the other direction, however, and no sta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Federal Jury
A citizen’s right to a trial by jury is a central feature of the United States Constitution. It is considered a fundamental principle of the American legal system. Laws and regulations governing jury selection and conviction/acquittal requirements vary from state to state (and are not available in courts of American Samoa), but the fundamental right itself is mentioned five times in the Constitution: Once in the original text ( Article III, Section 2) and four times in the Bill of Rights (in the Fifth, the Sixth, and the Seventh Amendments). The American system utilizes three types of juries: Investigative grand juries, charged with determining whether enough evidence exists to warrant a criminal indictment; petit juries (also known as a trial jury), which listen to the evidence presented during the course of a criminal trial and are charged with determining the guilt or innocence of the accused party; and civil juries, which are charged with evaluating civil lawsuits. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scott Hadland
Scott E. Hadland (born November 19, 1981) is an American physician and scientist who serves as a pediatrician, and addiction specialist at Massachusetts General Hospital and Harvard Medical School, where he is the Chief of the Division of Adolescent and Young Adult Medicine. He previously served as an addiction specialist at the Grayken Center for Addiction at Boston Medical Center. A key finding of Hadland's research has been to confirm that an increase in dollars spent on marketing from the pharmaceutical industry to American doctors was linked to mortality from opioid overdoses one year later. Hadland’s writing on various health-related topics has appeared in USA Today, CNN and Newsweek. He has also appeared on CNN News to discuss COVID-19 related issues and quoted by ABC News. Research A series of studies led by Hadland provide evidence linking the marketing of opioids directly to doctors, and the addiction epidemic in the United States. Counties where opioid manufactur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Claire McCaskill
Claire Conner McCaskill (; born July 24, 1953) is an American politician who served as a United States Senator from Missouri from 2007 to 2019 and as State Auditor of Missouri from 1999 to 2007. McCaskill is a native of Rolla, Missouri. She graduated from the University of Missouri and the University of Missouri School of Law. A member of the Democratic Party, McCaskill served as a member of the Missouri House of Representatives from 1983 to 1989, as Jackson County Prosecutor from 1993 to 1998, and as the 34th State Auditor of Missouri from 1999 to 2007. She ran for Governor of Missouri in the 2004 election, defeating Democratic incumbent Bob Holden in the Democratic primary and losing to Republican Matt Blunt in a close general election. McCaskill was first elected to the U.S. Senate in 2006. While the second female senator to have represented Missouri, she is the first female candidate to actually have been elected to the Senate from Missouri. (Jean Carnahan was appointed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deloitte
Deloitte Touche Tohmatsu Limited (), commonly referred to as Deloitte, is an international professional services network headquartered in London, England. Deloitte is the largest professional services network by revenue and number of professionals in the world and is considered one of the Big Four accounting firms along with EY (Ernst & Young), KPMG and PricewaterhouseCoopers (PWC). The firm was founded by William Welch Deloitte in London in 1845 and expanded into the United States in 1890. It merged with Haskins & Sells to form Deloitte Haskins & Sells in 1972 and with Touche Ross in the US to form Deloitte & Touche in 1989. In 1993, the international firm was renamed Deloitte Touche Tohmatsu, later abbreviated to Deloitte. In 2002, Arthur Andersen's practice in the UK as well as several of that firm's practices in Europe and North and South America agreed to merge with Deloitte. Subsequent acquisitions have included Monitor Group, a large strategy consulting business, in Janu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deloitte Fast 500
The Deloitte Technology Fast 500 Awards are run and moderated by international professional services group Deloitte Touche Tohmatsu Limited. They recognize the 500 fastest-growing technology companies in regions around the world. Winners include both public and private companies. The awards were created in 1997 during the dotcom boom to illustrate the success of growing U.S. technology companies. Today, the Fast 500 has expanded beyond the United States and covers North America; Asia Pacific; and Europe, the Middle East and Africa (EMEA). The Fast 500 examines companies on their relative growth in revenue In accounting, revenue is the total amount of income generated by the sale of goods and services related to the primary operations of the business. Commercial revenue may also be referred to as sales or as turnover. Some companies receive reven ... over a three-year period. A company that grew by $1million from a revenue of $2million will rank below a company that grew by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Initial Public Offering
An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investment banks, who also arrange for the shares to be listed on one or more stock exchanges. Through this process, colloquially known as ''floating'', or ''going public'', a privately held company is transformed into a public company. Initial public offerings can be used to raise new equity capital for companies, to monetize the investments of private shareholders such as company founders or private equity investors, and to enable easy trading of existing holdings or future capital raising by becoming publicly traded. After the IPO, shares are traded freely in the open market at what is known as the free float. Stock exchanges stipulate a minimum free float both in absolute terms (the total value as determined by the share price multiplied by the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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