Immediate Early Genes
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Immediate Early Genes
Immediate early genes (IEGs) are genes which are activated transiently and rapidly in response to a wide variety of cellular stimuli. They represent a standing response mechanism that is activated at the transcription level in the first round of response to stimuli, before any new proteins are synthesized. IEGs are distinct from "late response" genes, which can only be activated later, following the synthesis of early response gene products. Thus IEGs have been called the "gateway to the genomic response". The term can describe viral regulatory proteins that are synthesized following viral infection of a host cell, or cellular proteins that are made immediately following stimulation of a resting cell by extracellular signals. In their role as "gateways to genomic response", many IEG products are natural transcription factors or other DNA-binding proteins. However, other important classes of IEG products include secreted proteins, cytoskeletal proteins, and receptor subunits. Ne ...
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Airport
An airport is an aerodrome with extended facilities, mostly for commercial air transport. Airports usually consists of a landing area, which comprises an aerially accessible open space including at least one operationally active surface such as a runway for a plane to take off and to land or a helipad, and often includes adjacent utility buildings such as control towers, hangars and terminals, to maintain and monitor aircraft. Larger airports may have airport aprons, taxiway bridges, air traffic control centres, passenger facilities such as restaurants and lounges, and emergency services. In some countries, the US in particular, airports also typically have one or more fixed-base operators, serving general aviation. Operating airports is extremely complicated, with a complex system of aircraft support services, passenger services, and aircraft control services contained within the operation. Thus airports can be major employers, as well as important hubs for tourism ...
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