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Identifiers.org
Identifiers.org is a project providing stable and perennial identifiers for data records used in the Life Sciences. The identifiers are provided in the form of Uniform Resource Identifiers (URIs). Identifiers.org is also a resolving system, that relies on collections listed in the MIRIAM Registry to provide direct access to different instances of the identified records. Identifiers.org URIs and resolving system The Identifiers.org URIs are perennial identifiers, that specify at once the data collection, using the namespaces of the Registry, and the record identifier within the collection in the form of a unique resolvable URI. The Identifiers.org resolving system is built upon the information stored in the MIRIAM Registry, which is a database that stores namespaces assigned to commonly used data collections (databases and ontologies) for the Life Sciences. It transforms an Identifiers.org URI into the various URLs leading to the various instances of the record identified by the U ...
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MIRIAM Registry
The MIRIAM Registry, a by-product of the MIRIAM Guidelines, is a database of namespaces and associated information that is used in the creation of uniform resource identifiers. It contains the set of community-approved namespaces for databases and resources serving, primarily, the biological sciences domain. These shared namespaces, when combined with 'data collection' identifiers, can be used to create globally unique identifiers for knowledge held in data repositories. For more information on the use of URIs to annotate models, see the specification oSBML Level 2 Version 2(and above). A 'data collection' is defined as a set of data which is generated by a provider. A 'resource' is defined as a distributor of that data. Such a description allows numerous resources to be associated with a single collection, allowing accurate representation of how biological information is available on the World Wide Web; often the same information, from a single data collection, may be mirrored by di ...
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Uniform Resource Identifiers
A Uniform Resource Identifier (URI) is a unique sequence of characters that identifies a logical or physical resource used by web technologies. URIs may be used to identify anything, including real-world objects, such as people and places, concepts, or information resources such as web pages and books. Some URIs provide a means of locating and retrieving information resources on a network (either on the Internet or on another private network, such as a computer filesystem or an Intranet); these are Uniform Resource Locators (URLs). A URL provides the location of the resource. A URI identifies the resource by name at the specified location or URL. Other URIs provide only a unique name, without a means of locating or retrieving the resource or information about it, these are Uniform Resource Names (URNs). The web technologies that use URIs are not limited to web browsers. URIs are used to identify anything described using the Resource Description Framework (RDF), for example, conce ...
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Science And Technology In Cambridgeshire
Science is a systematic endeavor that builds and organizes knowledge in the form of testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence for scientific reasoning is tens of thousands of years old. The earliest written records in the history of science come from Ancient Egypt and Mesopotamia in around 3000 to 1200 BCE. Their contributions to mathematics, astronomy, and medicine entered and shaped Greek natural philosophy of classical antiquity, whereby formal attempts were made to provide explanations of events in the physical world based on natural causes. After the fall of the Western Roman Empire, knowledge of Greek conceptions of the world deteriorated in Western Europe during the early centuries (400 to 1000 CE) of the Middle Ages, but was preserved in the Muslim world during the Islamic Golden Age and later by the efforts of Byzantine Greek scholars who brought Greek ma ...
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Metadata
Metadata is "data that provides information about other data", but not the content of the data, such as the text of a message or the image itself. There are many distinct types of metadata, including: * Descriptive metadata – the descriptive information about a resource. It is used for discovery and identification. It includes elements such as title, abstract, author, and keywords. * Structural metadata – metadata about containers of data and indicates how compound objects are put together, for example, how pages are ordered to form chapters. It describes the types, versions, relationships, and other characteristics of digital materials. * Administrative metadata – the information to help manage a resource, like resource type, permissions, and when and how it was created. * Reference metadata – the information about the contents and quality of statistical data. * Statistical metadata – also called process data, may describe processes that collect, process, or produce st ...
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Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ...
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Persistent Uniform Resource Locator
A persistent uniform resource locator (PURL) is a uniform resource locator (URL) (i.e., location-based uniform resource identifier or URI) that is used to redirect to the location of the requested web resource. PURLs redirect HTTP clients using HTTP status codes. Originally, PURLs were recognizable for being hosted apurl.orgor other hostnames containing purl. Early on many of those other hosts used descendants of the original OCLC PURL system software. Eventually, however, the ''PURL concept'' came to be generic and was used to designate any redirection service (named ''PURL resolver'') that: * has a "root URL" as the ''resolver'' reference (e.g. http://myPurlResolver.example); * provides means, to its user-community, to include new ''names'' in the root URL (e.g. http://myPurlResolver.example/name22); * provides means to associate each ''name'' with its URL (to be redirected), and to update this redirection-URL; * ensure the persistence (e.g. by contract) of the root URL and th ...
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LSID
Life Science Identifiers are a way to name and locate pieces of information on the web. Essentially, an LSID is a unique identifier for some data, and the LSID protocol specifies a standard way to locate the data (as well as a standard way of describing that data). They are a little like DOIs used by many publishers. An LSID is represented as a uniform resource name (URN) with the following format: * urn:lsid::: The ''lsid:'' namespace, however, is not registered with the Internet Assigned Numbers Authority (IANA), and so these are not strictly URNs or URIs. LSIDs may be resolved in URLs, e.g. http://zoobank.org/urn:lsid:zoobank.org:pub:CDC8D258-8F57-41DC-B560-247E17D3DC8C Controversy over the use of LSIDs There has been a lot of interest in LSIDs in both the bioinformatics and the biodiversity communities, with the latter continuing to use them as a way of identifying species in global catalogues. However, more recently, as understanding has increased of how HTTP URIs can perfo ...
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CellML
CellML is an XML based markup language for describing mathematical models. Although it could theoretically describe any mathematical model, it was originally created with the Physiome Project in mind, and hence used primarily to describe models relevant to the field of biology. This is reflected in its name CellML, although this is simply a name, not an abbreviation. CellML is growing in popularity as a portable description format for computational models, and groups throughout the world are using CellML for modelling or developing software tools based on CellML. CellML is similar to Systems Biology Markup Language SBML but provides greater scope for model modularity and reuse, and is not specific to descriptions of biochemistry. History The CellML language grew from a need to share models of cardiac cell dynamics among researchers at a number of sites across the world. The original working group formed in 1998 consisted of David Bullivant, Warren Hedley, and Poul Nielsen; all th ...
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BioModels
BioModels is a free and open-source repository for storing, exchanging and retrieving quantitative models of biological interest created in 2006. All the models in the curated section of BioModels Database have been described in peer-reviewed scientific literature. The models stored in BioModels' curated branch are compliant with MIRIAM, the standard of model curation and annotation. The models have been simulated by curators to check that when run in simulations, they provide the same results as described in the publication. Model components are annotated, so the users can conveniently identify each model element and retrieve further information from other resources. Modellers can submit the models in SBML and CellML. Models can subsequently be downloaded in SBMLVCML


Digital Object Identifier
A digital object identifier (DOI) is a persistent identifier or handle used to uniquely identify various objects, standardized by the International Organization for Standardization (ISO). DOIs are an implementation of the Handle System; they also fit within the URI system ( Uniform Resource Identifier). They are widely used to identify academic, professional, and government information, such as journal articles, research reports, data sets, and official publications. DOIs have also been used to identify other types of information resources, such as commercial videos. A DOI aims to resolve to its target, the information object to which the DOI refers. This is achieved by binding the DOI to metadata about the object, such as a URL where the object is located. Thus, by being actionable and interoperable, a DOI differs from ISBNs or ISRCs which are identifiers only. The DOI system uses the indecs Content Model for representing metadata. The DOI for a document remains fixed over t ...
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PURL
A persistent uniform resource locator (PURL) is a uniform resource locator (URL) (i.e., location-based uniform resource identifier or URI) that is used to redirect to the location of the requested web resource. PURLs redirect HTTP clients using HTTP status codes. Originally, PURLs were recognizable for being hosted apurl.orgor other hostnames containing purl. Early on many of those other hosts used descendants of the original OCLC PURL system software. Eventually, however, the ''PURL concept'' came to be generic and was used to designate any redirection service (named ''PURL resolver'') that: * has a "root URL" as the ''resolver'' reference (e.g. http://myPurlResolver.example); * provides means, to its user-community, to include new ''names'' in the root URL (e.g. http://myPurlResolver.example/name22); * provides means to associate each ''name'' with its URL (to be redirected), and to update this redirection-URL; * ensure the persistence (e.g. by contract) of the root URL and t ...
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Uniform Resource Name
A Uniform Resource Name (URN) is a Uniform Resource Identifier (URI) that uses the scheme. URNs are globally unique persistent identifiers assigned within defined namespaces so they will be available for a long period of time, even after the resource which they identify ceases to exist or becomes unavailable. URNs cannot be used to directly locate an item and need not be resolvable, as they are simply templates that another parser may use to find an item. URIs, URNs, and URLs URNs were originally conceived to be part of a three-part information architecture for the Internet, along with Uniform Resource Locators (URLs) and Uniform Resource Characteristics (URCs), a metadata framework. As described in RFC 1737 (1994), and later in RFC 2141 (1997), URNs were distinguished from URLs, which identify resources by specifying their locations in the context of a particular access protocol, such as HTTP or FTP. In contrast, URNs were conceived as persistent, location-independent ident ...
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