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INGEB
Institute for Genetic Engineering and Biotechnology (INGEB) is a Bosnian public research institute, member of Sarajevo University (UNSA), and affiliate center of International Centre for Genetic Engineering and Biotechnology (ICGEB). ICGEB was established as a special project of the United Nations Industrial Development Organization (UNIDO). INGEB was founded under the name "Center for Genetic Engineering and Biotechnology", in 1988. INGEB's headquarters are located in Sarajevo. One of INGEB's most prominent founders was Professor Rifat Hadžiselimović, with the support of the Government of Socialist Republic of Bosnia and Herzegovina, ANUBiH and the biggest B&H economic systems. After the establishment document, INGEB was entrusted with the functions maker, institutional creator and carrier of the overall scientific and professional work in the development of genetic engineering and biotechnology based molecular biology in B&H.Hadžiselimović, R. Ed. (1986). "Dr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rifat Hadžiselimović
Academician Rifat Hadžiselimović is a Bosnian geneticist. He was born in Šiprage, Bosnia and Herzegovina on 7 January 1944. In 2013, with over 45 years of service, he was appointed Emeritus. He acts as scientific adviser in Institute for Genetic Engineering and Biotechnology, University of Sarajevo. Rifat Hadžiselimović is the member of Academy of Sciences and Arts of Bosnia and Herzegovina since 2018. Education and Professional Career Rifat Hadžiselimović completed secondary education in Banja Luka after which in 1962 he enrolled at the Faculty of Natural Sciences and Mathematics in Sarajevo. He graduated as a Biology teacher in 1966 and completed his master's degree in Biology (Anthropology) in 1971 at the Faculty of Science and Mathematics, University of Zagreb, Croatia. His Master thesis was entitled "Historical aspect of the change of relative frequency of two allelogens in human populations". He completed his PhD in biology in 1976 at the Faculty of Science, U ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Sarajevo
The University of Sarajevo ( Bosnian, Croatian and Serbian: ''Univerzitet u Sarajevu'' / Sveučilište u Sarajevu / Универзитет у Сарајеву) is a public university located in Sarajevo, Bosnia and Herzegovina. It is the largest and oldest university in the country, tracing its initial origins to 1537 as an Islamic madrasa. With 20 faculties, three academies and three faculties of theology and with 30,866 enrolled students as of 2014, it ranks among the largest universities in the Balkans in terms of enrollment. Since opening its doors in 1949, a total of 122,000 students received bachelor's degrees, 3,891 received master's degrees and 2,284 received doctorate degrees in 45 different fields. It is now widely regarded as the most prestigious university in Bosnia and Herzegovina, and employs more than one thousand faculty members. History Ottoman period, late Medieval-early Modern Before establishment of modern University of Sarajevo, first schools of higher ed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research
Research is "creativity, creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, Discovery (observation), discovery, interpretation (philosophy), interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemology, epistemologies, which vary considerably both within and between humanities and sciences. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DNA Profiling
DNA profiling (also called DNA fingerprinting) is the process of determining an individual's DNA characteristics. DNA analysis intended to identify a species, rather than an individual, is called DNA barcoding. DNA profiling is a forensic technique in criminal investigations, comparing criminal suspects' profiles to DNA evidence so as to assess the likelihood of their involvement in the crime. It is also used in paternity testing, to establish immigration eligibility, and in genealogical and medical research. DNA profiling has also been used in the study of animal and plant populations in the fields of zoology, botany, and agriculture. Background Starting in the 1980s, scientific advances allowed the use of DNA as a material for the identification of an individual. The first patent covering the direct use of DNA variation for forensicsUS5593832A was filed by Jeffrey Glassberg in 1983, based upon work he had done while at Rockefeller University in the United States in 1981. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Complex Traits
Complex traits, also known as quantitative traits, are traits that do not behave according to simple Mendelian inheritance laws. More specifically, their inheritance cannot be explained by the genetic segregation of a single gene. Such traits show a continuous range of variation and are influenced by both environmental and genetic factors. Compared to strictly Mendelian traits, complex traits are far more common, and because they can be hugely polygenic, they are studied using statistical techniques such as QTL mapping rather than classical genetics methods. Examples of complex traits include height, circadian rhythms, enzyme kinetics, and many diseases including diabetes and Parkinson's disease. One major goal of genetic research today is to better understand the molecular mechanisms through which genetic variants act to influence complex traits. History When Mendel’s work on inheritance was rediscovered in 1900, scientists debated whether Mendel’s laws could account for t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, protein or non-coding RNA, and ultimately affect a phenotype, as the final effect. These products are often proteins, but in non-protein-coding genes such as transfer RNA (tRNA) and small nuclear RNA (snRNA), the product is a functional non-coding RNA. Gene expression is summarized in the central dogma of molecular biology first formulated by Francis Crick in 1958, further developed in his 1970 article, and expanded by the subsequent discoveries of reverse transcription and RNA replication. The process of gene expression is used by all known life—eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses—to generate the macromolecular machinery for life. In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Oncology
Molecular oncology is an interdisciplinary medical specialty at the interface of medicinal chemistry and oncology that refers to the investigation of the chemistry of cancer and tumors at the molecular scale. Also the development and application of molecularly targeted therapies. Main branches Molecular oncology has identified genes that are involved in the development of cancer. The research combined diverse techniques ranging from genomics, computational biology, tumour imaging, in vitro and in vivo functional models to study biological and clinical phenotypes. The proteins produced by these genes may serve as targets for novel chemotherapy drugs and other cancer treatments, or imaging scans. Scientists use a range of techniques to validate the role of the novel candidate genes in the development of cancer. The ultimate aim is to translate these findings into improved treatment options for cancer patients. Gene Targets There are many different genes being researched for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polymerase Chain Reaction
The polymerase chain reaction (PCR) is a method widely used to rapidly make millions to billions of copies (complete or partial) of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount to study in detail. PCR was invented in 1983 by the American biochemist Kary Mullis at Cetus Corporation; Mullis and biochemist Michael Smith (chemist), Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of Ancient DNA, ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skeletal
A skeleton is the structural frame that supports the body of an animal. There are several types of skeletons, including the exoskeleton, which is the stable outer shell of an organism, the endoskeleton, which forms the support structure inside the body, and the hydroskeleton, a flexible internal skeleton supported by fluid pressure. Vertebrates are animals with a vertebral column, and their skeletons are typically composed of bone and cartilage. Invertebrates are animals that lack a vertebral column. The skeletons of invertebrates vary, including hard exoskeleton shells, plated endoskeletons, or spicules. Cartilage is a rigid connective tissue that is found in the skeletal systems of vertebrates and invertebrates. Etymology The term ''skeleton'' comes . ''Sceleton'' is an archaic form of the word. Classification Skeletons can be defined by several attributes. Solid skeletons consist of hard substances, such as bone, cartilage, or cuticle. These can be further divided by loca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Archaeological
Archaeology or archeology is the scientific study of human activity through the recovery and analysis of material culture. The archaeological record consists of artifacts, architecture, biofacts or ecofacts, sites, and cultural landscapes. Archaeology can be considered both a social science and a branch of the humanities. It is usually considered an independent academic discipline, but may also be classified as part of anthropology (in North America – the four-field approach), history or geography. Archaeologists study human prehistory and history, from the development of the first stone tools at Lomekwi in East Africa 3.3 million years ago up until recent decades. Archaeology is distinct from palaeontology, which is the study of fossil remains. Archaeology is particularly important for learning about prehistoric societies, for which, by definition, there are no written records. Prehistory includes over 99% of the human past, from the Paleolithic until the adven ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Analysis
Genetic analysis is the overall process of studying and researching in fields of science that involve genetics and molecular biology. There are a number of applications that are developed from this research, and these are also considered parts of the process. The base system of analysis revolves around general genetics. Basic studies include identification of genes and inherited disorders. This research has been conducted for centuries on both a large-scale physical observation basis and on a more microscopic scale. Genetic analysis can be used generally to describe methods both used in and resulting from the sciences of genetics and molecular biology, or to applications resulting from this research. Genetic analysis may be done to identify genetic/inherited disorders and also to make a differential diagnosis in certain somatic diseases such as cancer. Genetic analyses of cancer include detection of mutations, fusion genes, and DNA copy number changes. History of genetic analysi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Forensic Genetics
DNA profiling (also called DNA fingerprinting) is the process of determining an individual's DNA characteristics. DNA analysis intended to identify a species, rather than an individual, is called DNA barcoding. DNA profiling is a forensic technique in criminal investigations, comparing criminal suspects' profiles to DNA evidence so as to assess the likelihood of their involvement in the crime. It is also used in paternity testing, to establish immigration eligibility, and in genealogical and medical research. DNA profiling has also been used in the study of animal and plant populations in the fields of zoology, botany, and agriculture. Background Starting in the 1980s, scientific advances allowed the use of DNA as a material for the identification of an individual. The first patent covering the direct use of DNA variation for forensicsUS5593832A was filed by Jeffrey Glassberg in 1983, based upon work he had done while at Rockefeller University in the United States in 1981. B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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