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IL12RB1
IL-1 may refer to: * Interleukin 1, a protein * Illinois's 1st congressional district * Illinois Route 1 * Building 1 of Infinite Loop (street) The Apple Campus is the former corporate headquarters of Apple Inc. from 1993 until 2017, when it was largely replaced by Apple Park, though it is still used by Apple as office and lab space. The campus is located at 1 Infinite Loop in Cupertino ..., the headquarters of Apple Inc. * Ilyushin Il-1, a Soviet fighter prototype {{Letter-NumberCombDisambig ...
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Interleukin 1
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Discovery Discovery of these cytokines began with studies on the pathogenesis of fever. The studies were performed by Eli Menkin and Paul Beeson in 1943–1948 on the fever-producing properties of proteins released from rabbit peritoneal exudate cells. These studies were followed by contributions of several investigators, who were primarily interested in the link between fever and infection/inflammation. The basis for the term "interleukin" was to streamline the growing number of biological properties attributed to soluble factors from macrophages and lymphocytes. IL-1 was the name given to the macrophage product, whereas IL-2 was used to define the lymphocyte product. At the time of the assignment of these names, there was no amino acid sequence analysis known and the terms were used to define bio ...
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Illinois's 1st Congressional District
Illinois's first congressional district is a congressional district in the U.S. state of Illinois. Based in Cook County, the district includes much of the South Side of Chicago, and continues southwest to Joliet. From 2003 to early 2013 it extended into the city's southwest suburbs until reaching the border of Will County, and covered , making it one of the 40 smallest districts in the U.S. (although there are four smaller districts in Illinois). The district had a population that was 65% African American, the highest percentage of any congressional district in the nation, but that percentage has now declined to 52%. It includes the home of former President Barack Obama. The 1st is a majority-minority district, and has been since at least the 1920s. In 1929, it became the first district in the 20th century to send an African American to Congress when Republican Oscar Stanton De Priest was elected to represent the district. The 1st has been represented by an African American M ...
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Illinois Route 1
Illinois Route 1 (IL 1) is a state highway in the U.S. state of Illinois. Running parallel to the Indiana border, the highway starts at the free ferry crossing to Kentucky at Cave-in-Rock on the Ohio River and runs north to the south side of Chicago as Halsted Street at an intersection with Interstate 57. This is a distance of . Route description Cave-in-Rock to Birds IL 1 begins at the ferry dock for the Cave-in-Rock Ferry in the eponymous village of Cave-in-Rock along the Ohio River. A continuation of Kentucky Route 91 (KY 91), IL 1 begins its journey in the Shawnee National Forest, leaving the village of Cave-in-Rock for the hamlet of Loves Crossing, where it meets the eastern terminus of IL 146. For the next , IL 1 winds north through the forest, reaching a junction with IL 13, which connects to Equality and Shawneetown. Further north, IL 1 remains a two-lane road when it junctions with IL 141 at the Gallatin–Whi ...
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Infinite Loop (street)
The Apple Campus is the former corporate headquarters of Apple Inc. from 1993 until 2017, when it was largely replaced by Apple Park, though it is still used by Apple as office and lab space. The campus is located at 1 Infinite Loop in Cupertino, California, United States. Its design resembles that of a university, with the buildings arranged around green spaces, similar to a suburban business park. History and founding Apple's corporate headquarters was originally located at Building 1 on 20525 Mariani Ave in Cupertino. The land east of Mariani One across De Anza Boulevard where the campus was built was originally occupied by the company Four-Phase Systems (later acquired by Motorola). It has an area of . Construction began in 1992 and was completed in 1993 by the Sobrato Development Company. Before 1997, activities held on the campus were exclusively research and development. Until that time the buildings were referred to as R&D 1–6. With the return of Steve Jobs to Apple ...
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