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IKK Ichigan
IKK may refer to: * IκB kinase, an enzyme * Greater Kankakee Airport Greater Kankakee Airport is a public use airport located three nautical miles (6 km) south of the central business district of Kankakee, a city in Kankakee County, Illinois, United States. It is included in the National Plan of Integr ... * Ikk (film), a 2021 Indian film {{dab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
IκB Kinase
The IκB kinase (IkappaB kinase or IKK) is an enzyme complex that is involved in propagating the cellular response to inflammation. The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates the NF-κB transcription factor by masking the nuclear localization signals (NLS) of NF-κB proteins and keeping them sequestered in an inactive state in the cytoplasm. Specifically, IKK phosphorylates the inhibitory IκBα protein. This phosphorylation results in the dissociation of IκBα from NF-κB. NF-κB, which is now free, migrates into the nucleus and activates the expression of at least 150 genes; some of which are anti-apoptotic. Catalyzed reaction In enzymology, an IκB kinase () is an enzyme that catalyzes the chemical reaction: :ATP + IκB protein \rightleftharpoons ADP + IκB phosphoprotein Thus, the two substrates of this enzyme are ATP and IκB protein, whereas its two ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Greater Kankakee Airport
Greater Kankakee Airport is a public use airport located three nautical miles (6 km) south of the central business district of Kankakee, a city in Kankakee County, Illinois, United States. It is included in the National Plan of Integrated Airport Systems for 2011–2015, which categorized it as a ''general aviation'' facility. The airport was opened in 1962 and continues to operate as a general aviation facility serving the Kankakee area and South Chicago. It is south of Chicago and north of Champaign, Illinois. It is the largest airport between the Chicago Midway Airport and the Champaign Airport. Greater Kankakee is a general aviation airport, consisting of mostly private aircraft with a mix of corporate and business aircraft usage. The airport is owned and operated by the Kankakee Valley Airport Authority. The authority has an appointed board of directors totaling six members: three members from the Kankakee County Board and one each from the communities of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |