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Interventricular Septum
The interventricular septum (IVS, or ventricular septum, or during development septum inferius) is the stout wall separating the ventricles, the lower chambers of the heart, from one another. The ventricular septum is directed obliquely backward to the right and curved with the convexity toward the right ventricle; its margins correspond with the anterior and posterior interventricular sulci. The lower part of the septum, which is the major part, is thick and muscular, and its much smaller upper part is thin and membraneous. During each cardiac cycle the interventricular septum contracts by shortening longitudinally and becoming thicker. Structure The interventricular septum is the stout wall separating the ventricles, the lower chambers of the heart, from one another. The ventricular septum is directed obliquely backward to the right and curved with the convexity toward the right ventricle; its margins correspond with the anterior and posterior longitudinal sulci. The gr ...
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Heart
The heart is a muscular organ in most animals. This organ pumps blood through the blood vessels of the circulatory system. The pumped blood carries oxygen and nutrients to the body, while carrying metabolic waste such as carbon dioxide to the lungs. In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the chest. In humans, other mammals, and birds, the heart is divided into four chambers: upper left and right atria and lower left and right ventricles. Commonly the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. Fish, in contrast, have two chambers, an atrium and a ventricle, while most reptiles have three chambers. In a healthy heart blood flows one way through the heart due to heart valves, which prevent backflow. The heart is enclosed in a protective sac, the pericardium, which also contains a small amount of fluid. The wall ...
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Right Atrium
The atrium ( la, ātrium, , entry hall) is one of two upper chambers in the heart that receives blood from the circulatory system. The blood in the atria is pumped into the heart ventricles through the atrioventricular valves. There are two atria in the human heart – the left atrium receives blood from the pulmonary circulation, and the right atrium receives blood from the venae cavae of the systemic circulation. During the cardiac cycle the atria receive blood while relaxed in diastole, then contract in systole to move blood to the ventricles. Each atrium is roughly cube-shaped except for an ear-shaped projection called an atrial appendage, sometimes known as an auricle. All animals with a closed circulatory system have at least one atrium. The atrium was formerly called the 'auricle'. That term is still used to describe this chamber in some other animals, such as the ''Mollusca''. They have thicker muscular walls than the atria do. Structure Humans have a four-chambered h ...
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Ventricular Hypertrophy
Ventricular hypertrophy (VH) is thickening of the walls of a ventricle (lower chamber) of the heart. Although left ventricular hypertrophy (LVH) is more common, right ventricular hypertrophy (RVH), as well as concurrent hypertrophy of both ventricles can also occur. Ventricular hypertrophy can result from a variety of conditions, both adaptive and maladaptive. For example, it occurs in what is regarded as a physiologic, adaptive process in pregnancy in response to increased blood volume; but can also occur as a consequence of ventricular remodeling following a heart attack. Importantly, pathologic and physiologic remodeling engage different cellular pathways in the heart and result in different gross cardiac phenotypes. Presentation In individuals with eccentric hypertrophy there may be little or no indication that hypertrophy has occurred as it is generally a healthy response to increased demands on the heart. Conversely, concentric hypertrophy can make itself known in a variety ...
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Acyanotic Heart Defect
An acyanotic heart defect, is a class of congenital heart defects. In these, blood is shunted (flows) from the left side of the heart to the right side of the heart, most often due to a structural defect (hole) in the interventricular septum. People often retain normal levels of oxyhemoglobin saturation in systemic circulation. This term is outdated, because a person with an acyanotic heart defect may show cyanosis (turn blue due to insufficient oxygen in the blood). Signs and symptoms Presentation is the following: * Shortness of breath * Congested cough * Diaphoresis * Fatigue * Frequent respiratory infections * Machine-like heart murmur * Tachycardia * Tachypnea * Respiratory distress * Mild cyanosis (in right sided heart failure) * Poor growth and development (from increased energy spent on breathing) Complications This condition can cause congestive heart failure. Diagnosis Types Left to right shunting heart defects include: * Ventricular septal defect (VSD) (30% o ...
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Cardiac Shunt
A cardiac shunt is a pattern of blood flow in the heart that deviates from the normal circuit of the circulatory system. It may be described as right-left, left-right or bidirectional, or as systemic-to-pulmonary or pulmonary-to-systemic. The direction may be controlled by left and/or right heart pressure, a biological or artificial heart valve or both. The presence of a shunt may also affect left and/or right heart pressure either beneficially or detrimentally. Terminology The left and right sides of the heart are named from a dorsal view, i.e., looking at the heart from the back or from the perspective of the person whose heart it is. There are four chambers in a heart: an atrium (upper) and a ventricle (lower) on both the left and right sides. In mammals and birds, blood from the body goes to the right side of the heart first. Blood enters the upper right atrium, is pumped down to the right ventricle and from there to the lungs via the pulmonary artery. Blood going to the lungs ...
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Tetralogy Of Fallot
Tetralogy of Fallot (TOF), formerly known as Steno-Fallot tetralogy, is a congenital heart defect characterized by four specific cardiac defects. Classically, the four defects are: *pulmonary stenosis, which is narrowing of the exit from the right ventricle; * a ventricular septal defect, which is a hole allowing blood to flow between the two ventricles; * right ventricular hypertrophy, which is thickening of the right ventricular muscle; and * an overriding aorta, which is where the aorta expands to allow blood from both ventricles to enter. At birth, children may be asymptomatic or present with many severe symptoms. Later in infancy, there are typically episodes of bluish colour to the skin due to a lack of sufficient oxygenation, known as cyanosis. When affected babies cry or have a bowel movement, they may undergo a "tet spell" where they turn cyanotic, have difficulty breathing, become limp, and occasionally lose consciousness. Other symptoms may include a heart murmur, ...
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Congenital Heart Defect
A congenital heart defect (CHD), also known as a congenital heart anomaly and congenital heart disease, is a defect in the structure of the heart or great vessels that is present at birth. A congenital heart defect is classed as a cardiovascular disease. Signs and symptoms depend on the specific type of defect. Symptoms can vary from none to life-threatening. When present, symptoms may include rapid breathing, bluish skin (cyanosis), poor weight gain, and feeling tired. CHD does not cause chest pain. Most congenital heart defects are not associated with other diseases. A complication of CHD is heart failure. The cause of a congenital heart defect is often unknown. Risk factors include certain infections during pregnancy such as rubella, use of certain medications or drugs such as alcohol or tobacco, parents being closely related, or poor nutritional status or obesity in the mother. Having a parent with a congenital heart defect is also a risk factor. A number of genetic conditio ...
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Ventricular Septal Defect
A ventricular septal defect (VSD) is a defect in the ventricular septum, the wall dividing the left and right ventricles of the heart. The extent of the opening may vary from pin size to complete absence of the ventricular septum, creating one common ventricle. The ventricular septum consists of an inferior muscular and superior membranous portion and is extensively innervated with conducting cardiomyocytes. The membranous portion, which is close to the atrioventricular node, is most commonly affected in adults and older children in the United States. It is also the type that will most commonly require surgical intervention, comprising over 80% of cases. Membranous ventricular septal defects are more common than muscular ventricular septal defects, and are the most common congenital cardiac anomaly. Signs and symptoms Ventricular septal defect is usually symptomless at birth. It usually manifests a few weeks after birth. VSD is an acyanotic congenital heart defect, aka a lef ...
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Left Coronary Artery
The left coronary artery (LCA) is a coronary artery that arises from the aorta above the left cusp of the aortic valve, and feeds blood to the left side of the heart muscle. It is also known as the left main coronary artery (LMCA) and the left main stem coronary artery (LMS). Branching The left coronary artery typically runs for 10 to 25 mm, and then bifurcates into the left anterior descending artery (also called the widow maker) and the left circumflex artery. Sometimes, an additional artery arises at the bifurcation of the left main artery, forming a trifurcation; this extra artery is called the ''ramus'' or ''intermediate artery''. The part that is between the aorta and the bifurcation only is known as the left main artery (LM), while the term "LCA" might refer to just the left main, or to the left main and all its eventual branches. A "first septal branch" is sometimes described. Additional images File:Coronary arteries 1.jpg, Left coronary artery File:Cardiac vess ...
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Left Anterior Descending Artery
The left anterior descending artery (also LAD, anterior interventricular branch of left coronary artery, or anterior descending branch) is a branch of the left coronary artery. Blockage of this artery is often called the ''widow-maker infarction'' due to a high death risk. Structure It passes at first behind the pulmonary artery and then comes forward between that vessel and the left atrium to reach the anterior interventricular sulcus, along which it descends to the notch of cardiac apex. Although rare, multiple anomalous courses of the LAD have been described. These include the origin of the artery from the right aortic sinus. In 78% of cases, it reaches the apex of the heart. Branches The LAD gives off two types of branches: ''septals'' and ''diagonals''. * Septals originate from the LAD at 90 degrees to the surface of the heart, perforating and supplying the anterior 2/3 of the interventricular septum. * Diagonals run along the surface of the heart and supply the lateral ...
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Right Coronary Artery
In the blood supply of the heart, the right coronary artery (RCA) is an artery originating above the right cusp of the aortic valve, at the right aortic sinus in the heart. It travels down the right coronary sulcus, towards the crux of the heart. It supplies the right side of the heart, and the interventricular septum. Structure The right coronary artery originates above the right aortic sinus above the aortic valve. It passes through the right coronary sulcus (right atrioventricular groove), towards the crux of the heart. It gives off many branches, including the posterior interventricular artery, the right marginal artery, the conus artery, and the sinoatrial nodal artery. Segments * Proximal: starting at RCA origin, spanning half the distance to the acute margin * Middle: from proximal segment to the acute margin * Distal: from middle segment to origination point of the posterior interventricular artery, where the posterior interventricular sulcus meets the atrioven ...
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Posterior Interventricular Artery
In the coronary circulation, the posterior interventricular artery (PIV, PIA, or PIVA), most often called the posterior descending artery (PDA), is an artery running in the posterior interventricular sulcus to the apex of the heart where it meets with the anterior interventricular artery or also known as Left Anterior Descending artery. It supplies the posterior third of the interventricular septum. The remaining anterior two-thirds is supplied by the anterior interventricular artery which is a septal branch of the left anterior descending artery, which is a branch of left coronary artery. It is typically a branch of the right coronary artery (70%, known as right dominance). Alternately, the PIV can be a branch of the circumflex coronary artery The circumflex branch of left coronary artery, or left circumflex artery or circumflex artery, is a branch of the left coronary artery. Description The left circumflex artery follows the left part of the coronary sulcus, running firs ...
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