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Institut De Recherches Cliniques De Montréal
Institut de recherches cliniques de Montréal (IRCM), (also known, in English, as Montreal Clinical Research Institute), is a medical research institute affiliated with Université de Montréal. Its work focuses mainly on cellular biology, molecular biology, genetics, developmental biology, and proteomics. Its aim is to understand the causes of illnesses and develop new therapeutic solutions or cures. History The institute was established in 1967 by Dr. Jacques Genest who had earlier in 1952 established the first clinical research department at Hôtel-Dieu de Montréal hospital and had become the head of the Faculty of Medicine at McGill University in 1964. With lawyer Marcel Piché, Genest founded ''Centre médical Claude-Bernard'' in 1965, renamed ''Institut de diagnostic et de recherches cliniques de Montréal'' and further changed to ''Institut de recherches cliniques de Montréal'' its present name in 1986. Keeping its links with Hôtel-Dieu de Montréal, the Institute signe ...
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Institut De Recherches Cliniques De Montreal
An institute is an organisational body created for a certain purpose. They are often research organisations (research institute, research institutes) created to do research on specific topics, or can also be a professional body. In some countries, institutes can be part of a university or other institutions of higher education, either as a group of academic department, departments or an autonomous educational institution without a traditional university status such as a "university institute" (see Institute of Technology). In some countries, such as South Korea and India, private schools are sometimes referred to as institutes, and in Spain, secondary schools are referred to as institutes. Historically, in some countries institutes were educational units imparting vocational training and often incorporating libraries, also known as mechanics' institutes. The word "institute" comes from a Latin word ''institutum'' meaning "facility" or "habit"; from ''instituere'' meaning "bui ...
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Université De Montréal
The Université de Montréal (UdeM; ; translates to University of Montreal) is a French-language public research university in Montreal, Quebec, Canada. The university's main campus is located in the Côte-des-Neiges neighborhood of Côte-des-Neiges–Notre-Dame-de-Grâce on Mount Royal near the Outremont Summit (also called Mount Murray), in the borough of Outremont. The institution comprises thirteen faculties, more than sixty departments and two affiliated schools: the Polytechnique Montréal (School of Engineering; formerly the École polytechnique de Montréal) and HEC Montréal (School of Business). It offers more than 650 undergraduate programmes and graduate programmes, including 71 doctoral programmes. The university was founded as a satellite campus of the Université Laval in 1878. It became an independent institution after it was issued a papal charter in 1919 and a provincial charter in 1920. Université de Montréal moved from Montreal's Quartier Latin to its pr ...
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Cellular Biology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such as ca ...
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Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ...
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ...
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Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of Regeneration (biology), regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryogenesis, embryonic development of animals are: tissue patterning (via regional specification and patterned cellular differentiation, cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing ...
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Proteomics
Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In addition, other kinds of proteins include antibodies that protect an organism from infection, and hormones that send important signals throughout the body. The proteome is the entire set of proteins produced or modified by an organism or system. Proteomics enables the identification of ever-increasing numbers of proteins. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefited greatly from the genetic information of various genome projects, including the Human Genome Project. It covers the exploration of proteomes from the overall level of protein composition, structure, and activity, and is an important component of functional genomics. ...
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Jacques Genest
Jacques Genest (May 29, 1919 – January 5, 2018) was a Canadian physician and scientist. He founded the Institut de recherches cliniques de Montréal, Institut de recherches cliniques de Montréal (IRCM) and was an emeritus professor at Université de Montréal and a professor at McGill University. Genest was best known for founding and leading several organizations related to clinical research in Québec and for his work on arterial hypertension. Life and career Born in Montreal, Quebec, Genest received his medical degree from the University of Montreal. He completed his residency in internal medicine and pathology at the Hôpital Hôtel-Dieu de Montréal before heading to Johns Hopkins University, Johns Hopkins in Baltimore, Maryland for a research fellowship. He was then a research associate and assistant physician at the The Rockefeller University, Rockefeller Institute in New York City, which later awarded him an honorary degree in 1986. Upon returning to Quebec, he was ask ...
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Hôtel-Dieu De Montréal
The Hôtel-Dieu de Montréal (founded in 1645) was the first hospital established in Montreal, Quebec, Canada. ''Hôtel-Dieu'', literally translated in English as ''Hotel of God'', is an archaic French term for hospital, referring to the origins of hospitals as religious institutions. Its emergency room and function as an active hospital ended in 2017, and as of 2020 serves as a COVID-19 test site during the COVID-19 pandemic in Montreal. History The origins of the Hôtel-Dieu de Montréal date to the arrival in 1642 of Paul Chomedey and a small party of French settlers on the Island of Montreal to found the French colony of Ville-Marie. Among them was Jeanne Mance, the first nurse in New France. She founded the hospital on October 8, 1645, as confirmed by letters patent of Louis XIV of France in April 1669. In addition to returning to France to seek financial support for the hospital, in 1657 Mance recruited three sisters of the Religious Hospitallers of St. Joseph (Relig ...
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McGill University
McGill University (french: link=no, Université McGill) is an English-language public research university located in Montreal, Quebec, Canada. Founded in 1821 by royal charter granted by King George IV,Frost, Stanley Brice. ''McGill University, Vol. I. For the Advancement of Learning, 1801–1895.'' McGill-Queen's University Press, 1980. the university bears the name of James McGill, a Scottish merchant whose bequest in 1813 formed the university's precursor, University of McGill College (or simply, McGill College); the name was officially changed to McGill University in 1885. McGill's main campus is on the slope of Mount Royal in downtown Montreal in the borough of Ville-Marie, with a second campus situated in Sainte-Anne-de-Bellevue, west of the main campus on Montreal Island. The university is one of two members of the Association of American Universities located outside the United States, alongside the University of Toronto, and is the only Canadian member of the Glob ...
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Eric Kierans
Eric William Kierans (February 2, 1914 – May 10, 2004) was a Canadian economist and politician. Early life Born in Montreal, Kierans grew up in the working-class Saint-Henri neighbourhood. His father worked at Canadian Car and Foundry, and his mother came to Canada as a domestic. From 1927 to 1935, he attended Loyola College. Career After serving as director of the school of commerce at McGill University and president of the Montreal Stock Exchange, Kierans entered provincial politics in 1963. Nicknamed the "Socialist Millionaire," he was appointed Minister of Revenue and then Minister of Health in the Quebec Liberal government of Quebec Premier Jean Lesage during the Quiet Revolution. Kierans became president of the Quebec Liberal Party and clashed with former cabinet minister and colleague René Lévesque in 1967, daring him to give up the idea of Quebec separatism or quit the Liberal Party. Lévesque later quit the Liberal Party and established the ''Mouvement Souver ...
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Marcel-Piché Prize
The Marcel-Piché Prize (French language: ''prix Marcel-Piché'') is awarded to a researcher at the Institut de recherches cliniques de Montréal (IRCM) "in recognition of the quality of iomedicalresearch and in recognition of the contribution to the growth and outreach of the Institute." The prize is named after Marcel Piché, a Montreal lawyer involved with the IRCM. Recipients SourceIRCM*1976 - Wojciech Nowaczynski *1977 - Roger Boucher *1978 - Michel Chrétien *1979 - André Barbeau *1980 - Otto Kuchel *1981 - Jean Davignon *1982 - Shri V. Pande *1983 - Nabil Seidah *1984 - Marc Cantin *1985 - Paul Jolicoeur *1986 - Louis Yves Marcel *1987 - Peter W. Schiller *1988 - Ram Sairam *1989 - Pavel Hamet *1990 - David J. Roy *1991 - Ernesto Luis Schiffrin *1992 - Jacques Drouin *1993 - Rafick-Pierre Sékaly *1994 - Mona Nemer *1995 - Louis-Gilles Durand *1996 - Trang Hoang *1997 - Vincent F. Castellucci *1998 - Jacques Genest *2000 - Guy Sauvageau *2002 - André Veille ...
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