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Insensitive Nuclei Enhanced By Polarization Transfer
Insensitive nuclei enhancement by polarization transfer (INEPT) is a signal enhancement method used in NMR spectroscopy. It involves the transfer of nuclear spin polarization from spins with large Boltzmann population differences to nuclear spins of interest with lower Boltzmann population differences. INEPT uses J-coupling for the polarization transfer in contrast to Nuclear Overhauser effect (NOE), which arises from dipolar cross- relaxation. This method of signal enhancement was introduced by Ray Freeman in 1979. Due to its usefulness in signal enhancement, pulse sequences used in heteronuclear NMR experiments often contain blocks of INEPT or INEPT-like sequences. Background The sensitivity of NMR signal detection depends on the gyromagnetic ratio (γ) of the nucleus. In general, the signal intensity produced from a nucleus with a gyromagnetic ratio of γ is proportional to γ3 because the magnetic moment, the Boltzmann populations, and the nuclear precession frequency all inc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NMR Spectroscopy
Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei. The sample is placed in a magnetic field and the NMR signal is produced by excitation of the nuclei sample with radio waves into nuclear magnetic resonance, which is detected with sensitive radio receivers. The intramolecular magnetic field around an atom in a molecule changes the resonance frequency, thus giving access to details of the electronic structure of a molecule and its individual functional groups. As the fields are unique or highly characteristic to individual compounds, in modern organic chemistry practice, NMR spectroscopy is the definitive method to identify monomolecular organic compounds. The principle of NMR usually involves three sequential steps: # The alignment (polarization) of the magnetic nuclear spins in an applied, constant magnetic field B0. # The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Longman
Longman, also known as Pearson Longman, is a publishing company founded in London, England, in 1724 and is owned by Pearson PLC. Since 1968, Longman has been used primarily as an imprint by Pearson's Schools business. The Longman brand is also used for the Longman Schools in China and the ''Longman Dictionary''. History Beginnings The Longman company was founded by Thomas Longman (1699 – 18 June 1755), the son of Ezekiel Longman (died 1708), a gentleman of Bristol. Thomas was apprenticed in 1716 to John Osborn, a London bookseller, and at the expiration of his apprenticeship married Osborn's daughter. In August 1724, he purchased the stock and household goods of William Taylor, the first publisher of ''Robinson Crusoe'', for 9s 6d. Taylor's two shops in Paternoster Row, London, were known respectively as the '' Black Swan'' and the ''Ship'', premises at that time having signs rather than numbers, and became the publishing house premises. Longman entered into part ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Population Inversion
In science, specifically statistical mechanics, a population inversion occurs while a system (such as a group of atoms or molecules) exists in a state in which more members of the system are in higher, excited states than in lower, unexcited energy states. It is called an "inversion" because in many familiar and commonly encountered physical systems, this is not possible. This concept is of fundamental importance in laser science because the production of a population inversion is a necessary step in the workings of a standard laser. Boltzmann distributions and thermal equilibrium To understand the concept of a population inversion, it is necessary to understand some thermodynamics and the way that light interacts with matter. To do so, it is useful to consider a very simple assembly of atoms forming a laser medium. Assume there is a group of ''N'' atoms, each of which is capable of being in one of two energy states: either #The ''ground state'', with energy ''E''1; or #The ''exc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spin Echo
In magnetic resonance, a spin echo or Hahn echo is the refocusing of spin magnetisation by a pulse of resonant electromagnetic radiation. Modern nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) make use of this effect. The NMR signal observed following an initial excitation pulse decays with time due to both spin relaxation and any ''inhomogeneous'' effects which cause spins in the sample to precess at different rates. The first of these, relaxation, leads to an irreversible loss of magnetisation. But the inhomogeneous dephasing can be removed by applying a 180° ''inversion'' pulse that inverts the magnetisation vectors. Examples of inhomogeneous effects include a magnetic field gradient and a distribution of chemical shifts. If the inversion pulse is applied after a period ''t'' of dephasing, the inhomogeneous evolution will rephase to form an echo at time 2''t''. In simple cases, the intensity of the echo relative to the initial signal is given by ''e– ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
INEPT Pulse Sequence
Insensitive nuclei enhancement by polarization transfer (INEPT) is a signal enhancement method used in NMR spectroscopy. It involves the transfer of nuclear spin polarization from spins with large Boltzmann population differences to nuclear spins of interest with lower Boltzmann population differences. INEPT uses J-coupling for the polarization transfer in contrast to Nuclear Overhauser effect (NOE), which arises from dipolar cross- relaxation. This method of signal enhancement was introduced by Ray Freeman in 1979. Due to its usefulness in signal enhancement, pulse sequences used in heteronuclear NMR experiments often contain blocks of INEPT or INEPT-like sequences. Background The sensitivity of NMR signal detection depends on the gyromagnetic ratio (γ) of the nucleus. In general, the signal intensity produced from a nucleus with a gyromagnetic ratio of γ is proportional to γ3 because the magnetic moment, the Boltzmann populations, and the nuclear precession frequency all incr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Signal-to-noise
Signal-to-noise ratio (SNR or S/N) is a measure used in science and engineering that compares the level of a desired signal to the level of background noise. SNR is defined as the ratio of signal power to the noise power, often expressed in decibels. A ratio higher than 1:1 (greater than 0 dB) indicates more signal than noise. SNR, bandwidth, and channel capacity of a communication channel are connected by the Shannon–Hartley theorem. Definition Signal-to-noise ratio is defined as the ratio of the power of a signal (meaningful input) to the power of background noise (meaningless or unwanted input): : \mathrm = \frac, where is average power. Both signal and noise power must be measured at the same or equivalent points in a system, and within the same system bandwidth. Depending on whether the signal is a constant () or a random variable (), the signal-to-noise ratio for random noise becomes: : \mathrm = \frac where E refers to the expected value, i.e. in this case th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gyromagnetic Ratio
In physics, the gyromagnetic ratio (also sometimes known as the magnetogyric ratio in other disciplines) of a particle or system is the ratio of its magnetic moment to its angular momentum, and it is often denoted by the symbol , gamma. Its SI unit is the radian per second per tesla (rad⋅s−1⋅T−1) or, equivalently, the coulomb per kilogram (C⋅kg−1). The term "gyromagnetic ratio" is often used as a synonym for a ''different'' but closely related quantity, the -factor. The -factor only differs from the gyromagnetic ratio in being dimensionless. For a classical rotating body Consider a nonconductive charged body rotating about an axis of symmetry. According to the laws of classical physics, it has both a magnetic dipole moment due to the movement of charge and an angular momentum due to the movement of mass arising from its rotation. It can be shown that as long as its charge and mass density and flow are distributed identically and rotationally symmetric, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Signal-to-noise Ratio
Signal-to-noise ratio (SNR or S/N) is a measure used in science and engineering that compares the level of a desired signal to the level of background noise. SNR is defined as the ratio of signal power to the noise power, often expressed in decibels. A ratio higher than 1:1 (greater than 0 dB) indicates more signal than noise. SNR, bandwidth, and channel capacity of a communication channel are connected by the Shannon–Hartley theorem. Definition Signal-to-noise ratio is defined as the ratio of the power of a signal (meaningful input) to the power of background noise (meaningless or unwanted input): : \mathrm = \frac, where is average power. Both signal and noise power must be measured at the same or equivalent points in a system, and within the same system bandwidth. Depending on whether the signal is a constant () or a random variable (), the signal-to-noise ratio for random noise becomes: : \mathrm = \frac where E refers to the expected value, i.e. in this case ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Precession
Precession is a change in the orientation of the rotational axis of a rotating body. In an appropriate reference frame it can be defined as a change in the first Euler angle, whereas the third Euler angle defines the rotation itself. In other words, if the axis of rotation of a body is itself rotating about a second axis, that body is said to be precessing about the second axis. A motion in which the second Euler angle changes is called ''nutation''. In physics, there are two types of precession: torque-free and torque-induced. In astronomy, ''precession'' refers to any of several slow changes in an astronomical body's rotational or orbital parameters. An important example is the steady change in the orientation of the axis of rotation of the Earth, known as the precession of the equinoxes. Torque-free Torque-free precession implies that no external moment (torque) is applied to the body. In torque-free precession, the angular momentum is a constant, but the angular velocit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spin (physics)
Spin is a conserved quantity carried by elementary particles, and thus by composite particles (hadrons) and atomic nucleus, atomic nuclei. Spin is one of two types of angular momentum in quantum mechanics, the other being ''orbital angular momentum''. The orbital angular momentum operator is the quantum-mechanical counterpart to the classical angular momentum of orbital revolution and appears when there is periodic structure to its wavefunction as the angle varies. For photons, spin is the quantum-mechanical counterpart of the Polarization (waves), polarization of light; for electrons, the spin has no classical counterpart. The existence of electron spin angular momentum is inferred from experiments, such as the Stern–Gerlach experiment, in which silver atoms were observed to possess two possible discrete angular momenta despite having no orbital angular momentum. The existence of the electron spin can also be inferred theoretically from the spin–statistics theorem and from th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magnetic Moment
In electromagnetism, the magnetic moment is the magnetic strength and orientation of a magnet or other object that produces a magnetic field. Examples of objects that have magnetic moments include loops of electric current (such as electromagnets), permanent magnets, elementary particles (such as electrons), various molecules, and many astronomical objects (such as many planets, some moons, stars, etc). More precisely, the term ''magnetic moment'' normally refers to a system's magnetic dipole moment, the component of the magnetic moment that can be represented by an equivalent magnetic dipole: a magnetic north and south pole separated by a very small distance. The magnetic dipole component is sufficient for small enough magnets or for large enough distances. Higher-order terms (such as the magnetic quadrupole moment) may be needed in addition to the dipole moment for extended objects. The magnetic dipole moment of an object is readily defined in terms of the torque that the objec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pulse Sequence
In Fourier transform NMR spectroscopy and imaging, a pulse sequence describes a series of radio frequency pulses applied to the sample, such that the free induction decay is related to the characteristic frequencies of the desired signals. After applying a Fourier transform, the signal can be represented in the frequency domain as the NMR spectrum. In magnetic resonance imaging, additional '' gradient pulses'' are applied by switching magnetic fields that exhibit a space-dependent gradient which can be used to reconstruct spatially resolved images after applying Fourier transforms. The outcome of pulse sequences is often analyzed using the product operator formalism. See also * Spin echo * Insensitive nuclei enhanced by polarization transfer * MRI sequence An MRI sequence in magnetic resonance imaging (MRI) is a particular setting of pulse sequences and pulsed field gradients, resulting in a particular image appearance. A multiparametric MRI is a combination of two or more ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
