Hypericum Sect. Hypericum
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Hypericum Sect. Hypericum
''Hypericum'' is a genus of flowering plants in the family Hypericaceae (formerly considered a subfamily of Clusiaceae). The genus has a nearly worldwide distribution, missing only from tropical lowlands, deserts and polar regions. Many ''Hypericum'' species are regarded as invasive species and noxious weeds. All members of the genus may be referred to as St. John's wort, and some are known as goatweed. The white or pink flowered marsh St. John's worts of North America and eastern Asia are generally accepted as belonging to the separate genus ''Triadenum'' Raf. ''Hypericum'' is unusual for a genus of its size because a worldwide taxonomic monograph was produced for it by Norman Robson (working at the Natural History Museum, London). Robson recognizes 36 sections within ''Hypericum''. Description ''Hypericum'' species are quite variable in habit, occurring as trees, shrubs, annuals, and perennials. Trees in the sense of single stemmed woody plants are rare, as most woody s ...
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Hypericum Perforatum
''Hypericum perforatum'', known as St. John's wort, is a flowering plant in the family Hypericaceae and the type species of the genus '' Hypericum''. Possibly a hybrid between '' H. maculatum'' and '' H. attenuatum'', the species can be found across temperate areas of Eurasia and has been introduced as an invasive weed to much of North and South America, as well as South Africa and Australia. While the species is harmful to livestock and can interfere with prescription drugs, it has been used in folk medicine over centuries, and remains commercially cultivated in the 21st century. Hyperforin, a phytochemical constituent of the species, is under basic research for possible therapeutic properties. Description ''Hypericum perforatum'' is an herbaceous perennial plant with extensive, creeping rhizomes. Its reddish stems are erect and branched in the upper section, and can grow up to high. The stems are woody near their base and may appear jointed from leaf scars. The branche ...
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Invasive Species
An invasive species otherwise known as an alien is an introduced organism that becomes overpopulated and harms its new environment. Although most introduced species are neutral or beneficial with respect to other species, invasive species adversely affect habitats and bioregions, causing ecological, environmental, and/or economic damage. The term can also be used for native species that become harmful to their native environment after human alterations to its food webfor example the purple sea urchin ('' Strongylocentrotus purpuratus'') which has decimated kelp forests along the northern California coast due to overharvesting of its natural predator, the California sea otter (''Enhydra lutris''). Since the 20th century, invasive species have become a serious economic, social, and environmental threat. Invasion of long-established ecosystems by organisms is a natural phenomenon, but human-facilitated introductions have greatly increased the rate, scale, and geographic range ...
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Hyperforin
Hyperforin is a phytochemical produced by some of the members of the plant genus '' Hypericum'', notably '' Hypericum perforatum'' (St John's wort). Hyperforin may be involved in the pharmacological effects of St. John's wort, specifically in its antidepressant effects. Occurrence Hyperforin has only been found in significant amounts in '' Hypericum perforatum'' with other related species such as ''Hypericum calycinum'' containing lower levels of the phytochemical. It accumulates in oil glands, pistils, and fruits, probably as a plant defensive compound. The first natural extractions were done with ethanol and afforded a 7:1 yield of crude extract to phytochemical however, this technique produced a mixture of hyperforin and adhyperforin. The extraction technique has since been modernized using lipophilic liquid CO2 extraction to afford a 3:1 crude to phytochemical extraction which is then further purified away from adhyperforin. This CO2 extraction is rather tricky still because ...
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Phloroglucinol
Phloroglucinol is an organic compound with the formula C6H3(OH)3. It is a colorless solid. It is used in the synthesis of pharmaceuticals and explosives. Phloroglucinol is one of three isomeric benzenetriols. The other two isomers are hydroxyquinol (1,2,4-benzenetriol) and pyrogallol (1,2,3-benzenetriol). Phloroglucinol, and its benzenetriol isomers, are still defined as "phenols" according to the IUPAC official nomenclature rules of chemical compounds. Many such monophenolics are often termed "polyphenols" by the cosmetic and parapharmaceutical industries, which does not match the scientifically accepted definition. Synthesis and occurrence In 1855, phloroglucinol was first prepared from phloretin by the Austrian chemist Heinrich Hlasiwetz (1825–1875). A modern synthesis of involves hydrolysis of benzene-1,3,5-triamine and its derivatives. Representative is the following route from trinitrobenzene. : The synthesis is noteworthy because ordinary aniline derivatives are un ...
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John And Paul
John and Paul (Latin: ''Ioannes, Paulus'') are saints who lived during the fourth century in the Roman Empire. They were martyred at Rome on 26 June. The year of their martyrdom is uncertain according to their ''Acts''; it occurred under Julian the Apostate (361–3). Hagiography In the second half of the fourth century, Byzantius, the Roman senator, and Saint Pammachius, his son, fashioned their house on the Cælian Hill into a Christian basilica. In the fifth century the ''presbyteri tituli Byzantii'' (priests of the church of Byzantius) are mentioned in an inscription and among the signatures of the Roman Council of 499. The church was also called the ''titulus Pammachii'' after Byzantius's son, the pious friend of St. Jerome.Kirsch, Johann Peter. "Sts. John and Paul." The Catholic Encyclope ...
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Paracelsus
Paracelsus (; ; 1493 – 24 September 1541), born Theophrastus von Hohenheim (full name Philippus Aureolus Theophrastus Bombastus von Hohenheim), was a Swiss physician, alchemist, lay theologian, and philosopher of the German Renaissance. He was a pioneer in several aspects of the " medical revolution" of the Renaissance, emphasizing the value of observation in combination with received wisdom. He is credited as the "father of toxicology". Paracelsus also had a substantial influence as a prophet or diviner, his "Prognostications" being studied by Rosicrucians in the 1600s. Paracelsianism is the early modern medical movement inspired by the study of his works. Biography Paracelsus was born in Egg an der Sihl, a village close to the Etzel Pass in Einsiedeln, Schwyz. He was born in a house right next to a bridge across the Sihl river (known as ''Teufelsbrücke''). The historical house, dated to the 14th century, was destroyed in 1814. The ''Restaurant Krone'' now stands in it ...
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Hypericin
Hypericin is a naphthodianthrone, an anthraquinone derivative which, together with hyperforin, is one of the principal active constituents of '' Hypericum'' ( Saint John's wort). Hypericin is believed to act as an antibiotic, antiviral and non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine. It was initially believed that the anti-depressant pharmacological activity of hypericin was due to inhibition of monoamine oxidase enzyme. The crude extract of ''Hypericum'' is a weak inhibitor of MAO-A and MAO-B. Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors. This points in the direction that other constituents are responsible for the MAOI effect. The current belief is that the mechanism of antidepressant activity is due to the inhibition of re-uptake of certain neurotransmitters. ...
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Naphthodianthrone
''For the parent molecule 9,10-anthraquinone, see anthraquinone'' Anthraquinones (also known as anthraquinonoids) are a class of naturally occurring phenolic compounds based on the 9,10-anthraquinone skeleton. They are widely used industrially and occur naturally. Occurrence in plants : Natural pigments that are derivatives of anthraquinone are found, inter alia, in aloe latex, senna, rhubarb, and cascara buckthorn, fungi, lichens, and some insects. A type II polyketide synthase is responsible for anthraquinone biosynthesis in the bacterium '' Photorhabdus luminescens''. Chorismate, formed by isochorismate synthase in the shikimate pathway, is a precursor of anthraquinones in ''Morinda citrifolia''. Tests for anthraquinones in natural extracts have been established. *Senna glycosides from the senna. *Frangulin in Frangula alnus. * Aloe-emodin in aloe resin. * Carmine, a bright-red pigment derived from insects. *Hypericin and fagopyrin are naphthodianthrones, anthraquino ...
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Taproot
A taproot is a large, central, and dominant root from which other roots sprout laterally. Typically a taproot is somewhat straight and very thick, is tapering in shape, and grows directly downward. In some plants, such as the carrot, the taproot is a storage organ so well developed that it has been cultivated as a vegetable. The taproot system contrasts with the adventitious or fibrous root system of plants with many branched roots, but many plants that grow a taproot during germination go on to develop branching root structures, although some that rely on the main root for storage may retain the dominant taproot for centuries, for example ''Welwitschia''.Taproot also store nutrition. Plants with taproots are often vegetables. Description Dicots, one of the two divisions of flowering plants (angiosperms), start with a taproot, which is one main root forming from the enlarging radicle of the seed. The tap root can be persistent throughout the life of the plant but is most oft ...
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Natural History Museum, London
The Natural History Museum in London is a museum that exhibits a vast range of specimens from various segments of natural history. It is one of three major museums on Exhibition Road in South Kensington, the others being the Science Museum and the Victoria and Albert Museum. The Natural History Museum's main frontage, however, is on Cromwell Road. The museum is home to life and earth science specimens comprising some 80 million items within five main collections: botany, entomology, mineralogy, palaeontology and zoology. The museum is a centre of research specialising in taxonomy, identification and conservation. Given the age of the institution, many of the collections have great historical as well as scientific value, such as specimens collected by Charles Darwin. The museum is particularly famous for its exhibition of dinosaur skeletons and ornate architecture—sometimes dubbed a ''cathedral of nature''—both exemplified by the large ''Diplodocus'' cast that dom ...
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