Hermann Otto Laurenz Fischer
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Hermann Otto Laurenz Fischer
Hermann Otto Laurenz Fischer (16 December 1888 – 9 March 1960) was a German American professor of biochemistry and son of Emil Fischer. Fischer's work was on synthesis and the determination of structures of organic compounds. Fischer was born the eldest son in Würzburg to Emil Fischer, professor of chemistry, and Agnes Gerlach. The family moved to Berlin in 1892 where Fischer went to the Gymnasium. While the other two brothers sought medical careers, he chose chemistry, studying in Cambridge in 1907 after being impressed by Sir William Ramsay who had made a family visit. He then joining for military service. He then went to the University of Berlin and later Jena where he studied tautomerism of diketones under Ludwig Knorr. He then went to Berlin to study under his father and was involved in the synthesis of didepsides. World War I led to all the brothers being drafted, with Hermann joining a chemical warfare unit. His two brothers died during the war. and in 1919 his father di ...
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Emil Fischer
Hermann Emil Louis Fischer (; 9 October 1852 – 15 July 1919) was a German chemist and 1902 recipient of the Nobel Prize in Chemistry. He discovered the Fischer esterification. He also developed the Fischer projection, a symbolic way of drawing asymmetric carbon atoms. He also hypothesized lock and key mechanism of enzyme action. He never used his first given name, and was known throughout his life simply as Emil Fischer. Early years and career Fischer was born in Euskirchen, near Cologne, the son of Laurenz Fischer, a businessman, and his wife Julie Poensgen. After graduating he wished to study natural sciences, but his father compelled him to work in the family business until determining that his son was unsuitable. Fischer then attended the University of Bonn in 1871, but switched to the University of Strasbourg in 1872. He earned his doctorate in 1874 under Adolf von Baeyer with his study of phthaleins, and was appointed to a position at the university. After eight ye ...
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Würzburg
Würzburg (; Main-Franconian: ) is a city in the region of Franconia in the north of the German state of Bavaria. Würzburg is the administrative seat of the ''Regierungsbezirk'' Lower Franconia. It spans the banks of the Main River. Würzburg is situated approximately east-southeast of Frankfurt am Main and approximately west-northwest of Nuremberg (). The population (as of 2019) is approximately 130,000 residents. The administration of the ''Landkreis Würzburg'' ( district of Würzburg) is also located in the town. The regional dialect is East Franconian. History Early and medieval history A Bronze Age (Urnfield culture) refuge castle, the Celtic Segodunum,Koch, John T. (2020)CELTO-GERMANIC Later Prehistory and Post-Proto-Indo-European vocabulary in the North and West p. 131 and later a Roman fort, stood on the hill known as the Leistenberg, the site of the present Fortress Marienberg. The former Celtic territory was settled by the Alamanni in the 4th or 5th century ...
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William Ramsay
Sir William Ramsay (; 2 October 1852 – 23 July 1916) was a Scottish chemist who discovered the noble gases and received the Nobel Prize in Chemistry in 1904 "in recognition of his services in the discovery of the inert gaseous elements in air" along with his collaborator, John William Strutt, 3rd Baron Rayleigh, who received the Nobel Prize in Physics that same year for their discovery of argon. After the two men identified argon, Ramsay investigated other atmospheric gases. His work in isolating argon, helium, neon, krypton, and xenon led to the development of a new section of the periodic table. Early years Ramsay was born at 2 Clifton StreetGlasgow Post Office Directory 1852 in Glasgow on 2 October 1852, the son of civil engineer and surveyor, William C. Ramsay, and his wife, Catherine Robertson. The family lived at 2 Clifton Street in the city centre, a three-storey and basement Georgian townhouse. The family moved to 1 Oakvale Place in the Hillhead district in his ...
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Humboldt University Of Berlin
Humboldt-Universität zu Berlin (german: Humboldt-Universität zu Berlin, abbreviated HU Berlin) is a German public research university in the central borough of Mitte in Berlin. It was established by Frederick William III on the initiative of Wilhelm von Humboldt, Johann Gottlieb Fichte and Friedrich Ernst Daniel Schleiermacher as the University of Berlin () in 1809, and opened in 1810, making it the oldest of Berlin's four universities. From 1828 until its closure in 1945, it was named Friedrich Wilhelm University (german: Friedrich-Wilhelms-Universität). During the Cold War, the university found itself in East Berlin and was ''de facto'' split in two when the Free University of Berlin opened in West Berlin. The university received its current name in honour of Alexander and Wilhelm von Humboldt in 1949. The university is divided into nine faculties including its medical school shared with the Freie Universität Berlin. The university has a student enrollment of around 32 ...
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Tautomer
Tautomers () are structural isomers (constitutional isomers) of chemical compounds that readily interconvert. The chemical reaction interconverting the two is called tautomerization. This conversion commonly results from the relocation of a hydrogen atom within the compound. The phenomenon of tautomerization is called tautomerism, also called desmotropism. Tautomerism is for example relevant to the behavior of amino acids and nucleic acids, two of the fundamental building blocks of life. Care should be taken not to confuse tautomers with depictions of "contributing structures" in chemical resonance. Tautomers are distinct chemical species that can be distinguished by their differing atomic connectivities, molecular geometries, and physicochemical and spectroscopic properties, whereas resonance forms are merely alternative Lewis structure (valence bond theory) depictions of a single chemical species, whose true structure is best described as the "average" of the idealized, hypothe ...
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Ludwig Knorr
Ludwig Knorr (2 December 1859 – 4 June 1921) was a German chemist. Together with Carl Paal, he discovered the Paal–Knorr synthesis, and the Knorr quinoline synthesis and Knorr pyrrole synthesis are also named after him. The synthesis in 1883 of the analgesic drug antipyrine, now called phenazone, was a commercial success. Antipyrine was the first synthetic drug and the most widely used drug until it was replaced by Aspirin in the early 20th century. Early life Ludwig Knorr was born to a wealthy merchant family in 1859. He grew up in the Sabbadini-Knorr company headquarters, located in the Kaufingerstraße in the center of Munich, and in the family house near the Lake Starnberg. After the early death of his father, the education of him and his four brothers lay in the hands of their mother. In 1878 Knorr received his Abitur and started to study chemistry at the University of Munich. In the beginning, he studied under Jacob Volhard; then, after Volhard left for the Universi ...
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Depside
A depside is a type of polyphenolic compound composed of two or more monocyclic aromatic units linked by an ester bond. Depsides are most often found in lichens, but have also been isolated from higher plants, including species of the Ericaceae, Lamiaceae, Papaveraceae and Myrtaceae. Certain depsides have antibiotic, anti- HIV, antioxidant, and anti-proliferative activity ''in vitro''. As inhibitors of prostaglandin synthesis and leukotriene B4 biosynthesis, some depsides have ''in vitro'' anti-inflammatory activity. A depsidase is a type of enzyme that cuts depside bonds. One such enzyme is tannase. Examples Gyrophoric acid, found in the lichen '' Cryptothecia rubrocincta'', is a depside. Merochlorophaeic acid, isolated from lichens of the genus '' Cladonia'', is an inhibitor of prostaglandin synthesis. Some depsides are described as anti-HIV. See also *Salsalate homodimer formed from self-condensation of salicylic acid Salicylic acid is an organic compound with the ...
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University Of Basel
The University of Basel (Latin: ''Universitas Basiliensis'', German: ''Universität Basel'') is a university in Basel, Switzerland. Founded on 4 April 1460, it is Switzerland's oldest university and among the world's oldest surviving universities. The university is traditionally counted among the leading institutions of higher learning in the country. The associated Basel University Library is the largest and among the most important libraries in Switzerland. The university hosts the faculties of theology, law, medicine, humanities and social sciences, science, psychology, and business and economics, as well as numerous cross-disciplinary subjects and institutes, such as the Biozentrum for biomedical research and the Institute for European Global Studies. In 2020, the university had 13,139 students and 378 professors. International students accounted for 27 percent of the student body. In its over 500-year history, the university has been home to Erasmus of Rotterdam, Parac ...
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Frederick Banting
Sir Frederick Grant Banting (November 14, 1891 – February 21, 1941) was a Canadian medical scientist, physician, painter, and Nobel laureate noted as the co-discoverer of insulin and its therapeutic potential. In 1923, Banting and John Macleod received the Nobel Prize in Medicine. Banting shared the honours and award money with his colleague, Charles Best. That same year, the government of Canada granted Banting a lifetime annuity to continue his work. As to this day, Frederick Banting, who received the Nobel Prize at age 32, remains the youngest Nobel laureate for Physiology/Medicine. Early years Frederick Banting was born on November 14, 1891, in a farmhouse near Alliston, Ontario. The youngest of five children of William Thompson Banting and Margaret Grant, he attended public high school in Alliston. In 1910, he started at Victoria College, part of the University of Toronto, in the General Arts program. After failing his first year, he petitioned to join the m ...
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1888 Births
In Germany, 1888 is known as the Year of the Three Emperors. Currently, it is the year that, when written in Roman numerals, has the most digits (13). The next year that also has 13 digits is the year 2388. The record will be surpassed as late as 2888, which has 14 digits. Events January–March * January 3 – The 91-centimeter telescope at Lick Observatory in California is first used. * January 12 – The Schoolhouse Blizzard hits Dakota Territory, the states of Montana, Minnesota, Nebraska, Kansas, and Texas, leaving 235 dead, many of them children on their way home from school. * January 13 – The National Geographic Society is founded in Washington, D.C. * January 21 – The Amateur Athletic Union is founded by William Buckingham Curtis in the United States. * January 26 – The Lawn Tennis Association is founded in England. * February 6 – Gillis Bildt becomes Prime Minister of Sweden (1888–1889). * February 27 – In West O ...
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1960 Deaths
Year 196 ( CXCVI) was a leap year starting on Thursday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Dexter and Messalla (or, less frequently, year 949 ''Ab urbe condita''). The denomination 196 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus attempts to assassinate Clodius Albinus but fails, causing Albinus to retaliate militarily. * Emperor Septimius Severus captures and sacks Byzantium; the city is rebuilt and regains its previous prosperity. * In order to assure the support of the Roman legion in Germany on his march to Rome, Clodius Albinus is declared Augustus by his army while crossing Gaul. * Hadrian's wall in Britain is partially destroyed. China * First year of the '' Jian'an era of the Chinese Han Dynasty. * Emperor Xian o ...
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