Hemodynamics Of The Aorta
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Hemodynamics Of The Aorta
The hemodynamics of the aorta is an ongoing field of research in which the goal is to identify what flow patterns and subsequent forces occur within the thoracic aorta. These patterns and forces are used to identify the presence and severity of cardiovascular diseases such as aortic aneurysm and atherosclerosis. Some of the methods used to study the hemodynamics of aortic flow are patient scans, computational fluid dynamics models, and particle tracking velocimetry (PTV). The information gathered through these studies can be used for surgery planning and the development of implants. Greater understanding of this topic reduces mortality rates associated with cardiovascular disease. General flow patterns The mean velocity in the aorta varies over the cardiac cycle. During systole the mean velocity rises to a peak, then it falls during diastole. This pattern is repeated with each squeezing pulse of the heart. The highest velocities are found at the exit of the valve during systole ...
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Aorta Segments
The aorta ( ) is the main and largest artery in the human body, originating from the left ventricle of the heart and extending down to the abdomen, where it splits into two smaller arteries (the common iliac arteries). The aorta distributes oxygenated blood to all parts of the body through the systemic circulation. Structure Sections In anatomical sources, the aorta is usually divided into sections. One way of classifying a part of the aorta is by anatomical compartment, where the thoracic aorta (or thoracic portion of the aorta) runs from the heart to the diaphragm. The aorta then continues downward as the abdominal aorta (or abdominal portion of the aorta) from the diaphragm to the aortic bifurcation. Another system divides the aorta with respect to its course and the direction of blood flow. In this system, the aorta starts as the ascending aorta, travels superiorly from the heart, and then makes a hairpin turn known as the aortic arch. Following the aortic arch, the ao ...
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Brachiocephalic Artery
The brachiocephalic artery (or brachiocephalic trunk or innominate artery) is an artery of the mediastinum that supplies blood to the right arm and the head and neck. It is the first branch of the aortic arch. Soon after it emerges, the brachiocephalic artery divides into the right common carotid artery and the right subclavian artery. There is no brachiocephalic artery for the left side of the body. The left common carotid, and the left subclavian artery, come directly off the aortic arch. However, there are two brachiocephalic veins. Structure The brachiocephalic artery arises, on a level with the upper border of the second right costal cartilage, from the start of the aortic arch, on a plane anterior to the origin of the left carotid artery. It ascends obliquely upward, backward, and to the right to the level of the upper border of the right sternoclavicular articulation, where it divides into the right common carotid artery and right subclavian arteries. The artery then cros ...
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Footnotes
A note is a string of text placed at the bottom of a page in a book or document or at the end of a chapter, volume, or the whole text. The note can provide an author's comments on the main text or citations of a reference work in support of the text. Footnotes are notes at the foot of the page while endnotes are collected under a separate heading at the end of a chapter, volume, or entire work. Unlike footnotes, endnotes have the advantage of not affecting the layout of the main text, but may cause inconvenience to readers who have to move back and forth between the main text and the endnotes. In some editions of the Bible, notes are placed in a narrow column in the middle of each page between two columns of biblical text. Numbering and symbols In English, a footnote or endnote is normally flagged by a superscripted number immediately following that portion of the text the note references, each such footnote being numbered sequentially. Occasionally, a number between brack ...
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Ventricular Assist Device
A ventricular assist device (VAD) is an electromechanical device for assisting cardiac circulation, which is used either to partially or to completely replace the function of a failing heart. The function of a VAD differs from that of an artificial cardiac pacemaker in that a VAD pumps blood, whereas a pacemaker delivers electrical impulses to the heart muscle. Some VADs are for short-term use, typically for patients recovering from myocardial infarction (heart attack) and for patients recovering from cardiac surgery; some are for long-term use (months to years to perpetuity), typically for patients with advanced heart failure. VADs are designed to assist either the right ventricle (RVAD) or the left ventricle (LVAD), or to assist both ventricles (BiVAD). The type of VAD implanted depends on the type of underlying heart disease, and on the pulmonary arterial resistance, which determines the workload of the right ventricle. The left ventricular assist device (LVAD) is the most com ...
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Refractive Index
In optics, the refractive index (or refraction index) of an optical medium is a dimensionless number that gives the indication of the light bending ability of that medium. The refractive index determines how much the path of light is bent, or refracted, when entering a material. This is described by Snell's law of refraction, , where ''θ''1 and ''θ''2 are the angle of incidence and angle of refraction, respectively, of a ray crossing the interface between two media with refractive indices ''n''1 and ''n''2. The refractive indices also determine the amount of light that is reflected when reaching the interface, as well as the critical angle for total internal reflection, their intensity ( Fresnel's equations) and Brewster's angle. The refractive index can be seen as the factor by which the speed and the wavelength of the radiation are reduced with respect to their vacuum values: the speed of light in a medium is , and similarly the wavelength in that medium is , where ''Π...
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Transparent Ceramics
Many ceramic materials, both glassy and crystalline, have found use as optically transparent materials in various forms from bulk solid-state components to high surface area forms such as thin films, coatings, and fibers. Such devices have found widespread use for various applications in the electro-optical field including: optical fibers for guided lightwave transmission, optical switches, laser amplifiers and lenses, hosts for solid-state lasers and optical window materials for gas lasers, and infrared (IR) heat seeking devices for missile guidance systems and IR night vision. Harris, D.C. (2009) "Materials for Infrared Windows and Domes: Properties and Performance", SPIE PRESS Monograph, Vol. PM70 (Int. Society of Optical Engineers, Bellingham WA) While single-crystalline ceramics may be largely defect-free (particularly within the spatial scale of the incident light wave), optical transparency in polycrystalline materials is limited by the amount of light that is scattered ...
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Particle Tracking Velocimetry
Particle tracking velocimetry (PTV) is a velocimetry method i.e. a technique to measure velocities and trajectories of moving objects. In fluid mechanics research these objects are neutrally buoyant particles that are suspended in fluid flow. As the name suggests, individual particles are tracked, so this technique is a Lagrangian approach, in contrast to particle image velocimetry (PIV), which is an Eulerian method that measures the velocity of the fluid as it passes the observation point, that is fixed in space. There are two experimental PTV methods: * the two-dimensional (2-D) PTV. Measurements are made in a 2-D slice, illuminated by a thin laser sheet (a thin plane); a low density of seeded particles allows for tracking each of them individually for several frames. * the three-dimensional ''particle tracking velocimetry'' (3-D PTV) is a distinctive experimental technique originally developed to study fully turbulent flows. It is now being used widely in various disciplines, ran ...
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Capillary
A capillary is a small blood vessel from 5 to 10 micrometres (μm) in diameter. Capillaries are composed of only the tunica intima, consisting of a thin wall of simple squamous endothelial cells. They are the smallest blood vessels in the body: they convey blood between the arterioles and venules. These microvessels are the site of exchange of many substances with the interstitial fluid surrounding them. Substances which cross capillaries include water, oxygen, carbon dioxide, urea, glucose, uric acid, lactic acid and creatinine. Lymph capillaries connect with larger lymph vessels to drain lymphatic fluid collected in the microcirculation. During early embryonic development, new capillaries are formed through vasculogenesis, the process of blood vessel formation that occurs through a '' de novo'' production of endothelial cells that then form vascular tubes. The term '' angiogenesis'' denotes the formation of new capillaries from pre-existing blood vessels and already present ...
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Windkessel Effect
Windkessel effect is a term used in medicine to account for the shape of the arterial blood pressure waveform in terms of the interaction between the stroke volume and the compliance of the aorta and large elastic arteries (Windkessel vessels) and the resistance of the smaller arteries and arterioles. Windkessel when loosely translated from German to English means 'air chamber', but is generally taken to imply an ''elastic reservoir''. The walls of large elastic arteries (e.g. aorta, common carotid, subclavian, and pulmonary arteries and their larger branches) contain elastic fibers, formed of elastin. These arteries distend when the blood pressure rises during systole and recoil when the blood pressure falls during diastole. Since the rate of blood entering these elastic arteries exceeds that leaving them via the peripheral resistance, there is a net storage of blood in the aorta and large arteries during systole, which discharges during diastole. The compliance (or distensi ...
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Plug Flow
In fluid mechanics, plug flow is a simple model of the velocity profile of a fluid flowing in a pipe. In plug flow, the velocity of the fluid is assumed to be constant across any cross-section of the pipe perpendicular to the axis of the pipe. The plug flow model assumes there is no boundary layer adjacent to the inner wall of the pipe. The plug flow model has many practical applications. One example is in the design of chemical reactors. Essentially no back mixing is assumed with "plugs" of fluid passing through the reactor. This results in differential equations that need to be integrated to find the reactor conversion and outlet temperatures. Other simplifications used are perfect radial mixing and a homogeneous bed structure. An advantage of the plug flow model is that no part of the solution of the problem can be perpetuated "upstream". This allows one to calculate the exact solution to the differential equation knowing only the initial conditions. No further iteration ...
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Phase Contrast Magnetic Resonance Imaging
Phase contrast magnetic resonance imaging (PC-MRI) is a specific type of magnetic resonance imaging used primarily to determine flow velocities. PC-MRI can be considered a method of Magnetic Resonance Velocimetry. It also provides a method of magnetic resonance angiography. Since modern PC-MRI is typically time-resolved, it provides a means of 4D imaging (three spatial dimensions plus time). How it Works Atoms with an odd number of protons or neutrons have a randomly aligned angular spin momentum. When placed in a strong magnetic field, some of these spins align with the axis of the external field, which causes a net 'longitudinal' magnetization. These spins precess about the axis of the external field at a frequency proportional to the strength of that field. Then, energy is added to the system through a Radio frequency (RF) pulse to 'excite' the spins, changing the axis that the spins precess about. These spins can then be observed by receiver coils (Radiofrequency coils) using ...
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Descending Aorta
In human anatomy, the descending aorta is part of the aorta, the largest artery in the body. The descending aorta begins at the aortic arch and runs down through the chest and abdomen. The descending aorta anatomically consists of two portions or segments, the thoracic and the abdominal aorta, in correspondence with the two great cavities of the trunk in which it is situated. Within the abdomen, the descending aorta branches into the two common iliac arteries which serve the pelvis and eventually legs. The ductus arteriosus connects to the junction between the pulmonary artery and the descending aorta in foetal life. This artery later regresses as the ligamentum arteriosum. See also *Abbott artery Abbott's artery describes an anomalous artery that arises from the posteromedial aspect of the proximal part of the descending aorta. Normally a minor congenital abnormality, its presence is important during surgical repair of coarctation of the ... References External links ...
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