Heinrich Köbner
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Heinrich Köbner
Heinrich Koebner (German spelling Köbner); (2 December 1838 – 3 September 1904) was a German-Jewish dermatologist born in Breslau. He studied medicine in Berlin, earning his doctorate in 1859 at Breslau. Afterwards he performed hospital duties in Vienna under Ferdinand von Hebra (1816–1880) and in Paris with Alfred Hardy (1811–1893). In 1876 he became director of the policlinic for syphilis and diseases of the skin at the University of Breslau. In 1884 he established a new policlinic in Berlin, where he provided classes for physicians. Koebner phenomenon Koebner was a renowned dermatologist known for his research of psoriasis, epidermolysis bullosa simplex and various fungal disorders. He is best known for the eponymous "Koebner phenomenon", also known as isomorphic phenomenon. The Koebner phenomenon is the development of isomorphic pathologic lesions in the traumatized "uninvolved skin" of persons who have cutaneous diseases such as psoriasis. In other wor ...
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Heinrich Köbner
Heinrich Koebner (German spelling Köbner); (2 December 1838 – 3 September 1904) was a German-Jewish dermatologist born in Breslau. He studied medicine in Berlin, earning his doctorate in 1859 at Breslau. Afterwards he performed hospital duties in Vienna under Ferdinand von Hebra (1816–1880) and in Paris with Alfred Hardy (1811–1893). In 1876 he became director of the policlinic for syphilis and diseases of the skin at the University of Breslau. In 1884 he established a new policlinic in Berlin, where he provided classes for physicians. Koebner phenomenon Koebner was a renowned dermatologist known for his research of psoriasis, epidermolysis bullosa simplex and various fungal disorders. He is best known for the eponymous "Koebner phenomenon", also known as isomorphic phenomenon. The Koebner phenomenon is the development of isomorphic pathologic lesions in the traumatized "uninvolved skin" of persons who have cutaneous diseases such as psoriasis. In other wor ...
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Pathology
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"), and the affix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomy ...
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Warts
Warts are typically small, rough, hard growths that are similar in color to the rest of the skin. They typically do not result in other symptoms, except when on the bottom of the feet, where they may be painful. While they usually occur on the hands and feet, they can also affect other locations. One or many warts may appear. They are not cancerous. Warts are caused by infection with a type of human papillomavirus (HPV). Factors that increase the risk include use of public showers and pools, working with meat, eczema and a weak immune system. The virus is believed to enter the body through skin that has been damaged slightly. A number of types exist, including "common warts", plantar warts, " filiform warts", and genital warts. Genital warts are often sexually transmitted. Without treatment, most types of warts resolve in months to years. A number of treatments may speed resolution, including salicylic acid applied to the skin and cryotherapy. In those who are otherwise hea ...
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Renbök Phenomenon
In the field of dermatology, the Renbök phenomenon is a phenomenon where one skin condition inhibits another. It is also known as the reverse Koebner phenomenon. The term was first used by Happle et al. in 1991. The word "Renbök" is a neologism, made from a reversal of the letters of the name "Köbner". See also * Koebner phenomenon References Dermatologic signs {{dermatology-stub ...
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Reverse Koebner Phenomenon
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Koebnerization
The Koebner phenomenon or Köbner phenomenon (, ), also called the Koebner response or the isomorphic response, attributed to Heinrich Köbner, is the appearance of skin lesions on lines of trauma. The Koebner phenomenon may result from either a linear exposure or irritation. Conditions demonstrating linear lesions after a linear exposure to a causative agent include: molluscum contagiosum, warts and toxicodendron dermatitis (a dermatitis caused by a genus of plants including poison ivy). Warts and molluscum contagiosum lesions can be spread in linear patterns by self-scratching (" auto-inoculation"). Toxicodendron dermatitis lesions are often linear from brushing up against the plant. Causes of the Koebner phenomenon that are secondary to scratching rather than an infective or chemical cause include vitiligo, psoriasis, lichen planus, lichen nitidus, pityriasis rubra pilaris, and keratosis follicularis (Darier disease). Definition The Koebner phenomenon describes ...
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Lichen Planus
Lichen planus (LP) is a chronic inflammatory and immune-mediated disease that affects the skin, nails, hair, and mucous membranes. It is not an actual lichen, and is only named that because it looks like one. It is characterized by polygonal, flat-topped, violaceous papules and plaques with overlying, reticulated, fine white scale ( Wickham's striae), commonly affecting dorsal hands, flexural wrists and forearms, trunk, anterior lower legs and oral mucosa. The hue may be gray-brown in people with darker skin. Although there is a broad clinical range of LP manifestations, the skin and oral cavity remain as the major sites of involvement. The cause is unknown, but it is thought to be the result of an autoimmune process with an unknown initial trigger. There is no cure, but many different medications and procedures have been used in efforts to control the symptoms. The term lichenoid reaction (lichenoid eruption or lichenoid lesion) refers to a lesion of similar or identical histopa ...
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Vitiligo
Vitiligo is a disorder that causes the skin to lose its color. Specific causes are unknown but studies suggest a link to immune system changes. Signs and symptoms The only sign of vitiligo is the presence of pale patchy areas of depigmented skin which tend to occur on the extremities. Some people may experience itching before a new patch occurs. The patches are initially small, but often grow and change shape. When skin lesions occur, they are most prominent on the face, hands and wrists. The loss of skin pigmentation is particularly noticeable around body orifices, such as the mouth, eyes, nostrils, genitalia and Navel, umbilicus. Some lesions have hyperpigmentation, increased skin pigment around the edges. Those affected by vitiligo who are Stigmatization, stigmatized for their condition may experience depression and similar mood disorders. File:Vitiligo03.jpg, Vitiligo on lighter skin File:Vitiligo1.JPG, Non-segmental vitiligo on dark skin, hand facing up File:Eyelid v ...
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Lymphadenitis
Lymphadenopathy or adenopathy is a disease of the lymph nodes, in which they are abnormal in size or consistency. Lymphadenopathy of an inflammatory type (the most common type) is lymphadenitis, producing swollen or enlarged lymph nodes. In clinical practice, the distinction between lymphadenopathy and lymphadenitis is rarely made and the words are usually treated as synonymous. Inflammation of the lymphatic vessels is known as lymphangitis. Infectious lymphadenitis affecting lymph nodes in the neck is often called scrofula. Lymphadenopathy is a common and nonspecific sign. Common causes include infections (from minor causes such as the common cold and post-vaccination swelling to serious ones such as HIV/AIDS), autoimmune diseases, and cancer. Lymphadenopathy is frequently idiopathic and self-limiting. Causes Lymph node enlargement is recognized as a common sign of infectious, autoimmune, or malignant disease. Examples may include: * Reactive: acute infection (''e.g.,'' ba ...
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Suppuration
Pus is an exudate, typically white-yellow, yellow, or yellow-brown, formed at the site of inflammation during bacterial or fungal infection. An accumulation of pus in an enclosed tissue space is known as an abscess, whereas a visible collection of pus within or beneath the epidermis is known as a pustule, pimple or ''spot''. Description Pus consists of a thin, protein-rich fluid (historically known as ''liquor puris'') and dead leukocytes from the body's immune response (mostly neutrophils). During infection, macrophages release cytokines, which trigger neutrophils to seek the site of infection by chemotaxis. There, the neutrophils release granules, which destroy the bacteria. The bacteria resist the immune response by releasing toxins called leukocidins.Madigan, Michael T. and Martin, John M. Brock Biology of Microorganisms 11th ed. Pearson Prentice Hall. US. 2006: 734 As the neutrophils die off from toxins and old age, they are destroyed by macrophages, forming the viscous pu ...
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Plaque (dermatology)
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. Conditions of the human integumentary system constitute a broad spectrum of diseases, also known as dermatoses, as well as many nonpathologic states (like, in certain circumstances, melanonychia and racquet nails). While only a small number of skin diseases account for most visits to the physician, thousands of skin conditions have been described. Classification of these conditions often presents many nosological challenges, since underlying causes and pathogenetics are often not known. Therefore, most current textbooks present a classification based on location (for example, conditions of the mucous membrane), morphology ( chronic blistering conditions), cause (skin conditions result ...
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