Harvard University Medical School
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Harvard University Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with plan ...
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Private University
Private universities and private colleges are institutions of higher education, not operated, owned, or institutionally funded by governments. They may (and often do) receive from governments tax breaks, public student loans, and grant (money), grants. Depending on their location, private universities may be subject to government regulation. Private universities may be contrasted with public university, public universities and national university, national universities. Many private universities are nonprofit organizations. Africa Egypt Egypt currently has 20 public universities (with about two million students) and 23 private universities (60,000 students). Egypt has many private universities, including The American University in Cairo, the German University in Cairo, the British University in Egypt, the Arab Academy for Science, Technology and Maritime Transport, Misr University for Science and Technology, Misr International University, Future University in Egypt and ...
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President And Fellows Of Harvard College
The President and Fellows of Harvard College (also called the Harvard Corporation or just the Corporation) is the smaller and more powerful of Harvard University's two governing boards, and is now the oldest corporation in America. Together with the Board of Overseers, the two boards exercise institutional roles more commonly consolidated into a board of trustees. Although the institution it governs has grown into a university of which Harvard College is one component, the corporation's formal title remains "The President and Fellows of Harvard College". History In 1650, at the request of Harvard President Henry Dunster, the Great and General Court of Massachusetts issued the body's charter, making it now the oldest corporation in the Americas. The subsequent Constitution of the Commonwealth of Massachusetts confirmed that, despite the change in government due to the American Revolution, the corporation would continue to "have, hold, use, exercise and enjoy" its property and le ...
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Poliovirus
A poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species ''Enterovirus C'', in the family of ''Picornaviridae''. There are three poliovirus serotypes: types 1, 2, and 3. Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA (+ssRNA) genome that is about 7500 nucleotides long. The viral particle is about 30 nm in diameter with icosahedral symmetry. Because of its short genome and its simple composition—only RNA and a nonenveloped icosahedral protein coat that encapsulates it—poliovirus is widely regarded as the simplest significant virus. Poliovirus was first isolated in 1909 by Karl Landsteiner and Erwin Popper. The structure of the virus was first elucidated in 1958 using X-ray diffraction by a team at Birkbeck College led by Rosalind Franklin, showing the polio virus to have icosahedral symmetry. In 1981, the poliovirus genome was published by two different teams ...
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Coenzyme A
Coenzyme A (CoA, SHCoA, CoASH) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it (or a thioester) as a substrate. In humans, CoA biosynthesis requires cysteine, pantothenic acid, pantothenate (vitamin B5), and adenosine triphosphate (ATP). In acetyl-CoA, its acetyl form, coenzyme A is a highly versatile molecule, serving metabolic functions in both the Anabolism, anabolic and Catabolism, catabolic pathways. Acetyl-CoA is utilised in the post-translational regulation and allosteric regulation of pyruvate dehydrogenase and carboxylase to maintain and support the partition of Pyruvic acid, pyruvate synthesis and degradation. Discovery of structure Coenzyme A was identified by Fritz Lipmann in 1946, who also later gave it its name. Its structure was determined during the e ...
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Vitamin B12
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, in both fatty acid and amino acid metabolism. It is important in the normal functioning of the nervous system via its role in the synthesis of myelin, and in the circulatory system in the maturation of red blood cells in the bone marrow. Plants do not need cobalamin and carry out the reactions with enzymes that are not dependent on it. Vitamin B12 is the most chemically complex of all vitamins, and for humans, the only vitamin that must be sourced from animal-derived foods or from supplements. Only some archaea and bacteria can synthesize vitamin B12. Most people in developed countries get enough B12 from the consumption of meat or foods with animal sources. Foods containing vitamin B12 include meat, clams, liver, fish, poultry, eggs, and dairy products. Many breakfast cereals are ...
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Diabetes Mellitus
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due to lo ...
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Anesthesia
Anesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), amnesia (loss of memory), and unconsciousness. An individual under the effects of anesthetic drugs is referred to as being anesthetized. Anesthesia enables the painless performance of procedures that would otherwise cause severe or intolerable pain in a non-anesthetized individual, or would otherwise be technically unfeasible. Three broad categories of anesthesia exist: * General anesthesia suppresses central nervous system activity and results in unconsciousness and total lack of sensation, using either injected or inhaled drugs. * Sedation suppresses the central nervous system to a lesser degree, inhibiting both anxiety and creation of long-term memories without resulting in unconsciousness. * Regional and local anesthesia, which blo ...
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Charles William Eliot
Charles William Eliot (March 20, 1834 – August 22, 1926) was an American academic who was president of Harvard University from 1869 to 1909the longest term of any Harvard president. A member of the prominent Eliot family of Boston, he transformed Harvard from a respected provincial college into America's preeminent research university. Theodore Roosevelt called him "the only man in the world I envy." Early life Charles Eliot was a scion of the wealthy Eliot family of Boston. He was the son of politician Samuel Atkins Eliot and his wife Mary (née Lyman) and was the grandchild of banker Samuel Eliot. He was one of five siblings and the only boy. Eliot graduated from Boston Latin School in 1849 and from Harvard University in 1853. He was later made an honorary member of the Hasty Pudding. Although he had high expectations and obvious scientific talents, the first fifteen years of Eliot's career were less than auspicious. He was appointed Tutor in Mathematics at Harvard in t ...
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Holden Chapel
Holden Chapel is a small building in Harvard Yard on the campus of Harvard University. Completed in 1744, it is the third oldest building at Harvard and one of the oldest college buildings in America. Early history In December 1741, Mrs. Samuel Holden, the widow of a former Governor of the Bank of England, offered Harvard a 400 pound sterling donation towards the construction of a chapel on campus, prompted by a suggestion from Thomas Hutchinson. After additional funds were raised, the chapel opened in March 1745. From 1744 to 1772 (except for 1767–68) the chapel housed morning and evening prayers for the Harvard student body, as well as providing space for some secular uses such as lectures. After the 1783 establishment of the Harvard Medical School, the building was used by its founder, John Warren, on a regular basis for 19 years, and intermittently by him and others thereafter until 1825. 20th/21st century In the 1930s, Holden Chapel (and Hollis Hall) were chosen by the ...
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Harvard Hall
Harvard Hall is a Harvard University classroom building in Harvard Yard, Cambridge, Massachusetts. First Harvard Hall The present Harvard Hall replaces an earlier structure of the same name on the same site. The first Harvard Hall was built between 1674 and 1677. It was Harvard College's first brick building and replaced a decaying wooden building located a few hundred feet to the southeast. Samuel Andrew, a local Cambridge merchant and shipwright was the master builder. Present Building The original Harvard Hall burned on January 24, 1764, destroying 4,500 of the College Library's 5,000 books as well as its collection of "philosophical apparatus" (scientific instruments). The Massachusetts General Court, which had been meeting in Harvard Hall to escape a smallpox epidemic in Boston, took responsibility for the fire and funded reconstruction. Thanks to generous donors such as Thomas Hollis V and John Hancock, within two years the new Harvard Hall housed a library larger than ...
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Columbia University Vagelos College Of Physicians And Surgeons
Columbia University Vagelos College of Physicians and Surgeons (VP&S) is the graduate medical school of Columbia University, located at the Columbia University Irving Medical Center in the Washington Heights neighborhood of Manhattan. Founded in 1767 by Samuel Bard as the medical department of King's College (now Columbia University), VP&S was the first medical school in the Thirteen Colonies to award the Doctor of Medicine (MD) degree. Beginning in 1993, VP&S was also the first U.S. medical school to hold a white coat ceremony. According to '' U.S. News & World Report'', VP&S is one of the most selective medical schools in the United States based on average MCAT score, GPA, and acceptance rate. In 2018, 7,537 people applied and 1,007 were interviewed for 140 seats in its entering MD class. The median undergraduate GPA and average MCAT score for successful applicants in 2014 were 3.82 and 36, respectively. Columbia is third for research among American medical schools by ''U.S. ...
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Perelman School Of Medicine At The University Of Pennsylvania
The Perelman School of Medicine, commonly known as Penn Med, is the medical school of the University of Pennsylvania, a private research university in Philadelphia, Pennsylvania. Founded in 1765, the Perelman School of Medicine is the oldest medical school in the United States and is one of the seven Ivy League medical schools. Penn Med is consistently one of the top recipients of NIH research awards and is currently ranked sixth for research among American medical schools by '' U.S. News & World Report''. History The school of medicine was founded by Dr. John Morgan, a graduate of the College of Philadelphia (the precursor of the University of Pennsylvania) and the University of Edinburgh Medical School. After training in Edinburgh and other European cities, Dr. Morgan returned to Philadelphia in 1765. With fellow University of Edinburgh Medical School graduate Dr. William Shippen Jr., Morgan persuaded the college's trustees to found the first medical school in the Original ...
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