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Harvard Six Cities Study
The Harvard "Six Cities" study was a major epidemiological study of over 8,000 adults in six American cities that helped to establish the connection between fine-particulate air pollution (such as diesel engine soot) and reduced life expectancy ("excess mortality"). Widely acknowledged as a landmark piece of public health research, it was initiated by Benjamin G. Ferris, Jr at Harvard School of Public Health and carried out by Harvard's Douglas Dockery, C. Arden Pope of Brigham Young University, Ferris himself, Frank E. Speizer, and four other collaborators, and published in the '' New England Journal of Medicine'' in 1993. Following a lawsuit by The American Lung Association, the study, and its various follow-ups, led to a tightening of pollution standards by the US Environmental Protection Agency. This prompted an intense backlash from industry groups in the late 1990s, culminating in a Supreme Court case, in what ''Science'' magazine termed "the biggest environmental fig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1948 Donora Smog
The 1948 Donora smog killed 20 people and caused respiratory problems for 6,000 of the 14,000 people living in Donora, Pennsylvania, a mill town on the Monongahela River southeast of Pittsburgh. The event is commemorated by the Donora Smog Museum. Sixty years later, the incident was described by ''The New York Times'' as "one of the worst air pollution disasters in the nation's history." Even 10 years after the incident, mortality rates in Donora were significantly higher than those in other communities nearby. Incident The fog started building up in Donora on Wednesday, October 27, 1948. By the following day it was causing coughing and other signs of respiratory distress for many residents of the community in the Monongahela River valley. Many of the illnesses and deaths were initially attributed to asthma. The smog continued until it rained on Sunday, October 31, by which time 20 residents of Donora had died and approximately one third to one half of the town's population of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Watertown, Massachusetts
Watertown is a city in Middlesex County, Massachusetts, and is part of Greater Boston. The population was 35,329 in the 2020 census. Its neighborhoods include Bemis, Coolidge Square, East Watertown, Watertown Square, and the West End. Watertown was one of the first Massachusetts Bay Colony settlements organized by Puritans, Puritan settlers in 1630. The city is home to the Perkins School for the Blind, the Armenian Library and Museum of America, and the historic Watertown Arsenal, which produced military armaments from 1816 through World War II. History Archeological evidence suggests that Watertown was inhabited for thousands of years before European colonization of the Americas, colonization. In the 1600s, two groups of Massachusett, the Pequossette and the Nonantum, had settlements on the banks of the river later called the Charles, and a contemporary source lists "Pigsgusset" as the native name of "Water towne." The Pequossette built a fishing weir to trap herring at the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Topeka, Kansas
Topeka ( ; Kansa language, Kansa: ; iow, Dópikˀe, script=Latn or ) is the Capital (political), capital city of the U.S. state of Kansas and the County seat, seat of Shawnee County, Kansas, Shawnee County. It is along the Kansas River in the central part of Shawnee County, in northeast Kansas, in the Central United States. As of the 2020 United States census, 2020 census, the population of the city was 126,587. The Topeka Topeka, Kansas metropolitan area, metropolitan statistical area, which includes Shawnee, Jackson County, Kansas, Jackson, Jefferson County, Kansas, Jefferson, Osage County, Kansas, Osage, and Wabaunsee County, Kansas, Wabaunsee Counties, had a population of 233,870 in the 2010 United States Census, 2010 census. The name "Topeka" is a Kansa-Osage word that means "place where we dig potatoes", or "a good place to dig potatoes". As a placename, Topeka was first recorded in 1826 as the Kansa name for what is now called the Kansas River. Topeka's founders chose ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Steubenville
Steubenville is a city in and the county seat of Jefferson County, Ohio, United States. Located along the Ohio River 33 miles west of Pittsburgh, it had a population of 18,161 at the 2020 United States Census, 2020 census. The city's name is derived from Fort Steuben, a 1786 fort that sat within the city's current limits and was named for Kingdom of Prussia, Prussian military officer Baron Friedrich Wilhelm von Steuben. It is a principal city of the Weirton–Steubenville metropolitan area, which had a 2020 population of 116,903 residents. Steubenville's nickname is the "City of Murals", after its more than 25 downtown murals. Both the campuses of Franciscan University of Steubenville and Eastern Gateway Community College are in Steubenville. Historically, it was known as the birthplace and home town of Edwin Stanton, United States Secretary of War, Secretary of War during the American Civil War. It is also known as the city where legendary entertainer Dean Martin of the Rat Pack ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
St Louis
St. Louis () is the second-largest city in Missouri, United States. It sits near the confluence of the Mississippi and the Missouri Rivers. In 2020, the city proper had a population of 301,578, while the bi-state metropolitan area, which extends into Illinois, had an estimated population of over 2.8 million, making it the largest metropolitan area in Missouri and the second-largest in Illinois. Before European settlement, the area was a regional center of Native American Mississippian culture. St. Louis was founded on February 14, 1764, by French fur traders Gilbert Antoine de St. Maxent, Pierre Laclède and Auguste Chouteau, who named it for Louis IX of France. In 1764, following France's defeat in the Seven Years' War, the area was ceded to Spain. In 1800, it was retroceded to France, which sold it three years later to the United States as part of the Louisiana Purchase; the city was then the point of embarkation for the Corps of Discovery on the Lewis and Clark Expe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Portage, Wisconsin
Portage is a city in and the county seat of Columbia County, Wisconsin, Columbia County, Wisconsin, United States. The population was 10,581 at the 2020 census making it the largest city in Columbia County. The city is part of the Madison, Wisconsin, metropolitan statistical area, Madison Metropolitan Statistical Area. Portage was named for the Fox-Wisconsin Waterway, a portage between the Fox River (Green Bay tributary), Fox River and the Wisconsin River, which was recognized by Jacques Marquette and Louis Joliet during their discovery of a route to the Mississippi River in 1673. The city's slogan is "Where the North Begins." History The Native Americans in the United States, Native American tribes that once lived here, and later the European traders and settlers, took advantage of the lowlands between the Fox and Wisconsin Rivers as a natural "portage". This is reflected in indigenous names for the town, such as the Menominee name ''Kahkāmohnakaneh'', which means "at the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harriman, Tennessee
Harriman is a city located primarily in Roane County, Tennessee, with a small extension into Morgan County. The population of Harriman was 6,350 at the time of the 2010 census. Harriman is included in the Knoxville, Tennessee Metropolitan Statistical Area. Geography Harriman is located at (35.928585, -84.555700). The city is situated along the physiographic boundary between the Tennessee Valley region and the Cumberland Plateau region, with the Plateau—namely its Walden Ridge escarpment—rising several hundred feet above the city to the west. The Emory River enters the Tennessee Valley just west of Harriman at a pass known as Emory Gap, and forms an oxbow bend that surrounds the original section of Harriman. U.S. Route 27, known as Roane Street in Harriman, runs north-to-south through the city along the base of Walden Ridge. Interstate 40 runs east-to-west through the city's southern section. Harriman's southwestern boundary, which it shares with Rockwood, is loca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Risk Factors
In epidemiology, a risk factor or determinant is a variable associated with an increased risk of disease or infection. Due to a lack of harmonization across disciplines, determinant, in its more widely accepted scientific meaning, is often used as a synonym. The main difference lies in the realm of practice: medicine (clinical practice) versus public health. As an example from clinical practice, low ingestion of dietary sources of vitamin C is a known risk factor for developing scurvy. Specific to public health policy, a determinant is a health risk that is general, abstract, related to inequalities, and difficult for an individual to control. For example, poverty is known to be a determinant of an individual's standard of health. Correlation vs causation Risk factors or determinants are correlational and not necessarily causal, because correlation does not prove causation. For example, being young cannot be said to cause measles, but young people have a higher rate of meas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cohort Study
A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing a cross-section at intervals through time. It is a type of panel study where the individuals in the panel share a common characteristic. Cohort studies represent one of the fundamental designs of epidemiology which are used in research in the fields of medicine, pharmacy, nursing, psychology, social science, and in any field reliant on 'difficult to reach' answers that are based on evidence (statistics). In medicine for instance, while clinical trials are used primarily for assessing the safety of newly developed pharmaceuticals before they are approved for sale, epidemiological analysis on how risk factors affect the incidence of diseases is often used to identify the causes of diseases in the first place, and to help provide pre-clinica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cross-sectional Study
In medical research, social science, and biology, a cross-sectional study (also known as a cross-sectional analysis, transverse study, prevalence study) is a type of observational study that analyzes data from a population, or a representative subset, ''at a specific point in time''—that is, cross-sectional data. In economics, cross-sectional studies typically involve the use of cross-sectional regression, in order to sort out the existence and magnitude of causal effects of one independent variable upon a dependent variable of interest at a given point in time. They differ from time series analysis, in which the behavior of one or more economic aggregates is traced through time. In medical research, cross-sectional studies differ from case-control studies in that they aim to provide data on the entire population under study, whereas case-control studies typically include only individuals who have developed a specific condition and compare them with a matched sample, o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carnegie Mellon University
Carnegie Mellon University (CMU) is a private research university in Pittsburgh, Pennsylvania. One of its predecessors was established in 1900 by Andrew Carnegie as the Carnegie Technical Schools; it became the Carnegie Institute of Technology in 1912 and began granting four-year degrees in the same year. In 1967, the Carnegie Institute of Technology merged with the Mellon Institute of Industrial Research, founded in 1913 by Andrew Mellon and Richard B. Mellon and formerly a part of the University of Pittsburgh. Carnegie Mellon University has operated as a single institution since the merger. The university consists of seven colleges and independent schools: The College of Engineering, College of Fine Arts, Dietrich College of Humanities and Social Sciences, Mellon College of Science, Tepper School of Business, Heinz College of Information Systems and Public Policy, and the School of Computer Science. The university has its main campus located 5 miles (8 km) from Downto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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