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Hardy–Weinberg Principle
In population genetics, the Hardy–Weinberg principle, also known as the Hardy–Weinberg equilibrium, model, theorem, or law, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences. These influences include ''genetic drift'', '' mate choice'', ''assortative mating'', ''natural selection'', ''sexual selection'', ''mutation'', '' gene flow'', ''meiotic drive'', ''genetic hitchhiking'', '' population bottleneck'', '' founder effect,'' ''inbreeding and outbreeding depression''. In the simplest case of a single locus with two alleles denoted ''A'' and ''a'' with frequencies and , respectively, the expected genotype frequencies under random mating are for the AA homozygotes, for the aa homozygotes, and for the heterozygotes. In the absence of selection, mutation, genetic drift, or other forces, allele frequencies ''p'' and ''q'' are constant between generations, so equilibri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homozygote
Zygosity (the noun, zygote, is from the Greek "yoked," from "yoke") () is the degree to which both copies of a chromosome or gene have the same genetic sequence. In other words, it is the degree of similarity of the alleles in an organism. Most eukaryotes have two matching sets of chromosomes; that is, they are diploid. Diploid organisms have the same loci on each of their two sets of homologous chromosomes except that the sequences at these loci may differ between the two chromosomes in a matching pair and that a few chromosomes may be mismatched as part of a chromosomal sex-determination system. If both alleles of a diploid organism are the same, the organism is homozygous at that locus. If they are different, the organism is heterozygous at that locus. If one allele is missing, it is hemizygous, and, if both alleles are missing, it is nullizygous. The DNA sequence of a gene often varies from one individual to another. These gene variants are called alleles. While some gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
X Chromosome
The X chromosome is one of the two sex-determining chromosomes (allosomes) in many organisms, including mammals (the other is the Y chromosome), and is found in both males and females. It is a part of the XY sex-determination system and XO sex-determination system. The X chromosome was named for its unique properties by early researchers, which resulted in the naming of its counterpart Y chromosome, for the next letter in the alphabet, following its subsequent discovery. Discovery It was first noted that the X chromosome was special in 1890 by Hermann Henking in Leipzig. Henking was studying the testicles of ''Pyrrhocoris'' and noticed that one chromosome did not take part in meiosis. Chromosomes are so named because of their ability to take up staining (''chroma'' in Greek means ''color''). Although the X chromosome could be stained just as well as the others, Henking was unsure whether it was a different class of object and consequently named it ''X element'', which later be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heterogametic
Heterogametic sex (digametic sex) refers to the individuals of a species in which the sex chromosomes are not the same. For example, in humans, males with an X and a Y sex chromosome would be referred to as the heterogametic sex, and females having two X sex chromosomes would be referred to as the homogametic sex. This arrangement is known as the XY sex-determination system. However, in birds and some reptiles, males have two Z sex chromosomes and so are the homogametic sex, while females, with one Z and one W chromosome, are the heterogametic sex. Platypus males are heterogametic while females are homogametic. Among the insects, Lepidopterans (butterflies and moths) have heterogametic females, but in ''Drosophila'', males are the heterogametic sex. This arrangement is known as the ZW sex-determination system. Heterogamesis can lead to reduced or absent meiotic recombination between the sex chromosomes, and in some species, this extends to the autosomes, a phenomenon called ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Multinomial Distribution
In probability theory, the multinomial distribution is a generalization of the binomial distribution. For example, it models the probability of counts for each side of a ''k''-sided dice rolled ''n'' times. For ''n'' independent trials each of which leads to a success for exactly one of ''k'' categories, with each category having a given fixed success probability, the multinomial distribution gives the probability of any particular combination of numbers of successes for the various categories. When ''k'' is 2 and ''n'' is 1, the multinomial distribution is the Bernoulli distribution. When ''k'' is 2 and ''n'' is bigger than 1, it is the binomial distribution. When ''k'' is bigger than 2 and ''n'' is 1, it is the categorical distribution. The term "multinoulli" is sometimes used for the categorical distribution to emphasize this four-way relationship (so ''n'' determines the prefix, and ''k'' the suffix). The Bernoulli distribution models the outcome of a single Bernoulli trial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioecious
Dioecy (; ; adj. dioecious , ) is a characteristic of a species, meaning that it has distinct individual organisms (unisexual) that produce male or female gametes, either directly (in animals) or indirectly (in seed plants). Dioecious reproduction is biparental reproduction. Dioecy has costs, since only about half the population directly produces offspring. It is one method for excluding self-fertilization and promoting allogamy (outcrossing), and thus tends to reduce the expression of recessive deleterious mutations present in a population. Plants have several other methods of preventing self-fertilization including, for example, dichogamy, herkogamy, and self-incompatibility. Dioecy is a dimorphic sexual system, alongside gynodioecy and androdioecy. In zoology In zoology, dioecious species may be opposed to hermaphroditic species, meaning that an individual is either male or female, in which case the synonym gonochory is more often used. Most animal species are dioecious (gon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Punnett Square
The Punnett square is a square diagram that is used to predict the genotypes of a particular cross or breeding experiment. It is named after Reginald C. Punnett, who devised the approach in 1905. The diagram is used by biologists to determine the probability of an offspring having a particular genotype. The Punnett square is a tabular summary of possible combinations of maternal alleles with paternal alleles. These tables can be used to examine the genotypical outcome probabilities of the offspring of a single trait (allele), or when crossing multiple traits from the parents. The Punnett square is a visual representation of Mendelian inheritance. It is important to understand the terms "heterozygous", "homozygous", "double heterozygote" (or homozygote), "dominant allele" and "recessive allele" when using the Punnett square method. For multiple traits, using the "forked-line method" is typically much easier than the Punnett square. Phenotypes may be predicted with at least better ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genotype
The genotype of an organism is its complete set of genetic material. Genotype can also be used to refer to the alleles or variants an individual carries in a particular gene or genetic location. The number of alleles an individual can have in a specific gene depends on the number of copies of each chromosome found in that species, also referred to as ploidy. In diploid species like humans, two full sets of chromosomes are present, meaning each individual has two alleles for any given gene. If both alleles are the same, the genotype is referred to as homozygous. If the alleles are different, the genotype is referred to as heterozygous. Genotype contributes to phenotype, the observable traits and characteristics in an individual or organism. The degree to which genotype affects phenotype depends on the trait. For example, the petal color in a pea plant is exclusively determined by genotype. The petals can be purple or white depending on the alleles present in the pea plant. Howev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diploids
Ploidy () is the number of complete sets of chromosomes in a cell, and hence the number of possible alleles for autosomal and pseudoautosomal genes. Sets of chromosomes refer to the number of maternal and paternal chromosome copies, respectively, in each homologous chromosome pair, which chromosomes naturally exist as. Somatic cells, tissues, and individual organisms can be described according to the number of sets of chromosomes present (the "ploidy level"): monoploid (1 set), diploid (2 sets), triploid (3 sets), tetraploid (4 sets), pentaploid (5 sets), hexaploid (6 sets), heptaploid or septaploid (7 sets), etc. The generic term polyploid is often used to describe cells with three or more chromosome sets. Virtually all sexually reproducing organisms are made up of somatic cells that are diploid or greater, but ploidy level may vary widely between different organisms, between different tissues within the same organism, and at different stages in an organism's life cycle. Half ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monoecious
Monoecy (; adj. monoecious ) is a sexual system in seed plants where separate male and female cones or flowers are present on the same plant. It is a monomorphic sexual system alongside gynomonoecy, andromonoecy and trimonoecy. Monoecy is connected to anemophily. It can prevent self-pollination in an individual flower but cannot prevent self-pollination between male and female flowers on the same plant. Monoecy in angiosperms has been of interest for evolutionary biologists since Charles Darwin. Terminology Monoecious comes from the Greek words for one house. History The term monoecy was first introduced in 1735 by Carl Linnaeus. Darwin noted that the flowers of monoecious species sometimes showed traces of the opposite sex function. Monoecious hemp was first reported in 1929. Occurrence Monoecy is most common in temperate climates and is often associated with inefficient pollinators or wind-pollinated plants. It may be beneficial to reducing pollen-stigma interferenc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Population Stratification
Population structure (also called genetic structure and population stratification) is the presence of a systematic difference in allele frequencies between subpopulations. In a randomly mating (or ''panmictic'') population, allele frequencies are expected to be roughly similar between groups. However, mating tends to be non-random to some degree, causing structure to arise. For example, a barrier like a river can separate two groups of the same species and make it difficult for potential mates to cross; if a mutation occurs, over many generations it can spread and become common in one subpopulation while being completely absent in the other. Genetic variants do not necessarily cause observable changes in organisms, but can be correlated by coincidence because of population structure—a variant that is common in a population that has a high rate of disease may erroneously be thought to cause the disease. For this reason, population structure is a common confounding variable in medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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