Haplogroup D (mtDNA)
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Haplogroup D (mtDNA)
In human mitochondrial genetics, Haplogroup D is a human mitochondrial DNA (mtDNA) haplogroup. It is a descendant haplogroup of haplogroup M, thought to have arisen somewhere in Asia, between roughly 60,000 and 35,000 years ago (in the Late Pleistocene, before the Last Glacial Maximum and the settlement of the Americas). estimated at (95% CI) in: In contemporary populations, it is found especially in Central and Northeast Asia. Haplogroup D (more specifically, subclade D4) is one of five main haplogroups found in the indigenous peoples of the Americas, the others being A, B, C, and X. Among the Nepalese population, haplogroup D is the most dominant maternal lineage in Tamang (26.1%) and Magar (24.3%). Subclades There are two principal branches, D4 and D5'6. D1, D2 and D3 are subclades of D4. D4 D1 is a basal branch of D4 that is widespread and diverse in the Americas. Subclades D4b1, D4e1, and D4h are found both in Asia and in the Americas and are thus of special int ...
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Human Mitochondrial DNA (mtDNA) Haplogroup
In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree. Understanding the evolutionary path of the female lineage has helped population geneticists trace the matrilineal inheritance of modern humans back to human origins in Africa and the subsequent spread around the globe. The letter names of the haplogroups (not just mitochondrial DNA haplogroups) run from A to Z. As haplogroups were named in the order of their discovery, the alphabetical ordering does not have any meaning in terms of actual genetic relationships. The hypothetical woman at the root of all these groups (meaning just the mitochondrial DNA haplogroups) is the matrilineal most recent common ancestor (MRCA) for all currently living humans. She is commonly called Mitochondrial Eve. The rate at which mitochondrial DNA mutates is known as the mitochon ...
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