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Haemophilia In European Royalty
Haemophilia figured prominently in the history of European royalty in the 19th and 20th centuries. Queen Victoria of the United Kingdom, through two of her five daughters – Princess Alice and Princess Beatrice – passed the mutation to various royal houses across the continent, including the royal families of Spain, Germany, and Russia. Victoria's youngest son, Prince Leopold, Duke of Albany, also had the disease, though none of her three elder sons did. Tests on the remains of the Romanov imperial family show that the specific form of haemophilia passed down by Queen Victoria was probably the relatively rare haemophilia B."Case Closed: Famous Royals Suffered from Hemophilia".
Michael Price, ScienceNOW, October 9, 2009.
The presence of haemophilia ...
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Haemophilia Of Queen Victoria - Family Tree By Shakko
Haemophilia, or hemophilia (), is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding for a longer time after an injury, easy bruising, and an increased risk of bleeding inside joints or the brain. Those with a mild case of the disease may have symptoms only after an accident or during surgery. Bleeding into a joint can result in permanent damage while bleeding in the brain can result in long term headaches, seizures, or a decreased level of consciousness. There are two main types of haemophilia: haemophilia A, which occurs due to low amounts of clotting factor VIII, and haemophilia B, which occurs due to low levels of clotting factor IX. They are typically inherited from one's parents through an X chromosome carrying a nonfunctional gene. Rarely a new mutation may occur during early development or haemophilia may develop later in life due to antibodies forming against ...
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Mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA replication, DNA or viral replication, mitosis, or meiosis or other types of DNA repair#DNA damage, damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (DNA repair#Translesion synthesis, translesion synthesis). Mutations may also result from Insertion (genetics), insertion or Deletion (genetics), deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce detectable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer ...
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Prince Henry Of Prussia (1862–1929)
en, Albert William Henry , image = Prince Henry of Prussia (1862–1929), brother of Kaiser Wilhelm II.jpg , caption = , birth_date= , birth_place= Berlin, Kingdom of Prussia , spouse = , house = Hohenzollern , father = Frederick III, German Emperor , mother = Victoria, Princess Royal , issue = Prince Waldemar Prince Sigismund Prince Henry , death_date = , death_place = Schloss Hemmelmark, Barkelsby, Schleswig-Holstein, Weimar Republic , burial_date = 24 April 1929 , burial_place = Schloss Hemmelmark, Barkelsby, Schleswig-Holstein, Germany , module = Prince Albert William Henry of Prussia (german: Albert Wilhelm Heinrich; 14 August 1862 – 20 April 1929) was a younger brother of German Emperor William II and a Prince of Prussia. He was also a grandson of Queen Victoria. A career naval officer, he held various commands in the Imperial German Navy and eventually rose to the rank of Grand Admiral and Ge ...
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Princess Charlotte Of Prussia
English: Victoria Elizabeth Augusta Charlotte , father = Frederick III, German Emperor , mother = Victoria, Princess Royal , birth_date = , birth_place = New Palace, Potsdam, Kingdom of Prussia , death_date = , death_place = Baden-Baden, Weimar Republic , burial_date = 7 October 1919 , burial_place = Schloss Altenstein, Thuringia, Germany , religion = Lutheranism Princess Charlotte of Prussia (Viktoria Elisabeth Auguste Charlotte; 24 July 1860 – 1 October 1919) was Duchess of Saxe-Meiningen from 1914 to 1918 as the wife of Bernhard III, the duchy's last ruler. Born at the ''Neues Palais'' in Potsdam, she was the second child and eldest daughter of Prince Frederick of Prussia, a member of the House of Hohenzollern who became Crown Prince of Prussia in 1861 and German Emperor in 1888. Through her mother Victoria, Princess Royal, Charlotte was the eldest granddaughter of the British monarch Queen Victoria and her consort Prince Alber ...
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Wilhelm II Of Germany
, house = Hohenzollern , father = Frederick III, German Emperor , mother = Victoria, Princess Royal , religion = Lutheranism (Prussian United) , signature = Wilhelm II, German Emperor Signature-.svg Wilhelm II (Friedrich Wilhelm Viktor Albert; 27 January 18594 June 1941) was the last German Emperor (german: Kaiser) and King of Prussia, reigning from 15 June 1888 until his abdication on 9 November 1918. Despite strengthening the German Empire's position as a great power by building a powerful navy, his tactless public statements and erratic foreign policy greatly antagonized the international community and are considered by many to be one of the underlying causes of World War I. When the German war effort collapsed after a series of crushing defeats on the Western Front in 1918, he was forced to abdicate, thereby marking the end of the German Empire and the House of Hohenzollern's 300-year reign in Prussia and 500-year reign in Brandenburg. Wilhelm II was the son of ...
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Princess Alice, Countess Of Athlone
Princess Alice, Countess of Athlone (Alice Mary Victoria Augusta Pauline; 25 February 1883 – 3 January 1981) was a member of the British royal family. She is the longest-lived British princess of royal blood, and was the last surviving grandchild of Queen Victoria. Princess Alice was the chatelaine of Rideau Hall in Ottawa from 1940 until 1946, while her husband Alexander Cambridge, 1st Earl of Athlone, served as Governor General of Canada. Early life Princess Alice was born on 25 February 1883 at Windsor Castle, the only daughter of Prince Leopold, Duke of Albany (the youngest of the four sons of Queen Victoria and Albert, Prince Consort) and his wife Princess Helena of Waldeck and Pyrmont. Her younger brother and only sibling, Prince Charles Edward (later Duke of Saxe-Coburg and Gotha), was born on 19 July 1884. She was christened in the Private Chapel of Windsor Castle on 26 March 1883, and named Alice after her late paternal aunt Princess Alice, Grand Duchess of ...
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Prince Arthur, Duke Of Connaught And Strathearn
Prince Arthur, Duke of Connaught and Strathearn (Arthur William Patrick Albert; 1 May 185016 January 1942), was the seventh child and third son of Queen Victoria of the United Kingdom and Prince Albert of Saxe-Coburg and Gotha. He served as Governor General of Canada, the tenth since Canadian Confederation and the only British prince to do so to date. Arthur was educated by private tutors before entering the Royal Military Academy at Woolwich at 16 years old. Upon graduation, he was commissioned as a lieutenant in the British Army, where he served for some 40 years, seeing service in various parts of the British Empire. During this time he was also created a royal duke, becoming Duke of Connaught and Strathearn as well as Earl of Sussex. In 1900 he was appointed as Commander in Chief of the British Army in Ireland, which he regretted; his preference being to join the campaign against the Boers in South Africa. In 1911, he was appointed as Governor General of Canada, replac ...
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Alfred, Duke Of Saxe-Coburg And Gotha
Alfred (Alfred Ernest Albert; 6 August 184430 July 1900) was the sovereign duke of Saxe-Coburg and Gotha from 1893 to 1900. He was the second son and fourth child of Queen Victoria and Prince Albert. He was known as the Duke of Edinburgh from 1866 until he succeeded his paternal uncle Ernest II as the reigning Duke of Saxe-Coburg and Gotha in the German Empire. Early life Prince Alfred was born on 6 August 1844 at Windsor Castle to the reigning British monarch, Queen Victoria, and her husband, Prince Albert, the second son of Ernest I, Duke of Saxe-Coburg and Gotha. Nicknamed Affie, he was second in the line of succession to the British throne behind his elder brother, the Prince of Wales. Alfred was baptised by the Archbishop of Canterbury, William Howley, at the Private Chapel in Windsor Castle on 6 September 1844. His godparents were his mother's first cousin, Prince George of Cambridge (represented by his father, the Duke of Cambridge); his paternal aunt, the Duches ...
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Edward VII
Edward VII (Albert Edward; 9 November 1841 – 6 May 1910) was King of the United Kingdom of Great Britain and Ireland and Emperor of India, from 22 January 1901 until his death in 1910. The second child and eldest son of Queen Victoria and Prince Albert of Saxe-Coburg and Gotha, and nicknamed "Bertie", Edward was related to royalty throughout Europe. He was Prince of Wales and heir apparent to the British throne for almost 60 years. During the long reign of his mother, he was largely excluded from political influence and came to personify the fashionable, leisured elite. He travelled throughout Britain performing ceremonial public duties and represented Britain on visits abroad. His tours of North America in 1860 and of the Indian subcontinent in 1875 proved popular successes, but despite public approval, his reputation as a playboy prince soured his relationship with his mother. As king, Edward played a role in the modernisation of the British Home Fleet and the reorgani ...
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Princess Louise, Duchess Of Argyll
Princess Louise, Duchess of Argyll, (Louisa Caroline Alberta; 18 March 1848 – 3 December 1939) was the sixth child and fourth daughter of Queen Victoria and Prince Albert. In her public life, she was a strong proponent of the arts and higher education and of the feminist cause. Her early life was spent moving among the various royal residences in the company of her family. When her father died in December 1861, the court went into a long period of mourning, to which with time Louise became unsympathetic. She was an able sculptor and artist, and several of her sculptures remain today. She was also a supporter of the feminist movement, corresponding with Josephine Butler, and visiting Elizabeth Garrett. Before her marriage, Louise served as an unofficial secretary to the Queen from 1866 to 1871. The question of Louise's marriage was discussed in the late 1860s. Suitors from the royal houses of Prussia and Denmark were suggested, but Victoria did not want her to marry a fore ...
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Princess Helena Of The United Kingdom
Princess Helena (Helena Augusta Victoria; 25 May 1846 – 9 June 1923), later Princess Christian of Schleswig-Holstein, was the third daughter and fifth child of Queen Victoria and Prince Albert. Helena was educated by private tutors chosen by her father and his close friend and adviser, Baron Stockmar. Her childhood was spent with her parents, travelling between a variety of royal residences in Britain. The intimate atmosphere of the royal court came to an end on 14 December 1861, when her father died and her mother entered a period of intense mourning. Afterwards, in the early 1860s, Helena began a flirtation with Prince Albert's German librarian, Carl Ruland. Although the nature of the relationship is largely unknown, Helena's romantic letters to Ruland survive. After her mother discovered the flirtations, in 1863, she dismissed Ruland, who returned to his native Germany. Three years later, on 5 July 1866, Helena married the impoverished Prince Christian of Schleswig-Hol ...
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Victoria, Princess Royal
Victoria, Princess Royal (Victoria Adelaide Mary Louisa; 21 November 1840 – 5 August 1901) was German Empress and Queen of Prussia as the wife of German Emperor Frederick III. She was the eldest child of Queen Victoria of the United Kingdom and Prince Albert of Saxe-Coburg and Gotha, and was created Princess Royal in 1841. She was the mother of Wilhelm II, German Emperor. Educated by her father in a politically liberal environment, Victoria was married at age 17 to Prince Frederick of Prussia, with whom she had eight children. Victoria shared with Frederick her liberal views and hopes that Prussia and the later German Empire should become a constitutional monarchy, based on the British model. Criticised for this attitude and for her English origins, Victoria suffered ostracism by the House of Hohenzollern, Hohenzollerns and the Berlin court. This isolation increased after the rise to power of Otto von Bismarck, one of her most staunch political opponents, in 1862. Victor ...
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