Hydrangeic Acid
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Hydrangeic Acid
Hydrangeic acid is a stilbenoid found in the leaves of '' Hydrangea macrophylla''.Hydrangeic acid from the processed leaves of Hydrangea macrophylla var. thunbergii as a new type of anti-diabetic compound. Hailong Zhang, Hisashi Matsuda, Chihiro Yamashita, Seikou Nakamura and Masayuki Yoshikawa, European Journal of Pharmacology, Volume 606, Issues 1–3, 15 March 2009, Pages 255–261, Hydrangeic acid is being investigated as a possible antidiabetic drug as it significantly lowered blood glucose, triglyceride and free fatty acid levels in laboratory animals. See also * Lunularic acid Lunularic acid is a dihydrostilbenoid found in the liverwort ''Lunularia cruciata'' and in the roots of ''Hydrangea macrophylla''. A lunularic acid decarboxylase has been detected from the liverwort ''Conocephalum conicum ''Conocephalum conicu ..., the corresponding dihydrostilbenoid also found in ''H. macrophylla'' References Stilbenoids Salicylic acids {{organic-compound-stub ...
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Stilbenoid
Stilbenoids are hydroxylated derivatives of stilbene. They have a C6–C2–C6 structure. In biochemical terms, they belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones. Most stilbenoids are produced by plants, and the only known exception is the antihelminthic and antimicrobial stilbenoid, 2-isopropyl-5- ''E'')-2-phenylvinylenzene-1,3-diol, biosynthesized by the Gram-negative bacterium '' Photorhabdus luminescens.'' Chemistry Stilbenoids are hydroxylated derivatives of stilbene and have a C6–C2–C6 structure. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones. Under UV irradiation, stilbene and its derivatives undergo intramolecular cyclization, called stilbene photocyclization to form dihydrophenanthrenes. Oligomeric forms are known as oligostilbenoids. Types ;Aglycones * Piceatannol in the roots of Norway spruces * Pinosylvin is a fungal toxin protecting wood f ...
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Hydrangea Macrophylla
''Hydrangea macrophylla'' is a species of flowering plant in the family Hydrangeaceae, native to Japan. It is a deciduous shrub growing to tall by broad with large heads of pink or blue flowers in summer and autumn. Common names include bigleaf hydrangea, French hydrangea, lacecap hydrangea, mophead hydrangea, penny mac and hortensia. It is widely cultivated in many parts of the world in many climates. It is not to be confused with '' H. aspera'' 'Macrophylla'. Description The term ''macrophylla'' means large- or long-leaved. The opposite leaves can grow to in length. They are simple, membranous, orbicular to elliptic and acuminate. They are generally serrated. The inflorescence of ''Hydrangea macrophylla'' is a corymb, with all flowers placed in a plane or hemisphere, or even a whole sphere in cultivated forms. Two distinct types of flowers can be identified: central, non-ornamental, pentamerous ones, and peripheral, ornamental, tetramerous ones. The latter have sterile ...
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Antidiabetic Drug
Drugs used in diabetes treat diabetes mellitus by altering the glucose level in the blood. With the exceptions of insulin, most GLP receptor agonists ( liraglutide, exenatide, and others), and pramlintide, all are administered orally and are thus also called oral hypoglycemic agents or oral antihyperglycemic agents. There are different classes of anti-diabetic drugs, and their selection depends on the nature of the diabetes, age and situation of the person, as well as other factors. Diabetes mellitus type 1 is a disease caused by the lack of insulin. Insulin must be used in type 1, which must be injected. Diabetes mellitus type 2 is a disease of insulin resistance by cells. Type 2 diabetes mellitus is the most common type of diabetes. Treatments include agents that (1) increase the amount of insulin secreted by the pancreas, (2) increase the sensitivity of target organs to insulin, (3) decrease the rate at which glucose is absorbed from the gastrointestinal tract, and (4) i ...
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Lunularic Acid
Lunularic acid is a dihydrostilbenoid found in the liverwort ''Lunularia cruciata'' and in the roots of ''Hydrangea macrophylla''. A lunularic acid decarboxylase has been detected from the liverwort ''Conocephalum conicum ''Conocephalum conicum'', also known as the great scented liverwort or snakeskin liverwort, is a liverwort species in the genus ''Conocephalum''. ''C. conicum'' is part of the ''Conocephalum conicum'' complex, which includes several cryptic speci ...''. References Dihydrostilbenoids {{aromatic-stub ...
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Stilbenoids
Stilbenoids are hydroxylated derivatives of stilbene. They have a C6–C2–C6 structure. In biochemical terms, they belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones. Most stilbenoids are produced by plants, and the only known exception is the antihelminthic and antimicrobial stilbenoid, 2-isopropyl-5- ''E'')-2-phenylvinylenzene-1,3-diol, biosynthesized by the Gram-negative bacterium '' Photorhabdus luminescens.'' Chemistry Stilbenoids are hydroxylated derivatives of stilbene and have a C6–C2–C6 structure. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones. Under UV irradiation, stilbene and its derivatives undergo intramolecular cyclization, called stilbene photocyclization to form dihydrophenanthrenes. Oligomeric forms are known as oligostilbenoids. Types ;Aglycones * Piceatannol in the roots of Norway spruces * Pinosylvin is a fungal toxin protecting woo ...
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