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Heuser's Membrane
Heuser's membrane (or the exocoelomic membrane) is a short lived combination of hypoblast cells and extracellular matrix In biology, the extracellular matrix (ECM), also called intercellular matrix, is a three-dimensional network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide s .... At day 9-10 of embryonic development, cells from the hypoblast begin to migrate to the embryonic pole, forming a layer of cells just beneath the cytotrophoblast, called Heuser's membrane. It surrounds the exocoelomic cavity (primary yolk sac), i.e. it lines the inner surface of the cytotrophoblast. At this point, the exocoelomic cavity replaces the blastocyst cavity. At days 11 to 12, there is further delineation of the trophoblastic cells giving rise to a layer of loosely arranged cells that inserts between Heuser's membrane and both syncytiotrophoblast and cytotrophoblast. References Embryology {{ ...
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Extraembryonic Coelom
The gestational sac is the large cavity of fluid surrounding the embryo. During early embryogenesis it consists of the extraembryonic coelom, also called the chorionic cavity. The gestational sac is normally contained within the uterus. It is the only available structure that can be used to determine if an intrauterine pregnancy exists until the embryo can be identified. On obstetric ultrasound, the gestational sac is a dark ( anechoic) space surrounded by a white ( hyperechoic) rim. Structure The gestational sac is spherical in shape, and is usually located in the upper part (fundus) of the uterus. By approximately nine weeks of gestational age, due to folding of the trilaminar germ disc, the amniotic sac expands and occupy the majority of the volume of the gestational sac, eventually reducing the extraembryonic coelom (the gestational sac or the chorionic cavity) to a thin layer between the parietal somatopleuric and visceral splanchnopleuric layer of extraembryonic mesoderm ...
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Hypoblast
In amniote embryology, the hypoblast, is one of two distinct layers arising from the inner cell mass in the mammalian blastocyst, or from the blastodisc in reptiles and birds. The hypoblast gives rise to the yolk sac, which in turn gives rise to the chorion. The hypoblast is a layer of cells in fish and amniote embryos. The hypoblast helps determine the embryo's body axes, and its migration determines the cell movements that accompany the formation of the primitive streak, and helps to orient the embryo, and create bilateral symmetry. The other layer of the inner cell mass, the epiblast, differentiates into the three primary germ layers, ectoderm, mesoderm, and endoderm. Structure The hypoblast lies beneath the epiblast and consists of small cuboidal cells. The hypoblast in fish (but not in birds and mammals) contains the precursors of both the endoderm and mesoderm. In birds and mammals, it contains precursors to the extraembryonic endoderm of the yolk sac. ...
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Extracellular Matrix
In biology, the extracellular matrix (ECM), also called intercellular matrix, is a three-dimensional network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide structural and biochemical support to surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM. The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest. Each type ...
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Yolk Sac
The yolk sac is a membranous sac attached to an embryo, formed by cells of the hypoblast layer of the bilaminar embryonic disc. This is alternatively called the umbilical vesicle by the Terminologia Embryologica (TE), though ''yolk sac'' is far more widely used. In humans, the yolk sac is important in early embryonic blood supply, and much of it is incorporated into the primordial gut during the fourth week of embryonic development. In humans The yolk sac is the first element seen within the gestational sac during pregnancy, usually at 3 days gestation. The yolk sac is situated on the front (ventral) part of the embryo; it is lined by extra-embryonic endoderm, outside of which is a layer of extra-embryonic mesenchyme, derived from the epiblast. Blood is conveyed to the wall of the yolk sac by the primitive aorta and after circulating through a wide-meshed capillary plexus, is returned by the vitelline veins to the tubular heart of the embryo. This constitutes the ...
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