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Hendra Virus
Hendra virus (HeV), scientific name ''Hendra henipavirus'', is a bat-borne virus that is associated with a highly fatal infection in horses and humans. Numerous disease outbreaks in Australia among horses have been caused by Hendra virus. The Hendra virus belongs to the genus ''Henipavirus'', which also contains the Nipah virus, which has also caused disease outbreaks. Pathology Flying foxes experimentally infected with the Hendra virus develop a viraemia and shed the virus in their urine, faeces and saliva for approximately one week. There is no other indication of an illness in them. Symptoms of Hendra virus infection of humans may be respiratory, including hemorrhage and edema of the lungs, or in some cases viral meningitis. In horses, infection usually causes one or more of pulmonary oedema, congestion and neurological signs. Ephrin B2 has been identified as the main receptor for the henipaviruses. Transmission Flying foxes have been identified as the reservoir host of Hend ...
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Transmission Electron Micrograph
Transmission electron microscopy (TEM) is a microscopy technique in which a beam of electrons is transmitted through a specimen to form an image. The specimen is most often an ultrathin section less than 100 nm thick or a suspension on a grid. An image is formed from the interaction of the electrons with the sample as the beam is transmitted through the specimen. The image is then magnified and focused onto an imaging device, such as a fluorescent screen, a layer of photographic film, or a sensor such as a scintillator attached to a charge-coupled device. Transmission electron microscopes are capable of imaging at a significantly higher resolution than light microscopes, owing to the smaller de Broglie wavelength of electrons. This enables the instrument to capture fine detail—even as small as a single column of atoms, which is thousands of times smaller than a resolvable object seen in a light microscope. Transmission electron microscopy is a major analytical method i ...
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Australian Pesticides And Veterinary Medicines Authority
The Australian Pesticides and Veterinary Medicines Authority (APVMA) is the Australian Government statutory agency responsible for the management and regulation of all agricultural and veterinary chemical products in Australia. History The APVMA was established on 15 June 1993 as the National Registration Authority for Agricultural and Veterinary Chemicals, under the ''Agricultural and Veterinary Chemicals (Administration) Act 1992''. Current responsibilities Any agricultural or veterinary product that is manufactured, sold, imported, or used in Australia must first be registered by the APVMA. To be registered, the process may include scientific evaluations of the safety and efficacy of the product. See also *Department of Agriculture and Water Resources The Australian Government Department of Agriculture and Water Resources was a government department that existed between 2015 and 2019, which was responsible for developing and implementing policies and programs that contribu ...
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Index Case
The index case or patient zero is the first documented patient in a disease epidemic within a population, or the first documented patient included in an epidemiological study. It can also refer to the first case of a condition or syndrome (not necessarily contagious) to be described in the medical literature, whether or not the patient is thought to be the first person affected. An index case can achieve the status of a "classic" case study in the literature, as did Phineas Gage, the first known person to exhibit a definitive personality change as a result of a brain injury. Term The index case may or may not indicate the source of the disease, the possible spread, or which reservoir holds the disease in between outbreaks, but may bring awareness of an emerging outbreak. Earlier cases may or may not be found and are labeled primary or coprimary, secondary, tertiary, etc. The term primary case can only apply to infectious diseases that spread from human to human, and refers to t ...
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Queensland
) , nickname = Sunshine State , image_map = Queensland in Australia.svg , map_caption = Location of Queensland in Australia , subdivision_type = Country , subdivision_name = Australia , established_title = Before federation , established_date = Colony of Queensland , established_title2 = Separation from New South Wales , established_date2 = 6 June 1859 , established_title3 = Federation , established_date3 = 1 January 1901 , named_for = Queen Victoria , demonym = , capital = Brisbane , largest_city = capital , coordinates = , admin_center_type = Administration , admin_center = 77 local government areas , leader_title1 = Monarch , leader_name1 = Charles III , leader_title2 = Governor , leader_name2 = Jeannette Young , leader_title3 = Premier , leader_name3 = Annastacia Palaszczuk ( ALP) , legislature = Parliament of Queensland , judiciary = Supreme Court of Queensland , national_representation = Parliament of Australia , national_representation_type ...
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Brisbane
Brisbane ( ) is the capital and most populous city of the states and territories of Australia, Australian state of Queensland, and the list of cities in Australia by population, third-most populous city in Australia and Oceania, with a population of approximately 2.6 million. Brisbane lies at the centre of the South East Queensland metropolitan region, which encompasses a population of around 3.8 million. The Brisbane central business district is situated within a peninsula of the Brisbane River about from its mouth at Moreton Bay, a bay of the Coral Sea. Brisbane is located in the hilly floodplain of the Brisbane River Valley between Moreton Bay and the Taylor Range, Taylor and D'Aguilar Range, D'Aguilar mountain ranges. It sprawls across several local government in Australia, local government areas, most centrally the City of Brisbane, Australia's most populous local government area. The demonym of Brisbane is ''Brisbanite''. The Traditional Owners of the Brisbane a ...
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Hendra, Queensland
Hendra is a suburb of the City of Brisbane, Queensland, Australia. In the , Hendra had a population of 4,625 people. Geography Hendra lies roughly six kilometres north-east of Brisbane central business district. The streets of Hendra are lined with Jacaranda and Royal poinciana Trees. Hendra is roughly bounded by Schultz Canal and the Airport Link motorway in the north, and to the east by the Southern Cross Way and to the south by the Ascot racecourse and the Doomben racecourse. The Doomben railway line enters the suburb from the south-west (Clayfield) and exits to the south ( Ascot). The Hendra railway station services the suburb (). The land use is predominantly residential with an industrial precinct in the north-east of the suburb. History The name ''Hendra'' is derived from the railway station name which was assigned 1882 probably given by Queensland Railway Commissioner Francis Curnow. ''Hendra'' is a traditional Cornish place name meaning an ancient or old ha ...
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Horse
The horse (''Equus ferus caballus'') is a domesticated, one-toed, hoofed mammal. It belongs to the taxonomic family Equidae and is one of two extant subspecies of ''Equus ferus''. The horse has evolved over the past 45 to 55 million years from a small multi-toed creature, ''Eohippus'', into the large, single-toed animal of today. Humans began domesticating horses around 4000 BCE, and their domestication is believed to have been widespread by 3000 BCE. Horses in the subspecies ''caballus'' are domesticated, although some domesticated populations live in the wild as feral horses. These feral populations are not true wild horses, as this term is used to describe horses that have never been domesticated. There is an extensive, specialized vocabulary used to describe equine-related concepts, covering everything from anatomy to life stages, size, colors, markings, breeds, locomotion, and behavior. Horses are adapted to run, allowing them to quickly escape predators, and po ...
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Flying Fox Distribution
Flying may refer to: * Flight, the process of flying * Aviation, the creation and operation of aircraft Music Albums * ''Flying'' (Grammatrain album), 1997 * ''Flying'' (Jonathan Fagerlund album), 2008 * ''Flying'' (UFO album), 1971 * ''Flying'', by Bae Seul-ki * ''Flying'', by Chas & Dave * ''Flying'', by The Hometown Band Songs * "Flying" (Beatles song), 1967 * "Flying" (Bryan Adams song), 2004 * "Flying" (Cast song), 1996 * "Flying" (Chas & Dave song), 1982 * "Flying", by Anathema from ''A Natural Disaster'' * "Flying", by Badfinger from '' Straight Up'' * "Flying", by Cory Marks from the 2022 extended play ''I Rise'' * "Flying", by James Newton Howard from the film ''Peter Pan'' * "Flying", by Living Colour from ''Collideøscope'' * "Flyin'", by Prism from ''See Forever Eyes'' Other uses * ''Flying'' (magazine), a monthly publication * ''Flying'' (film), a 1986 drama film * "Flying" (''The Good Place''), an episode of the American comedy television series * ''Fl ...
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Monoclonal Antibody
A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell Lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell. Monoclonal antibodies can have monovalent affinity, binding only to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different antibody-secreting plasma cell lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one monoclonal antibody to two epitopes. It is possible to produce monoclonal antibodies that specifically bind to virtually any suitable substance; they can then serve to detect or purify it. This capability has become an investigative tool in biochemistry, molecular biology, and medicine. Monoclonal antibodies are being used on a clinical level for both the diagnosis and therapy ...
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Antibodies
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few vari ...
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Glycoproteins
Glycoproteins are proteins which contain oligosaccharide chains covalently attached to amino acid side-chains. The carbohydrate is attached to the protein in a cotranslational or posttranslational modification. This process is known as glycosylation. Secreted extracellular proteins are often glycosylated. In proteins that have segments extending extracellularly, the extracellular segments are also often glycosylated. Glycoproteins are also often important integral membrane proteins, where they play a role in cell–cell interactions. It is important to distinguish endoplasmic reticulum-based glycosylation of the secretory system from reversible cytosolic-nuclear glycosylation. Glycoproteins of the cytosol and nucleus can be modified through the reversible addition of a single GlcNAc residue that is considered reciprocal to phosphorylation and the functions of these are likely to be an additional regulatory mechanism that controls phosphorylation-based signalling. In contrast, ...
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National Institute Of Allergy And Infectious Diseases
The National Institute of Allergy and Infectious Diseases (NIAID, ) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct Basic research, basic and applied research to better understand, treat, and prevent Infectious disease, infectious, Immune disorder, immunologic, and Allergy, allergic diseases. NIAID has on-campus Laboratory, laboratories in Maryland and Hamilton, Montana, and funds research conducted by scientists at institutions in the United States and throughout the world. NIAID also works closely with partners in academia, industry, government, and non-governmental organizations in multifaceted and multidisciplinary efforts to address emerging health challenges such as the pandemic H1N1/09 virus, H1N1/09 pandemic and the COVID-19 pandemic. History NIAID traces its origins to a small laboratory established in 1887 at the Marine ...
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