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Hemiscorpius Lepturus
''Hemiscorpius lepturus'' is a species of scorpion in the family Hemiscorpiidae. It is found in deserts of the Middle East, especially in southern Iraq and Iran. These scorpions have long, thin tails and wide bodies and grow to 8 cm in males and 5.5 cm in females, allowing them to live in tight rock crevices. They are fairly solitary creatures. ''H. lepturus'' has mainly been studied to discover the components and effects of its venom, which is highly lethal and is responsible for most deaths due to scorpion sting in the Iran area. ''H. lepturus'' is the only scorpion not in the family Buthidae that is potentially lethal to humans; the Buthidae family is the largest and most abundant family of scorpions, containing many highly venomous species. Taxonomy ''Hemiscorpius lepturus'' is one of 17 species in the ''Hemiscorpius'' genus, which is the sole genus of the Hemiscorpiidae family. The Hemiscorpiidae family was previously known as Ischnuridae, but was changed due to there bein ...
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Scorpion
Scorpions are predatory arachnids of the order Scorpiones. They have eight legs, and are easily recognized by a pair of grasping pincers and a narrow, segmented tail, often carried in a characteristic forward curve over the back and always ending with a stinger. The evolutionary history of scorpions goes back 435 million years. They mainly live in deserts but have adapted to a wide range of environmental conditions, and can be found on all continents except Antarctica. There are over 2,500 described species, with 22 extant (living) families recognized to date. Their taxonomy is being revised to account for 21st-century genomic studies. Scorpions primarily prey on insects and other invertebrates, but some species hunt vertebrates. They use their pincers to restrain and kill prey, or to prevent their own predation. The venomous sting is used for offense and defense. During courtship, the male and female grasp each other's pincers and dance while he tries to move her onto his s ...
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Trichobothria
Trichobothria (singular trichobothrium) are elongate setae ("hairs") present in arachnids, various orders of insects, and myriapods that function in the detection of airborne vibrations and currents, and electrical charge. In 1883, Friedrich Dahl observed that they were deflected by the sound waves from a violin and labelled them 'hearing hairs'. Morphology Unlike the ordinary setae, which are tapered, the trichobothria have the same gauge throughout their length. They fit into the bottom of a broad and deep cup to which connects a membrane with extreme flexibility which adds an extraordinary mobility to them. The least air vibration is able to get them moving and to excite the small group of sensory cells which ensures their innervation. Distribution Trichobothria are present in most orders of the Arachnida, except in Solifugae, Ricinulei and Opiliones (Grassé, 1949). Although the distribution of trichobothria on the bodies of arachnids is often used by systematists (especial ...
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Lysis
Lysis ( ) is the breaking down of the membrane of a cell, often by viral, enzymic, or osmotic (that is, "lytic" ) mechanisms that compromise its integrity. A fluid containing the contents of lysed cells is called a ''lysate''. In molecular biology, biochemistry, and cell biology laboratories, cell cultures may be subjected to lysis in the process of purifying their components, as in protein purification, DNA extraction, RNA extraction, or in purifying organelles. Many species of bacteria are subject to lysis by the enzyme lysozyme, found in animal saliva, egg white, and other secretions. Phage lytic enzymes (lysins) produced during bacteriophage infection are responsible for the ability of these viruses to lyse bacterial cells. Penicillin and related β-lactam antibiotics cause the death of bacteria through enzyme-mediated lysis that occurs after the drug causes the bacterium to form a defective cell wall. If the cell wall is completely lost and the penicillin was used ...
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Hemitoxin
Hemitoxin (HTX; α-KTx6.15) is a 35-mer basic peptide from the venom of the Iranian scorpion ''Hemiscorpius lepturus'', which reversibly blocks Kv1.1, Kv1.2 and Kv1.3 voltage-gated K+ channels. Sources HTX is a neurotoxin derived from the venom of the scorpion ''Hemiscorpius lepturus'', which is found in the southwest province of Iran, Khuzestan. Hemitoxin constitutes about 0.1% of all venom proteins found in the ''Hemiscorpius lepturus'' venom gland. Chemistry HTX is a peptide composed of 35 amino acids including eight cysteine residues which are cross linked forming four intramolecular cystine amino acids via disulfide bridges. It belongs to subfamily 6 of the α-KTx family of potassium channel scorpion toxins and has the highest sequence similarity with Maurotoxin Maurotoxin (abbreviated MTX) is a peptide toxin from the venom of the Tunisian chactoid scorpion '' Scorpio maurus palmatus'', from which it was first isolated and from which the chemical gets its name. It act ...
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Brown Recluse Spider
The brown recluse (''Loxosceles reclusa''), Sicariidae (formerly placed in a family "Loxoscelidae") is a recluse spider with necrotic venom. Similar to those of other recluse spiders, their bites sometimes require medical attention. The brown recluse is one of three spiders in North America with medically significant venom, the others being the black widow and the Chilean recluse. Brown recluse spiders are usually between , but may grow larger. While typically light to medium brown, they range in color from whitish to dark brown or blackish gray. The cephalothorax and abdomen are not necessarily the same color. These spiders usually have markings on the dorsal side of their cephalothorax, with a black line coming from it that looks like a violin with the neck of the violin pointing to the rear of the spider, resulting in the nicknames fiddleback spider, brown fiddler, or violin spider. Description The violin pattern is not a definitive identifier, as other spiders can have ...
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Sicarius (spider)
''Sicarius'' is a genus of recluse spiders that is potentially medically significant to humans. It is one of three genera in its family, all venomous spiders known for a bite that can induce loxoscelism. They live in deserts and arid regions of the Southern Hemisphere, and females use a mixture of sand and silk when producing egg sacs. The name is Latin for assassin. Description ''Sicarius'' spiders can grow up to long, and have six eyes arranged into three groups of two (known as "dyads"). Physically, they resemble crab spiders and members of the '' Homalonychus'' genus. They lack the characteristic violin-shaped marking of the more well-known members of its family, Sicariidae the recluse spiders. They can live for a very long time without food or water. Some can live for up to fifteen years, making them among the longest-lived spiders, behind the trap-door spiders and tarantulas, many known to live for twenty to thirty years. The oldest recorded spider is Number 16, a tra ...
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Cheiracanthium
''Cheiracanthium'', commonly called ''yellow sac spiders'', is a genus of Araneomorphae, araneomorph spiders in the family Cheiracanthiidae, and was first described by Carl Ludwig Koch in 1839. They are usually pale in colour, and have an spider anatomy#Abdomen, abdomen that can range from yellow to beige. Both sexes range in size from . They are unique among common house spiders because their tarsus (arthropod), tarsi do not point either outward, like members of ''Tegenaria'', or inward, like members of ''Araneus''), making them easier to identify. The name is a reference to the backwardly directed process on the cymbium of the male palp. The species epithet is derived from the Greek grc, wikt:χείρ, χείρ, cheir, meaning "hand", and ''Acanthium'', a genus of thorny-stemmed plants. Venom Though they are beneficial predators in agricultural fields, they are also known to be mildly venomous to humans. Painful bites may be incurred from species such as ''Cheiracanthium pu ...
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Hemolytic–uremic Syndrome
Hemolytic–uremic syndrome (HUS) is a group of blood disorders characterized by low red blood cells, acute kidney failure, and low platelets. Initial symptoms typically include bloody diarrhea, fever, vomiting, and weakness. Kidney problems and low platelets then occur as the diarrhea progresses. Children are more commonly affected, but most children recover without permanent damage to their health, although some children may have serious and sometimes life-threatening complications. Adults, especially the elderly, may present a more complicated presentation. Complications may include neurological problems and heart failure. Most cases occur after infectious diarrhea due to a specific type of '' E. coli'' called O157:H7. Other causes include '' S. pneumoniae'', ''Shigella'', '' Salmonella'', and certain medications. The underlying mechanism typically involves the production of Shiga toxin by the bacteria. Atypical hemolytic uremic syndrome (aHUS) is often due to a genetic mut ...
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Kidney
The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood exits into the paired renal veins. Each kidney is attached to a ureter, a tube that carries excreted urine to the bladder. The kidney participates in the control of the volume of various body fluids, fluid osmolality, acid–base balance, various electrolyte concentrations, and removal of toxins. Filtration occurs in the glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functional unit of the kidney. Each adult human kidney contains around 1 million nephrons, while a mouse kidney contains on ...
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Hemorrhages
Bleeding, hemorrhage, haemorrhage or blood loss, is blood escaping from the circulatory system from damaged blood vessels. Bleeding can occur internally, or externally either through a natural opening such as the mouth, nose, ear, urethra, vagina or anus, or through a puncture in the skin. Hypovolemia is a massive decrease in blood volume, and death by excessive loss of blood is referred to as exsanguination. Typically, a healthy person can endure a loss of 10–15% of the total blood volume without serious medical difficulties (by comparison, blood donation typically takes 8–10% of the donor's blood volume). The stopping or controlling of bleeding is called hemostasis and is an important part of both first aid and surgery. Types * Upper head ** Intracranial hemorrhage – bleeding in the skull. ** Cerebral hemorrhage – a type of intracranial hemorrhage, bleeding within the brain tissue itself. ** Intracerebral hemorrhage – bleeding in the brain caused by the rupture of a ...
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Scorpion Sting
A scorpion sting is an injury caused by the stinger of a scorpion resulting in the medical condition known as scorpionism, which may vary in severity. The anatomical part of the scorpion that delivers the sting is called a "telson". In typical cases, scorpion stings usually result in pain, paresthesia, and variable swelling. In serious cases, scorpion stings may involve the envenomation of humans by toxic scorpions, which may result in extreme pain, serious illness, or even death depending on the toxicity of the venom. Most scorpion stings range in severity from minor swelling to medically significant lesions, with only a few able to cause severe allergic, neurotic or necrotic reactions. However, scorpion stings account for approximately 3,000 deaths a year worldwide. The Brazilian yellow scorpion ('' Tityus serrulatus'') is one species known for being especially dangerous, being responsible for most scorpion sting fatalities in South America. Scorpion stings are seen all over the ...
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