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Guadalupe Sabio
Guadalupe Sabio Buzo (born 4 June 1977) is a Spanish scientist and Professor at the Spanish National Cardiovascular Research Centre, which is part of the Carlos III Health Institute. Her research considers stress-activated kinases and the development of diseases associated with obesity. She was awarded the Princess of Girona Foundation Scientist Prize in 2012 and selected as one of the Top 100 Women Leaders in Spain in 2017. Early life and education Sabio was born in Badajoz in 1977. She attended the Colegio del Santo Ángel and the Institute of San Fernando. She studied veterinary sciences at the University of Extremadura, and graduated in 2000 with an extraordinary award. She has said that she chose to study veterinary science as she liked animals very much, and that this could help her understand the origins of diseases. She moved to the United Kingdom for her doctoral studies, where she joined the University of Dundee as a Medical Research Council European graduate student ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Badajoz
Badajoz (; formerly written ''Badajos'' in English) is the capital of the Province of Badajoz in the autonomous community of Extremadura, Spain. It is situated close to the Portuguese border, on the left bank of the river Guadiana. The population in 2011 was 151,565. Originally a settlement by groups such as the Romans and the Visigoths, its previous name was Civitas Pacensis. Badajoz was conquered by the Moors in the 8th century, and became a Moorish kingdom, the Taifa of Badajoz. After the reconquista, the area was disputed between Spain and Portugal for several centuries with alternating control resulting in several wars including the Spanish War of Succession (1705), the Peninsular War (1808–1811), the Storming of Badajoz (1812), and the Spanish Civil War (1936). Spanish history is largely reflected in the town. Badajoz is the see of the Roman Catholic Archdiocese of Mérida-Badajoz. Prior to the merger of the Diocese of Mérida and the Diocese of Badajoz, Badajoz was the s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
C-Jun N-terminal Kinases
c-Jun N-terminal kinases (JNKs), were originally identified as kinases that bind and phosphorylate c-Jun on Ser-63 and Ser-73 within its transcriptional activation domain. They belong to the mitogen-activated protein kinase family, and are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock. They also play a role in T cell differentiation and the cellular apoptosis pathway. Activation occurs through a dual phosphorylation of threonine (Thr) and tyrosine (Tyr) residues within a Thr-Pro-Tyr motif located in kinase subdomain VIII. Activation is carried out by two MAP kinase kinases, MKK4 and MKK7, and JNK can be inactivated by Ser/Thr and Tyr protein phosphatases. It has been suggested that this signaling pathway contributes to inflammatory responses in mammals and insects. Isoforms The c-Jun N-terminal kinases consist of ten isoforms derived from three genes: JNK1 (four isoforms), JNK2 (four isoforms) and JNK3 (two isofor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spanish Women Scientists
Spanish might refer to: * Items from or related to Spain: **Spaniards are a nation and ethnic group indigenous to Spain **Spanish language, spoken in Spain and many Latin American countries **Spanish cuisine Other places * Spanish, Ontario, Canada * Spanish River (other), the name of several rivers * Spanish Town, Jamaica Other uses * John J. Spanish (1922–2019), American politician * "Spanish" (song), a single by Craig David, 2003 See also * * * Español (other) * Spain (other) * España (other) * Espanola (other) * Hispania, the Roman and Greek name for the Iberian Peninsula * Hispanic, the people, nations, and cultures that have a historical link to Spain * Hispanic (other) * Hispanism * Spain (other) * National and regional identity in Spain * Culture of Spain * Spanish Fort (other) Spanish Fort or Old Spanish Fort may refer to: United States * Spanish Fort, Alabama, a city * Spanish Fort (Colorado ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1977 Births
Events January * January 8 – Three bombs explode in Moscow within 37 minutes, killing seven. The bombings are attributed to an Armenian separatist group. * January 10 – Mount Nyiragongo erupts in eastern Zaire (now the Democratic Republic of the Congo). * January 17 ** 49 marines from the and are killed as a result of a collision in Barcelona harbour, Spain. * January 18 ** Scientists identify a previously unknown bacterium as the cause of the mysterious Legionnaires' disease. ** Australia's worst railway disaster at Granville, a suburb of Sydney, leaves 83 people dead. ** SFR Yugoslavia Prime minister Džemal Bijedić, his wife and 6 others are killed in a plane crash in Bosnia and Herzegovina. * January 19 – An Ejército del Aire CASA C-207C Azor (registration T.7-15) plane crashes into the side of a mountain near Chiva, on approach to Valencia Airport in Spain, killing all 11 people on board. * January 20 – Jimmy Carter is sworn in as the 39th Pres ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AstraZeneca
AstraZeneca plc () is a British-Swedish multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge, England. It has a portfolio of products for major diseases in areas including oncology, cardiovascular, gastrointestinal, infection, neuroscience, respiratory, and inflammation. It has been involved in developing the Oxford–AstraZeneca COVID-19 vaccine. The company was founded in 1999 through the merger of the Swedish Astra AB and the British Zeneca Group (itself formed by the demerger of the pharmaceutical operations of Imperial Chemical Industries in 1993). Since the merger it has been among the world's largest pharmaceutical companies and has made numerous corporate acquisitions, including Cambridge Antibody Technology (in 2006), MedImmune (in 2007), Spirogen (in 2013) and Definiens (by MedImmune in 2014). It has its research and development concentrated in three strategic centres: Cambridge, England; ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
L'Oréal-UNESCO For Women In Science Awards
The L'Oréal-UNESCO For Women in Science Awards, created in 1998, aim to improve the position of women in science by recognizing outstanding women researchers who have contributed to scientific progress. The awards are a result of a partnership between the French cosmetics company L'Oréal and the United Nations Educational, Scientific and Cultural Organization (UNESCO) and carry a grant of $100,000 USD for each laureate. This award is also known as the L'Oréal-Helena Rubinstein Women in Science Awards. Each year an international jury awards five laureates, selecting one from each of the following regions: * Africa and the Middle East. * Asia-Pacific * Europe * Latin America and the Caribbean * North America (since 2000) Eligibility requirements alternate every other year based on scientific discipline with laureates in life sciences recognized in even years and laureates in material sciences and mathematics recognized in odd years. The same partnership awards the UNESCO-L' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Entrega De Los Premios Estrella De La Comunidad De Madrid En El Día Internacional De La Mujer 04
The Rockies Express Pipeline is a long high-pressure natural gas pipeline system from the Rocky Mountains of Colorado Colorado (, other variants) is a state in the Mountain West subregion of the Western United States. It encompasses most of the Southern Rocky Mountains, as well as the northeastern portion of the Colorado Plateau and the western edge of t ... to eastern Ohio. The pipeline system consists of three sections running through eight states. It is one of the largest natural gas pipelines ever built in North America. History The final section of the pipeline was completed on 12 November 2009. Technical description The diameter of long pipeline system varies between , being primarily . The capacity of the pipeline is . It operates at a maximum allowable operating pressure of . The initial cost of the pipeline was around US$5 billion. REX — Entrega (Zone 1) REX — Entrega is the long former Entrega Pipeline between the Meeker, Colorad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Molecular Biology Organization
The European Molecular Biology Organization (EMBO) is a professional, non-profit organization of more than 1,800 life scientists. Its goal is to promote research in life science and enable international exchange between scientists. It co-funds courses, workshops and conferences, publishes five scientific journals and supports individual scientists. The organization was founded in 1964 and is a founding member of the Initiative for Science in Europe. the Director of EMBO is Fiona Watt, a stem cell researcher, professor at King's College London and a group leader at the European Molecular Biology Laboratory. Conferences and journals EMBO funds or co-funds over 90 meetings involving more than 11,000 participants every year. EMBO publishes five peer-reviewed scientific journals: ''The EMBO Journal'', ''EMBO Reports'', ''Molecular Systems Biology'', ''EMBO Molecular Medicine'', and ''Life Science Alliance'', History The European Molecular Biology Organization (EMBO) was launched ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adipose Tissue
Adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes. In addition to adipocytes, adipose tissue contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells such as adipose tissue macrophages. Adipose tissue is derived from preadipocytes. Its main role is to store energy in the form of lipids, although it also cushions and insulates the body. Far from being hormonally inert, adipose tissue has, in recent years, been recognized as a major endocrine organ, as it produces hormones such as leptin, estrogen, resistin, and cytokines (especially TNFα). In obesity, adipose tissue is also implicated in the chronic release of pro-inflammatory markers known as adipokines, which are responsible for the development of metabolic syndrome, a constellation of diseases including, but not limited to, type 2 diabetes, cardiovascular disease and atherosclerosis. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals (signal transduction). The development of therapies with specific molecular or genetic targets, wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Extremadura
University of Extremadura (in es, Universidad de Extremadura) is a Spanish public university in Extremadura (Badajoz and Cáceres). It was founded in 1973 by Decree 991/1973, May 10 ( BOE May 18) of the Ministry of Education and Science of Spain. Currently the University of Extremadura offers 64 Bachelor's Degrees and 32 Master's Degrees in many different fields of knowledge. Together with the University of Cantabria, Castilla-La Mancha, Balearic Islands, La Rioja, Navarra, Oviedo, Zaragoza and the Basque Country, form the Group G9 of Universities (formed by the universities that are alone in their autonomous community). Structure The University of Extremadura is distributed into four different campuses: Badajoz, Cáceres, Mérida and Plasencia. Each campus has different specialities: Badajoz Campus * Faculty of Science (Mathematics, Chemistry, Physics, Chemical Engineering, Biology, Environmental Sciences, Biotechnology, Enology). * School of Industrial Engineerings (I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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