Grand River Aseptic Manufacturing
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Grand River Aseptic Manufacturing
Grand River Aseptic Manufacturing (GRAM) is a clinical and commercial sterile manufacturing contractor to the pharmaceutical industry. It has lyophilization, terminal sterilization, analytical, microbiological testing services. History GRAM was founded in 2010 by Van Andel Institute and Grand Valley State University. In 2017, Arlington Capital Partners, a private equity firm in Washington, D.C. took a majority ownership stake in GRAM. In June 2020, GRAM finished a $60 million expansion to install a 61,500-square-foot fill-finish injectable facility on the same site to triple GRAM's manufacturing footprint to more than 100,000 square feet of production space. In 2020, BARDA and Johnson & Johnson contracted with GRAM to do fill and finish services for vaccines in response to the coronavirus pandemic. In 2022 GRAM was contracted by HHS to fill and finish 2.5 million of the 5.5 million vials of JYNNEOS monkeypox vaccine ordered by the Department of Health and Human Services. ...
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Grand Rapids, MI
Grand Rapids is a city and county seat of Kent County in the U.S. state of Michigan. At the 2020 census, the city had a population of 198,917 which ranks it as the second most-populated city in the state after Detroit. Grand Rapids is the central city of the Grand Rapids metropolitan area, which has a population of 1,087,592 and a combined statistical area population of 1,383,918. Situated along the Grand River approximately east of Lake Michigan, it is the economic and cultural hub of West Michigan, as well as one of the fastest-growing cities in the Midwest. A historic furniture manufacturing center, Grand Rapids is home to five of the world's leading office furniture companies and is nicknamed "Furniture City". Other nicknames include "River City" and more recently, "Beer City" (the latter given by ''USA Today'' and adopted by the city as a brand). The city and surrounding communities are economically diverse, based in the health care, information technology, aut ...
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Freeze-drying
Freeze drying, also known as lyophilization or cryodesiccation, is a low temperature dehydration process that involves freezing the product and lowering pressure, removing the ice by sublimation. This is in contrast to dehydration by most conventional methods that evaporate water using heat. Because of the low temperature used in processing, the rehydrated product retains much of its original qualities. When solid objects like strawberries are freeze dried the original shape of the product is maintained. If the product to be dried is a liquid, as often seen in pharmaceutical applications, the properties of the final product are optimized by the combination of excipients (i.e., inactive ingredients). Primary applications of freeze drying include biological (e.g., bacteria and yeasts), biomedical (e.g., surgical transplants), food processing (e.g., coffee) and preservation. History The Inca were freeze drying potatoes into chuño from the 13th century. The process involved mul ...
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Van Andel Institute
Van Andel Institute (VAI) is a 501(c)(3) nonprofit biomedical research and science education organization in Grand Rapids, Michigan. VAI was founded by Jay and Betty Van Andel in 1996. The institute's research focuses on cancer epigenetics and Parkinson's disease. Its educational efforts support teacher development and science education from early elementary through the doctoral level. David Van Andel, son of Jay and Betty, has served as CEO and chairman of the board since 1996. Research Van Andel Research Institute (VARI) scientists study the epigenetic, genetic, cellular and structural basis of cancer and Parkinson's disease as well as osteoarthritis, neurofibromatosis type 1, Alzheimer's disease, prion diseases, Ewing sarcoma and other conditions. As of 2017, VARI employed 32 faculty and more than 250 people. Center for Epigenetics The Center for Epigenetics was established in 2014 and is led by Peter Jones. Scientists in the Center focus on identifying epigenetic ...
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Grand Valley State University
Grand Valley State University (GVSU, GV, or Grand Valley) is a public university in Allendale, Michigan. It was established in 1960 as Grand Valley State College. Its main campus is situated on approximately west of Grand Rapids. The university also features campuses in Grand Rapids and Holland and regional centers in Battle Creek, Detroit, Muskegon, and Traverse City. GVSU enrolls more than 24,000 students as of fall 2021 from all 83 Michigan counties and dozens of other states and foreign countries. It employs more than 3,000 people, with about 1,780 academic faculty and 1,991 support staff. The university has alumni from 50 U.S. states, Canada, and 25 other countries. GVSU's NCAA Division II sports teams are the Lakers and they compete in the Great Lakes Intercollegiate Athletic Conference (GLIAC) in all 19 intercollegiate varsity sports. They have won 20 NCAA Division II National Championships since 2002 in seven different sports. History Formation, planning and constr ...
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Arlington Capital Partners
Arlington Capital Partners is a Washington, DC based private equity firm focusing on leveraged buyout and recapitalization investments in middle market companies. Started in 1999, the firm manages $4.0 billion of committed capital out of five investment funds. Arlington Capital Partners invests in the aerospace, defense, government services & technology, healthcare services, business services, and software. History The firm was co-founded in 1999 by Raymond W. Smith, Paul G. Stern, Jeffrey H. Freed and Robert I. Knibb. Its first fund closed in 2000 after raising $450 million. The second fund closed in 2006 with $575 million raised, their third fund closed in 2011 with $415.5 million, their fourth fund closed in 2016 with $700 million, and their fifth fund closed in 2019 with $1.7 billion raised. Notable investments Notable investments have included: *Avalign Technologies *Advanced Health *AdVenture Interactive *AEgis *Apogen Technologies *Cadence Aerospace *Cambridge Major La ...
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Washington, D
Washington commonly refers to: * Washington (state), United States * Washington, D.C., the capital of the United States ** A metonym for the federal government of the United States ** Washington metropolitan area, the metropolitan area centered on Washington, D.C. * George Washington (1732–1799), the first president of the United States Washington may also refer to: Places England * Washington, Tyne and Wear, a town in the City of Sunderland metropolitan borough ** Washington Old Hall, ancestral home of the family of George Washington * Washington, West Sussex, a village and civil parish Greenland * Cape Washington, Greenland * Washington Land Philippines *New Washington, Aklan, a municipality *Washington, a barangay in Catarman, Northern Samar *Washington, a barangay in Escalante, Negros Occidental *Washington, a barangay in San Jacinto, Masbate *Washington, a barangay in Surigao City United States * Washington, Wisconsin (other) * Fort Washington (other) ...
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Biomedical Advanced Research And Development Authority
The Biomedical Advanced Research and Development Authority (BARDA) is a U.S. Department of Health and Human Services (HHS) office responsible for the procurement and development of medical countermeasures, principally against bioterrorism, including chemical, biological, radiological and nuclear (CBRN) threats, as well as pandemic influenza and emerging diseases. BARDA was established in 2006 through the Pandemic and All-Hazards Preparedness Act (PAHPA) and reports to the Office of the Assistant Secretary for Preparedness and Response (ASPR). The office manages Project BioShield, which funds the research, development and stockpiling of vaccines and treatments that the government could use during public health emergencies such as chemical, biological, radiological or nuclear (CBRN) attacks. In addition to preparing and maintaining bioterrorism responses and countermeasures, HHS, through the ASPR and BARDA, prepares and maintains an integrated system of medical countermeasu ...
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Johnson & Johnson
Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company is ranked No. 36 on the 2021 Fortune 500 list of the largest United States corporations by total revenue. Johnson & Johnson is one of the List of public corporations by market capitalization, world's most valuable companies, and is one of only two U.S.-based companies that has a prime credit rating of AAA, higher than that of the United States government. Johnson & Johnson is headquartered in New Brunswick, New Jersey, the consumer division being located in Skillman, New Jersey. The corporation includes some 250 subsidiary companies with operations in 60 countries and products sold in over 175 countries. Johnson & Johnson had worldwide sales of $93.8billion during calendar year 2021. Johnson & Johnson's brands include numerous household na ...
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Coronavirus Disease 2019
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, loss of smell, and loss of taste. Symptoms may begin one to fourteen days after exposure to the virus. At least a third of people who are infected do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure, shock, or multiorgan dysfunction). Older people are at a higher risk of developing seve ...
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United States Department Of Health And Human Services
The United States Department of Health and Human Services (HHS) is a cabinet-level executive branch department of the U.S. federal government created to protect the health of all Americans and providing essential human services. Its motto is "Improving the health, safety, and well-being of America". Before the separate federal Department of Education was created in 1979, it was called the Department of Health, Education, and Welfare (HEW). HHS is administered by the Secretary of Health and Human Services, who is appointed by the president with the advice and consent of the United States Senate. The position is currently held by Xavier Becerra. The United States Public Health Service Commissioned Corps, the uniformed service of the PHS, is led by the Surgeon General who is responsible for addressing matters concerning public health as authorized by the secretary or by the assistant secretary for Health in addition to his or her primary mission of administering the Commission ...
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Bausch + Ströbel
Bausch is a German surname. Notable people with the surname include: *Andy Bausch (born 1959), Luxembourgish cinematographer and director *Dotsie Bausch (born 1973), American cyclist *François Bausch (born 1956), Luxembourgish politician, member of the Chamber of Deputies *Frank Bausch (1908–1976), American professional football player *James Bausch (a.k.a. ''Jarring Jim'') (1906–1974), American Olympic decathlete *John Jacob Bausch (1830–1926), German-American optician who co-founded Bausch & Lomb *Ludwig Bausch (1805–1871), German bow (stringed instruments) maker *Pina Bausch (1940–2009), German modern-dance choreographer *Richard Bausch (born 1945), American author *Robert Bausch (1945–2018), American author and professor of English See also *Bausch & Lomb Bausch + Lomb is an eye health products company based in Vaughan, Ontario, Canada. It is one of the world's largest suppliers of contact lenses, lens care products, pharmaceuticals, intraocular lenses, and o ...
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Janssen Pharmaceutica
Janssen Pharmaceuticals is a pharmaceutical company headquartered in Beerse, Belgium, and wholly-owned by Johnson & Johnson. It was founded in 1953 by Paul Janssen. In 1961, Janssen Pharmaceuticals was purchased by New Jersey-based American corporation Johnson & Johnson, and became part of Johnson & Johnson Pharmaceutical Research and Development (J&J PRD), now renamed to Janssen Research and Development (JRD), which conducts research and development activities related to a wide range of human medical disorders, including mental illness, neurological disorders, anesthesia and analgesia, gastrointestinal disorders, fungal infection, HIV/AIDS, allergies and cancer. Janssen and Ortho-McNeil Pharmaceutical have been placed in the Ortho-McNeil-Janssen group within Johnson & Johnson Company. Subsidiaries * Actelion * Cilag AG * Janssen Biotech (formerly ''Centocor'') * Janssen Vaccines (formerly ''Crucell'') * Tibotec * Beijing Dabao Cosmetics Co., Ltd. History The early roots ...
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