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Graham Richards
(William) Graham Richards (born 1 October 1939) is a chemist and Emeritus Fellow of Brasenose College, Oxford. He served as head of the department of chemistry at the University of Oxford from 1997 to 2006. Richards is a pioneer in the field of computer-aided molecular design, in particular its application to the pharmaceuticals industry. He was the founding scientist of Oxford Molecular Ltd., and introduced a novel model for the funding of research at Oxford University, which has been copied elsewhere. Richards was one of the scientific co-founders of Oxford Molecular Limited (OMG). The company developed software for modelling of small molecules and proteins, and drug design. Benefiting from the economic and legal changes, the company was floated on the London Stock Exchange in 1992, making the university £10 million. The company was worth £450 million at its peak but was eventually sold for £70 million. Richards has published more than 300 scientific papers, including 1 ...
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Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ...
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Electronic Spectroscopy
Electronic may refer to: * Electronics, the science of how to control electric energy in semiconductor * ''Electronics'' (magazine), a defunct American trade journal *Electronic storage, the storage of data using an electronic device *Electronic commerce or e-commerce, the trading in products or services using computer networks, such as the Internet *Electronic publishing or e-publishing, the digital publication of books and magazines using computer networks, such as the Internet * Electronic engineering, an electrical engineering discipline Entertainment *Electronic (band), an English alternative dance band ** ''Electronic'' (album), the self-titled debut album by British band Electronic * Electronic music, a music genre *Electronic musical instrument *Electronic game, a game that employs electronics See also *Electronica Electronica is both a broad group of electronic-based music styles intended for listening rather than strictly for dancing and a music scene that started in ...
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Technology Transfer
Technology transfer (TT), also called transfer of technology (TOT), is the process of transferring (disseminating) technology from the person or organization that owns or holds it to another person or organization, in an attempt to transform inventions and scientific outcomes into new products and services that benefit society. Technology transfer is closely related to (and may arguably be considered a subset of) knowledge transfer. A comprehensive definition of technology transfer today includes the notion of collaborative process as it became clear that global challenges could be resolved only through the development of global solutions. Knowledge and technology transfer plays a crucial role in connecting innovation stakeholders and moving inventions from creators to public and private users. Intellectual property (IP) is an important instrument of technology transfer, as it establishes an environment conducive to sharing research results and technologies. Analysis in 2003 showe ...
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Venture Capital
Venture capital (often abbreviated as VC) is a form of private equity financing that is provided by venture capital firms or funds to startups, early-stage, and emerging companies that have been deemed to have high growth potential or which have demonstrated high growth (in terms of number of employees, annual revenue, scale of operations, etc). Venture capital firms or funds invest in these early-stage companies in exchange for equity, or an ownership stake. Venture capitalists take on the risk of financing risky start-ups in the hopes that some of the firms they support will become successful. Because startups face high uncertainty, VC investments have high rates of failure. The start-ups are usually based on an innovative technology or business model and they are usually from high technology industries, such as information technology (IT), clean technology or biotechnology. The typical venture capital investment occurs after an initial "seed funding" round. The first ro ...
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Margaret Thatcher
Margaret Hilda Thatcher, Baroness Thatcher (; 13 October 19258 April 2013) was Prime Minister of the United Kingdom from 1979 to 1990 and Leader of the Conservative Party (UK), Leader of the Conservative Party from 1975 to 1990. She was the first female British prime minister and the longest-serving British prime minister of the 20th century. As prime minister, she implemented economic policies that became known as Thatcherism. A Soviet journalist dubbed her the "Iron Lady", a nickname that became associated with her uncompromising politics and leadership style. Thatcher studied chemistry at Somerville College, Oxford, and worked briefly as a research chemist, before becoming a barrister. She was List of MPs elected in the 1959 United Kingdom general election, elected Member of Parliament for Finchley (UK Parliament constituency), Finchley in 1959 United Kingdom general election, 1959. Edward Heath appointed her Secretary of State for Education and Science in his H ...
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Tony Marchington
Anthony Frank Marchington (2 December 1955 – 16 October 2011) was an English biotechnology entrepreneur and businessman, famous as the co-founder of Oxford Molecular, and the former owner of the famous Class A3 4472 ''Flying Scotsman'' locomotive. Early life Born in Buxton, Derbyshire, he was brought up on the family farm in Buxworth. He passed his motorcycle test at the age of 16, having learned to ride his father's 1914 Bradbury motorcycle and sidecar combination. He attended New Mills Grammar School. He gained his bachelor's degree, master's and D.Phil. at Brasenose College, Oxford. Association with Walter Hooper While at Oxford, Marchington befriended and later lodged with American Walter Hooper, the last personal secretary of the writer C.S. Lewis. Through this relationship Marchington shared a lectern with Hooper in 1975 in North Carolina, co-wrote the script of ''Through Joy and Beyond'' (the 1977 documentary life of Lewis), and created the Lewis bonfire hoax le ...
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Molecular Graphics
Molecular graphics is the discipline and philosophy of studying molecules and their properties through graphical representation. IUPAC limits the definition to representations on a "graphical display device". Ever since Dalton's atoms and Kekulé's benzene, there has been a rich history of hand-drawn atoms and molecules, and these representations have had an important influence on modern molecular graphics. Colour molecular graphics are often used on chemistry journal covers artistically. History Prior to the use of computer graphics in representing molecular structure, Robert Corey and Linus Pauling developed a system for representing atoms or groups of atoms from hard wood on a scale of 1 inch = 1 angstrom connected by a clamping device to maintain the molecular configuration. These early models also established the CPK coloring scheme that is still used today to differentiate the different types of atoms in molecular models (e.g. carbon = black, oxygen = red, nitrogen = blue ...
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Quantum Mechanics
Quantum mechanics is a fundamental theory in physics that provides a description of the physical properties of nature at the scale of atoms and subatomic particles. It is the foundation of all quantum physics including quantum chemistry, quantum field theory, quantum technology, and quantum information science. Classical physics, the collection of theories that existed before the advent of quantum mechanics, describes many aspects of nature at an ordinary (macroscopic) scale, but is not sufficient for describing them at small (atomic and subatomic) scales. Most theories in classical physics can be derived from quantum mechanics as an approximation valid at large (macroscopic) scale. Quantum mechanics differs from classical physics in that energy, momentum, angular momentum, and other quantities of a bound system are restricted to discrete values ( quantization); objects have characteristics of both particles and waves (wave–particle duality); and there are limits to ...
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Ab Initio Quantum Chemistry Methods
''Ab initio'' quantum chemistry methods are computational chemistry methods based on quantum chemistry. The term was first used in quantum chemistry by Robert Parr and coworkers, including David Craig in a semiempirical study on the excited states of benzene. The background is described by Parr. ''Ab initio'' means "from first principles" or "from the beginning", implying that the only inputs into an ''ab initio'' calculation are physical constants. ''Ab initio'' quantum chemistry methods attempt to solve the electronic Schrödinger equation given the positions of the nuclei and the number of electrons in order to yield useful information such as electron densities, energies and other properties of the system. The ability to run these calculations has enabled theoretical chemists to solve a range of problems and their importance is highlighted by the awarding of the Nobel prize to John Pople and Walter Kohn. Accuracy and scaling ''Ab initio'' electronic structure method ...
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Integrals
In mathematics, an integral assigns numbers to functions in a way that describes displacement, area, volume, and other concepts that arise by combining infinitesimal data. The process of finding integrals is called integration. Along with differentiation, integration is a fundamental, essential operation of calculus,Integral calculus is a very well established mathematical discipline for which there are many sources. See and , for example. and serves as a tool to solve problems in mathematics and physics involving the area of an arbitrary shape, the length of a curve, and the volume of a solid, among others. The integrals enumerated here are those termed definite integrals, which can be interpreted as the signed area of the region in the plane that is bounded by the graph of a given function between two points in the real line. Conventionally, areas above the horizontal axis of the plane are positive while areas below are negative. Integrals also refer to the concept of an a ...
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Ferranti Mercury
The Mercury was an early commercial computer from the mid-1950s built by Ferranti. It was the successor to the Ferranti Mark 1, adding a floating point unit for improved performance, and increased reliability by replacing the Williams tube memory with core memory and using more solid-state components. The computer had roughly 2000 vacuum tubes (mostly type CV2179/A2134 pentodes, EL81 pentodes and CV2493/ECC88 double triodes) and 2000 germanium diodes. Nineteen Mercuries were sold before Ferranti moved on to newer designs. Predecessor: Mark I When the Mark I started running in 1951, reliability was poor. The primary concern was the drum memory system, which broke down all the time. Additionally, the machine used 4,200 thermionic valves, mostly EF50 pentodes and diodes that had to be replaced constantly. The Williams tubes, used as random-access memory and registers, were reliable but required constant maintenance. As soon as the system went into operation, teams started looking at s ...
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