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Gradient Enhanced NMR Spectroscopy
Gradient enhanced NMR is a method for obtaining high resolution nuclear magnetic resonance spectra without the need for ''phase cycling''. Gradient methodology is used extensively for two purposes, either rephasing (selection) or dephasing (elimination) of a particular magnetization transfer pathway. It includes the application of magnetic field A magnetic field is a vector field that describes the magnetic influence on moving electric charges, electric currents, and magnetic materials. A moving charge in a magnetic field experiences a force perpendicular to its own velocity and to ... gradient pulses to select specific coherences. By using actively shielded gradients, a gradient pulse is applied during the evolution period of the selected coherence to dephase the transverse magnetization and another gradient pulse refocuses the desired coherences remaining during the acquisition period. Advantages *Significant reduction in measuring time *Reduced T1 artifacts *Eliminatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nuclear Magnetic Resonance
Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus. This process occurs near resonance, when the oscillation frequency matches the intrinsic frequency of the nuclei, which depends on the strength of the static magnetic field, the chemical environment, and the magnetic properties of the isotope involved; in practical applications with static magnetic fields up to ca. 20 tesla, the frequency is similar to VHF and UHF television broadcasts (60–1000 MHz). NMR results from specific magnetic properties of certain atomic nuclei. Nuclear magnetic resonance spectroscopy is widely used to determine the structure of organic molecules in solution and study molecular physics and crystals as well as non-crystalline materials. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pulsed Field Gradient
A pulsed field gradient is a short, timed pulse with spatial-dependent field intensity. Any gradient is identified by four characteristics: axis, strength, shape and duration. Pulsed field gradient (PFG) techniques are key to magnetic resonance imaging, spatially selective spectroscopy and studies of diffusion via diffusion ordered nuclear magnetic resonance spectroscopy Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei. The sample is placed in a magnetic fie ... (DOSY). PFG techniques are widely used as an alternative to phase cycling in modern NMR spectroscopy. Common field gradients in NMR The effect of a uniform magnetic field gradient in the z-direction on spin I, is considered to be a rotation around z-axis by an angle = γIGz; where Gz is the gradient magnitude (along the z-direction) and γI is the gyromagnetic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dephasing
In physics, dephasing is a mechanism that recovers classical behaviour from a quantum system. It refers to the ways in which coherence caused by perturbation decays over time, and the system returns to the state before perturbation. It is an important effect in molecular and atomic spectroscopy, and in the condensed matter physics of mesoscopic devices. The reason can be understood by describing the conduction in metals as a classical phenomenon with quantum effects all embedded into an effective mass that can be computed quantum mechanically, as also happens to resistance that can be seen as a scattering effect of conduction electrons. When the temperature is lowered and the dimensions of the device are meaningfully reduced, this classical behaviour should disappear and the laws of quantum mechanics should govern the behavior of conducting electrons seen as waves that move ballistically inside the conductor without any kind of dissipation. Most of the time this is what one o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magnetic Field
A magnetic field is a vector field that describes the magnetic influence on moving electric charges, electric currents, and magnetic materials. A moving charge in a magnetic field experiences a force perpendicular to its own velocity and to the magnetic field. A permanent magnet's magnetic field pulls on ferromagnetic materials such as iron, and attracts or repels other magnets. In addition, a nonuniform magnetic field exerts minuscule forces on "nonmagnetic" materials by three other magnetic effects: paramagnetism, diamagnetism, and antiferromagnetism, although these forces are usually so small they can only be detected by laboratory equipment. Magnetic fields surround magnetized materials, and are created by electric currents such as those used in electromagnets, and by electric fields varying in time. Since both strength and direction of a magnetic field may vary with location, it is described mathematically by a function assigning a vector to each point of space, cal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coherence (physics)
In physics, two wave sources are coherent if their frequency and waveform are identical. Coherence is an ideal property of waves that enables stationary (i.e., temporally or spatially constant) interference. It contains several distinct concepts, which are limiting cases that never quite occur in reality but allow an understanding of the physics of waves, and has become a very important concept in quantum physics. More generally, coherence describes all properties of the correlation between physical quantities of a single wave, or between several waves or wave packets. Interference is the addition, in the mathematical sense, of wave functions. A single wave can interfere with itself, but this is still an addition of two waves (see Young's slits experiment). Constructive or destructive interference are limit cases, and two waves always interfere, even if the result of the addition is complicated or not remarkable. When interfering, two waves can add together to create a wave of g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magnetization
In classical electromagnetism, magnetization is the vector field that expresses the density of permanent or induced magnetic dipole moments in a magnetic material. Movement within this field is described by direction and is either Axial or Diametric. The origin of the magnetic moments responsible for magnetization can be either microscopic electric currents resulting from the motion of electrons in atoms, or the spin of the electrons or the nuclei. Net magnetization results from the response of a material to an external magnetic field. Paramagnetic materials have a weak induced magnetization in a magnetic field, which disappears when the magnetic field is removed. Ferromagnetic and ferrimagnetic materials have strong magnetization in a magnetic field, and can be ''magnetized'' to have magnetization in the absence of an external field, becoming a permanent magnet. Magnetization is not necessarily uniform within a material, but may vary between different points. Magnetizatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quantum Editing
In physics, a quantum (plural quanta) is the minimum amount of any physical entity (physical property) involved in an interaction. The fundamental notion that a physical property can be "quantized" is referred to as "the hypothesis of quantization". This means that the magnitude of the physical property can take on only discrete values consisting of integer multiples of one quantum. For example, a photon is a single quantum of light (or of any other form of electromagnetic radiation). Similarly, the energy of an electron bound within an atom is quantized and can exist only in certain discrete values. (Atoms and matter in general are stable because electrons can exist only at discrete energy levels within an atom.) Quantization is one of the foundations of the much broader physics of quantum mechanics. Quantization of energy and its influence on how energy and matter interact ( quantum electrodynamics) is part of the fundamental framework for understanding and describing nature. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Shift
In nuclear magnetic resonance (NMR) spectroscopy, the chemical shift is the resonant frequency of an atomic nucleus relative to a standard in a magnetic field. Often the position and number of chemical shifts are diagnostic of the structure of a molecule. Chemical shifts are also used to describe signals in other forms of spectroscopy such as photoemission spectroscopy. Some atomic nuclei possess a magnetic moment ( nuclear spin), which gives rise to different energy levels and resonance frequencies in a magnetic field. The total magnetic field experienced by a nucleus includes local magnetic fields induced by currents of electrons in the molecular orbitals (note that electrons have a magnetic moment themselves). The electron distribution of the same type of nucleus (e.g. ) usually varies according to the local geometry (binding partners, bond lengths, angles between bonds, and so on), and with it the local magnetic field at each nucleus. This is reflected in the spin energy le ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Resonance
Resonance describes the phenomenon of increased amplitude that occurs when the frequency of an applied periodic force (or a Fourier component of it) is equal or close to a natural frequency of the system on which it acts. When an oscillating force is applied at a resonant frequency of a dynamic system, the system will oscillate at a higher amplitude than when the same force is applied at other, non-resonant frequencies. Frequencies at which the response amplitude is a relative maximum are also known as resonant frequencies or resonance frequencies of the system. Small periodic forces that are near a resonant frequency of the system have the ability to produce large amplitude oscillations in the system due to the storage of vibrational energy. Resonance phenomena occur with all types of vibrations or waves: there is mechanical resonance, orbital resonance, acoustic resonance, electromagnetic resonance, nuclear magnetic resonance (NMR), electron spin resonance (ESR) and reso ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
