Gongylonema Neoplasticum
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Gongylonema Neoplasticum
''Gongylonema neoplasticum'' (more famously as ''Spiroptera carcinoma'') is a roundworm parasite of rats. It was discovered by a Danish physician Johannes Fibiger in 1907. Fibiger and Hjalmar Ditlevsen made a formal description in 1914 as ''Spiroptera'' (''Gongylonema'') ''neoplastica''. But Ditlevsen gave the final valid name ''Gongylonema neoplasticum'' in 1918. The nematode is transmitted between rats and cockroaches. When Fibiger discovered the nematode in the stomach of rats, he found that the stomach had tumours. Inspired by the possible link of the nematode and tumour, he performed experiments to induce tumours with nematode infection. He published his experimental success in 1913. The nematode experiment earned Fibiger the 1926 Nobel Prize in Physiology or Medicine, but under controversial circumstances. Moreover, it was later proven that Fibiger came to a wrong conclusion, that the nematode is not carcinogenic. Erling Norrby, who had served as the Permanent Secretary of ...
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Nematode
The nematodes ( or grc-gre, Νηματώδη; la, Nematoda) or roundworms constitute the phylum Nematoda (also called Nemathelminthes), with plant-Parasitism, parasitic nematodes also known as eelworms. They are a diverse animal phylum inhabiting a broad range of environments. Less formally, they are categorized as Helminths, but are taxonomically classified along with Arthropod, arthropods, Tardigrade, tardigrades and other moulting animalia, animals in the clade Ecdysozoa, and unlike platyhelminthe, flatworms, have tubular digestion, digestive systems with openings at both ends. Like tardigrades, they have a reduced number of Hox genes, but their sister phylum Nematomorpha has kept the ancestral protostome Hox genotype, which shows that the reduction has occurred within the nematode phylum. Nematode species can be difficult to distinguish from one another. Consequently, estimates of the number of nematode species described to date vary by author and may change rapidly over ...
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Moulting
In biology, moulting (British English), or molting (American English), also known as sloughing, shedding, or in many invertebrates, ecdysis, is the manner in which an animal routinely casts off a part of its body (often, but not always, an outer layer or covering), either at specific times of the year, or at specific points in its life cycle. In medieval times it was also known as "mewing" (from the French verb "muer", to moult), a term that lives on in the name of Britain's Royal Mews where the King's hawks used to be kept during moulting time before becoming horse stables after Tudor times. Moulting can involve shedding the Epidermis (skin), epidermis (skin), pelage (hair, feathers, fur, wool), or other external layer. In some groups, other body parts may be shed, for example, the entire exoskeleton in arthropods, including the wings in some insects. Examples In birds In birds, moulting is the periodic replacement of feathers by shedding old feathers while producing new o ...
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Discovery And Invention Controversies
Discovery may refer to: * Discovery (observation), observing or finding something unknown * Discovery (fiction), a character's learning something unknown * Discovery (law), a process in courts of law relating to evidence Discovery, The Discovery or Discoveries may also refer to: Film and television * The Discovery (film), ''The Discovery'' (film), a 2017 British-American romantic science fiction film * Discovery Channel, an American TV channel owned by Warner Bros. Discovery * Discovery (Canadian TV series), ''Discovery'' (Canadian TV series), a 1962–1963 Canadian documentary television program * Discovery (Irish TV series), ''Discovery'' (Irish TV series), an Irish documentary television programme * Discovery (UK TV programme), ''Discovery'' (UK TV programme), a British documentary television programme * Discovery (U.S. TV series), ''Discovery'' (U.S. TV series), a 1962–1971 American television news program * ''Star Trek: Discovery'', an American television series ** USS D ...
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Nematodes Described In 1918
The nematodes ( or grc-gre, Νηματώδη; la, Nematoda) or roundworms constitute the phylum Nematoda (also called Nemathelminthes), with plant-parasitic nematodes also known as eelworms. They are a diverse animal phylum inhabiting a broad range of environments. Less formally, they are categorized as Helminths, but are taxonomically classified along with arthropods, tardigrades and other moulting animals in the clade Ecdysozoa, and unlike flatworms, have tubular digestive systems with openings at both ends. Like tardigrades, they have a reduced number of Hox genes, but their sister phylum Nematomorpha has kept the ancestral protostome Hox genotype, which shows that the reduction has occurred within the nematode phylum. Nematode species can be difficult to distinguish from one another. Consequently, estimates of the number of nematode species described to date vary by author and may change rapidly over time. A 2013 survey of animal biodiversity published in the mega journal ...
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Nematodes Described In 1914
The nematodes ( or grc-gre, Νηματώδη; la, Nematoda) or roundworms constitute the phylum Nematoda (also called Nemathelminthes), with plant-parasitic nematodes also known as eelworms. They are a diverse animal phylum inhabiting a broad range of environments. Less formally, they are categorized as Helminths, but are taxonomically classified along with arthropods, tardigrades and other moulting animals in the clade Ecdysozoa, and unlike flatworms, have tubular digestive systems with openings at both ends. Like tardigrades, they have a reduced number of Hox genes, but their sister phylum Nematomorpha has kept the ancestral protostome Hox genotype, which shows that the reduction has occurred within the nematode phylum. Nematode species can be difficult to distinguish from one another. Consequently, estimates of the number of nematode species described to date vary by author and may change rapidly over time. A 2013 survey of animal biodiversity published in the mega journal ...
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Spirurida
Spirurida is an order of spirurian nematodes. Like all nematodes, they have neither a circulatory nor a respiratory system. Some Spirurida, like the genus ''Gongylonema'', can cause disease in humans. One such disease is a skin infection with Spirurida larvae, called "creeping disease". Some species are known as eyeworms and infect the orbital cavity of animal hosts. Systematics The Camallanida are sometimes included herein as a suborder, and the Drilonematida are sometimes placed here as a superfamily. There are doubts about the internal systematics of the Spirurida, and some groups placed herein might belong to other spirurian or even secernentean lineages.ToL (2002) The following superfamilies are at least provisionally placed in the Spirurida: * Acuarioidea * Aproctoidea * Diplotriaenoidea * Filarioidea * Gnathostomatoidea * Habronematoidea * Physalopteroidea * Rictularioidea * Spiruroidea * Thelazioidea Thelazioidea is a superfamily of spirurian nematodes in th ...
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Vitamin A Deficiency
Vitamin A deficiency (VAD) or hypovitaminosis A is a lack of vitamin A in blood and tissues. It is common in poorer countries, especially among children and women of reproductive age, but is rarely seen in more developed countries. Nyctalopia (night blindness) is one of the first signs of VAD, as the vitamin has a major role in phototransduction. Xerophthalmia, keratomalacia, and complete blindness can follow if the deficiency is more severe. Vitamin A deficiency is the world's leading cause of preventable childhood blindness, and is critical to achieving Millennium Development Goal 4 to reduce child mortality. About 250,000 to 500,000 malnourished children in the developing world go blind each year from a deficiency of vitamin A, around half of whom die within a year of becoming blind. The United Nations Special Session on Children in 2002 set a goal of the elimination of VAD by 2010. The prevalence of night blindness due to VAD is also high among pregnant women in many develop ...
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Neoplastic
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potentially ma ...
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Malariotherapy
The malaria therapy (or malaria inoculation, and sometimes malariotherapy) is a medical procedure of treating diseases using artificial injection of malaria parasites. It is a type of pyrotherapy (or pyretotherapy) by which high fever is induced to stop or eliminate symptoms of certain diseases. In malaria therapy, malarial parasites (''Plasmodium'') are specifically used to cause fever, and an elevated body temperature reduces the symptoms of or cure the diseases. As the primary disease is treated, the malaria is then cured using antimalarial drugs. The method was developed by Austrian physician Julius Wagner-Jauregg in 1917 for the treatment of neurosyphilis for which he received the 1927 Nobel Prize in Physiology or Medicine. Background The beneficial effects of infections in mental problems were known in the Ancient world. Hippocrates in the 4th century BCE recorded bacterial infections such as dysentery and dropsy reducing the symptoms of madness; and that malaria (quartan fev ...
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Julius Wagner-Jauregg
Julius Wagner-Jauregg (; 7 March 1857 – 27 September 1940) was an Austrian physician, who won the Nobel Prize in Physiology or Medicine in 1927, and is the first psychiatrist to have done so. His Nobel award was "for his discovery of the therapeutic value of malaria inoculation in the treatment of dementia paralytica". Early life Julius Wagner-Jauregg was born Julius Wagner on 7 March 1857 in Wels, Upper Austria, the son of Adolph Johann Wagner and Ludovika Jauernigg Ranzoni."Physiology or medicine, 1922-1941"
Jan Lindsten. World Scientific, 1999. p. 170. , .
His family name was changed to "Wagner von Jauregg" when his father was given the title of "

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Otto Heinrich Warburg
Otto Heinrich Warburg (, ; 8 October 1883 – 1 August 1970), son of physicist Emil Warburg, was a German physiologist, medical doctor, and Nobel laureate. He served as an officer in the elite Uhlan (cavalry regiment) during the First World War, and was awarded the Iron Cross (1st Class) for bravery. He was the sole recipient of the Nobel Prize in Physiology or Medicine in 1931. In total, he was nominated for the award 47 times over the course of his career. Biography Otto Heinrich Warburg was born in Freiburg im Breisgau in 1883, close to the Swiss border. Otto's mother was the daughter of a Protestant family of bankers and civil servants from Baden. His father, Emil Warburg, had converted to Protestantism as an adult, although Emil's parents were Orthodox Jews. Emil was a member of the illustrious Warburg family of Altona. Emil was also president of the ''Physikalische Reichsanstalt, Wirklicher Geheimer Oberregierungsrat'' (True Senior Privy Counselor). Otto Warburg studied ...
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Carcinoma
Carcinoma is a malignancy that develops from epithelial cells. Specifically, a carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that arises from cells originating in the endodermal, mesodermal or ectodermal germ layer during embryogenesis. Carcinomas occur when the DNA of a cell is damaged or altered and the cell begins to grow uncontrollably and become malignant. It is from the el, καρκίνωμα, translit=karkinoma, lit=sore, ulcer, cancer (itself derived from meaning ''crab''). Classification As of 2004, no simple and comprehensive classification system has been devised and accepted within the scientific community. Traditionally, however, malignancies have generally been classified into various types using a combination of criteria, including: The cell type from which they start; specifically: * Epithelial cells ⇨ carcinoma * Non-hematopoietic mesenchymal cells ⇨ sarcoma * Hematopoietic cells **Bone marrow-de ...
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