Global Buruli Ulcer Initiative
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Global Buruli Ulcer Initiative
The Global Buruli Ulcer Initiative (GBUI) is a World Health Organization (WHO) initiative to coordinate global efforts to control Buruli ulcer, an infectious disease characterized by the development of painless open wounds. It was started in 1998 after a 1997 visit to Côte d'Ivoire by Hiroshi Nakajima, who was then the general director of the WHO, recognizing the lack of research and a growing disease burden. Initially established with funding from the Nippon Foundation, as of 2020 the GBUI involves more than 40 nongovernmental organizations, research institutions, and other foundations. A 2004 WHO resolution "called for increasing surveillance and control, and for intensified research to develop tools to diagnose, treat and prevent" Buruli ulcer. In 2009, a strategy to promote early detection and provide wider access to antibiotics An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting ba ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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Buruli Ulcer
Buruli ulcer () is an infectious disease characterized by the development of painless open wounds. The disease is limited to certain areas of the world, most cases occurring in Sub-Saharan Africa and Australia. The first sign of infection is a small painless nodule or area of swelling, typically on the arms or legs. The nodule grows larger over days to weeks, eventually forming an open ulcer. Deep ulcers can cause scarring of muscles and tendons, resulting in permanent disability. Buruli ulcer is caused by skin infection with bacteria called ''Mycobacterium ulcerans''. The mechanism by which ''M. ulcerans'' is transmitted from the environment to humans is not known, but may involve the bite of an aquatic insect or the infection of open wounds. Once in the skin, ''M. ulcerans'' grows and releases the toxin mycolactone, which blocks the normal function of cells, resulting in tissue death and immune suppression at the site of the ulcer. The World Health Organization (WHO) r ...
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Infectious Disease
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. '' Mycobacterium tuberculosis ...
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Côte D'Ivoire
Ivory Coast, also known as Côte d'Ivoire, officially the Republic of Côte d'Ivoire, is a country on the southern coast of West Africa. Its capital is Yamoussoukro, in the centre of the country, while its largest city and economic centre is the port city of Abidjan. It borders Guinea to the northwest, Liberia to the west, Mali to the northwest, Burkina Faso to the northeast, Ghana to the east, and the Gulf of Guinea (Atlantic Ocean) to the south. Its official language is French, and indigenous languages are also widely used, including Bété, Baoulé, Dioula, Dan, Anyin, and Cebaara Senufo. In total, there are around 78 different languages spoken in Ivory Coast. The country has a religiously diverse population, including numerous followers of Christianity, Islam, and indigenous faiths. Before its colonization by Europeans, Ivory Coast was home to several states, including Gyaaman, the Kong Empire, and Baoulé. The area became a protectorate of France in 1843 and ...
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Hiroshi Nakajima
was a Japanese doctor known chiefly for his tenure as Director-General of the World Health Organization. Early life and education He was born in Chiba, Japan, on 16 May 1928. In 1955 Nakajima received his M.D. from Tokyo Medical University, Japan. He then studied in Paris. At some point after 1967, he obtained a PhD in medical sciences in Japan. Professional life Before 1974: France and Japan From 1956 or 1958 to 1967 Nakajima worked at the French National Institute of Health and Medical Research doing medical and pharmaceutical research. After his stay in France, he returned to Japan and became research director of Nippon Roche, a Japanese subsidiary of Hoffmann-La Roche. Early work at WHO Nakajima joined WHO in 1974 in the position of Scientist, Drug Evaluation and Monitoring. In 1976, he became Chief of the WHO Drug Policies and Management Unit. It was in this position that he played a key role in developing the concept of essential drugs, as Secretary of the first Ex ...
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Nippon Foundation
of Tokyo, Japan, is a private, non-profit grant-making organization. It was established in 1962 by Ryoichi Sasakawa. The foundation's mission is to direct Japanese motorboat racing revenue into philanthropic activities, it uses this money to pursue global maritime development and assistance for humanitarian work, both at home and abroad. In the humanitarian field, it focuses on such fields as social welfare, public health, and education. The foundation has also been criticized for promoting Japanese historical revisionism, particularly in whitewashing Japanese war crimes committed in World War II. Since 2003 the foundation has promoted sign language with the aim of allowing deaf people to fully participate in society, in this way, they created scholarships for deaf people at Gallaudet University and the National Technical Institute for the Deaf (NTID) of USA. The current chairman is Yohei Sasakawa, World Health Organization Goodwill Ambassador for Leprosy Elimination, ...
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Antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and antisep ...
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Public Health
Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the determinants of health of a population and the threats it faces is the basis for public health. The ''public'' can be as small as a handful of people or as large as a village or an entire city; in the case of a pandemic it may encompass several continents. The concept of ''health'' takes into account physical, psychological, and social well-being.What is the WHO definition of health?
from the Preamble to the Constitution of WHO as adopted by the International Health Conference, New York, 19 June - 22 July 1946; signed on ...
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