Giancarlo Rastelli
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Giancarlo Rastelli
Giancarlo Rastelli (1933–1970) was a cardiac surgeon. He was the creator of the Rastelli procedure. He died of cancer at 36 years of age. At the time of his death, he was the head of cardiovascular surgical research at the Mayo Clinic in Rochester, Minnesota. Biography Childhood and private life Rastelli was born in Pescara on 25 June 1933. His father, Vito Rastelli, was a journalist; his mother, Bianchi Luisa, was a primary school teacher. He had a younger sister, Rosangela, who would be an English teacher and social worker. He was interested in medicine from a young age. Rastelli met with Padre Molin Mosè when he was 12 years old. On 10 August 1964, he married Anna Anghileri of Sondrio, who had met while skiing in Bormio. In 1965, Antonella Rastelli was born; she is now a doctor. Entrance into medicine He attended the in Parma and started going to the hospital during his third year; he graduated cum laude in medicine and surgery in 1957, and immediately started work ...
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Servant Of God
"Servant of God" is a title used in the Catholic Church to indicate that an individual is on the first step toward possible canonization as a saint. Terminology The expression "servant of God" appears nine times in the Bible, the first five in the Old Testament, the last four in the New Testament, New. The Hebrew Bible refers to "Moses the servant of Elohim" (עֶֽבֶד הָאֱלֹהִ֛ים ''‘eḇeḏ-hā’ĕlōhîm''; , , , and ). , ). refers to Joshua as ''‘eḇeḏ Yahweh'' (עֶ֣בֶד יְהוָ֑ה). The New Testament also describes Moses in this way in (τοῦ δούλου τοῦ Θεοῦ, ''tou doulou tou Theou''). Paul the Apostle, Paul calls himself "a servant of God" in (δοῦλος Θεοῦ, ''doulos Theou''), while Epistle of James, James calls himself "a servant of God and the Lord Jesus Christ" (θεοῦ καὶ κυρίου Ἰησοῦ χριστοῦ δοῦλος, ''Theou kai Kyriou Iēsou Christou doulos'') in . describes "servants of God" ...
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Coarctation Of The Aorta
Coarctation of the aorta (CoA or CoAo), also called aortic narrowing, is a congenital condition whereby the aorta is narrow, usually in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts. The word ''coarctation'' means "pressing or drawing together; narrowing". Coarctations are most common in the aortic arch. The arch may be small in babies with coarctations. Other heart defects may also occur when coarctation is present, typically occurring on the left side of the heart. When a patient has a coarctation, the left ventricle has to work harder. Since the aorta is narrowed, the left ventricle must generate a much higher pressure than normal in order to force enough blood through the aorta to deliver blood to the lower part of the body. If the narrowing is severe enough, the left ventricle may not be strong enough to push blood through the coarctation, thus resulting in a lack of blood to the lower half of the body. Physiologically its complete form ...
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Atrioventricular Canal
The proper development of the atrioventricular canal into its prospective components (The heart septum and associated valves) to create a clear division between the four compartments of the heart and ensure proper blood movement through the heart, are essential for proper heart function. When this process does not happen correctly, a child will develop atrioventricular canal defect which occurs in 2 out of every 10,000 births. It also has a correlation with Down syndrome because 20% of children with Down syndrome have atrioventricular canal disease as well. This is a very serious condition and surgery is necessary within the first six months of life for a child.Brown, David MD "Atrioventricular Canal Defect" Children's Hospital Boston 20120 http://www.childrenshospital.org/az/Site521/mainpageS521P0.html Half of the children who are untreated with this condition die during their first year due to heart failure or pneumonia. Atrioventricular canal defect is a combination of abnorm ...
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Germ Layer
A germ layer is a primary layer of cells that forms during embryonic development. The three germ layers in vertebrates are particularly pronounced; however, all eumetazoans (animals that are sister taxa to the sponges) produce two or three primary germ layers. Some animals, like cnidarians, produce two germ layers (the ectoderm and endoderm) making them diploblastic. Other animals such as bilaterians produce a third layer (the mesoderm) between these two layers, making them triploblastic. Germ layers eventually give rise to all of an animal’s tissues and organs through the process of organogenesis. History Caspar Friedrich Wolff observed organization of the early embryo in leaf-like layers. In 1817, Heinz Christian Pander discovered three primordial germ layers while studying chick embryos. Between 1850 and 1855, Robert Remak had further refined the germ cell layer (''Keimblatt'') concept, stating that the external, internal and middle layers form respectively the e ...
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Mayo Clinic Proceedings
''Mayo Clinic Proceedings'' is a monthly peer-reviewed medical journal published by Elsevier and sponsored by the Mayo Clinic. It covers the field of general internal medicine. The journal was established in 1926 as the ''Proceedings of the Staff Meetings of the Mayo Clinic'' and obtained its current name in 1964. According to the ''Journal Citation Reports'', the journal has a 2017 impact factor of 7.199, ranking it 11th out of 154 journals in the category "Medicine, General & Internal". The journal started online publishing in 1999. Initially, its website consisted of simple lists of tables of content. In 2012, the current website was established. In addition to the journal content, it contains extra features such as Medical Images, Residents Clinics, Art at Mayo, and Stamp Vignettes on Medical Science, as well as author interviews and monthly issue summaries. Readers can also obtain CME credit. Types of articles published ''Mayo Clinic Proceeding''s publishes the following typ ...
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Ventricle (heart)
A ventricle is one of two large chambers toward the bottom of the heart that collect and expel blood towards the peripheral beds within the body and lungs. The blood pumped by a ventricle is supplied by an atrium, an adjacent chamber in the upper heart that is smaller than a ventricle. Interventricular means between the ventricles (for example the interventricular septum), while intraventricular means within one ventricle (for example an intraventricular block). In a four-chambered heart, such as that in humans, there are two ventricles that operate in a double circulatory system: the right ventricle pumps blood into the pulmonary circulation to the lungs, and the left ventricle pumps blood into the systemic circulation through the aorta. Structure Ventricles have thicker walls than atria and generate higher blood pressures. The physiological load on the ventricles requiring pumping of blood throughout the body and lungs is much greater than the pressure generated by the atria ...
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Atrium (heart)
The atrium ( la, ātrium, , entry hall) is one of two upper chambers in the heart that receives blood from the circulatory system. The blood in the atria is pumped into the heart ventricles through the atrioventricular valves. There are two atria in the human heart – the left atrium receives blood from the pulmonary circulation, and the right atrium receives blood from the venae cavae of the systemic circulation. During the cardiac cycle the atria receive blood while relaxed in diastole, then contract in systole to move blood to the ventricles. Each atrium is roughly cube-shaped except for an ear-shaped projection called an atrial appendage, sometimes known as an auricle. All animals with a closed circulatory system have at least one atrium. The atrium was formerly called the 'auricle'. That term is still used to describe this chamber in some other animals, such as the ''Mollusca''. They have thicker muscular walls than the atria do. Structure Humans have a four-chambered ...
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Endocardial Cushions
Endocardial cushions, or atrioventricular cushions, refer to a subset of cells in the development of the heart that play a vital role in the proper formation of the heart septa. They develop on the atrioventricular canal and conotruncal region of the bulbus cordis. During heart development, the heart starts out as a tube. As heart development continues, this tube undergoes remodeling to eventually form the four-chambered heart. The endocardial cushions are a subset of cells found in the developing heart tube that will give rise to the heart's primitive valves and septa, critical to the proper formation of a four-chambered heart. Development The endocardial cushions are thought to arise from a subset of endothelial cells that undergo epithelial-mesenchymal transition, a process whereby these cells break cell-to-cell contacts and migrate into the cardiac jelly (towards the interior of the heart tube). These migrated cells form the "swellings" called the endocardial cushions seen in ...
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Mitral
The mitral valve (), also known as the bicuspid valve or left atrioventricular valve, is one of the four heart valves. It has two cusps or flaps and lies between the left atrium and the left ventricle of the heart. The heart valves are all one-way valves allowing blood flow in just one direction. The mitral valve and the tricuspid valve are known as the atrioventricular valves because they lie between the atria and the ventricles. In normal conditions, blood flows through an open mitral valve during diastole with contraction of the left atrium, and the mitral valve closes during systole with contraction of the left ventricle. The valve opens and closes because of pressure differences, opening when there is greater pressure in the left atrium than ventricle and closing when there is greater pressure in the left ventricle than atrium. In abnormal conditions, blood may flow backward through the valve ( mitral regurgitation) or the mitral valve may be narrowed (mitral stenosis). Rhe ...
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Tricuspid
The tricuspid valve, or right atrioventricular valve, is on the right dorsal side of the mammalian heart, at the superior portion of the right ventricle. The function of the valve is to allow blood to flow from the right atrium to the right ventricle during diastole, and to close to prevent backflow ( regurgitation) from the right ventricle into the right atrium during right ventricular contraction (systole). Structure The tricuspid valve usually has three cusps or leaflets, named the anterior, posterior, and septal cusps. Each leaflet is connected via chordae tendineae to the anterior, posterior, and septal papillary muscles of the right ventricle, respectively. Tricuspid valves may also occur with two or four leaflets; the number may change over a lifetime. Function The tricuspid valve functions as a one-way valve that closes during ventricular systole to prevent regurgitation of blood from the right ventricle back into the right atrium. It opens during ventricular diastole ...
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Atrioventricular Valves
A heart valve is a one-way valve that allows blood to flow in one direction through the chambers of the heart. Four valves are usually present in a mammalian heart and together they determine the pathway of blood flow through the heart. A heart valve opens or closes according to differential blood pressure on each side. The four valves in the mammalian heart are two atrioventricular valves separating the upper atria from the lower ventricles – the mitral valve in the left heart, and the tricuspid valve in the right heart. The other two valves are at the entrance to the arteries leaving the heart these are the semilunar valves – the aortic valve at the aorta, and the pulmonary valve at the pulmonary artery. The heart also has a coronary sinus valve, and an inferior vena cava valve, not discussed here. Structure The heart valves and the chambers are lined with endocardium. Heart valves separate the atria from the ventricles, or the ventricles from a blood vessel. Heart ...
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Crux Cardis
Crux () is a constellation of the southern sky that is centred on four bright stars in a cross-shaped asterism commonly known as the Southern Cross. It lies on the southern end of the Milky Way's visible band. The name ''Crux'' is Latin for cross. Even though it is the smallest of all 88 modern constellations, Crux is among the most easily distinguished as its four main stars each have an apparent visual magnitude brighter than +2.8. It has attained a high level of cultural significance in many Southern Hemisphere states and nations. Blue-white α Crucis (Acrux) is the most southerly member of the constellation and, at magnitude 0.8, the brightest. The three other stars of the cross appear clockwise and in order of lessening magnitude: β Crucis (Mimosa), γ Crucis (Gacrux), and δ Crucis (Imai). ε Crucis (Ginan) also lies within the cross asterism. Many of these brighter stars are members of the Scorpius–Centaurus association, a large but loose group of hot blue-white sta ...
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