German Acupuncture Trials
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German Acupuncture Trials
The German acupuncture trials (german: GERAC-Studien) were a series of nationwide acupuncture trials set up in 2001 and published in 2006 on behalf of several German statutory health insurance companies because of a dispute as to the usefulness of acupuncture. They consisted of one observational study on acupuncture side effects, and four randomized controlled trials (RCTs) investigating acupuncture treatment for low back pain, knee osteoarthritis, migraine prophylaxis, and tension-type headache. The trials are considered to be one of the largest clinical studies in the field of acupuncture. As a result of the GERAC trials, the German Federal Joint Committee ruled in April 2006 that the costs of acupuncture treatment for chronic back pain and knee osteoarthritis would be covered by public health insurers in Germany, though no coverage was offered for headache or migraine. However, because of the outcome of these trials, in the case of the other conditions, insurance corpor ...
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Deutsches Ärzteblatt
The ''Deutsches Ärzteblatt'' is a weekly German-language medical magazine published in Germany. Profile ''Deutsches Ärzteblatt'' is published by the Deutscher Ärzte Verlag, which is co-owned by the German Medical Association (''Bundesärztekammer'') and the National Association of Statutory Health Insurance Physicians (''Kassenärztliche Bundesvereinigung''). It is the official journal of these two bodies, distributed to all physicians in Germany. It is published in three editions - Medical Practice Edition, Clinical Edition, and Other.''Deutsches Ärzteblatt''Excerpt from Rate Card 55/ref> The magazine is based in Cologne. ''Deutsches Ärzteblatt International'', launched in 2008, is published weekly in German and English, and is a peer-reviewed open access medical journal indexed in MEDLINE, PubMed and other citation indices.aerzteblatt.deAbout Us/ref> In 2013, ''Deutsches Ärzteblatt'' had a circulation of 370,000 copies. See also * List of magazines in Germany The follo ...
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Efficacy
Efficacy is the ability to perform a task to a satisfactory or expected degree. The word comes from the same roots as ''effectiveness'', and it has often been used synonymously, although in pharmacology a pragmatic clinical trial#Efficacy versus effectiveness, distinction is now often made between efficacy and effectiveness. The word ''efficacy'' is used in pharmacology and medicine to refer both to the maximum response achievable from a pharmaceutical drug in research settings, and to the capacity for sufficient therapeutic effect or beneficial change in clinical settings. Pharmacology In pharmacology, efficacy () is the maximum response achievable from an applied or dosed agent, for instance, a small molecule drug. Intrinsic activity is a relative term for a drug's efficacy relative to a drug with the highest observed efficacy. It is a purely descriptive term that has little or no mechanistic interpretation. In order for a drug to have an effect, it needs to bind to its t ...
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Placebo
A placebo ( ) is a substance or treatment which is designed to have no therapeutic value. Common placebos include inert tablets (like sugar pills), inert injections (like Saline (medicine), saline), sham surgery, and other procedures. In general, placebos can affect how patients perceive their condition and encourage the body's chemical processes for relieving pain and a few other symptoms, but have no impact on the disease itself. Improvements that patients experience after being treated with a placebo can also be due to unrelated factors, such as regression to the mean (a statistical effect where an unusually high or low measurement is likely to be followed by a less extreme one). The use of placebos in clinical medicine raises ethical concerns, especially if they are disguised as an active treatment, as this introduces dishonesty into the doctor–patient relationship and bypasses informed consent. While it was once assumed that this deception was necessary for placebos to have ...
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NHS Choices
The National Health Service (NHS) is the publicly funded healthcare system in England, and one of the four National Health Service systems in the United Kingdom. It is the second largest single-payer healthcare system in the world after the Brazilian Sistema Único de Saúde. Primarily funded by the government from general taxation (plus a small amount from National Insurance contributions), and overseen by the Department of Health and Social Care, the NHS provides healthcare to all legal English residents and residents from other regions of the UK, with most services free at the point of use for most people. The NHS also conducts research through the National Institute for Health and Care Research (NIHR). Free healthcare at the point of use comes from the core principles at the founding of the National Health Service. The 1942 Beveridge cross-party report established the principles of the NHS which was implemented by the Labour government in 1948. Labour's Minister for H ...
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University Of Exeter
The University of Exeter is a public university , public research university in Exeter, Devon, England, United Kingdom. Its predecessor institutions, St Luke's College, Exeter School of Science, Exeter School of Art, and the Camborne School of Mines were established in 1838, 1855, 1863, and 1888 respectively. These institutions later formed the University of Exeter after receiving its royal charter in 1955. In Post-nominal letters, post-nominals, the University of Exeter is abbreviated as ''Exon.'' (from the Latin ''Exoniensis''), and is the suffix given to Honorary Degree, honorary and academic degrees from the university. The university has four campuses: Streatham Campus, Streatham and St. Luke's Campus, St Luke's (both of which are in Exeter); and Truro and Penryn Campus, Penryn (both of which are in Cornwall). The university is primarily located in the city of Exeter, Devon, where it is the principal higher education institution. Streatham is the largest campus containing many ...
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Edzard Ernst
Edzard Ernst (born 30 January 1948) is a retired British-German academic physician and researcher specializing in the study of complementary and alternative medicine. He was Professor of Complementary Medicine at the University of Exeter, allegedly the world's first such academic position in complementary and alternative medicine. Ernst served as chairman of Physical Medicine and Rehabilitation (PMR) at the University of Vienna, but left this position in 1993 to set up the department of Complementary Medicine at the University of Exeter in England. He became director of complementary medicine of the Peninsula Medical School (PMS) in 2002. Ernst was the first occupant of the Maurice Laing, Laing chair in Complementary Medicine, retiring in 2011. He was born and trained in Germany, where he began his medical career at a homeopathic hospital in Munich, and since 1999 has been a British citizen. Ernst is the founder of two medical journals: ''Focus on Alternative and Complementary Th ...
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Deutsche Medizinische Wochenschrift
The ''Deutsche Medizinische Wochenschrift'' (''German Medical Weekly'') (''DMW'') is a German medical journal established in 1875 by Paul Börner. In the 1980s it was ranked 10th in the world in terms of its impact factor, but in the succeeding two decades the journal lost much of its preeminence due largely to the declining importance of the German language in medical publications and the appearance of a large number of new medical journals in the English language. It is currently published by Georg Thieme Verlag and is an official publication of the Deutsche Gesellschaft für Innere Medizin and the Gesellschaft Deutscher Naturforscher und Ärzte. The editor in chief is Martin Middeke. According to the Journal Citation Reports, its 2008 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given ...
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Adverse Events
An adverse event (AE) is any untoward medical occurrence in a patient or clinical investigation subject administered a pharmaceutical product and which does not necessarily have a causal relationship with this treatment. An adverse event can therefore be any unfavourable and unintended sign (including an abnormal laboratory finding), symptom, or disease temporally associated with the use of a medicinal (investigational) product, whether or not related to the medicinal (investigational) product. AEs in patients participating in clinical trials must be reported to the study sponsor and if required could be reported to the local ethics committee. Adverse events categorized as "serious" (results in death, illness requiring hospitalization, events deemed life-threatening, results in persistent or significant incapacity, a congenital anomaly, birth defect or medically important condition) must be reported to the regulatory authorities immediately, whereas non-serious adverse events are ...
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Knee Osteoarthritis
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone which affects 1 in 7 adults in the United States. It is believed to be the fourth leading cause of disability in the world. The most common symptoms are joint pain and stiffness. Usually the symptoms progress slowly over years. Initially they may occur only after exercise but can become constant over time. Other symptoms may include joint swelling, decreased range of motion, and, when the back is affected, weakness or numbness of the arms and legs. The most commonly involved joints are the two near the ends of the fingers and the joint at the base of the thumbs; the knee and hip joints; and the joints of the neck and lower back. Joints on one side of the body are often more affected than those on the other. The symptoms can interfere with work and normal daily activities. Unlike some other types of arthritis, only the joints, not internal organs, are af ...
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University Of Mainz
The Johannes Gutenberg University Mainz (german: Johannes Gutenberg-Universität Mainz) is a public research university in Mainz, Rhineland Palatinate, Germany, named after the printer Johannes Gutenberg since 1946. With approximately 32,000 students (2018) in about 100 schools and clinics, it is among the largest universities in Germany. Starting on 1 January 2005 the university was reorganized into 11 faculties of study. The university is a member of the German U15, a coalition of fifteen major research-intensive and leading medical universities in Germany. The Johannes Gutenberg University is considered one of the most prestigious universities in Germany. The university is part of the IT-Cluster Rhine-Main-Neckar. The Johannes Gutenberg University Mainz, the Goethe University Frankfurt and the Technische Universität Darmstadt together form the Rhine-Main-Universities (RMU). History The first University of Mainz goes back to the Archbishop of Mainz, Prince-elector and ...
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University Of Marburg
The Philipps University of Marburg (german: Philipps-Universität Marburg) was founded in 1527 by Philip I, Landgrave of Hesse, which makes it one of Germany's oldest universities and the oldest still operating Protestant university in the world. It is now a public university of the state of Hesse, without religious affiliation. The University of Marburg has about 23,500 students and 7,500 employees and is located in Marburg, a town of 76,000 inhabitants, with university buildings dotted in or around the town centre. About 14 per cent of the students are international, the highest percentage in Hesse. It offers an International summer university programme and offers student exchanges through the Erasmus programme. History In 1609, the University of Marburg established the world's first professorship in chemistry. In 2012 it opened the first German interactive chemistry museum, called '. Its experimental course programme is aimed at encouraging young people to pursue careers in ...
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