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George Larrick
George P. Larrick (November 19, 1901August 11, 1968) was Commissioner of the U.S. Food and Drug Administration (FDA) from 19541965. Early life George P. Larrick was born on November 19, 1901, in Springfield, Ohio. He worked his way through two years at Wittenberg College from 19191921, and then took a pre-medical course at Ohio State University from 19211923. In 1923, he accepted a "temporary job" as a food and drug inspector in Cincinnati, Ohio. Fascinated with the work, he abandoned his medical aspirations, and successfully passed the competitive Civil Service examination for a permanent appointment. By 1930, he had been appointed senior food and drug inspector. In 1937, he was responsible for dispatching very nearly the entire field force of the FDA to track down remnants of the poisonous Elixir Sulfanilamide which killed 109 people, and highlighted the need for pre-market testing of new drugs. Larrick was also responsible for assembling an exhibit, dubbed by reporters, " ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Commissioner Of Food And Drugs
The United States Commissioner of Food and Drugs is the head of the Food and Drug Administration (FDA), an agency of the United States Department of Health and Human Services. The commissioner is appointed by the president of the United States and must be confirmed by the Senate. The commissioner reports to the Secretary of Health and Human Services. Due to frequent controversies involving the FDA, appointments are not always prompt and the agency is often headed by an acting commissioner. For example, Andrew von Eschenbach's appointment was held up by senators who objected to the FDA's refusal to allow emergency contraception to be sold over the counter. The commissioner has frequently been a physician, but this is not a requirement for the post. Commissioners rarely come from a food-related background. List of commissioners ''Unnumbered, colored rows indicate acting commissioners.'' See also * Regulation of therapeutic goods References {{FDA commissioners Commissioners ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food, Drug, And Cosmetic Act
The United States Federal Food, Drug, and Cosmetic Act (abbreviated as FFDCA, FDCA, or FD&C) is a set of laws passed by the United States Congress in 1938 giving authority to the U.S. Food and Drug Administration (FDA) to oversee the safety of food, drugs, medical devices, and cosmetics. A principal author of this law was Royal S. Copeland, a three-term U.S. senator from New York. In 1968, the Electronic Product Radiation Control provisions were added to the FD&C. Also in that year the FDA formed the Drug Efficacy Study Implementation (DESI) to incorporate into FD&C regulations the recommendations from a National Academy of Sciences investigation of effectiveness of previously marketed drugs. The act has been amended many times, most recently to add requirements about bioterrorism preparations. The introduction of this act was influenced by the death of more than 100 patients due to elixir sulfanilamide, a sulfanilamide medication where the toxic solvent diethylene glycol was us ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pan American Health Organization
The Pan American Health Organization (PAHO) is an international public health agency working to improve the health and living standards of the people of the Americas. It is part of the United Nations system, serving as the Regional Office for the Americas of the World Health Organization and as the health organization of the Organization of American States, Inter-American System. It is known in Latin America as the OPS or OPAS ( es, Organización Panamericana de la Salud; pt, Organização Pan-Americana da Saúde). Description PAHO has scientific and technical expertise at its headquarters, in its 27 country offices, and its three Pan American centers, all working with the countries of the americas in dealing with priority health issues. The health authorities of PAHO's Member States set PAHO's technical and administrative policies through its governing bodies. The PAHO Member States include all 35 countries in the Americas; Puerto Rico is an associate member. France, the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John W
John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second Epistle of John, often shortened to 2 John * Third Epistle of John, often shortened to 3 John People * John the Baptist (died c. AD 30), regarded as a prophet and the forerunner of Jesus Christ * John the Apostle (lived c. AD 30), one of the twelve apostles of Jesus * John the Evangelist, assigned author of the Fourth Gospel, once identified with the Apostle * John of Patmos, also known as John the Divine or John the Revelator, the author of the Book of Revelation, once identified with the Apostle * John the Presbyter, a figure either identified with or distinguished from the Apostle, the Evangelist and John of Patmos Other people with the given name Religious figures * John, father of Andrew the Apostle and Saint Peter * Pope Jo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kefauver Harris Amendment
Carey Estes Kefauver (; July 26, 1903 – August 10, 1963) was an American politician from Tennessee. A member of the Democratic Party, he served in the U.S. House of Representatives from 1939 to 1949 and in the Senate from 1949 until his death in 1963. After leading a much-publicized investigation into organized crime in the early 1950s, he twice sought his party's nomination for President of the United States. In 1956, he was selected by the Democratic National Convention to be the running mate of presidential nominee Adlai Stevenson. He still held his U.S. Senate seat after the Stevenson–Kefauver ticket lost to the Eisenhower–Nixon ticket. Kefauver was named chair of the U.S. Senate Antitrust and Monopoly Subcommittee in 1957 and served as its chairman until his death. Early life Carey Estes Kefauver was born in Madisonville, Tennessee, the son of local hardware merchant Robert Cooke Kefauver and his wife Phredonia Bradford Estes. Kefauver was introduced to poli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drugs In Pregnancy
Drugs and medications should be avoided while pregnant. Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. Tobacco, alcohol, marijuana, and illicit drug use while pregnant may be dangerous for the unborn baby and may lead to severe health problems and/or birth defects. Even small amounts of alcohol, tobacco, and marijuana have not been proven to be safe when taken while pregnant. In some cases, for example, if the mother has epilepsy or diabetes, the risk of stopping a medication may be worse than risks associated with taking the medication while pregnant. The mother's healthcare professional will help make these decisions about the safest way to protect the health of both the mother and unborn child. In addition to medications and substances, some dietary supplements are important for a healthy pregnancy, however, others may cause harm to the unborn child. The Food and Drug Administration (FDA) in the United S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thalidomide
Thalidomide, sold under the brand names Contergan and Thalomid among others, is a medication used to treat a number of cancers (including multiple myeloma), graft-versus-host disease, and a number of skin conditions including complications of leprosy. While it has been used in a number of HIV-associated conditions, such use is associated with increased levels of the virus. It is taken by mouth. Common side effects include sleepiness, rash, and dizziness. Severe side effects include tumor lysis syndrome, blood clots, and peripheral neuropathy. Use in pregnancy may harm the fetus, including resulting in malformation of the limbs. In males who are taking the medication, contraception is essential if a partner could become pregnant. It is an immunomodulatory medication and works by a number of mechanisms, including stimulating T cells and decreasing TNF-α production. Thalidomide was first marketed in 1957 in West Germany, where it was available over the counter. When first r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Krebiozen
Krebiozen (aka Carcalon, creatine, substance X, or drug X) is a disproven cancer treatment that is made available as an alternative cancer treatment. While the substance has been marketed as a cure for cancer, originally sold for thousands of dollars per dose in the 1950s and early '60s, Krebiozen is not known to possess any therapeutic value. Attempts to analyze its composition have shown that Krebiozen consists only of the amino acid creatine dissolved in mineral oil, and some samples sold as Krebiozen consist solely of mineral oil with no other discernible ingredients. The American Cancer Society states: "Available scientific evidence does not support claims that Krebiozen is effective in treating cancer or any other disease." According to the U.S. Food and Drug Administration (FDA), Krebiozen has been linked to several dangerous side effects. History and evaluation Krebiozen was initially promoted by Stevan Durovic, a Yugoslavian physician who claimed that the substance c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hoxsey Therapy
Hoxsey Therapy or Hoxsey Method is an alternative medicine, alternative medical treatment promoted as a cure for cancer. The treatment consists of a caustic herbal paste for external cancers or an herbal mixture for "internal" cancers, combined with laxatives, douches, dietary supplement, vitamin supplements, and dietary changes. Reviews by major medical bodies, including the U.S. Food and Drug Administration (FDA), the National Cancer Institute, the American Cancer Society, M. D. Anderson Cancer Center, and Memorial Sloan-Kettering Cancer Center, have found no evidence that Hoxsey Therapy is an effective treatment for cancer. The sale or marketing of the Hoxsey Method was banned in the United States by the FDA on September 21, 1960 as a "worthless and discredited" remedy and a form of quackery. Currently, the Hoxsey Method is primarily marketed by the Bio-Medical Center in Tijuana, Mexico. Hoxsey Therapy is also marketed over the Internet; in June 2008, the FDA National Health Frau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3-Amino-1,2,4-triazole
3-Amino-1,2,4-triazole (3-AT) is a heterocyclic organic compound that consists of a 1,2,4-triazole substituted with an amino group. 3-AT is a competitive inhibitor of the product of the HIS3 gene, imidazoleglycerol-phosphate dehydratase. Imidazoleglycerol-phosphate dehydratase is an enzyme catalyzing the sixth step of histidine production. 3-AT is also a nonselective systemic triazole herbicide used on nonfood croplands to control annual grasses and broadleaf and aquatic weeds. It is not used on food crops because of its carcinogenic properties. As an herbicide, it is known as ''aminotriazole'', ''amitrole'' or ''amitrol''. Amitrol was included in a biocide ban proposed by the Swedish Chemicals Agency and approved by the European Parliament on January 13, 2009. Applications in microbiology By applying 3-AT to a yeast cell culture which is dependent upon a plasmid containing HIS3 to produce histidine (i.e. its own HIS3 analogue is not present or nonfunctional), an increased lev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States House Committee On Appropriations
The United States House Committee on Appropriations is a committee of the United States House of Representatives that is responsible for passing appropriation bills along with its Senate counterpart. The bills passed by the Appropriations Committee regulate expenditures of money by the government of the United States. As such, it is one of the most powerful committees, and its members are seen as influential. History The constitutional basis for the Appropriations Committee comes from Article one, Section nine, Clause seven of the U.S. Constitution, which says: :No money shall be drawn from the treasury, but in consequence of appropriations made by law; and a regular statement and account of receipts and expenditures of all public money shall be published from time to time. This clearly delegated the power of appropriating money to Congress, but was vague beyond that. Originally, the power of appropriating was taken by the Committee on Ways and Means, but the United States C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John E
John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second Epistle of John, often shortened to 2 John * Third Epistle of John, often shortened to 3 John People * John the Baptist (died c. AD 30), regarded as a prophet and the forerunner of Jesus Christ * John the Apostle (lived c. AD 30), one of the twelve apostles of Jesus * John the Evangelist, assigned author of the Fourth Gospel, once identified with the Apostle * John of Patmos, also known as John the Divine or John the Revelator, the author of the Book of Revelation, once identified with the Apostle * John the Presbyter, a figure either identified with or distinguished from the Apostle, the Evangelist and John of Patmos Other people with the given name Religious figures * John, father of Andrew the Apostle and Saint Peter * Pope J ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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