George H. Hitchings
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George H. Hitchings
George Herbert Hitchings (April 18, 1905 – February 27, 1998) was an American medical doctor who shared the 1988 Nobel Prize in Physiology or Medicine with Sir James Black and Gertrude Elion "for their discoveries of important principles for drug treatment", Hitchings specifically for his work on chemotherapy. Education and early life Hitchings was born in Hoquiam, Washington, in 1905, and grew up there, in Berkeley, California, San Diego, Bellingham, Washington, and Seattle. He graduated from Seattle's Franklin High School, where he was salutatorian, in 1923, and from there went to the University of Washington, from which he graduated with a degree in chemistry ''cum laude'' in 1927, after having been elected to Phi Beta Kappa as a junior the year before. That summer, he worked at the university's Puget Sound Biological Station at Friday Harbor on San Juan Islandbr> and received a master's degree the next year for his thesis based on that work. From the University of Wash ...
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Hoquiam, Washington
Hoquiam ( ) is a city in Grays Harbor County, Washington, United States. It borders the city of Aberdeen at Myrtle Street, with Hoquiam to the west. The two cities share a common economic history in lumbering and exporting, but Hoquiam has maintained its independent identity. It shares a long rivalry with its more populated neighbor, especially in high school sports. Hoquiam (Ho'-kwee-um, or Ho-kwim, to natives) was incorporated on May 21, 1890. Its name comes from a Native-American word meaning "hungry for wood", from the great amount of driftwood at the mouth of the Hoquiam River. The population was 8,776 at the 2020 census. History One of the first logging operations in Hoquiam was established by Ed Campbell in 1872.Van Syckle, Ed. A Brief Historical Sketch of Grays Harbor Washington. Chambers of Commerce of Hoquiam and Aberdeen, Washington, 1942. About 10 years later, Captain Asa M. Simpson, a Pacific Coast mariner and businessman in the lumber industry from San Francisco, ...
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Seattle
Seattle ( ) is a seaport city on the West Coast of the United States. It is the seat of King County, Washington. With a 2020 population of 737,015, it is the largest city in both the state of Washington and the Pacific Northwest region of North America. The Seattle metropolitan area's population is 4.02 million, making it the 15th-largest in the United States. Its growth rate of 21.1% between 2010 and 2020 makes it one of the nation's fastest-growing large cities. Seattle is situated on an isthmus between Puget Sound (an inlet of the Pacific Ocean) and Lake Washington. It is the northernmost major city in the United States, located about south of the Canadian border. A major gateway for trade with East Asia, Seattle is the fourth-largest port in North America in terms of container handling . The Seattle area was inhabited by Native Americans for at least 4,000 years before the first permanent European settlers. Arthur A. Denny and his group of travelers, subsequ ...
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Folic Acid
Folate, also known as vitamin B9 and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as a dietary supplement and in food fortification as it is more stable during processing and storage. Folate is required for the body to make DNA and RNA and metabolise amino acids necessary for cell division. As humans cannot make folate, it is required in the diet, making it an essential nutrient. It occurs naturally in many foods. The recommended adult daily intake of folate in the U.S. is 400 micrograms from foods or dietary supplements. Folate in the form of folic acid is used to treat anemia caused by folate deficiency. Folic acid is also used as a supplement by women during pregnancy to reduce the risk of neural tube defects (NTDs) in the baby. Low levels in early pregnancy are believed to be the cause of more than half of babies born with NTDs. More than 80 countries use either mandatory or voluntary fortification ...
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Leukemia
Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ''leukemia cells''. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown. A combination of genetic factors and environmental (non-inherited) factors are believed to play a role. Risk factors include smoking, ionizing radiation, petrochemicals (such as benzene), prior chemotherapy, and Down syndrome. People with a family history of leukemia are also at higher risk. There are four main types of leukemia— acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chronic ...
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Tuckahoe (village), New York
Tuckahoe is a administrative divisions of New York#Village, village in Westchester County, New York, Westchester County, New York (state), New York, United States. One-and-a-half miles long and three-fourths of a mile wide, with the Bronx River serving as its western boundary, the Village of Tuckahoe is approximately sixteen miles north of midtown Manhattan in Southern Westchester County. As of the 2010 census, the village's population was 6,486. The village can be reached by the Metro-North railroad system. The Tuckahoe (Metro-North station), Tuckahoe and Crestwood (Metro-North station), Crestwood stations are 32 minutes and 34 minutes from New York City's Grand Central Terminal, respectively. History Industry and growth The name “Tuckahoe," meaning “it is globular," was a general term used by the Native Americans of the region when describing various bulbous roots which were used as food. Throughout the 1700s and 1800s, Tuckahoe was a rural, minor community which was ...
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Alpha Chi Sigma
Alpha Chi Sigma () is a professional fraternity specializing in the fields of the chemical sciences. It has both collegiate and professional chapters throughout the United States consisting of both men and women and numbering more than 70,000 members. The fraternity aims to bring together students and professionals pursuing a wide variety of chemistry-related careers. History Founding The Alpha Chi Sigma fraternity was organized at the University of Wisconsin–Madison by a group of undergraduates who were fellow students in chemistry at that time. Later documents set the date of founding as December 11, 1902. The original founders were: * Raymond Tracy Conger * Harold Everett Eggers * Joseph Gerard Holty * Alfred Emil Kundert * Joseph Howard Mathews * Edward Gustav Mattke * Bart Eldred McCormick * Frank Joseph Petura * James Chisholm Silverthorn Coat of arms The seven symbols that stretch the length of the coat of arms are the "seven metals of the Ancients": gold, silver ...
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Doctor Of Philosophy
A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is an earned research degree, those studying for a PhD are required to produce original research that expands the boundaries of knowledge, normally in the form of a dissertation, and defend their work before a panel of other experts in the field. The completion of a PhD is often a requirement for employment as a university professor, researcher, or scientist in many fields. Individuals who have earned a Doctor of Philosophy degree may, in many jurisdictions, use the title ''Doctor'' (often abbreviated "Dr" or "Dr.") with their name, although the proper etiquette associated with this usage may also be subject to the professional ethics of their own scholarly field, culture, or society. Those who teach at universities or work in academic, edu ...
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San Juan Island
San Juan Island is the second-largest and most populous of the San Juan Islands in northwestern Washington, United States. It has a land area of 142.59 km2 (55.053 sq mi) and a population of 6,822 as of the 2000 census. Washington State Ferries serves Friday Harbor, which is San Juan Island's major population center, the San Juan County seat, and the only incorporated town in the islands. History The name "San Juan" originates from the 1791 expedition of Francisco de Eliza, who named the archipelago ''Isla y Archipiélago de San Juan'' to honor his patron sponsor, Juan Vicente de Güemes Padilla Horcasitas y Aguayo, 2nd Count of Revillagigedo. One of the officers under Eliza's command, Gonzalo López de Haro, was the first European to discover San Juan Island. During the Wilkes Expedition, American explorer Charles Wilkes renamed the island ''Rodgers Island''; the Spanish name remained on British nautical charts and over time became the island's official name. The ...
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Friday Harbor, Washington
Friday Harbor is a town in San Juan County, Washington, United States. The population was 2,162 at 2010 census. Located on San Juan Island, Friday Harbor is the major commercial center of the San Juan Islands archipelago and is the county seat of San Juan County. History In 1845 the Hudson's Bay Company laid claim to San Juan Island. In 1850 they built a salmon curing station. A few years later they started a sheep farm. The town's name originates from Joseph Poalie Friday, a native Hawaiian. Friday worked at the Pugets Sound Agricultural Company's Fort Cowlitz, from 1841 to 1859–60 and later moved north to San Juan Island, raising and herding sheep around the harbor. After the peaceful settlement obtained following the Pig War, the San Juan Islands became a separate county in 1873. Friday Harbor was named the county seat. Friday Harbor was officially incorporated on February 10, 1909. It remains the only incorporated town in the San Juan Islands. File:Salmon cann ...
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Puget Sound
Puget Sound ( ) is a sound of the Pacific Northwest, an inlet of the Pacific Ocean, and part of the Salish Sea. It is located along the northwestern coast of the U.S. state of Washington. It is a complex estuarine system of interconnected marine waterways and basins, with one major and two minor connections to the open Pacific Ocean via the Strait of Juan de Fuca—Admiralty Inlet being the major connection and Deception Pass and Swinomish Channel being the minor. Water flow through Deception Pass is approximately equal to 2% of the total tidal exchange between Puget Sound and the Strait of Juan de Fuca. Puget Sound extends approximately from Deception Pass in the north to Olympia in the south. Its average depth is and its maximum depth, off Jefferson Point between Indianola and Kingston, is . The depth of the main basin, between the southern tip of Whidbey Island and Tacoma, is approximately . In 2009, the term Salish Sea was established by the United States Board o ...
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Phi Beta Kappa
The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal arts and sciences, and to induct the most outstanding students of arts and sciences at only select American colleges and universities. It was founded at the College of William and Mary on December 5, 1776, as the first collegiate Greek-letter fraternity and was among the earliest collegiate fraternal societies. Since its inception, 17 U.S. Presidents, 40 U.S. Supreme Court Justices, and 136 Nobel Laureates have been inducted members. Phi Beta Kappa () stands for ('), which means "Wisdom it. love of knowledgeis the guide it. helmsmanof life". Membership Phi Beta Kappa has chapters in only about 10% of American higher learning institutions, and only about 10% of these schools' Arts and Sciences graduates are invited to join the soc ...
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