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GeneMatrix
GeneMatrix Inc is a Korean company servicing molecular diagnostics. The company is listed on KOSDAQ:109820. Its main service is to diagnose DNA mutations based on its proprietary technology of restriction fragment mass polymorphism (RFMP). GeneMatrix is affiliated with the Seoul National University Medical Center, the largest oncology center in Korea. History GeneMatrix Inc was founded in 2000 by former employees of CJ CheilJedang, CJ Cheil Jedang, one of South Korea's largest conglomerates. In 2001, VARIAGENICS, INC.(NASDAQ Biotechnology Index, Nasdaq: VGNX)who was a leader in pharmacogenomics, entered into a research and development collaboration with GeneMatrix Inc which had been applying genomic technology to the development of drugs and diagnostics to treat cancer. The ultimate goal was to develop molecular diagnostic products that would predict the body's response to leading drugs in the treatment of colon and gastric cancer. WangDon Yoo, CEO and President of GeneMatri ...
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Restriction Fragment Mass Polymorphism
Restriction Fragment Mass Polymorphism (RFMP) is a technology which Restriction digest, digests DNA into oligonucleotide fragments, and detects variation of DNA sequences by molecular weight of the fragments. RFMP is a Property, proprietary technology of GeneMatrix and can be utilized for genotyping viruses and microorganisms, and for human genome research. It is relatively restricted in usage due to the existence of many other genotyping products. Overview Restriction fragment mass polymorphism (RFMP) is an application of Maldi-TOF, matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF), used for identifying individual nucleotides from a DNA fragment, most commonly used in labeling Single-nucleotide polymorphism, single nucleotide polymorphisms (SNP). RFMP was developed as a successor to the similar restriction fragment length polymorphism (RFLP) with the intent to allow for more SNPs. Rather than read out lengths of fragments as RFLP does, the individual nucleotid ...
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