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Genain Quadruplets
The Genain quadruplets (born in 1930) are a set of identical quadruplet sisters. All four developed schizophrenia, suggesting a large genetic component to the cause of the disease. The pseudonym ''Genain'', used to protect the identity of the family, comes from the Greek, meaning ''dire ''(αἶνος)'' birth ''(γεν-). The sisters were given the pseudonyms Nora, Iris, Myra and Hester, to represent each of the four letters in NIMH, the acronym for the United States National Institute of Mental Health. Nora, Iris, and Hester were hospitalized for their schizophrenia at least once each. As of 2011, Iris and Hester had died. Personal lives The sisters were born in a midwestern American town (nicknamed "Envira") on April 14, 1930. They were considered local celebrities due to the quadruple nature of their birth. The four sisters grew up with their parents in the same household. The Genain sisters' parents were described as "disturbed". Their paternal grandmother may have had para ...
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Quadruplet
A multiple birth is the culmination of one multiple pregnancy, wherein the mother gives birth to two or more babies. A term most applicable to vertebrate species, multiple births occur in most kinds of mammals, with varying frequencies. Such births are often named according to the number of offspring, as in ''twins'' and ''triplets''. In non-humans, the whole group may also be referred to as a ''litter'', and multiple births may be more common than single births. Multiple births in humans are the exception and can be exceptionally rare in the largest mammals. A multiple pregnancy may be the result of the fertilization of a single egg that then splits to create identical fetuses, or it may be the result of the fertilization of multiple eggs that create fraternal ("non-identical") fetuses, or it may be a combination of these factors. A multiple pregnancy from a single zygote is called ''monozygotic'', from two zygotes is called ''dizygotic'', or from three or more zygotes is cal ...
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Schizophrenia
Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdrawal, decreased emotional expression, and apathy. Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a history that includes the person's reported experiences, and reports of others familiar with the person. To be diagnosed with schizophrenia, symptoms and functional impairment need to be present for six months ( DSM-5) or one month (ICD-11). Many people with schizophrenia have other mental disorders, especially substance use disorders, depressive disorders, anxiety disorders, and obsessive–compulsive disorder. About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetim ...
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ...
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Stamford, Connecticut
Stamford () is a city in the U.S. state of Connecticut, outside of Manhattan. It is Connecticut's second-most populous city, behind Bridgeport. With a population of 135,470, Stamford passed Hartford and New Haven in population as of the 2020 census. It is in the Bridgeport-Stamford-Norwalk-Danbury metropolitan statistical area, which is part of the New York City metropolitan area (specifically, the New York–Newark, NY–NJ–CT–PA Combined Statistical Area). As of 2019, Stamford is home to nine Fortune 500 companies and numerous divisions of large corporations. This gives it the largest financial district in the New York metropolitan region outside New York City and one of the nation's largest concentrations of corporations. Dominant sectors of Stamford's economy include financial services, tourism, information technology, healthcare, telecommunications, transportation, and retail. Its metropolitan division is home to colleges and universities including UConn Stamf ...
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Greek Language
Greek ( el, label= Modern Greek, Ελληνικά, Elliniká, ; grc, Ἑλληνική, Hellēnikḗ) is an independent branch of the Indo-European family of languages, native to Greece, Cyprus, southern Italy ( Calabria and Salento), southern Albania, and other regions of the Balkans, the Black Sea coast, Asia Minor, and the Eastern Mediterranean. It has the longest documented history of any Indo-European language, spanning at least 3,400 years of written records. Its writing system is the Greek alphabet, which has been used for approximately 2,800 years; previously, Greek was recorded in writing systems such as Linear B and the Cypriot syllabary. The alphabet arose from the Phoenician script and was in turn the basis of the Latin, Cyrillic, Armenian, Coptic, Gothic, and many other writing systems. The Greek language holds a very important place in the history of the Western world. Beginning with the epics of Homer, ancient Greek literature includes many works ...
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United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo-Americ ...
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National Institute Of Mental Health
The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. NIMH is the largest research organization in the world specializing in mental illness. Joshua A. Gordon is the current director of NIMH. The institute was first authorized by the U.S. government in 1946, when then President Harry Truman signed into law the National Mental Health Act, although the institute was not formally established until 1949. NIMH is a $1.5 billion enterprise, supporting research on mental health through grants to investigators at institutions and organizations throughout the United States and through its own internal (intramural) research effort. The mission of NIMH is "to transform the understanding and treatment of me ...
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Schizophrenia Research
''Schizophrenia Research'' is a peer-reviewed medical journal covering research on the cause, clinical diagnostics, and treatment of schizophrenia. It is an official journal of the Schizophrenia International Research Society and was established in 1988. The editor-in-chief is Matcheri Keshavan and the former editors are Henry Nasrallah (University of Cincinnati) and Lynn DeLisi (Harvard Medical School). According to ''Schizophrenia Researchs original mission statement, the journal is aimed at According to the ''Journal Citation Reports'', the journal has a 2018 impact factor of 4.56 See also * List of psychiatry journals * ''Schizophrenia Bulletin ''Schizophrenia Bulletin'' is a peer-reviewed medical journal which covers research relating to the etiology and treatment of schizophrenia. The journal is published bimonthly by Oxford University Press in association with the Maryland Psychiatric ...'' References External links * {{Official website, https://www.journ ...
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Schizophrenia Bulletin
''Schizophrenia Bulletin'' is a peer-reviewed medical journal which covers research relating to the etiology and treatment of schizophrenia. The journal is published bimonthly by Oxford University Press in association with the Maryland Psychiatric Research Center and Schizophrenia International Research Society. According to the ''Journal Citation Reports'', the journal's 2020 impact factor is 9.306. The front cover of the journal traditionally depicts a work of art by a person with a mental disorder. The founder and first editor-in-chief of ''Schizophrenia Bulletin'' was American psychiatrist Loren Mosher. See also * ''Schizophrenia Research'' * List of psychiatry journals The following is a list of journals in the field of psychiatry. Psychiatry journals generally publish articles with either a general focus (meaning all aspects of psychiatry are included) or with a more specific focus. This list includes notable p ... References External links * English-language ...
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Female Genital Mutilation
Female genital mutilation (FGM), also known as female genital cutting, female genital mutilation/cutting (FGM/C) and female circumcision, is the ritual cutting or removal of some or all of the external female genitalia. The practice is found in some countries of Africa, Asia and the Middle East, and within communities abroad from countries in which FGM is common. UNICEF estimated, in 2016, that 200 million women in 30 countries—Indonesia, Iraq, Yemen, and 27 African countries including Egypt—had been subjected to one or more types of FGM. Typically carried out by a traditional circumciser using a blade, FGM is conducted from days after birth to puberty and beyond. In half of the countries for which national statistics are available, most girls are cut before the age of five. Procedures differ according to the country or ethnic group. They include removal of the clitoral hood (type 1-a) and clitoral glans (1-b); removal of the inner labia; and removal of the inner and ...
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Psychiatry Research
''Psychiatry Research'' is a peer-reviewed medical journal covering psychiatry. It was established in 1979 and is published 21 times per year by Elsevier. A section of the journal, '' Psychiatry Research: Neuroimaging'', covers the discipline of neuroimaging as it pertains to psychiatry. The editor-in-chief is Lynn DeLisi. According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 11.225. References External links * Psychiatry journals Elsevier academic journals Publications established in 1979 English-language journals {{psychiatry-journal-stub ...
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1930 Births
Year 193 ( CXCIII) was a common year starting on Monday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Sosius and Ericius (or, less frequently, year 946 '' Ab urbe condita''). The denomination 193 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * January 1 – Year of the Five Emperors: The Roman Senate chooses Publius Helvius Pertinax, against his will, to succeed the late Commodus as Emperor. Pertinax is forced to reorganize the handling of finances, which were wrecked under Commodus, to reestablish discipline in the Roman army, and to suspend the food programs established by Trajan, provoking the ire of the Praetorian Guard. * March 28 – Pertinax is assassinated by members of the Praetorian Guard, who storm the imperial palace. The Empire is auc ...
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