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Goulard's Extract
Basic lead acetate, also known as subacetate of lead, is the inorganic compound with the formula Pb3(OH)4(O2CCH3)2. A white solid, it is one of several lead acetates. History Goulard's extract is a solution of lead(II) acetate and lead(II) oxide used as an astringent during the 18th, 19th and early 20th centuries. It was named after its introducer, Thomas Goulard. Lead poisoning and the development of more effective astringents caused doctors to abandon its use. Synonymous or very closely related formulations were known as ''liquor plumbi subacetis dilutus'', ''eau de Goulard'', extract of Saturn Saturn is the sixth planet from the Sun and the second-largest in the Solar System, after Jupiter. It is a gas giant with an average radius of about nine and a half times that of Earth. It has only one-eighth the average density of Earth; h ..., vinegar of Saturn, and liquid acetate of lead. The white water ''eau de Saturne'' differed from ''eau de Goulard'' in not containing ...
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Lead Acetate
Lead acetate can refer to: * Lead subacetate (Basic lead acetate), Pb3(OH)4(CH3COO)2 * Lead(IV) acetate (plumbic acetate), Pb(CH3COO)4 * Lead(II) acetate Lead(II) acetate (Pb(CH3COO)2), also known as lead acetate, lead diacetate, plumbous acetate, sugar of lead, lead sugar, salt of Saturn, or Goulard's powder, is a white crystalline chemical compound with a slightly sweet taste. Like many other l ... (lead diacetate), Pb(CH3COO)2 and the trihydrate Pb(CH3COO)2.3H2O {{Chemistry index ...
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Lead(II) Acetate
Lead(II) acetate (Pb(CH3COO)2), also known as lead acetate, lead diacetate, plumbous acetate, sugar of lead, lead sugar, salt of Saturn, or Goulard's powder, is a white crystalline chemical compound with a slightly sweet taste. Like many other lead compounds, it is toxic. Lead acetate is soluble in water and glycerin. With water it forms the trihydrate, Pb(CH3COO)2·3H2O, a colourless or white efflorescent monoclinic crystalline substance. The substance is used as a reagent to make other lead compounds and as a fixative for some dyes. In low concentrations, it is the principal active ingredient in progressive types of hair colouring dyes. Lead(II) acetate is also used as a mordant in textile printing and dyeing, and as a drier in paints and varnishes. It was historically used as a sweetener and preservative in wines and in other foods and for cosmetics. Production Lead acetate can be made by boiling elemental lead in acetic acid and hydrogen peroxide. This method will also work ...
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Lead(II) Oxide
Lead(II) oxide, also called lead monoxide, is the inorganic compound with the molecular formula Pb O. PbO occurs in two polymorphs: litharge having a tetragonal crystal structure, and massicot having an orthorhombic crystal structure. Modern applications for PbO are mostly in lead-based industrial glass and industrial ceramics, including computer components. It is an amphoteric oxide. Types Lead oxide exists in two types: * Red tetragonal (α-PbO), obtained at lower temperatures than the β-PbO * Yellow orthorhombic (β-PbO), which is obtained temperatures higher than Synthesis PbO may be prepared by heating lead metal in air at approximately . At this temperature it is also the end product of decomposition of other oxides of lead in air: :PbO2->[] Pb12O19 ->[] Pb12O17 ->[] Pb3O4 ->[] PbO Thermal decomposition of lead(II) nitrate or lead carbonate, lead(II) carbonate also results in the formation of PbO: :2  → 2 PbO + 4  + : → PbO + PbO is produced ...
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Astringent
An astringent (sometimes called adstringent) is a chemical that shrinks or constricts body tissues. The word derives from the Latin ''adstringere'', which means "to bind fast". Calamine lotion, witch hazel, and yerba mansa, a Californian plant, are astringents. Astringency, the dry, puckering or numbing mouthfeel caused by the tannins in unripe fruits, lets the fruit mature by deterring eating. Ripe fruits and fruit parts including blackthorn (sloe berries), ''Aronia'' chokeberry, chokecherry, bird cherry, rhubarb, quince and persimmon fruits (especially those which are unripe), banana skins (or unripe bananas), cashew fruits and acorns are astringent. Citrus fruits, like lemons, are somewhat astringent. Tannins, being a kind of polyphenol, bind salivary proteins and make them precipitate and aggregate, producing a rough, "sandpapery", or dry sensation in the mouth. The tannins in some teas, coffee, and red grape wines like Cabernet Sauvignon and Merlot produce mild as ...
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Thomas Goulard
Thomas Goulard (1697–1784) was a French surgeon famous for Goulard's extract, a solution of lead(II) acetate and lead(II) oxide which was formerly used as an astringent. Goulard was a surgeon and anatomist in Montpellier who specialized in genitourinary The genitourinary system, or urogenital system, are the organs of the reproductive system and the urinary system. These are grouped together because of their proximity to each other, their common embryological origin and the use of common pathwa ... disorders. His best known written work is titled ''Oeuvres de Chirurgie''. References 1697 births 1784 deaths French surgeons {{France-med-bio-stub 18th-century surgeons ...
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Lead Poisoning
Lead poisoning, also known as plumbism and saturnism, is a type of metal poisoning caused by lead in the body. The brain is the most sensitive. Symptoms may include abdominal pain, constipation, headaches, irritability, memory problems, infertility, and tingling in the hands and feet. It causes almost 10% of intellectual disability of otherwise unknown cause and can result in behavioral problems. Some of the effects are permanent. In severe cases, anemia, seizures, coma, or death may occur. Exposure to lead can occur by contaminated air, water, dust, food, or consumer products. Lead poisoning poses a significantly increased risk to children as they are far more likely to ingest lead indirectly by chewing on toys or other objects that are coated in lead paint. The amount of lead that can be absorbed by children is also higher than that of adults. Exposure at work is a common cause of lead poisoning in adults with certain occupations at particular risk. Diagnosis is typically by ...
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Alchemical Symbol
Alchemical symbols, originally devised as part of alchemy, were used to denote some elements and some compounds until the 18th century. Although notation like this was mostly standardized, style and symbol varied between alchemists, so this page mainly lists the most common ones. Three primes According to Paracelsus (1493–1541), the three primes or ''tria prima'' – of which material substances are immediately composed – are: * Sulfur or soul, the principle of combustibility: 🜍 () * Mercury or spirit, the principle of fusibility and volatility: ☿ () * Salt or body, the principle of non-combustibility and non-volatility: 🜔 () Four basic elements Western alchemy makes use of the four classical elements. The symbols used for these are: * Air 🜁 () * Earth 🜃 () * Fire 🜂 () * Water 🜄 () Seven The seven metals known since Classical times in Europe were associated with the seven classical planets; this figured heavily in alchemical symbolism. The exact ...
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History Of Pharmacy
The history of pharmacy as an independent science dates back to the first third of the 19th century. Before then, pharmacy evolved from antiquity as part of medicine. The history of pharmacy coincides well with the history of medicine, but it's important that there is a distinction between the two topics. Pharmaceuticals is one of the most-researched fields in the academic industry, but the history surrounding that particular topic is sparse compared to the impact its made world-wide. Before the advent of pharmacists, there existed apothecaries that worked alongside priests and physicians in regard to patient care. Prehistoric Pharmacy Paleopharmacological studies attest to the use of medicinal plants in pre-history. For example, herbs were discovered in the Shanidar Cave, and remains of the areca nut (''Areca catechu)'' in the Spirit Cave. Prehistoric man learned pharmaceutical techniques through instinct, by watching birds and beasts, and using cool water, leaves, dirt, or ...
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