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Gaetano T. Montelione
Gaetano T. Montelione is an American biophysical chemist, Professor of Chemistry and Chemical Biology, and Constellation Endowed Chair in Structural Bioinformatics at Rensselaer Polytechnic Institute in Troy, NY. His research program includes work on Nuclear Magnetic Resonance (NMR) pulse sequence development, software for automated analysis of protein NMR data, and applications of structural bioinformatics in biomedical research. Background and education Gaetano Montelione was born in the Bronx, NY. He graduated from Half Hollow Hills High School in Dix Hills, NY. He received a B.S. with Highest Honors in Biochemistry from Cornell University in Ithaca, NY, and completed a Ph.D. in Physical Chemistry at Cornell University under the joint mentorship of Harold A. Scheraga (Cornell) and Kurt Wüthrich ( ETH - Zürich). Montelione carried out post-doctoral research in protein NMR pulse sequence development in the laboratory of Gerhard Wagner in the Biophysics Research Division a ...
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Molecular Biophysics
Molecular biophysics is a rapidly evolving interdisciplinary area of research that combines concepts in physics, chemistry, engineering, mathematics and biology. It seeks to understand biomolecular systems and explain biological function in terms of molecular structure, structural organization, and dynamic behaviour at various levels of complexity (from single molecules to supramolecular structures, viruses and small living systems). This discipline covers topics such as the measurement of molecular forces, molecular associations, allosteric interactions, Brownian motion, and cable theory. Additional areas of study can be found on Outline of Biophysics. The discipline has required development of specialized equipment and procedures capable of imaging and manipulating minute living structures, as well as novel experimental approaches. Overview Molecular biophysics typically addresses biological questions similar to those in biochemistry and molecular biology, seeking to find the ...
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National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ...
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Rutgers University Faculty
This is an enumeration of notable people affiliated with Rutgers University, including graduates of the undergraduate and graduate and professional programs at all three campuses, former students who did not graduate or receive their degree, presidents of the university, current and former professors, as well as members of the board of trustees and board of governors, and coaches affiliated with the university's athletic program. Also included are characters in works of fiction (books, films, television shows, et cetera) who have been mentioned or were depicted as having an affiliation with Rutgers, either as a student, alumnus, or member of the faculty. Some noted alumni and faculty may be also listed in the main Rutgers University article or in some of the affiliated articles. Individuals are sorted by category and alphabetized within each category. Default campus for listings is the New Brunswick campus, the systems' largest campus, with Camden and Newark campus affiliat ...
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Scientists From The Bronx
A scientist is a person who conducts scientific research to advance knowledge in an area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engaged in the philosophical study of nature called natural philosophy, a precursor of natural science. Though Thales (circa 624-545 BC) was arguably the first scientist for describing how cosmic events may be seen as natural, not necessarily caused by gods,Frank N. Magill''The Ancient World: Dictionary of World Biography'', Volume 1 Routledge, 2003 it was not until the 19th century that the term ''scientist'' came into regular use after it was coined by the theologian, philosopher, and historian of science William Whewell in 1833. In modern times, many scientists have advanced degrees in an area of science and pursue careers in various sectors of the economy such as academia, industry, government, and nonprofit environments.'''' History The roles ...
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Rensselaer Polytechnic Institute Faculty
Rensselaer may refer to: Places *Rensselaer, Indiana, a city ** Rensselaer (Amtrak station), serving the city *Rensselaer, Missouri, a village *Rensselaer County, New York *Rensselaer, New York, a city in Rensselaer County * Rensselaer Falls, New York, a village in St. Lawrence County * Rensselaerville, New York, a town in Albany County *Manor of Rensselaerswyck, the Van Rensselaer family's estate during colonial times People * Van Rensselaer (surname) * Rensselaer Morse Lewis (1820-1888), Wisconsin state legislator * Rensselaer Nelson (1826-1904), U.S. federal judge * Rensselaer Westerlo (1776–1851), U.S. Congressman from New York * Bret Rensselaer, an American-born, British spy in the Bernard Samson novels Other * Rensselaer Polytechnic Institute, a university in Troy, New York See also * Van Rensselaer (other) Van Rensselaer may refer to: *Van Rensselaer family, a prominent Dutch American family *Van Rensselaer (surname), a surname (including a list of people w ...
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CASP
Critical Assessment of Structure Prediction (CASP), sometimes called Critical Assessment of Protein Structure Prediction, is a community-wide, worldwide experiment for protein structure prediction taking place every two years since 1994. CASP provides research groups with an opportunity to objectively test their structure prediction methods and delivers an independent assessment of the state of the art in protein structure modeling to the research community and software users. Even though the primary goal of CASP is to help advance the methods of identifying protein three-dimensional structure from its amino acid sequence many view the experiment more as a “world championship” in this field of science. More than 100 research groups from all over the world participate in CASP on a regular basis and it is not uncommon for entire groups to suspend their other research for months while they focus on getting their servers ready for the experiment and on performing the detailed predic ...
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Protein Data Bank
The Protein Data Bank (PDB) is a database for the three-dimensional structural data of large biological molecules, such as proteins and nucleic acids. The data, typically obtained by X-ray crystallography, NMR spectroscopy, or, increasingly, cryo-electron microscopy, and submitted by biologists and biochemists from around the world, are freely accessible on the Internet via the websites of its member organisations (PDBe, PDBj, RCSB, and BMRB). The PDB is overseen by an organization called the Worldwide Protein Data Bank, wwPDB. The PDB is a key in areas of structural biology, such as structural genomics. Most major scientific journals and some funding agencies now require scientists to submit their structure data to the PDB. Many other databases use protein structures deposited in the PDB. For example, SCOP and CATH classify protein structures, while PDBsum provides a graphic overview of PDB entries using information from other sources, such as Gene ontology. History Two force ...
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Homology Modeling
Homology modeling, also known as comparative modeling of protein, refers to constructing an atomic-resolution model of the "''target''" protein from its amino acid sequence and an experimental three-dimensional structure of a related homologous protein (the "''template''"). Homology modeling relies on the identification of one or more known protein structures likely to resemble the structure of the query sequence, and on the production of an alignment that maps residues in the query sequence to residues in the template sequence. It has been seen that protein structures are more conserved than protein sequences amongst homologues, but sequences falling below a 20% sequence identity can have very different structure. Evolutionarily related proteins have similar sequences and naturally occurring homologous proteins have similar protein structure. It has been shown that three-dimensional protein structure is evolutionarily more conserved than would be expected on the basis of sequence ...
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Protein Structure Initiative
The Protein Structure Initiative (PSI) was a USA based project that aimed at accelerating discovery in structural genomics and contribute to understanding biological function. Funded by the U.S. National Institute of General Medical Sciences (NIGMS) between 2000 and 2015, its aim was to reduce the cost and time required to determine three-dimensional protein structures and to develop techniques for solving challenging problems in structural biology, including membrane proteins. Over a dozen research centers have been supported by the PSI for work in building and maintaining high-throughput structural genomics pipelines, developing computational protein structure prediction methods, organizing and disseminating information generated by the PSI, and applying high-throughput structure determination to study a broad range of important biological and biomedical problems. The project has been organized into three separate phases. The first phase of the Protein Structure Initiative (PSI- ...
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Aaron Shatkin
Aaron J. Shatkin (18 July 1934 – 4 June 2012) was an American professor and director of the Center for Advanced Biotechnology and Medicine at Rutgers University and a scientist at the Cancer Institute of New Jersey at Robert Wood Johnson Medical School. He was known for his work as a virologist studying reoviruses. Education Shatkin graduated from ''summa cum laude'' Bowdoin College in chemistry in 1956. He earned a PhD from The Rockefeller University in 1961, working in the laboratory of Edward Tatum studying ''Neurospora crassa''. Career Shatkin began studying reoviruses as a postdoctoral fellow at the National Institutes of Health with Norman Salzman. He then opened his own laboratory at the Roche Institute of Molecular Biology in Nutley, New Jersey, studying mRNA in reoviruses. In 1985, he moved to Rutgers University, where he was a University Professor of Molecular Biology. He was the founding director of the Center for Advanced Biotechnology and Medicine at Rutgers a ...
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