Funding Bias
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Funding Bias
Funding bias, also known as sponsorship bias, funding outcome bias, funding publication bias, and funding effect, refers to the tendency of a scientific study to support the interests of the study's financial sponsor. This phenomenon is recognized sufficiently that researchers undertake studies to examine bias in past published studies. Funding bias has been associated, in particular, with research into chemical toxicity, tobacco, and pharmaceutical drugs. It is an instance of experimenter's bias. Causes Human nature The psychology text '' Influence: Science and Practice'' describes the act of reciprocity as a trait in which a person feels obliged to return favors. This trait is embodied in all human cultures. Human nature may influence even the most ethical researchers to be affected by their sponsors, although they may genuinely deny it. Misconduct Scientific malpractice involving shoddy research or data manipulation does occur in rare instances. Often, however, the quality o ...
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Experimenter's Bias
Observer bias is one of the types of detection bias and is defined as any kind of systematic divergence from accurate facts during observation and the recording of data and information in studies. The definition can be further expanded upon to include the systematic difference between what is observed due to variation in observers, and what the true value is. Observer bias is the tendency of observers to not see what is there, but instead to see what they expect or want to see. This is a common occurrence in the everyday lives of many and is a significant problem that is sometimes encountered in scientific research and studies. Observation is critical to scientific research and activity, and as such, observer bias may be as well. When such biases exist, scientific studies can result in an over- or underestimation of what is true and accurate, which compromises the validity of the findings and results of the study, even if all other designs and procedures in the study were appropriate ...
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Bisphenol A
Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. It is a colourless solid which is soluble in most common organic solvents, but has very poor solubility in water. BPA is produced on an industrial scale by the condensation of phenol and acetone, and has a global production scale which is expected to reach 10 million tonnes in 2022. BPA's largest single application is as a co-monomer in the production of polycarbonates, which accounts for 65–70% of all BPA production. The manufacturing of epoxy resins and vinyl ester resins account for 25–30% of BPA use. The remaining 5% is used as a major component of several high-performance plastics, and as a minor additive in PVC, polyurethane, thermal paper, and several other materials. It is not a plasticizer, although it is often wrongly labelled as such. The health effects of BPA have been the subject of prolonged public and scientific debate. BPA is a xenoestrogen, exhibiting hormone ...
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Academic Publishing
Academic publishing is the subfield of publishing which distributes academic research and scholarship. Most academic work is published in academic journal articles, books or theses. The part of academic written output that is not formally published but merely printed up or posted on the Internet is often called "grey literature". Most scientific and scholarly journals, and many academic and scholarly books, though not all, are based on some form of peer review or editorial refereeing to qualify texts for publication. Peer review quality and selectivity standards vary greatly from journal to journal, publisher to publisher, and field to field. Most established academic disciplines have their own journals and other outlets for publication, although many academic journals are somewhat interdisciplinary, and publish work from several distinct fields or subfields. There is also a tendency for existing journals to divide into specialized sections as the field itself becomes more spec ...
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Regulatory Capture
In politics, regulatory capture (also agency capture and client politics) is a form of corruption of authority that occurs when a political entity, policymaker, or regulator is co-opted to serve the commercial, ideological, or political interests of a minor constituency, such as a particular geographic area, industry, profession, or ideological group. When regulatory capture occurs, a special interest is prioritized over the general interests of the public, leading to a net loss for society. The theory of client politics is related to that of rent-seeking and political failure; client politics "occurs when most or all of the benefits of a program go to some single, reasonably small interest (e.g., industry, profession, or locality) but most or all of the costs will be borne by a large number of people (for example, all taxpayers)". Theory For public choice theorists, regulatory capture occurs because groups or individuals with high-stakes interests in the outcome of policy or re ...
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Metascience (research)
Metascience (also known as meta-research) is the use of scientific methodology to study science itself. Metascience seeks to increase the quality of scientific research while reducing inefficiency. It is also known as "''research on research''" and "''the science of science''", as it uses research methods to study how research is done and find where improvements can be made. Metascience concerns itself with all fields of research and has been described as "a bird's eye view of science". In the words of John Ioannidis, "Science is the best thing that has happened to human beings ... but we can do it better." In 1966, an early meta-research paper examined the statistical methods of 295 papers published in ten high-profile medical journals. It found that "in almost 73% of the reports read ... conclusions were drawn when the justification for these conclusions was invalid." Meta-research in the following decades found many methodological flaws, inefficiencies, and poor practices in r ...
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Conflicts Of Interest In Academic Publishing
Conflicts of interest (COIs) often arise in academic publishing. Such conflicts may cause wrongdoing and make it more likely. Ethical standards in academic publishing exist to avoid and deal with conflicts of interest, and the field continues to develop new standards. Standards vary between journals and are unevenly applied. According to the International Committee of Medical Journal Editors, " thors have a responsibility to evaluate the integrity, history, practices and reputation of the journals to which they submit manuscripts". Conflicts of interest increase the likelihood of biases arising; they can harm the quality of research and the public good (even if disclosed). Conflicts of interest can involve research sponsors, authors, journals, journal staff, publishers, and peer reviewers. Avoidance, disclosure, and tracking The avoidance of conflicts of interest and the changing of the structure of institutions to make them easier to avoid are frequently advocated for. Some in ...
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Conflict Of Interest
A conflict of interest (COI) is a situation in which a person or organization is involved in multiple interests, financial or otherwise, and serving one interest could involve working against another. Typically, this relates to situations in which the personal interest of an individual or organization might adversely affect a duty owed to make decisions for the benefit of a third party. An "interest" is a commitment, obligation, duty or goal associated with a particular social role or practice. By definition, a "conflict of interest" occurs if, within a particular decision-making context, an individual is subject to two coexisting interests that are in direct conflict with each other. Such a matter is of importance because under such circumstances the decision-making process can be disrupted or compromised in a manner that affects the integrity or the reliability of the outcomes. Typically, a conflict of interest arises when an individual finds themselves occupying two soc ...
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Advocacy Group
Advocacy groups, also known as interest groups, special interest groups, lobbying groups or pressure groups use various forms of advocacy in order to influence public opinion and ultimately policy. They play an important role in the development of political and social systems. Motives for action may be based on Politics, political, religious, morality, moral, or commerce, commercial positions. Groups Methods used by advocacy groups, use varied methods to try to achieve their aims, including lobbying, media campaigns, consciousness raising, awareness raising publicity stunts, Opinion poll, polls, research, and policy briefings. Some groups are supported or backed by powerful business or political interests and exert considerable influence on the political process, while others have few or no such resources. Some have developed into important social, political institutions or social movements. Some powerful advocacy groups have been accused of manipulating the democratic syste ...
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Cochrane Review
Cochrane (previously known as the Cochrane Collaboration) is a British international charitable organisation formed to organise medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers. It includes 53 review groups that are based at research institutions worldwide. Cochrane has approximately 30,000 volunteer experts from around the world. The group conducts systematic reviews of health-care interventions and diagnostic tests and publishes them in the Cochrane Library. According to the Library, articles are available via one-click access, but some require paid subscription or registration before reading. A few reviews, in occupational health for example, incorporate results from non-randomised observational studies as well as controlled before–after (CBA) studies and interrupted time-series studies. History Cochrane, previously known as the Cochrane Collaboration, was founded in 1 ...
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Sugar Marketing
Sugar is heavily marketed both by sugar producers and the producers of sugary drinks and foods. Apart from direct marketing methods such as messaging on packaging, television ads, advergames, and product placement in setting like blogs, industry has worked to steer coverage of sugar-related health information in popular media, including news media and social media. Sugar refiners and manufacturers of sugary foods and drinks have also sought to influence medical research and public health recommendations. The results of research on the health effects of sugary food and drink differ significantly, depending on whether the researcher has financial ties to the food and drink industry. The authors of a 2016 review of funding bias concluded that "This industry seems to be manipulating contemporary scientific processes to create controversy and advance their business interests at the expense of the public's health". History In the early 1950s, sugar was marketed as a healthy subst ...
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Johnson & Johnson
Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company is ranked No. 36 on the 2021 Fortune 500 list of the largest United States corporations by total revenue. Johnson & Johnson is one of the List of public corporations by market capitalization, world's most valuable companies, and is one of only two U.S.-based companies that has a prime credit rating of AAA, higher than that of the United States government. Johnson & Johnson is headquartered in New Brunswick, New Jersey, the consumer division being located in Skillman, New Jersey. The corporation includes some 250 subsidiary companies with operations in 60 countries and products sold in over 175 countries. Johnson & Johnson had worldwide sales of $93.8billion during calendar year 2021. Johnson & Johnson's brands include numerous household na ...
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Splenda
Splenda is a global brand of sugar substitutes and reduced-calorie food products. While the company is known for its original formulation containing sucralose, it also manufactures items using natural sweeteners such as stevia, monk fruit and allulose. It is owned by the American company Heartland Food Products Group. The high-intensity sweetener ingredient sucralose used in Splenda Original is manufactured by the British company Tate & Lyle. Sucralose was discovered by Tate & Lyle and researchers at Queen Elizabeth College, University of London, in 1976. Tate & Lyle subsequently developed sucralose-based Splenda products in partnership with Johnson & Johnson subsidiary McNeil Nutritionals, LLC. The Splenda brand was transferred to Heartland Food Products Group after their purchase of the line with investor Centerbridge Partners in 2015. Since its approval by the United States government in 1998 and introduction there in 1999, sucralose has overtaken Equal in the $1.5-billi ...
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