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FreeSurfer
FreeSurfer is a brain imaging software package originally developed by Bruce Fischl, Anders Dale, Martin Sereno, and Doug Greve. Development and maintenance of FreeSurfer is now the primary responsibility of the Laboratory for Computational Neuroimaging at the Athinoula A. Martinos Center for Biomedical Imaging. FreeSurfer contains a set of programs with a common focus of analyzing magnetic resonance imaging (MRI) scans of brain tissue. It is an important tool in functional brain mapping and contains tools to conduct both volume based and surface based analysis. FreeSurfer includes tools for the reconstruction of topologically correct and geometrically accurate models of both the gray/white and pial surfaces, for measuring cortical thickness, surface area and folding, and for computing inter-subject registration based on the pattern of cortical folds. 57,541 copies of the FreeSurfer software package have been registered for use as of April 2022 and it is a core tool in the pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spherical Registration
A sphere () is a geometrical object that is a three-dimensional analogue to a two-dimensional circle. A sphere is the set of points that are all at the same distance from a given point in three-dimensional space.. That given point is the centre of the sphere, and is the sphere's radius. The earliest known mentions of spheres appear in the work of the ancient Greek mathematicians. The sphere is a fundamental object in many fields of mathematics. Spheres and nearly-spherical shapes also appear in nature and industry. Bubbles such as soap bubbles take a spherical shape in equilibrium. The Earth is often approximated as a sphere in geography, and the celestial sphere is an important concept in astronomy. Manufactured items including pressure vessels and most curved mirrors and lenses are based on spheres. Spheres roll smoothly in any direction, so most balls used in sports and toys are spherical, as are ball bearings. Basic terminology As mentioned earlier is the sphere's r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroimaging
Neuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Increasingly it is also being used for quantitative studies of brain disease and psychiatric illness. Neuroimaging is a highly multidisciplinary research field and is not a medical specialty. Neuroimaging differs from neuroradiology which is a medical specialty and uses brain imaging in a clinical setting. Neuroradiology is practiced by radiologists who are medical practitioners. Neuroradiology primarily focuses on identifying brain lesions, such as vascular disease, strokes, tumors and inflammatory disease. In contrast to neuroimaging, neuroradiology is qualitative (based on subjective impressions and extensive clinical training) but sometimes uses basic quantitative methods. Functional brain imaging techniques, such as functional magnet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computing In Medical Imaging
Computing is any goal-oriented activity requiring, benefiting from, or creating computing machinery. It includes the study and experimentation of algorithmic processes, and development of both hardware and software. Computing has scientific, engineering, mathematical, technological and social aspects. Major computing disciplines include computer engineering, computer science, cybersecurity, data science, information systems, information technology and software engineering. The term "computing" is also synonymous with counting and calculating. In earlier times, it was used in reference to the action performed by mechanical computing machines, and before that, to human computers. History The history of computing is longer than the history of computing hardware and includes the history of methods intended for pen and paper (or for chalk and slate) with or without the aid of tables. Computing is intimately tied to the representation of numbers, though mathematical conc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statistical Parametric Mapping
Statistical parametric mapping (SPM) is a statistical technique for examining differences in brain activity recorded during functional neuroimaging experiments. It was created by Karl Friston. It may alternatively refer to software created by the Wellcome Department of Imaging Neuroscience at University College London to carry out such analyses. Approach Unit of measurement Functional neuroimaging is one type of 'brain scanning'. It involves the measurement of brain activity. The measurement technique depends on the imaging technology (e.g., fMRI and PET). The scanner produces a 'map' of the area that is represented as voxels. Each voxel represents the activity of a specific volume in three-dimensional space. The exact size of a voxel varies depending on the technology. fMRI voxels typically represent a volume of 27 mm3 in an equilateral cuboid. Experimental design Researchers examine brain activity linked to a specific mental process or processes. One approach involves aski ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laboratory Of Neuro Imaging
A laboratory (; ; colloquially lab) is a facility that provides controlled conditions in which scientific or technological research, experiments, and measurement may be performed. Laboratory services are provided in a variety of settings: physicians' offices, clinics, hospitals, and regional and national referral centers. Overview The organisation and contents of laboratories are determined by the differing requirements of the specialists working within. A physics laboratory might contain a particle accelerator or vacuum chamber, while a metallurgy laboratory could have apparatus for casting or refining metals or for testing their strength. A chemist or biologist might use a wet laboratory, while a psychologist's laboratory might be a room with one-way mirrors and hidden cameras in which to observe behavior. In some laboratories, such as those commonly used by computer scientists, computers (sometimes supercomputers) are used for either simulations or the analysis of data. Scienti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Analysis Of Functional NeuroImages
Analysis of Functional NeuroImages (AFNI) is an open-source environment for processing and displaying functional MRI data—a technique for mapping human brain activity. AFNI is an agglomeration of programs that can be used interactively or flexibly assembled for batch processing using shell script. The term ''AFNI'' refers both to the entire suite and to a particular interactive program often used for visualization. AFNI is actively developed by the NIMH Scientific and Statistical Computing Core and its capabilities are continually expanding. AFNI runs under many Unix-like operating systems that provide X11 and Motif libraries, including IRIX, Solaris, Linux, FreeBSD and OS X. Precompiled binaries are available for some platforms. AFNI is available for research use under the GNU General Public License, the included SVM-light component is non-commercial and non-distributable. AFNI now comprises over 300,000 lines of C source code, and a skilled C programmer can add inter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AFNI
Analysis of Functional NeuroImages (AFNI) is an open-source environment for processing and displaying functional MRI data—a technique for mapping human brain activity. AFNI is an agglomeration of programs that can be used interactively or flexibly assembled for batch processing using shell script. The term ''AFNI'' refers both to the entire suite and to a particular interactive program often used for visualization. AFNI is actively developed by the NIMH Scientific and Statistical Computing Core and its capabilities are continually expanding. AFNI runs under many Unix-like operating systems that provide X11 and Motif libraries, including IRIX, Solaris, Linux, FreeBSD and OS X. Precompiled binaries are available for some platforms. AFNI is available for research use under the GNU General Public License, the included SVM-light component is non-commercial and non-distributable. AFNI now comprises over 300,000 lines of C source code, and a skilled C programmer can add inter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CARET (Computerized Anatomical Reconstruction And Editing Toolkit)
CARET (Computerized Anatomical Reconstruction Toolkit) is a software application for the structural and functional analysis of the cerebral and cerebellar cortex. CARET is developed in the Van Essen Laboratory in the Department of Anatomy and Neurobiology at the Washington University School of Medicine in St. Louis, Missouri. CARET is a free, open-source application distributed in both binary and source formats under the GNU General Public License. CARET runs on FreeBSD, Linux, Mac OS X, and Microsoft Windows. Image:Caret_software_image_of.jpg, Image of CARET main window with functional and foci data on surface CARET's capabilities * Analysis of group anatomical differences using sulcal depth morphometry. * Display of activation foci. * Generation of flat, inflated, spherical surfaces. * Mapping of fMRI volumes onto surfaces. * Surface reconstruction from anatomical MRI volumes using the SureFit algorithm. * Surface reconstruction from contours. * Surface-based registration. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tk (computing)
Tk is a free and open-source, cross-platform widget toolkit that provides a library of basic elements of GUI widgets for building a graphical user interface (GUI) in many programming languages. Tk provides a number of widgets commonly needed to develop desktop applications, such as button, menu, canvas, text, frame, label, etc. Tk has been ported to run on most flavors of Linux, Mac OS, Unix, and Microsoft Windows. Like Tcl, Tk supports Unicode within the Basic Multilingual Plane, but it has not yet been extended to handle the current extended full Unicode (e.g., UTF-16 from UCS-2 that Tk supports). Tk was designed to be extended, and a wide range of extensions are available that offer new widgets or other capabilities. Since Tcl/Tk 8, it offers "native look and feel" (for instance, menus and buttons are displayed in the manner of "native" software for any given platform). Highlights of version 8.5 include a new theming engine, originally called Tk Tile, but it is now general ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FMRIB Software Library
The FMRIB Software Library, abbreviated FSL, is a software library containing image analysis and statistical tools for functional, structural and diffusion MRI brain imaging data. FSL is available as both precompiled binaries and source code for Apple and PC (Linux) computers. It is freely available for non-commercial use. FSL Functionality History and development FSL is written mainly by members of the FMRIB (Functional Magnetic Resonance Imaging of the Brain) Analysis Group, Oxford University, UK. The first release of FSL was in 2000; there has been approximately one major new release each year to date. The FMRIB Analysis Group is primarily funded by the Wellcome Trust and the UK EPSRC and MRC Research Councils. See also * AFNI * FreeSurfer * SPM * Neuroimaging Neuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy hum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
General Linear Model
The general linear model or general multivariate regression model is a compact way of simultaneously writing several multiple linear regression models. In that sense it is not a separate statistical linear model. The various multiple linear regression models may be compactly written as : \mathbf = \mathbf\mathbf + \mathbf, where Y is a matrix with series of multivariate measurements (each column being a set of measurements on one of the dependent variables), X is a matrix of observations on independent variables that might be a design matrix (each column being a set of observations on one of the independent variables), B is a matrix containing parameters that are usually to be estimated and U is a matrix containing errors (noise). The errors are usually assumed to be uncorrelated across measurements, and follow a multivariate normal distribution. If the errors do not follow a multivariate normal distribution, generalized linear models may be used to relax assumptions about Y and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
