Frederick W. Alt
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Frederick W. Alt
Frederick W. Alt is an American geneticist. He is a member of the Immunology section of the National Academy of Sciences and a Charles A. Janeway Professor of Pediatrics, and Professor of Genetics at Harvard Medical School. He is the Director of the Program in Cellular and Molecular Medicine at the Boston Children's Hospital. He is a Howard Hughes Medical Institute investigator, since 1987. Career Alt completed his undergraduate studies at Brandeis University, graduating in 1971. He then went on to earn a Ph.D. in Biology from Stanford University in 1977 while under the research direction of Robert Schimke. He performed his postdoctoral work in David Baltimore's laboratory at Massachusetts Institute of Technology (MIT). From 1982 to 1991 he was on the faculty at Columbia University and then moved to Harvard Medical School. Alt's research interest is in maintenance of genome stability in cells of the mammalian immunological system, particularly antigen receptor variable regio ...
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Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ...
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B Lymphocytes
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. B cells produce antibody molecules which may be either secreted or inserted into the plasma membrane where they serve as a part of B-cell receptors. When a naïve or memory B cell is activated by an antigen, it proliferates and differentiates into an antibody-secreting effector cell, known as a plasmablast or plasma cell. Additionally, B cells present antigens (they are also classified as professional antigen-presenting cells (APCs)) and secrete cytokines. In mammals, B cells mature in the bone marrow, which is at the core of most bones. In birds, B cells mature in the bursa of Fabricius, a lymphoid organ where they were first discovered by Chang and Glick, which is why the 'B' stands for bursa and not bone marrow as commonly believed. B cells, unlike the other two classes of lymphocytes, T cells and na ...
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Paul Ehrlich And Ludwig Darmstaedter Prize
The Paul Ehrlich and Ludwig Darmstaedter Prize is an annual award bestowed by the since 1952 for investigations in medicine. It carries a prize money of 120,000 Euro. The prize awarding ceremony is traditionally held on March 14, the birthday of Nobel laureate Paul Ehrlich, in the St. Paul's Church, Frankfurt am Main. Researchers from worldwide are awarded in the following fields of medicine: Immunology, Cancer research, Haematology, Microbiology and experimental and clinical Chemotherapy. It is one of the highest endowed and internationally most distinguished awards in medicine in Germany. Some of the prize winners were later awarded the Nobel Prize. List of winners * 1952 ** , Tübingen ** , Nonnenhorn * 1953 ** Adolf Butenandt, Munich * 1954 ** Ernst Boris Chain, London * 1956 ** Gerhard Domagk, Elberfeld * 1958 ** Richard Johann Kuhn, Heidelberg * 1960 ** Felix Haurowitz, Bloomington * 1961 ** Albert Hewett Coons, Boston ** , Langen ** Örjan Ouchterlony, Gothenburg * ...
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National Foundation For Cancer Research
National Foundation for Cancer Research (NFCR) is an American nonprofit organization founded in 1973. It provides funds to cancer scientists and researchers, with the ultimate goal of a cure for cancer. Awards The Szent-Györgyi Prize for Progress in Cancer Research, established by the NFCR and named in honor of Albert Szent-Györgyi Albert Imre Szent-Györgyi de Nagyrápolt ( hu, nagyrápolti Szent-Györgyi Albert Imre; September 16, 1893 – October 22, 1986) was a Hungarian biochemist who won the Nobel Prize in Physiology or Medicine in 1937. He is credited with fi ..., Nobel Laureate and co-founder of NFCR, has been awarded annually since 2006 to outstanding researchers whose scientific achievements have expanded the understanding of cancer and whose vision has moved cancer research in new directions. The Szent-Györgyi Prize honors researchers whose discoveries have made possible new approaches to preventing, diagnosing and/or treating cancer. References Extern ...
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Szent-Györgyi Prize For Progress In Cancer Research
The Szent-Györgyi Prize for Progress in Cancer Research, established by National Foundation for Cancer Research (NFCR) and named in honor of Albert Szent-Györgyi, Nobel Laureate and co-founder of NFCR, has been awarded annually since 2006 to outstanding researchers whose scientific achievements have expanded the understanding of cancer and whose vision has moved cancer research in new directions. The Szent-Györgyi Prize honors researchers whose discoveries have made possible new approaches to preventing, diagnosing and/or treating cancer. The Prize recipient is honored at a formal dinner and award ceremony and receives a $25,000 cash prize. In addition, the recipient leads the next "Szent-Györgyi Prize Committee" as honorary chairman. The Szent-Györgyi Prize is named in honor of Albert Szent-Györgyi, M.D., Ph.D. was a pioneer who challenged the conventional thinking of the day to pursue his novel ideas. After winning the Nobel Prize for his study on vitamin C and cell respir ...
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Rosenstiel Award
The Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research is awarded by Brandeis University. It was established in 1971 "as an expression of the conviction that educational institutions have an important role to play in the encouragement and development of basic science as it applies to medicine". Medals are presented annually at Brandeis University on the basis of recommendations of a panel of scientists selected by the Rosenstiel Basic Medical Sciences Research Center. Awards are given to scientists for recent discoveries of "particular originality" and "importance to basic medical research". A $30,000 prize and a medallion accompanies each award. The Rosenstiel Basic Medical Sciences Research Center, named after Lewis Solon Rosenstiel, was established in 1968, carrying out research in basic medical science. Recipients SourceBrandeis University *2022 Christine Holt and Erin Schuman, for their pioneering work that shed light on the role of local protei ...
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Cancer Research Institute
The Cancer Research Institute (CRI) is a US non-profit organization funding cancer research and based in New York City. They were founded in 1953 to develop immunologically-based treatments for cancer, and despite their name are a funding body for research rather than a research institute themselves, working with other institutes and organizations. It was founded by Helen Coley Nauts and Oliver R. Grace with a $2,000 grant from Nelson Rockefeller. CRI was created in honor of Nauts' father, William Coley (1862–1936), an American orthopedic surgeon and a pioneer of cancer immunotherapy. Like Dr. Coley, the Institute focuses on immunological treatments for cancer, rather than traditional treatments, such as chemotherapy and surgery. The organization offers research grants to students, postdoctoral fellows, and investigators at medical research institutions throughout the world. It also funds clinical trials testing promising immunotherapies in a variety of cancer types and conv ...
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William B
William is a male given name of Germanic origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of England in 1066,All Things William"Meaning & Origin of the Name"/ref> and remained so throughout the Middle Ages and into the modern era. It is sometimes abbreviated "Wm." Shortened familiar versions in English include Will, Wills, Willy, Willie, Bill, and Billy. A common Irish form is Liam. Scottish diminutives include Wull, Willie or Wullie (as in Oor Wullie or the play ''Douglas''). Female forms are Willa, Willemina, Wilma and Wilhelmina. Etymology William is related to the given name ''Wilhelm'' (cf. Proto-Germanic ᚹᛁᛚᛃᚨᚺᛖᛚᛗᚨᛉ, ''*Wiljahelmaz'' > German ''Wilhelm'' and Old Norse ᚢᛁᛚᛋᛅᚼᛅᛚᛘᛅᛋ, ''Vilhjálmr''). By regular sound changes, the native, inherited English form of the name should b ...
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Novartis Prize For Basic Immunology
The Novartis Prizes for Immunology were established in 1990 by Sandoz to honour outstanding research in immunology, and expanded to their current form in 1992. Prizes for basic and clinical immunology are awarded every 3 years. A special prize was awarded in 2004. Sandoz Prize for Immunology * 1990 Max Cooper, Jacques Miller Novartis Prize for Basic Immunology * 2016 John Kappler, Philippa Marrack, Harald von Boehmer * 2013 , * 2010 * 2007 Fred Alt, Klaus Rajewsky, * 2004 Ralph Steinman * 2001 Klas Kärre, , * 1998 Tak Mak * 1995 Melvin Cohn, , Avrion Mitchison, David Talmage * 1992 Jack Strominger Novartis Prize for Clinical Immunology * 2016 Zelig Eshhar, Carl June, Steven Rosenberg * 2013 James Allison * 2010 Charles Dinarello, Jürg Tschopp * 2007 , Doug Lowy, Ian Frazer * 2004 Hugh McDevitt * 2001 Alain Fischer * 1998 Barry Bloom, George Bellamy Mackaness, Andrew McMichael * 1995 Robert Schwartz, Thierry Boon * 1992 Tadamitsu Kishimoto, Toshio Hirano Special Novart ...
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Robert J
The name Robert is an ancient Germanic given name, from Proto-Germanic "fame" and "bright" (''Hrōþiberhtaz''). Compare Old Dutch ''Robrecht'' and Old High German ''Hrodebert'' (a compound of '' Hruod'' ( non, Hróðr) "fame, glory, honour, praise, renown" and ''berht'' "bright, light, shining"). It is the second most frequently used given name of ancient Germanic origin. It is also in use as a surname. Another commonly used form of the name is Rupert. After becoming widely used in Continental Europe it entered England in its Old French form ''Robert'', where an Old English cognate form (''Hrēodbēorht'', ''Hrodberht'', ''Hrēodbēorð'', ''Hrœdbœrð'', ''Hrœdberð'', ''Hrōðberχtŕ'') had existed before the Norman Conquest. The feminine version is Roberta. The Italian, Portuguese, and Spanish form is Roberto. Robert is also a common name in many Germanic languages, including English, German, Dutch, Norwegian, Swedish, Scots, Danish, and Icelandic. It can be use ...
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American Association Of Immunologists
The American Association of Immunologists (AAI) is an international scientific society dedicated to furthering the study of immunology. AAI provides its members with a variety of platforms in which to exchange ideas and present the latest immunological research, including the AAI annual meeting and ''The Journal of Immunology''. In 2017, AAI launched an open-access journal, ''ImmunoHorizons''. AAI is a founding member society of the Federation of American Societies for Experimental Biology (FASEB). Mission The American Association of Immunologists is an association of professionally trained scientists from all over the world dedicated to advancing the knowledge of immunology and its related disciplines, fostering the interchange of ideas and information among investigators, and addressing the potential integration of immunologic principles into clinical practice. AAI serves its members by providing a center for the dissemination of information relevant to the field and its practi ...
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National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. The NCI conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship. NCI is the oldest and has the largest budget and research program of the 27 institutes and centers of the NIH ($6.9 billion in 2020). It fulfills the majority of its mission via an extramural program that provides grants for cancer research. Additionally, the National Cancer Institute has intramural research programs in Bethesda, Maryland, and at the Frederick National Laboratory for Cancer Research at Fort Detrick in Frederick, Maryland. The NCI receives more than in funding each ...
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