Frank Winder
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Frank Winder
Frank Winder (Francis Gerard Augustine Winder; 14 April 1928 – 30 December 2007, in Dublin) was an Irish professor of biochemistry, a naturalist, and one of Ireland's leading rock climbing, rock climbers in the 1950s and 1960s. Scientific career Winder (surname), Winder received his early education at Belvedere College, and developed an early interest in botany and zoology, cycling around the Irish countryside looking for interesting specimens. In 1945 he entered University College Dublin (UCD) to study science and came to the attention of Arthur Wilson Stelfox, Arthur Stelfox of the Natural History Museum (Ireland), Natural History Museum. Stelfox introduced Winder to entomologist Philip Graves, who promptly sent the 18-year-old Winder off to the mountains of County Kerry, Kerry in search of a rare butterfly, but Winder returned with a specimen of a dragonfly, Cordulia aenea, which was previously unknown in Ireland. While climbing a steep gully on Knocknagantee in Kerry in se ...
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Frank Winder
Frank Winder (Francis Gerard Augustine Winder; 14 April 1928 – 30 December 2007, in Dublin) was an Irish professor of biochemistry, a naturalist, and one of Ireland's leading rock climbing, rock climbers in the 1950s and 1960s. Scientific career Winder (surname), Winder received his early education at Belvedere College, and developed an early interest in botany and zoology, cycling around the Irish countryside looking for interesting specimens. In 1945 he entered University College Dublin (UCD) to study science and came to the attention of Arthur Wilson Stelfox, Arthur Stelfox of the Natural History Museum (Ireland), Natural History Museum. Stelfox introduced Winder to entomologist Philip Graves, who promptly sent the 18-year-old Winder off to the mountains of County Kerry, Kerry in search of a rare butterfly, but Winder returned with a specimen of a dragonfly, Cordulia aenea, which was previously unknown in Ireland. While climbing a steep gully on Knocknagantee in Kerry in se ...
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Cordulia Aenea
The downy emerald (''Cordulia aenea'') is a species of dragonfly. It is metallic green and bronze in color, and its thorax is coated with fine hairs, hence its name. Like most other emeralds, the downy emerald has bright shiny green eyes. Adults are around 5 cm in length, and are in flight from May through July each year. This species lives in woodlands near lakes and ponds; like other dragonflies, it lays eggs in water and its larvae are aquatic. It is distributed throughout most of Europe. Although it has been eliminated from some of its historic native area in Great Britain Great Britain is an island in the North Atlantic Ocean off the northwest coast of continental Europe. With an area of , it is the largest of the British Isles, the largest European island and the ninth-largest island in the world. It i ... due to habitat loss, dense populations of the downy emerald can still be found there in spots where its ideal habitat remains. After the downy emerald ...
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Think-tank
A think tank, or policy institute, is a research institute that performs research and advocacy concerning topics such as social policy, political strategy, economics, military, technology, and culture. Most think tanks are non-governmental organizations, but some are semi-autonomous agencies within government or are associated with particular political parties, businesses or the military. Think-tank funding often includes a combination of donations from very wealthy people and those not so wealthy, with many also accepting government grants. Think tanks publish articles and studies, and even draft legislation on particular matters of policy or society. This information is then used by governments, businesses, media organizations, social movements or other interest groups. Think tanks range from those associated with highly academic or scholarly activities to those that are overtly ideological and pushing for particular policies, with a wide range among them in terms of the qual ...
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Vojo Deretic
Vojo Deretic, is distinguished professor and chair of the Department of Molecular Genetics and Microbiology at the University of New Mexico School of Medicine. Deretic was the founding director of the Autophagy, Inflammation and Metabolism (AIM) Center of Biomedical Research Excellence. The AIM center promotes autophagy research nationally and internationally. Education Vojo Peter Deretic received his undergraduate, graduate and postdoctoral education in Belgrade, Paris, and Chicago. He was a faculty member at the University of Texas, University of Michigan, and joined University of New Mexico Health Sciences Center in 2001. Career and research Vojo Deretic's main contributions to science come from studies by his team on the role of autophagy in infection and immunity. Autophagy is a cytoplasmic pathway with quality control and metabolic roles. Autophagic removal of damaged or surplus organelles, has been implicated in cancer, neurodegeneration such as Alzheimer's disease, ...
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Isoniazid
Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. For latent tuberculosis it is often used by itself. It may also be used for atypical types of mycobacteria, such as '' M. avium'', '' M. kansasii'', and '' M. xenopi''. It is usually taken by mouth but may be used by injection into muscle. Common side effects include increased blood levels of liver enzymes and numbness in the hands and feet. Serious side effects may include liver inflammation and acute liver failure. It is unclear if use during pregnancy is safe for the baby. Use during breastfeeding is likely safe. Pyridoxine may be given to reduce the risk of side effects. Isoniazid works in part by disrupting the formation of the bacteria's cell wall which results in cell death. Isoniazid was first made in 1952. It is on the World ...
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Leprosy
Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria ''Mycobacterium leprae'' or ''Mycobacterium lepromatosis''. Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. This nerve damage may result in a lack of ability to feel pain, which can lead to the loss of parts of a person's extremities from repeated injuries or infection through unnoticed wounds. An infected person may also experience muscle weakness and poor eyesight. Leprosy symptoms may begin within one year, but, for some people, symptoms may take 20 years or more to occur. Leprosy is spread between people, although extensive contact is necessary. Leprosy has a low pathogenicity, and 95% of people who contract ''M. leprae'' do not develop the disease. Spread is thought to occur through a cough or contact with fluid from the nose of a person infected by leprosy. Genetic factors and immune function play a role in how easily a person catches the disease. Lepro ...
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Phenazine
Phenazine is an organic compound with the formula (C6H4)2N2. It is a dibenzo annulation, annulated pyrazine, and the parent substance of many dyestuffs, such as the toluylene red, indulines, and safranines (and the closely related eurhodines). Phenazine crystallizes in yellow needles, which are only sparingly soluble in ethanol, alcohol. Sulfuric acid dissolves it, forming a deep-red solution. Synthesis Classically phenazine are prepared by the reaction of nitrobenzene and aniline in the Wohl-Aue reaction. Other methods include: * pyrolysis of the barium salt (chemistry), salt of azobenzoate * oxidation of aniline with lead oxide * oxidation of dihydrophenazine, which is prepared by heating pyrocatechin with o-phenylenediamine. * oxidation of ortho-aminodiphenylamine with lead peroxide. Derivatives * The more complex phenazines, such as the naphthophenazines, naphthazines, and naphthotolazines, may be prepared by condensing Toluidine, ortho-diamines with quinone, ortho-quinones or ...
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Vincent Barry
Vincent Christopher Barry (1908–1975) was a scientist and researcher from Ireland. He is known for leading the team which developed the anti-leprosy drug clofazimine. Early life and education Barry was born in Sunday's Well, Cork. He was the youngest of 11 children. After secondary school in the North Monastery he earned a scholarship to University College Dublin (UCD) where he obtained a first class honours degree in organic chemistry. After graduation, Barry moved to NUI Galway where he worked under Professor Thomas Dillon. Research In 1943, Barry returned to Dublin to work for the Medical Research Council. Barry worked with The Leprosy Mission in Zimbabwe and India to develop drugs against tuberculosis and leprosy. He led a team of scientists at Trinity College, Dublin to discover the anti-leprosy drug clofazimine. In 1969 he was awarded the Boyle Medal of the Royal Dublin Society. Barry and his team were awarded the 1980 UNESCO Science Prize for their work. Personal ...
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Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ...
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals (signal transduction). The development of therapies with specific molecular or genetic targets, wh ...
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Trinity College Dublin
, name_Latin = Collegium Sanctae et Individuae Trinitatis Reginae Elizabethae juxta Dublin , motto = ''Perpetuis futuris temporibus duraturam'' (Latin) , motto_lang = la , motto_English = It will last into endless future times , founder = Queen Elizabeth I , established = , named_for = Trinity, The Holy Trinity.The Trinity was the patron of The Dublin Guild Merchant, primary instigators of the foundation of the University, the arms of which guild are also similar to those of the College. , previous_names = , status = , architect = , architectural_style =Neoclassical architecture , colours = , gender = , sister_colleges = St. John's College, CambridgeOriel College, Oxford , freshman_dorm = , head_label = , head = , master = , vice_head_label = , vice_head = , warden ...
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Health Research Board
The Health Research Board (HRB) is a government agency responsible for funding, co-ordination, and oversight of medical research in Ireland. History In 1986, the Government of Ireland amalgamated the Medical Research Council of Ireland and the Medico-Social Research Board to establish the HRB under the Health (Corporate Bodies) Act 1961 and statutory instrument In many countries, a statutory instrument is a form of delegated legislation. United Kingdom Statutory instruments are the principal form of delegated or secondary legislation in the United Kingdom. National government Statutory instrument ... 279 of 1986. The HRB's original headquarters was at 73 Lower Baggot Street, Dublin 2. In July 2014, the board relocated to Grattan House, 67-72 Lower Mount Street, Dublin 2. Chairs of the HRB * Dr WA Watts 1987 - 1989 * Professor MX FitzGerald 1990 - 1997 * Professor MB Murphy 1997 - 2002 * Professor Hugh R. Brady 2002 - 2003 * Professor D Fitzgerald 2003 - 2007 * Mr Reg Shaw ...
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