Frank Gotch (MD)
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Frank Gotch (MD)
Frank A. Gotch (August 27, 1926 - February 18, 2017) was an American physician known for his work in renal dialysis Kidney dialysis (from Greek , , 'dissolution'; from , , 'through', and , , 'loosening or splitting') is the process of removing excess water, solutes, and toxins from the blood in people whose kidneys can no longer perform these functions nat ... adequacy, specifically the development of Kt/V and standardized Kt/V. He was an Associate Professor of Medicine at the University of California, San Francisco. Gotch was a consultant to the Renal Research Institute in New York and was Associate Professor of Medicine at UCSF. Gotch worked in clinical dialysis and dialysis research, particularly quantification of therapy, for over 30 years. He chaired the NIH Hemodialyzer evaluation Study Group which sets standards for dialyzer performance in 1972 and the National NIH conference on Adequacy of Hemodialysis in 1975. He served on the planning committee and as kine ...
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Humboldt, Iowa
Humboldt is a city in Humboldt County, Iowa, United States. The population was 4,792 at the time of the 2020 census, gaining 340 people over the 2000 total. History Frank A. Gotch Park (just south of present-day Humboldt and Dakota City) was a location of prehistoric and some Dakota Indian villages near where the two forks of the Des Moines River meet. During westward expansion in the 1800s, this area is thought to be the location of a fort/trading post called Fort Confederation. According to Federal records in 1825, permission was granted to build the fort to trade with the Ihanktonwan Dakota (Yankton Sioux) Indians. Information about the exact details of the fort are unclear, such as if American or French Canadian or Metis traders built it, bringing up many questions about this fort. The founder of modern Humboldt, Stephen Harris Taft, laid out the plans for Springvale, the original name of the town, in 1863. It was named Springvale because of the several natural springs fo ...
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San Francisco, California
San Francisco (; Spanish for " Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the fourth most populous in California and 17th most populous in the United States, with 815,201 residents as of 2021. It covers a land area of , at the end of the San Francisco Peninsula, making it the second most densely populated large U.S. city after New York City, and the fifth most densely populated U.S. county, behind only four of the five New York City boroughs. Among the 91 U.S. cities proper with over 250,000 residents, San Francisco was ranked first by per capita income (at $160,749) and sixth by aggregate income as of 2021. Colloquial nicknames for San Francisco include ''SF'', ''San Fran'', ''The '', ''Frisco'', and ''Baghdad by the Bay''. San Francisco and the surrounding San Francisco Bay Area are a global center of economic activity and the arts and sciences, spurred ...
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University Of California, Berkeley
The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant university and the founding campus of the University of California system. Its fourteen colleges and schools offer over 350 degree programs and enroll some 31,800 undergraduate and 13,200 graduate students. Berkeley ranks among the world's top universities. A founding member of the Association of American Universities, Berkeley hosts many leading research institutes dedicated to science, engineering, and mathematics. The university founded and maintains close relationships with three national laboratories at Berkeley, Livermore and Los Alamos, and has played a prominent role in many scientific advances, from the Manhattan Project and the discovery of 16 chemical elements to breakthroughs in computer science and genomics. Berkeley is ...
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University Of California, San Francisco
The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It conducts research and teaching in medical and biological sciences. UCSF was founded as Toland Medical College in 1864. in 1873, it became affiliated with the University of California as its Medical Department. In the same year, it incorporated the California College of Pharmacy and in 1881 it established a dentistry school. Its facilities were located in both Berkeley and San Francisco. In 1964, the school gained full administrative independence as a campus of the UC system, headed by its own chancellor, and in 1970 it gained its current name. Historically based at Parnassus Heights with satellite facilities throughout the city, UCSF developed a second major campus in the newly redeveloped Mission Bay district in the early 2000s. '' U.S. N ...
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Physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ...
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Renal Dialysis
Kidney dialysis (from Greek , , 'dissolution'; from , , 'through', and , , 'loosening or splitting') is the process of removing excess water, solutes, and toxins from the blood in people whose kidneys can no longer perform these functions naturally. This is referred to as renal replacement therapy. The first successful dialysis was performed in 1943. Dialysis may need to be initiated when there is a sudden rapid loss of kidney function, known as acute kidney injury (previously called acute renal failure), or when a gradual decline in kidney function, chronic kidney disease, reaches stage 5. Stage 5 chronic renal failure is reached when the glomerular filtration rate is 10–15% of normal, creatinine clearance is less than 10 mL per minute and uremia is present. Dialysis is used as a temporary measure in either acute kidney injury or in those awaiting kidney transplant and as a permanent measure in those for whom a transplant is not indicated or not possible.Pendse S, Sin ...
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Kt/V
In medicine, ''Kt/V'' is a number used to quantify hemodialysis and peritoneal dialysis treatment adequacy. *''K'' – dialyzer clearance of urea *''t'' – dialysis time *''V'' – volume of distribution of urea, approximately equal to patient's total body water In the context of hemodialysis, Kt/V is a pseudo-dimensionless number; it is dependent on the pre- and post-dialysis concentration (see below). It is ''not'' the product of ''K'' and ''t'' divided by ''V'', as would be the case in a true dimensionless number. In peritoneal dialysis, it isn't dimensionless at all. It was developed by Frank Gotch and John Sargent as a way for measuring the dose of dialysis when they analyzed the data from the National Cooperative Dialysis Study. In hemodialysis the US National Kidney Foundation ''Kt''/''V'' target is ≥ 1.3, so that one can be sure that the delivered dose is at least 1.2. In peritoneal dialysis the target is ≥ 1.7/week. Despite the name, ''Kt''/''V'' is quit ...
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Standardized Kt/V
Standardized Kt/V, also std Kt/V, is a way of measuring (renal) dialysis adequacy. It was developed by Frank Gotch and is used in the United States to measure dialysis. Despite the name, it is quite different from Kt/V. In theory, both peritoneal dialysis and hemodialysis can be quantified with std Kt/V. Derivation Standardized Kt/V is motivated by the steady state solution of the mass transfer equation often used to approximate kidney function (equation ''1''), which is also used to define clearance. :V \frac = -K \cdot C + \dot \qquad(1) where *\dot is the mass generation rate of the substance - assumed to be a constant, i.e. not a function of time (equal to zero for foreign substances/drugs) mol/minor ol/s*t is dialysis time inor *V is the volume of distribution (total body water) or 3*K is the clearance L/minor 3/s*C is the concentration mol/Lor ol/m3(in the United States often g/mL From the above definitions it follows that \frac is the first derivative of conc ...
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Professor
Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors are usually experts in their field and teachers of the highest rank. In most systems of List of academic ranks, academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word "professor" is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well. This usage would be considered incorrect among other academic communities. However, the otherwise unqualified title "Professor" designated with a capital let ...
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Medicine
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, o ...
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1926 Births
Events January * January 3 – Theodoros Pangalos (general), Theodoros Pangalos declares himself dictator in Greece. * January 8 **Abdul-Aziz ibn Saud is crowned King of Kingdom of Hejaz, Hejaz. ** Bảo Đại, Crown Prince Nguyễn Phúc Vĩnh Thuy ascends the throne, the last monarch of Vietnam. * January 12 – Freeman Gosden and Charles Correll premiere their radio program ''Sam 'n' Henry'', in which the two white performers portray two black characters from Harlem looking to strike it rich in the big city (it is a precursor to Gosden and Correll's more popular later program, ''Amos 'n' Andy''). * January 16 – A BBC comic radio play broadcast by Ronald Knox, about a workers' revolution, causes a panic in London. * January 21 – The Belgian Parliament accepts the Locarno Treaties. * January 26 – Scottish inventor John Logie Baird demonstrates a mechanical television system at his London laboratory for members of the Royal Institution and a report ...
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2017 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day The following pages, corresponding to the Gregorian calendar, list the historical events, births, deaths, and holidays and observances of the specified day of the year: Footnotes See also * Leap year * List of calendars * List of non-standard ... * Deaths by year {{DEFAULTSORT:deaths by year ...
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