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Fourth Ventricle
The fourth ventricle is one of the four connected fluid-filled cavities within the human brain. These cavities, known collectively as the ventricular system, consist of the left and right lateral ventricles, the third ventricle, and the fourth ventricle. The fourth ventricle extends from the cerebral aqueduct (''aqueduct of Sylvius'') to the obex, and is filled with cerebrospinal fluid (CSF). The fourth ventricle has a characteristic diamond shape in cross-sections of the human brain. It is located within the pons or in the upper part of the medulla oblongata. CSF entering the fourth ventricle through the cerebral aqueduct can exit to the subarachnoid space of the spinal cord through two lateral apertures and a single, midline median aperture. Boundaries The fourth ventricle has a roof at its ''upper'' (posterior) surface and a floor at its ''lower'' (anterior) surface, and side walls formed by the cerebellar peduncles (nerve bundles joining the structure on the posterior si ...
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Human Brain
The human brain is the central organ (anatomy), organ of the human nervous system, and with the spinal cord makes up the central nervous system. The brain consists of the cerebrum, the brainstem and the cerebellum. It controls most of the activities of the human body, body, processing, integrating, and coordinating the information it receives from the Sensory nervous system, sense organs, and making decisions as to the instructions sent to the rest of the body. The brain is contained in, and protected by, the neurocranium, skull bones of the human head, head. The cerebrum, the largest part of the human brain, consists of two cerebral hemispheres. Each hemisphere has an inner core composed of white matter, and an outer surface – the cerebral cortex – composed of grey matter. The cortex has an outer layer, the neocortex, and an inner allocortex. The neocortex is made up of six Cerebral cortex#Layers of neocortex, neuronal layers, while the allocortex has three or four. Each ...
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Foramen Magnum
The foramen magnum ( la, great hole) is a large, oval-shaped opening in the occipital bone of the skull. It is one of the several oval or circular openings (foramina) in the base of the skull. The spinal cord, an extension of the medulla oblongata, passes through the foramen magnum as it exits the cranial cavity. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the vertebral arteries, the anterior and posterior spinal arteries, the tectorial membranes and alar ligaments. It also transmits the accessory nerve into the skull. The foramen magnum is a very important feature in bipedal mammals. One of the attributes of a biped's foramen magnum is a forward shift of the anterior border of the cerebellar tentorium; this is caused by the shortening of the cranial base. Studies on the foramen magnum position have shown a connection to the functional influences of both posture and locomotion. The forward shift of the foramen magn ...
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Noradrenaline
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as both a hormone and neurotransmitter. The name "noradrenaline" (from Latin '' ad'', "near", and '' ren'', "kidney") is more commonly used in the United Kingdom, whereas "norepinephrine" (from Ancient Greek ἐπῐ́ (''epí''), "upon", and νεφρός (''nephrós''), "kidney") is usually preferred in the United States. "Norepinephrine" is also the international nonproprietary name given to the drug. Regardless of which name is used for the substance itself, parts of the body that produce or are affected by it are referred to as noradrenergic. The general function of norepinephrine is to mobilize the brain and body for action. Norepinephrine release is lowest during sleep, rises during wakefulness, and reaches much higher levels during situations of stress or danger, in the so-called fight-or-flight response. In the ...
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Locus Coeruleus
The locus coeruleus () (LC), also spelled locus caeruleus or locus ceruleus, is a nucleus in the pons of the brainstem involved with physiological responses to stress and panic. It is a part of the reticular activating system. The locus coeruleus, which in Latin means "blue spot", is the principal site for brain synthesis of norepinephrine (noradrenaline). The locus coeruleus and the areas of the body affected by the norepinephrine it produces are described collectively as the locus coeruleus-noradrenergic system or LC-NA system. Norepinephrine may also be released directly into the blood from the adrenal medulla. Anatomy The locus coeruleus (LC) is located in the posterior area of the rostral pons in the lateral floor of the fourth ventricle. It is composed of mostly medium-size neurons. Melanin granules inside the neurons of the LC contribute to its blue colour. Thus, it is also known as the nucleus pigmentosus pontis, meaning "heavily pigmented nucleus of the pons." ...
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Medial Eminence Of Floor Of Fourth Ventricle
In the human brain, the rhomboid fossa is divided into symmetrical halves by a median sulcus which reaches from the upper to the lower angles of the fossa and is deeper below than above. On either side of this sulcus is an elevation, the medial eminence, bounded laterally by a sulcus, the sulcus limitans. In the superior part of the fossa the medial eminence has a width equal to that of the corresponding half of the fossa, but opposite the superior fovea it forms an elongated swelling, the ''colliculus facialis'', which overlies the nucleus of the abducent nerve, and is, in part at least, produced by the internal genu of the facial nerve The facial nerve, also known as the seventh cranial nerve, cranial nerve VII, or simply CN VII, is a cranial nerve that emerges from the pons of the brainstem, controls the muscles of facial expression, and functions in the conveyance of taste .... References External links * https://web.archive.org/web/20081224022115/http://isc.temple.ed ...
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Sulcus Limitans
The sulcus limitans is found in the fourth ventricle of the brain. It separates the cranial nerve motor nuclei (medial) from the sensory nuclei (lateral).Nolte, John. The Human Brain 6th ed. p.685. Mosby Inc. It can also be located by searching laterally from the medial eminence In the human brain, the rhomboid fossa is divided into symmetrical halves by a median sulcus which reaches from the upper to the lower angles of the fossa and is deeper below than above. On either side of this sulcus is an elevation, the medial em .... It is parallel to the median sulcus. References External links Diagram of the sulcus limitansSectional Atlas: Pons at the Abducens Nucleus - Facial Colliculus Brainstem {{Neuroanatomy-stub ...
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Rhomboid Fossa
The rhomboid fossa is a rhombus-shaped depression that is the anterior part of the fourth ventricle. Its anterior wall, formed by the back of the pons and the medulla oblongata, constitutes the floor of the fourth ventricle. It is covered by a thin layer of grey matter continuous with that of the spinal cord; superficial to this is a thin lamina of neuroglia which constitutes the ependyma of the ventricle and supports a layer of ciliated epithelium. Parts The fossa consists of three parts, superior, intermediate, and inferior: ;The superior part :The superior part is triangular in shape and limited laterally by the superior cerebellar peduncle; its apex, directed upward, is continuous with the cerebral aqueduct; its base is represented by an imaginary line at the level of the upper ends of the superior foveae. ;The intermediate part :The intermediate part extends from this level to that of the horizontal portions of the taeniae of the ventricle; it is narrow above where it is ...
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Fastigial Nucleus
The fastigial nucleus is located in the cerebellum. It is one of the four deep cerebellar nuclei (the others being the nucleus dentatus, nucleus emboliformis and nucleus globosus), and is grey matter embedded in the white matter of the cerebellum. It refers specifically to the concentration of gray matter nearest to the middle line at the anterior end of the superior vermis, and immediately over the roof of the fourth ventricle (the peak of which is called the ''fastigium''), from which it is separated by a thin layer of white matter. It is smaller than the nucleus dentatus, but somewhat larger than the nucleus emboliformis and nucleus globosus. Although it is one dense mass, it is made up of two sections: the rostral fastigial nucleus and the caudal fastigial nucleus. Structure The Purkinje cells of the cerebellar cortex project into the deep cerebellar nuclei and inhibit the excitatory output system via GABAergic synapses. The fastigial nucleus receives its input fr ...
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Lateral Aperture
The lateral aperture is a paired structure in human anatomy. It is an opening in each lateral extremity of the lateral recess of the fourth ventricle of the human brain, which also has a single median aperture. The two lateral apertures provide a conduit for cerebrospinal fluid to flow from the brain's ventricular system into the subarachnoid space; specifically into the pontocerebellar cistern at the cerebellopontine angle. The structure is also called the lateral aperture of the fourth ventricle or the foramen of Luschka after anatomist Hubert von Luschka. Gross total resection of tumours that extend through foramen of Lushka is sometimes not possible due to bradycardia Bradycardia (also sinus bradycardia) is a slow resting heart rate, commonly under 60 beats per minute (BPM) as determined by an electrocardiogram. It is considered to be a normal heart rate during sleep, in young and healthy or elderly adults, .... References Ventricular system {{Neuroa ...
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Cisterna Magna
The cisterna magna (or cerebellomedullar cistern) is one of three principal openings in the subarachnoid space between the arachnoid and pia mater layers of the meninges surrounding the brain. The openings are collectively referred to as the subarachnoid cisterns. The cisterna magna is located between the cerebellum and the dorsal surface of the medulla oblongata. Cerebrospinal fluid produced in the fourth ventricle drains into the cisterna magna via the lateral apertures and median aperture. The two other principal cisterns are the ''pontine cistern'' located between the pons and the medulla and the ''interpeduncular cistern'' located between the cerebral peduncles The cerebral peduncles are the two stalks that attach the cerebrum to the brainstem. They are structures at the front of the midbrain which arise from the ventral pons and contain the large ascending (sensory) and descending (motor) nerve tract .... While the most commonly used clinical method for obtaini ...
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Cerebellum
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cerebellum plays an important role in motor control. It may also be involved in some cognitive functions such as attention and language as well as emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in fine movement, equilibrium, posture, and motor learning in humans. Anatomically, the human cerebellum has the appearance of a separate structure attached to the ...
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Inferior Medullary Velum
The inferior medullary velum (posterior medullary velum) is a thin layer of white substance, prolonged from the white center of the cerebellum, above and on either side of the nodule; it forms the infero-posterior part of the fourth ventricle. Somewhat semilunar in shape, its convex edge is continuous with the white substance of the cerebellum, while its thin concave margin is apparently free; in reality, however, it is continuous with the epithelium of the ventricle, which is prolonged downward from the posterior medullary velum to the taeniae. See also * Superior medullary velum The superior medullary velum (anterior medullary velum) is a thin, transparent lamina of white matter, which stretches between the superior cerebellar peduncles; on the dorsal surface of its lower half the folia and lingula are prolonged. It fo ... References Neuroanatomy {{Portal bar, Anatomy ...
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