Familial Renal Disease In Animals
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Familial Renal Disease In Animals
Familial renal disease is an uncommon cause of kidney failure in dogs and cats. Most causes are breed-related (familial) and some are inherited. Some are congenital (present at birth). Renal dysplasia is a type of familial kidney disease characterized by abnormal cellular differentiation of kidney tissue. Dogs and cats with kidney disease caused by these diseases have the typical symptoms of kidney failure, including weight loss, loss of appetite, depression, and increased water consumption and urination. A list of familial kidney diseases by dog and cat breeds is found below. Familial renal disease in dogs Basenji Basenjis can be affected by a type of kidney tubular dysfunction similar to that of Fanconi syndrome in humans. Beagle Beagles can be affected by glomerular amyloidosis, which is deposition of amyloid in the kidney. Findings include protein in the urine. It does progress. Bull Terrier Bull Terriers can be affected by an inherited type of kidney disease c ...
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Kidney Failure
Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. Kidney failure is classified as either acute kidney failure, which develops rapidly and may resolve; and chronic kidney failure, which develops slowly and can often be irreversible. Symptoms may include leg swelling, feeling tired, vomiting, loss of appetite, and confusion. Complications of acute and chronic failure include uremia, high blood potassium, and volume overload. Complications of chronic failure also include heart disease, high blood pressure, and anemia. Causes of acute kidney failure include low blood pressure, blockage of the urinary tract, certain medications, muscle breakdown, and hemolytic uremic syndrome. Causes of chronic kidney failure include diabetes, high blood pressure, nephrotic syndrome, and polycystic kidney disease. Diagnosis of acute failure ...
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Renal Osteodystrophy
Renal osteodystrophy/adynamic bone disease is currently defined as an alteration of bone morphology in patients with chronic kidney disease (CKD). It is one measure of the skeletal component of the systemic disorder of chronic kidney disease-mineral and bone disorder (CKD-MBD). The term "renal osteodystrophy" was coined in 1943, 60 years after an association was identified between bone disease and kidney failure. The traditional types of renal osteodystrophy have been defined on the basis of turnover and mineralization as follows: 1) mild, slight increase in turnover and normal mineralization; 2) osteitis fibrosa, increased turnover and abnormal mineralization; 3) osteomalacia, decreased turnover and abnormal mineralization; 4) adynamic, decreased turnover and acellularity; and, 5) mixed, increased turnover with abnormal mineralization. A Kidney Disease: Improving Global Outcomes report has suggested that bone biopsies in patients with CKD should be characterized by determining bo ...
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Cholesterol
Cholesterol is any of a class of certain organic molecules called lipids. It is a sterol (or modified steroid), a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell membranes. When chemically isolated, it is a yellowish crystalline solid. Cholesterol also serves as a precursor for the biosynthesis of steroid hormones, bile acid and vitamin D. Cholesterol is the principal sterol synthesized by all animals. In vertebrates, hepatic cells typically produce the greatest amounts. It is absent among prokaryotes (bacteria and archaea), although there are some exceptions, such as '' Mycoplasma'', which require cholesterol for growth. François Poulletier de la Salle first identified cholesterol in solid form in gallstones in 1769. However, it was not until 1815 that chemist Michel Eugène Chevreul named the compound "cholesterine". Etymology The word "cholesterol" comes from the Ancient Greek ''chole-'' ...
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Rottweiler
The Rottweiler (, ) is a breed of domestic dog, regarded as medium-to-large or large. The dogs were known in German as , meaning Rottweil butchers' dogs, because their main use was to herd livestock and pull carts laden with butchered meat to market. This continued until the mid-19th century when railways replaced droving. Although still used to herd stock in many parts of the world, Rottweilers are now also used as search and rescue dogs, guard dogs, and police dogs.Adolf Pienkoss, ''The Rottweiler'', 3rd ed., Borken, Germany: Internationale Föderation der Rottweilerfreunde, 2008. History According to the FCI Standard, the Rottweiler is considered to be one of the oldest surviving dog breeds. Its origin goes back to Roman times. These dogs were kept as herder or driving dogs. They marched over the Alps with the Roman legions, protecting the humans and driving their cattle. In the region of Rottweil, these dogs met and mixed with the native dogs in a natural crossing. ...
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Norwegian Elkhound
The Norwegian Elkhound is one of the Northern Spitz-type breeds of dog and is the National Dog of Norway. The Elkhound has served as a hunter, guardian, herder, and defender. It is known for its courage in tracking and hunting elk and other large game, such as bears or wolves. The Norwegian Elkhound was first presented at a dog exhibition in Norway in 1877. The AKC breed name "Norwegian Elkhound" is a mistranslation from its original Norwegian name , meaning "Norwegian moose dog". In Norwegian "elg" means "moose" and "hund" means "dog," as it does in many other Germanic languages. It is Spitz breed, not a "hound" dog. The breed's object in the hunt is to independently track down and hold the moose at bay—jumping in and out toward the moose, distracting its attention, while signaling to the hunters by barking very loudly—until the hunter who follows the sound can arrive to shoot it. The dog will only bark while the moose is stationary, but it can also slowly drive the ...
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Miniature Schnauzer
The Miniature Schnauzer is a breed of small dog of the Schnauzer type that originated in Germany in the mid-to-late 19th century. Miniature Schnauzers may have been developed from the smallest specimens of the Standard Schnauzer, or crosses between the standard and one or more smaller breeds such as the Affenpinscher, Miniature Pinscher, and Poodles, as farmers bred a small dog that was an efficient ratting dog. They are described as "spunky" but aloof dogs, with good guarding tendencies without some guard dogs' predisposition to bite. Miniature Schnauzers are recognized in four colors internationally: solid black, black and silver, salt and pepper, and white. It is the most popular Schnauzer breed, and remains one of the most popular worldwide, primarily for its temperament and relatively small size. As of 2020 it is the 19th most popular breed in the U.S. History The earliest records surrounding the development of the Standard Schnauzer in Germany come from the late 19th cent ...
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Calcium
Calcium is a chemical element with the symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive metal that forms a dark oxide-nitride layer when exposed to air. Its physical and chemical properties are most similar to its heavier homologues strontium and barium. It is the fifth most abundant element in Earth's crust, and the third most abundant metal, after iron and aluminium. The most common calcium compound on Earth is calcium carbonate, found in limestone and the fossilised remnants of early sea life; gypsum, anhydrite, fluorite, and apatite are also sources of calcium. The name derives from Latin ''calx'' "lime", which was obtained from heating limestone. Some calcium compounds were known to the ancients, though their chemistry was unknown until the seventeenth century. Pure calcium was isolated in 1808 via electrolysis of its oxide by Humphry Davy, who named the element. Calcium compounds are widely used in many industries: in foods and pharma ...
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Shih Tzu
The Shih Tzu (, ; literally " Hsi Shih dog") is a toy dog breed originating from Tibet and was bred from the Pekingese and the Lhasa Apso. Shih Tzus are known for their short snouts and large round eyes, as well as their long coat, floppy ears, and short and stout posture. They are well known for their playful personality and calm and friendly temperament. They are able to adapt well in different situations. Due to their highly independent nature, they are not considered the most obedient breed. Description The Shih Tzu is a sturdy dog with a small muzzle and normally has large dark brown eyes. The Chinese have described their head shapes as "owl head" and "lion head", and their mouth as "frog mouth". They have a soft and long double coat that will tangle and mat easily if not brushed at least every 2 or 3 days. A Shih Tzu should stand no more than 26.7 cm (10") at the withers and with an ideal weight of 4.0 to 7.5 kg (9 to 17 lb). Floppy ears are covered with ...
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Lhasa Apso
The Lhasa Apso ( ) is a non-sporting dog breed originating in Tibet. It has traditionally been used as an interior sentinel. Etymology Lhasa is the capital city of Tibet, and ''apso'' is a word from the Tibetan language. There is some debate over the exact origin of the name; some claim that the word "apso" is an anglicized form of the Tibetan word for goatee ("ag-tshom", ཨག་ཚོམ་) or perhaps "ra-pho" (ར་ཕོ་) meaning "billy goat". It may also be a compound noun meaning "bark-guard" (lit. "ap" ½¨à½” to bark, and "so" ½¦à½¼à¼‹ to guard). History The Lhasa Apso originated in Tibet. In the early twentieth century some Tibetan dogs were brought to the United Kingdom by military men returning from the Indian subcontinent. These were of mixed types, similar either to what would become the Lhasa Apso or to what would become the Tibetan Terrier; they were collectively known as "Lhasa Terrier". The original American pair of Lhasas was a gift from Thubten ...
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Leiomyoma
A leiomyoma, also known as a fibroid, is a benign smooth muscle tumor that very rarely becomes cancer (0.1%). They can occur in any organ, but the most common forms occur in the uterus, small bowel, and the esophagus. Polycythemia may occur due to increased erythropoietin production as part of a paraneoplastic syndrome. The word is from '' leio-'' + '' myo-'' + '' -oma'', "smooth-muscle tumor". The plural form can be either the English leiomyomas or the classical leiomyomata. Uterus Uterine fibroids are leiomyomata of the uterine smooth muscle. As other leiomyomata, they are benign, but may lead to excessive menstrual bleeding (menorrhagia), often cause anemia and may lead to infertility. A rare form of these tumors is uterine lipoleiomyoma—benign tumors consisting of a mixture of adipocytes and smooth muscle cells. Uterine lipoleiomyomata have been observed together with ovarian and other pathologies and some of them may develop into liposarcoma. These tumors are monoclona ...
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Uterus
The uterus (from Latin ''uterus'', plural ''uteri'') or womb () is the organ in the reproductive system of most female mammals, including humans that accommodates the embryonic and fetal development of one or more embryos until birth. The uterus is a hormone-responsive sex organ that contains glands in its lining that secrete uterine milk for embryonic nourishment. In the human, the lower end of the uterus, is a narrow part known as the isthmus that connects to the cervix, leading to the vagina. The upper end, the body of the uterus, is connected to the fallopian tubes, at the uterine horns, and the rounded part above the openings to the fallopian tubes is the fundus. The connection of the uterine cavity with a fallopian tube is called the uterotubal junction. The fertilized egg is carried to the uterus along the fallopian tube. It will have divided on its journey to form a blastocyst that will implant itself into the lining of the uterus – the endometrium, where it will ...
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Cystadenocarcinoma
Cystadenocarcinoma is a malignant form of a cystadenoma and is a cancer derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. Similar tumor histology has also been reported in the pancreas, although it is a considerably rarer entity representing 1–1.5% of all Pancreatic cancer. A cystadenocarcinoma contains complex multi-loculated cyst but with exuberant solid areas in places. It usually presents with omental metastases which cause fluid accumulation in the peritoneal cavity (ascites). Cystadenocarcinomas can be classified into serous cystadenocarcinomas and mucinous cystadenomcarcinomas. Serous cystadenocarcinomas Among the ovarian tumours, serous tumours are most common, having a variegated appearance. ...
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