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Familial Hypercholesterolemia
Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels, specifically very high levels of low-density lipoprotein (LDL cholesterol), in the blood and early cardiovascular disease. The most common mutations diminish the number of functional LDL receptors in the liver. Since the underlying body biochemistry is slightly different in individuals with FH, their high cholesterol levels are less responsive to the kinds of cholesterol control methods which are usually more effective in people without FH (such as dietary modification and statin tablets). Nevertheless, treatment (including higher statin doses) is usually effective. FH is classified as a type 2 familial dyslipidemia. There are five types of familial dyslipidemia (not including subtypes), and each are classified from both the altered lipid profile and by the genetic abnormality. For example, high LDL (often due to LDL receptor defect) is type 2. Others include defects in chylomicron ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
McDonnell FH Phantom
The McDonnell FH Phantom is a twinjet fighter aircraft designed and first flown during World War II for the United States Navy. The Phantom was the first purely jet-powered aircraft to land on an American aircraft carrier and the first jet deployed by the United States Marine Corps. Although only 62 FH-1s had been built by the end of the war it helped prove the viability of carrier-based jet fighters. As McDonnell's first successful fighter, it led to the development of the follow-on F2H Banshee, which was one of the two most important naval jet fighters of the Korean War; combined, the two established McDonnell as an important supplier of navy aircraft. McDonnell chose to bring the name back with the Mach 2–class McDonnell Douglas F-4 Phantom II, the most versatile and widely used western combat aircraft of the Vietnam War era. The FH Phantom was originally designated the FD Phantom, but this was changed as the aircraft entered production. Design and development In early 19 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fachhochschule
A ''Fachhochschule'' (; plural ''Fachhochschulen''), abbreviated FH, is a university of applied sciences (UAS), in other words a German tertiary education institution that provides professional education in many applied sciences and applied arts, such as engineering, technology, business, architecture, design, and industrial design. ''Fachhochschulen'' were first founded in Germany and were later adopted in Austria, Liechtenstein, Switzerland, Cyprus, and Greece. An increasing number of ''Fachhochschulen'' are abbreviated as ''Hochschule'', the generic term in Germany for institutions awarding academic degrees in higher education, or expanded as ''Hochschule für angewandte Wissenschaften (HAW)'', the German translation of "universities of applied sciences", which are primarily designed with a focus on teaching professional skills. Swiss law calls ''Fachhochschulen'' and universities "separate but equal". Due to the Bologna process, universities and ''Fachhochschulen'' award l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fumarase
Fumarase (or fumarate hydratase) is an enzyme () that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs cycle and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety. This enzyme participates in 2 metabolic pathways: citric acid cycle and reductive citric acid cycle (CO2 fixation), and is also important in renal cell carcinoma. Mutations in this gene have been associated with the development of leiomyomas in the skin and uterus in combination with renal cell carcinoma ( HLRCC syndrome). Nomenclature This enzyme belongs to the family of lyases, specifical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Factor H
Factor H is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble glycoprotein that circulates in human plasma (at typical concentrations of 200–300 micrograms per milliliter). Its principal function is to regulate the alternative pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3-convertase, C3bBb. Factor H exerts its protective action on self cells and self surfaces but not on the surfaces of bacteria or viruses. This is thought to be the result of Factor H having the ability to adopt conformations with lower or higher activities as a cofactor for C3 cleavage or decay accelerat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fimleikafélag Hafnarfjarðar
Fimleikafélag Hafnarfjarðar ( en, Hafnarfjörður Gymnastics Club), commonly referred to as FH, is an Icelandic multi-sports club based in Hafnarfjörður. The club competes in football, handball, athletics, and fencing. It was founded in 1929 as a gymnastics club but soon started a handball department which became its flagship for several decades. Its men's football team has been a dominant power since the early 2000s. Football Men's football FH's men's football team has been a dominant power in Icelandic football since the early 2000s, winning several national championships. Women's football FH's women's football team won the first edition of the national championship in 1972. After losing the title to Ármann in 1973, FH won three successive titles in 1974, 1975 and 1976. The club was promoted from the second-tier 1. deild in 2015, and finished sixth in the 2016 Úrvalsdeild. Handball Men's handball Titles * Icelandic champions ** Winners (16): 1956, 1957, 1959, 196 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Danish Trade Union Confederation
The Danish Trade Union Confederation ( da, Fagbevægelsens Hovedorganisation, FH) is the largest national trade union centre in Denmark. On formation in 2019, it had 79 affiliated unions, with a total of 1.4 million members. History The confederation was founded on 1 January 2019, when the Danish Confederation of Trade Unions (LO) merged with the Confederation of Professionals in Denmark (FTF). LO consisted of 18 unions, with a total of one million members, most of whom worked in the private sector, while FTF consisted of 70 professional organisations, with a total of just under 500,000 members, most of whom worked in the public sector. LO and FTF began discussing a possible merger in 2015. Some affiliates were dubious about the proposition. The FTF's Finance Federation opposed the merger, while LO's largest affiliate, the United Federation of Danish Workers (3F), only decided to support it early in March 2018. One week after 3F's decision, the FTF and LO voted on the propo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Federation Of The Swiss Watch Industry FH
The Federation of the Swiss Watch Industry (FH) is the Swiss watch industry's leading trade association, headquartered in Bienne, Switzerland. The Federation is a private, professional and non-profit association. The Federation of the Swiss Watch Industry was established on 19 November 1982 as the result of the merger of the Swiss Federation of Watch Manufacturers’ Associations (founded in 1876) and the Swiss Chamber of Watchmaking (founded in 1924). It currently gathers more than 500 members representing more than 90% of all Swiss watch manufacturers (watches, clocks, movements, components, etc.). History On 14 May 1876, the Intercantonal Association of Jura Industries was founded in Switzerland. In 1900, it became the ''Swiss Chamber of Watchmaking and Allied Industries'', extending the focus to include jewellery, gold & silver work, and music boxes. The ''Swiss Federation of Clock and Watch Manufacturers’ Associations (FH)'' was established in 1924 by delegates from Be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Falcon Heavy
Falcon Heavy is a partially reusable heavy-lift launch vehicle that is produced by SpaceX, an American aerospace manufacturer. The rocket consists of two strap-on boosters made from Falcon 9 first stages, a center core also made from a Falcon 9 first stage, and a second stage on top. Falcon Heavy has the second highest payload capacity of any currently operational launch vehicle behind NASA's Space Launch System and the fourth-highest capacity of any rocket to reach orbit, trailing the Saturn V, Energia and Space Launch System. SpaceX conducted Falcon Heavy's maiden launch on 6 February 2018, at 20:45 UTC. The rocket carried Elon Musk's Tesla Roadster belonging to SpaceX founder Elon Musk, with a dummy dubbed "Starman" in the driver's seat, as a dummy payload. The second Falcon Heavy launch occurred on 11 April 2019, and all three booster rockets successfully returned to Earth. The third Falcon Heavy launch successfully occurred on 25 June 2019. Since then, Falcon Heavy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Futura International Airways
Futura International Airways was an airline with its head office in the ''Zona Facturación'' on the property of Palma de Mallorca Airport in Palma de Mallorca, Spain. It operated scheduled services and charter flights for tour operators and other airlines, in Europe, as well as wet lease and ad hoc charters. Its main base was Palma de Mallorca Airport. After failing to re-finance itself the company ceased trading on the 8 September 2008, leaving many passengers stranded in and around Spain. There was also an intrastate airline operating in California in the U.S. in 1962 flying as Futura Airlines with Lockheed Constellation propliners serving Los Angeles, Oakland, Sacramento, Fresno, Bakersfield and Lake Tahoe. History The airline was established in 1989 by Aer Lingus, Belton Air and Banco Santander, starting operations on 17 February 1990 with a flight from Palma de Mallorca to Manchester. During the 1990s, the airline expanded to cover the whole of Europe, includ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Faculty Of Humanities (The Hong Kong Polytechnic University)
The Hong Kong Polytechnic University (PolyU) is a public research university located in Hung Hom, Hong Kong near Hung Hom station. The University is one of the eight government-funded degree-granting tertiary institutions in Hong Kong. Founded in 1937 as the first Government Trade School, it is the first institution to provide technical education in Hong Kong. In 1994, the Legislative Council of Hong Kong passed a bill which granted the former Hong Kong Polytechnic official university status. PolyU consists of 8 faculties and schools, offering programmes covering applied science, business, construction, environment, engineering, social science, health, humanities, design, hotel and tourism management. The university offers over 160 taught programmes for more than 25,800 students every year. It is the largest public tertiary institution in terms of number of students. As of 2022-23, PolyU ranks 79th worldwide by THE, 65th internationally by QS, 100th in US News and 15 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ferrihydrite
Ferrihydrite (Fh) is a widespread hydrous ferric oxyhydroxide mineral at the Earth's surface, and a likely constituent in extraterrestrial materials. It forms in several types of environments, from freshwater to marine systems, aquifers to hydrothermal hot springs and scales, soils, and areas affected by mining. It can be precipitated directly from oxygenated iron-rich aqueous solutions, or by bacteria either as a result of a metabolic activity or passive sorption of dissolved iron followed by nucleation reactions. Ferrihydrite also occurs in the core of the ferritin protein from many living organisms, for the purpose of intra-cellular iron storage. Structure Ferrihydrite only exists as a fine grained and highly defective nanomaterial. The powder X-ray diffraction pattern of Fh contains two scattering bands in its most disordered state, and a maximum of six strong lines in its most crystalline state. The principal difference between these two diffraction end-members, commonly na ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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