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Froin's Syndrome
Froin's syndrome – coexistence of xanthochromia, high protein level and marked coagulation of cerebrospinal fluid (CSF). It is caused by meningeal irritation (e.g. during spinal meningitis) and CSF flow blockage by tumour mass or abscess. Stagnation of the CSF within the thecal sac facilitates exudation from the tumour itself and activation of coagulation factors. A clinical test formerly used for evaluation of spinal stenosis is Queckenstedt's maneuver. Nowadays, a magnetic resonance imaging is used for identification of CSF flow obstruction. It often shows the prolongation of T1 and T2 signal in CSF caudal Caudal may refer to: Anatomy * Caudal (anatomical term) (from Latin ''cauda''; tail), used to describe how close something is to the trailing end of an organism * Caudal artery, the portion of the dorsal aorta of a vertebrate that passes into the ... to a level of block. This phenomenon is named after Georges Froin (1874–1932), a French physician who first described ...
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Ependymoma
An ependymoma is a tumor that arises from the ependyma, a tissue of the central nervous system. Usually, in pediatric cases the location is intracranial, while in adults it is spinal. The common location of intracranial ependymomas is the fourth ventricle. Rarely, ependymomas can occur in the pelvic cavity. Syringomyelia can be caused by an ependymoma. Ependymomas are also seen with neurofibromatosis type II. Signs and symptoms Source: * severe headache * visual loss (due to papilledema) * vomiting * bilateral Babinski sign * drowsiness (after several hours of the above symptoms) * gait change (rotation of feet when walking) * impaction/constipation * back flexibility Morphology Ependymomas are composed of cells with regular, round to oval nuclei. There is a variably dense fibrillary background. Tumor cells may form gland-like round or elongated structures that resemble the embryologic ependymal canal, with long, delicate processes extending into the lumen; more frequently pre ...
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Coagulation Factor
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechanism of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. Coagulation begins almost instantly after an injury to the endothelium lining a blood vessel. Exposure of blood to the subendothelial space initiates two processes: changes in platelets, and the exposure of subendothelial tissue factor to plasma factor VII, which ultimately leads to cross-linked fibrin formation. Platelets immediately form a plug at the site of injury; this is called ''primary hemostasis. Secondary hemostasis'' occurs simultaneously: additional coagulation (clotting) factors beyond factor VII ( listed below) respond in a cascade to form fibrin strands, which strengthen the platelet plug. Disorders of ...
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Georges Froin
Georges may refer to: Places *Georges River, New South Wales, Australia *Georges Quay (Dublin) *Georges Township, Fayette County, Pennsylvania Other uses *Georges (name) * ''Georges'' (novel), a novel by Alexandre Dumas * "Georges" (song), a 1977 song originally recorded by Pat Simon and covered by Sylvie Vartan *Georges (store), a department store in Melbourne, Australia from 1880 to 1995 * Georges (''Green Card'' character) People with the surname *Eugenia Georges, American anthropologist *Karl Ernst Georges (1806–1895), German classical philologist and lexicographer, known for his edition of Latin-German dictionaries. See also *École secondaire Georges-P.-Vanier, a high school in Hamilton, Ontario, Canada *École secondaire Georges-Vanier in Laval, Quebec, Canada * French cruiser ''Georges Leygues'', commissioned in 1937 * French frigate ''Georges Leygues'' (D640), commissioned in 1979 *George (other) *Georges Creek (other) *Georges Creek Coal and Iron Com ...
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Caudal (anatomical Term)
Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek language, Greek roots, describe something in its standard anatomical position. This position provides a definition of what is at the front ("anterior"), behind ("posterior") and so on. As part of defining and describing terms, the body is described through the use of anatomical planes and anatomical axis, anatomical axes. The meaning of terms that are used can change depending on whether an organism is bipedal or quadrupedal. Additionally, for some animals such as invertebrates, some terms may not have any meaning at all; for example, an animal that is radially symmetrical will have no anterior surface, but can still have a description that a part is close to the middle ("proximal") or further from the middle ("distal"). International organisations have determined vocabularies that are often used as standard vocabular ...
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Spin–spin Relaxation
In physics, the spin–spin relaxation is the mechanism by which , the transverse component of the magnetization vector, exponentially decays towards its equilibrium value in nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI). It is characterized by the spin–spin relaxation time, known as 2, a time constant characterizing the signal decay. It is named in contrast to 1, the spin–lattice relaxation time. It is the time it takes for the magnetic resonance signal to irreversibly decay to 37% (1/ e) of its initial value after its generation by tipping the longitudinal magnetization towards the magnetic transverse plane. Hence the relation :M_(t) = M_(0) e^ \,. 2 relaxation generally proceeds more rapidly than 1 recovery, and different samples and different biological tissues have different 2. For example, fluids have the longest 2 (on the order of seconds for protons), and water based tissues are in the 40–200  ms range, while fat based tissues are in ...
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Spin–lattice Relaxation
During nuclear magnetic resonance observations, spin–lattice relaxation is the mechanism by which the longitudinal component of the total nuclear magnetic moment vector (parallel to the constant magnetic field) exponentially relaxes from a higher energy, non-equilibrium state to thermodynamic equilibrium with its surroundings (the "lattice"). It is characterized by the spin–lattice relaxation time, a time constant known as ''T1''. There is a different parameter, ''T2'', the spin-spin relaxation time, which concerns the exponential relaxation of the transverse component of the nuclear magnetization vector ( to the external magnetic field). Measuring the variation of ''T1'' and ''T2'' in different materials is the basis for some magnetic resonance imaging techniques. Nuclear physics ''T1'' relaxation or longitudinal relaxation curve ''T1'' characterizes the rate at which the longitudinal ''Mz'' component of the magnetization vector recovers exponentially towards its thermodynam ...
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Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from CT and PET scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. MRI is widely used in hospitals and clinics for medical diagnosis, staging and follow-up of disease. Compared to CT, MRI provides better contrast in images of soft-tissues, e.g. in the brain or abdomen. However, it may be perceived as less comfortable by patients, due to the usually longer and louder measurements with the subject in a long, confining tube, though "Open" MRI designs mostly relieve this. Additionally, implants and oth ...
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Queckenstedt's Maneuver
Queckenstedt's maneuver is a clinical test, formerly used for diagnosing spinal stenosis. The test is performed by placing the patient in the lateral decubitus position, thereafter the clinician performs a lumbar puncture. The opening pressure is measured. Then, the clinician's assistant compresses both jugular veins (if increased intracranial pressure is not suspected then one may exert pressure on both external jugular veins but usually pressure is first exerted on the abdomen, this pressure causes an engorgement of spinal veins and in turn rapidly increases cerebrospinal fluid pressure), which leads to a rise in the intracranial pressure. Given normal anatomy, the intracranial pressure will be reflected as a rapidly rising pressure measured from the lumbar needle, within 10–12 seconds. If there is a stenosis in the spine, there will be a damped, delayed response in the lumbar pressure, thus a positive Queckenstedt's maneuver. Nowadays this test has been made mostly superflu ...
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Spinal Stenosis
Spinal stenosis is an abnormal narrowing of the spinal canal or neural foramen that results in pressure on the spinal cord or nerve roots. Symptoms may include pain, numbness, or weakness in the arms or legs. Symptoms are typically gradual in onset and improve with leaning forward. Severe symptoms may include loss of bladder control, loss of bowel control, or sexual dysfunction. Causes may include osteoarthritis, rheumatoid arthritis, spinal tumors, trauma, Paget's disease of the bone, scoliosis, spondylolisthesis, and the genetic condition achondroplasia. It can be classified by the part of the spine affected into cervical, thoracic, and lumbar stenosis. Lumbar stenosis is the most common, followed by cervical stenosis. Diagnosis is generally based on symptoms and medical imaging. Treatment may involve medications, bracing, or surgery. Medications may include NSAIDs, acetaminophen, or steroid injections. Stretching and strengthening exercises may also be useful. Limiting ...
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Exudation
An exudate is a fluid emitted by an organism through pores or a wound, a process known as exuding or exudation. ''Exudate'' is derived from ''exude'' 'to ooze' from Latin ''exsūdāre'' 'to (ooze out) sweat' (''ex-'' 'out' and ''sūdāre'' 'to sweat'). Medicine An exudate is any fluid that filters from the circulatory system into lesions or areas of inflammation. It can be a pus-like or clear fluid. When an injury occurs, leaving skin exposed, it leaks out of the blood vessels and into nearby tissues. The fluid is composed of serum, fibrin, and leukocytes. Exudate may ooze from cuts or from areas of infection or inflammation. Types * Purulent or suppurative exudate consists of plasma with both active and dead neutrophils, fibrinogen, and necrotic parenchymal cells. This kind of exudate is consistent with more severe infections, and is commonly referred to as pus. * Fibrinous exudate is composed mainly of fibrinogen and fibrin. It is characteristic of rheumatic carditis, bu ...
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Spinal Cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the spinal cord, which contains cerebrospinal fluid. The brain and spinal cord together make up the central nervous system (CNS). In humans, the spinal cord begins at the occipital bone, passing through the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it ends. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diameter of the spinal cord ranges from in the cervical and lumbar regions to in the thoracic area. The spinal cord functions primarily in the transmission of nerve signals from the motor cortex to the body, ...
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