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Fondation Mérieux
The Fondation Mérieux is an independent family foundation recognized for public utility created by Charles Mérieux. Its mission is to contribute to global health by strengthening local capacities in developing countries to reduce the impact of infectious diseases on vulnerable populations. History The FM was created in 1967 by Doctor Charles Mérieux, in homage to his father Marcel Mérieux, pupil of Louis Pasteur and founder of the Institut Mérieux in 1897. It was recognized in French law as "for public utility" in 1976. The foundation is present in 18 countries such as Mali, Cambodia, Laos and Haiti. and builds its projects with the health authorities and local partners. In October 2004, the FM was the beneficiary of a Franco-Chinese agreement that led to the creation of the Institut Pasteur de Shanghai and the donation of four truck-trailer BSL-3 laboratories, supplied by Labover. In 2012, the FM continued its partnership with the Chinese Academy of Medical Science ...
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Charles Mérieux
Charles is a masculine given name predominantly found in English and French speaking countries. It is from the French form ''Charles'' of the Proto-Germanic name (in runic alphabet) or ''*karilaz'' (in Latin alphabet), whose meaning was "free man". The Old English descendant of this word was '' Ċearl'' or ''Ċeorl'', as the name of King Cearl of Mercia, that disappeared after the Norman conquest of England. The name was notably borne by Charlemagne (Charles the Great), and was at the time Latinized as ''Karolus'' (as in '' Vita Karoli Magni''), later also as '' Carolus''. Some Germanic languages, for example Dutch and German, have retained the word in two separate senses. In the particular case of Dutch, ''Karel'' refers to the given name, whereas the noun ''kerel'' means "a bloke, fellow, man". Etymology The name's etymology is a Common Germanic noun ''*karilaz'' meaning "free man", which survives in English as churl (< Old English ''ċeorl''), which developed it ...
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Beijing
} Beijing ( ; ; ), alternatively romanized as Peking ( ), is the capital of the People's Republic of China. It is the center of power and development of the country. Beijing is the world's most populous national capital city, with over 21 million residents. It has an administrative area of , the third in the country after Guangzhou and Shanghai. It is located in Northern China, and is governed as a municipality under the direct administration of the State Council with 16 urban, suburban, and rural districts.Figures based on 2006 statistics published in 2007 National Statistical Yearbook of China and available online at archive. Retrieved 21 April 2009. Beijing is mostly surrounded by Hebei Province with the exception of neighboring Tianjin to the southeast; together, the three divisions form the Jingjinji megalopolis and the national capital region of China. Beijing is a global city and one of the world's leading centres for culture, diplomacy, politics, finance, busi ...
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Mérieux Family
The Mérieux family is an entrepreneurial dynasty from Lyon, France, owners of the Institut Mérieux holding, founders of companies such as Sanofi Pasteur, bioMérieux (in vitro diagnostics) and Mérial (veterinary activity), but also of the foundations '' Fondation Marcel-Mérieux'' and ''Fondation Christophe et Rodolphe Mérieux'', of the Jean Mérieux P4 laboratory and of humanitarian organisation Bioforce. Genealogy *Marcel Mérieux (1870–1937), ESCIL student in 1891, former assistant to Pasteur, founder in 1897 of Mérieux Biological Institute in Lyon (origins of the ''Institut Mérieux'' holding) in 1897 (now part of Sanofi Pasteur) **Jean Mérieux, his elder son. Physician, died at 26 of tuberculosis-related meningitis contracted in the family laboratory. **Charles Mérieux (1907–2001), physician and entrepreneur. Founder of Fondation Marcel-Mérieux, humanitarian organisation Bioforce and '' P4'' laboratory Jean Merieux. ***Jean Mérieux, died in a car accident in ...
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CRISPR
CRISPR () (an acronym for clustered regularly interspaced short palindromic repeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. These sequences are derived from DNA fragments of bacteriophages that had previously infected the prokaryote. They are used to detect and destroy DNA from similar bacteriophages during subsequent infections. Hence these sequences play a key role in the antiviral (i.e. anti-phage) defense system of prokaryotes and provide a form of acquired immunity. CRISPR is found in approximately 50% of sequenced bacterial genomes and nearly 90% of sequenced archaea. Cas9 (or "CRISPR-associated protein 9") is an enzyme that uses CRISPR sequences as a guide to recognize and cleave specific strands of DNA that are complementary to the CRISPR sequence. Cas9 enzymes together with CRISPR sequences form the basis of a technology known as CRISPR-Cas9 that can be used to edit genes within organisms. This editing ...
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COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, Anosmia, loss of smell, and Ageusia, loss of taste. Symptoms may begin one to fourteen days incubation period, after exposure to the virus. At least a third of people who are infected Asymptomatic, do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, Hypoxia (medical), hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure ...
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Genotype A21
The genotype of an organism is its complete set of genetic material. Genotype can also be used to refer to the alleles or variants an individual carries in a particular gene or genetic location. The number of alleles an individual can have in a specific gene depends on the number of copies of each chromosome found in that species, also referred to as ploidy. In diploid species like humans, two full sets of chromosomes are present, meaning each individual has two alleles for any given gene. If both alleles are the same, the genotype is referred to as homozygous. If the alleles are different, the genotype is referred to as heterozygous. Genotype contributes to phenotype, the observable traits and characteristics in an individual or organism. The degree to which genotype affects phenotype depends on the trait. For example, the petal color in a pea plant is exclusively determined by genotype. The petals can be purple or white depending on the alleles present in the pea plant. Ho ...
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Human Rhinovirus
The rhinovirus (from the grc, ῥίς, rhis "nose", , romanized: "of the nose", and the la, vīrus) is the most common viral infectious agent in humans and is the predominant cause of the common cold. Rhinovirus infection proliferates in temperatures of 33–35 °C (91–95 °F), the temperatures found in the nose. Rhinoviruses belong to the genus ''Enterovirus'' in the family ''Picornaviridae''. The three species of rhinovirus (A, B, and C) include around 160 recognized types (called serotypes) of human rhinovirus that differ according to their surface antigens. They are lytic in nature and are among the smallest viruses, with diameters of about 30 nanometers. By comparison, other viruses, such as smallpox and vaccinia, are around ten times larger at about 300 nanometers, while flu viruses are around 80–120 nm. History In 1953, when a cluster of nurses developed a mild respiratory illness, Winston Price, from the Johns Hopkins University, took nasal pass ...
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The Washington Post
''The Washington Post'' (also known as the ''Post'' and, informally, ''WaPo'') is an American daily newspaper published in Washington, D.C. It is the most widely circulated newspaper within the Washington metropolitan area and has a large national audience. Daily broadsheet editions are printed for D.C., Maryland, and Virginia. The ''Post'' was founded in 1877. In its early years, it went through several owners and struggled both financially and editorially. Financier Eugene Meyer purchased it out of bankruptcy in 1933 and revived its health and reputation, work continued by his successors Katharine and Phil Graham (Meyer's daughter and son-in-law), who bought out several rival publications. The ''Post'' 1971 printing of the Pentagon Papers helped spur opposition to the Vietnam War. Subsequently, in the best-known episode in the newspaper's history, reporters Bob Woodward and Carl Bernstein led the American press's investigation into what became known as the Watergate scandal ...
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Wuhan Institute Of Virology
The Wuhan Institute of Virology, Chinese Academy of Sciences (WIV; ) is a research institute on virology administered by the Chinese Academy of Sciences (CAS), which reports to the State Council of the People's Republic of China. The institute is one of nine independent organisations in the Wuhan Branch of the CAS. Located in Jiangxia District, Wuhan, Hubei, it opened mainland China's first biosafety level 4 (BSL-4) laboratory. The institute has collaborated with the Galveston National Laboratory in the United States, the Centre International de Recherche en Infectiologie in France, and the National Microbiology Laboratory in Canada. The institute has been an active premier research center for the study of coronaviruses. History The WIV was founded in 1956 as the Wuhan Microbiology Laboratory under the Chinese Academy of Sciences (CAS). It was established by scientists Gao Shangyin, a graduate of Soochow University (Suzhou), and Chen Huagui. In 1961, it became the South China ...
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Centre International De Recherche En Infectiologie
The Centre International de Recherche en Infectiologie is an academic and research institute based in Lyon, France. __TOC__ Synopsis The CIRI is composed of 22 teams gathered behind one goal: the fight against infectious diseases (which is the second cause of death worldwide) by "promoting in-depth conceptual and technological advances through approaches that span from fundamental to clinical/applied research." The key areas of expertise of the CIRI teams are bacteriology, immunology and virology. The CIRI contains a Biosafety Level 4 laboratory. History The CIRI was created in 2013 by the Inserm, the CNRS, the ENS de Lyon and the Université Claude Bernard Lyon 1 in partnership with the Pasteur Institute, the Mérieux Foundation, the VetAgroSup and the Hospices Civils de Lyon. A BSL-4 laboratory at the Wuhan Institute of Virology The Wuhan Institute of Virology, Chinese Academy of Sciences (WIV; ) is a research institute on virology administered by the Chinese Academy ...
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