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Follicular Lymphoma
Follicular lymphoma (FL) is a cancer that involves certain types of white blood cells known as lymphocytes. The cancer originates from the uncontrolled division of specific types of B-cells known as centrocytes and centroblasts. These cells normally occupy the follicles (nodular swirls of various types of lymphocytes) in the germinal centers of lymphoid tissues such as lymph nodes. The cancerous cells in FL typically form follicular or follicle-like structures (see adjacent Figure) in the tissues they invade. These structures are usually the dominant histological feature of this cancer. There are several synonymous and obsolete terms for FL such as CB/CC lymphoma (centroblastic and centrocytic lymphoma), nodular lymphoma, Brill-Symmers Disease, and the subtype designation, follicular large-cell lymphoma. In the US and Europe, this disease is the second most common form of non-Hodgkin's lymphomas, exceeded only by diffuse large B-cell lymphoma. FL accounts for 10-20% of non-Hodgkin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FL Studio
FL Studio (previously known as FruityLoops before 2003) is a digital audio workstation (DAW) developed by the Belgian company Image-Line. FL Studio features a graphical user interface with a pattern-based music sequencer. The program is available in four different editions for Microsoft Windows and macOS. Image-Line offers lifetime free updates to the program after one-time purchases, which means customers receive all future updates of the software for free after their purchase. Image-Line also develops FL Studio Mobile for Android, iOS, macOS and Universal Windows Platform devices. FL Studio can also be used as either a virtual studio technology (VST) or Audio Unit (AU) instrument in other audio workstation programs and also functions as a ReWire client. Image-Line also offers its own VST and AU instruments and audio applications. FL Studio has been used by numerous highly visible hip hop and EDM producers, including Porter Robinson, Alan Walker, Madeon, Soulja Boy, Sou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Volvo FL
The Volvo FL is Volvo's smallest truck and is suitable for local and regional distribution operations, refuse collection, construction truck or small format tractor. The Volvo FL has been built since the summer of 1985 in a variety of different models of different weight ratings. The latest model has been sold since 2013. History Volvo had lost much of its global market share in the medium weight segment by the 1970s and thus felt compelled to develop an entire new range of trucks to regain competitiveness. First generation "FL" stands for "Forward Control" and "Low-level Cab". The FL6 and the larger FL7 and FL10 appeared in the summer of 1985. In 1986 the smaller FL4 also appeared, with a 4 litre TD41 turbodiesel engine. Beginning in 1995 some of the FL6 models were equipped with the D6A250 engine, which utilized a turbocharger as well as a supercharger. This allowed for an unusually high power-to-weight ratio and plentiful low-end torque. Volvo's larger D7A engine, as fitted to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flight Level
In aviation and aviation meteorology, a flight level (FL) is an aircraft's altitude at standard air pressure, expressed in hundreds of feet. The air pressure is computed assuming an International Standard Atmosphere pressure of 1013.25 hPa (29.92 inHg) at sea level, and therefore is not necessarily the same as the aircraft's actual altitude, either above sea level or above ground level. Background Flight levels are used to ensure safe vertical separation between aircraft, despite natural local variations in atmospheric air pressure. Historically, altitude has been measured using a pressure altimeter, which is essentially a calibrated barometer. An altimeter measures ambient air pressure, which decreases with increasing altitude following the barometric formula. It then calculates and displays the corresponding altitude. If different aircraft's altimeters were not calibrated consistently, then two aircraft could be flying at the same altitude even though their altimeter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
English Football League
The English Football League (EFL) is a league of professional football clubs from England and Wales. Founded in 1888 as the Football League, the league is the oldest such competition in the world. It was the top-level football league in England from its foundation until 1992, when the top 22 clubs split from it to form the Premier League. The EFL is divided into the Championship, League One and League Two, with 24 clubs in each division, 72 in total, with promotion and relegation between them; the top Championship clubs change places with the lowest-placed clubs in the Premier League, and the bottom clubs of League Two with the top clubs of the National League. Although primarily an English competition, several clubs from Wales – currently Cardiff City, Swansea City and Newport County – also take part. The Football League had a sponsor from the 1983–84 season, and thus was known by various names. For the 2016–17 season, the league rebranded itself as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Florida
Florida is a state located in the Southeastern region of the United States. Florida is bordered to the west by the Gulf of Mexico, to the northwest by Alabama, to the north by Georgia, to the east by the Bahamas and Atlantic Ocean, and to the south by the Straits of Florida and Cuba; it is the only state that borders both the Gulf of Mexico and the Atlantic Ocean. Spanning , Florida ranks 22nd in area among the 50 states, and with a population of over 21 million, it is the third-most populous. The state capital is Tallahassee, and the most populous city is Jacksonville. The Miami metropolitan area, with a population of almost 6.2 million, is the most populous urban area in Florida and the ninth-most populous in the United States; other urban conurbations with over one million people are Tampa Bay, Orlando, and Jacksonville. Various Native American groups have inhabited Florida for at least 14,000 years. In 1513, Spanish explorer Juan Ponce de León became the first k ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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FL Group
Stodir ( is, Stoðir, FL Group prior to 4 June 2008) is a majority family-owned investment company located in Reykjavík, Iceland. The company was founded on July 20, 1973, under the name Flugleiðir. It was formed as a holding company for Loftleiðir and Air Iceland. FL Group was best known for its subsidiary Icelandair Group, which was sold in October 2006. Icelandair, Loftleidir Icelandic and other companies of Icelandair Group have been leaders in the Icelandic flight and tourism industry for about 70 years. The company was placed into administration in September 2008 after Glitnir, its largest investment, was part- nationalised by the Icelandic government. The company, then named Stodir, was restructured in 2009 and all shares delivered to its creditors. Between 2009 and 2016, all assets were sold and all debt repaid. In 2017, new shareholders acquired the company and Stodir was repositioned as an active investment company. History Before 2005 change The company t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemotherapy Regimens
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via cytotoxicity. A fundamental philosophy of medical oncology, including combination chemotherapy, is that different drugs work through different mechanisms, and that the results of using multiple drugs will be synergistic to some extent. Because they have different dose-limiting adverse effects, they can be given together at full doses in chemotherapy regimens. The first successful combination chemotherapy was MOPP, introduced in 1963 for lymphomas. The term " induction regimen" refers to a chemotherapy regimen used for the initial treatment of a disease. A " maintenance regimen" refers to the ongoing use of chemotherapy to reduce the chances of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FLT3LG
Fms-related tyrosine kinase 3 ligand (FLT3LG) is a protein which in humans is encoded by the ''FLT3LG'' gene. Flt3 ligand (FL) is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor (SCF) and colony stimulating factor 1 ( CSF-1). In synergy with other growth factors, Flt3 ligand stimulates the proliferation and differentiation of various blood cell progenitors. For example, it is a major growth factor stimulating the growth of dendritic cells. FLT3L functions as a cytokine and growth factor that increases the number of immune cells (lymphocytes ( B cells and T cells)) by activating the hematopoietic progenitors. It acts by binding to and activating FLT3 (CD135) which is found on what (in mice) are called multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells. It also induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FL (programming Language)
FL (short for "Function Level") is a programming language created at the IBM Almaden Research Center by John Backus, John Williams, and Edward Wimmers in the 1980s and documented in a report from 1989. FL was designed as a successor of Backus' earlier FP language, providing specific support for what Backus termed function-level programming. FL is a dynamically typed strict functional programming language with throw and catch exception semantics much like in ML. Each function has an implicit history argument which is used for doing things like strictly functional input/output (I/O), but is also used for linking to C code. For doing optimization, there exists a type-system which is an extension of Hindley–Milner type inference. Uses PLaSM PLaSM (Programming Language of Solid Modeling) is an open source scripting languageA. Paoluzzi: Geometric Programming for Computer Aided Design, Wiley, 2003 for solid modeling, a discipline that constitutes the foundation of computer-aide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diamond Clarity
Diamond clarity is the quality of diamonds that relates to the existence and visual appearance of internal characteristics of a diamond called ''inclusions'', and surface defects, called ''blemishes''. Clarity is one of the four Cs of diamond grading, the others being carat, color, and cut. Inclusions are solids, liquids, or gases that were trapped in a mineral as it formed. They may be crystals of a foreign material or even another diamond crystal, or may have produced structural imperfections, such as tiny cracks that make a diamond appear whitish or cloudy. The number, size, color, relative location, orientation, and visibility of inclusions can all affect the relative clarity of a diamond. A clarity grade is assigned based on the overall appearance of the stone under ten times magnification, which is the standard magnification for loupes used in the gem world. Most inclusions present in gem-quality diamonds do not affect the diamonds' performance or structural integrity and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
