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F. Dean Toste
F. Dean Toste (born 1971 in Terceira, Azores, Portugal) is the Gerald E. K. Branch Distinguished Professor of Chemistry at the University of California, Berkeley and faculty scientist at the chemical sciences division of Lawrence Berkeley National Laboratory, Lawrence Berkeley National Lab. He is a prominent figure in the field of organic chemistry and is best known for his contributions to gold chemistry and asymmetric ion-pairing catalysis. Toste was elected a member of the National Academy of Sciences in 2020, and a member of the American Academy of Arts and Sciences in 2018. Education and training Toste attended the University of Toronto for his undergraduate and masters studies in the group of Ian Still. With Still, Toste developed several novel reactions of thiocyanates that were then applied towards the synthesis of the natural product Varacin. He earned his B.Sc. in 1993 and his M.Sc. in 1995. Toste attended graduate school at Stanford University, earning his PhD under t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Terceira
Terceira () is a volcanic island in the Azores archipelago, in the middle of the North Atlantic Ocean. It is one of the larger islands of the archipelago, with a population of 53,311 inhabitants in an area of approximately . It is the location of the Azores' oldest city, Angra do Heroísmo, the historical capital of the archipelago and UNESCO World Heritage Site; the seat of the judicial system (Supreme Court); and the main Air Force base, Base Aérea nº 4 at Lajes, with a United States Air Force detachment. The island has two main sea ports, one at Angra do Heroísmo and the other at Praia da Vitória, and a commercial airport integrated with the flight operations at Base Aérea nº 4. The Portuguese bullfight is popular on the island, coming in two variations: the traditional equestrian bullfight (in the ring) and the popular " touradas à corda" that occur in the streets. History In 1439, the first official discovery document appeared, attributing the discovery of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enantioselective Synthesis
Enantioselective synthesis, also called asymmetric synthesis, is a form of chemical synthesis. It is defined by IUPAC as "a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric (enantiomeric or diastereomeric) products in unequal amounts." Put more simply: it is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer. Enantiomers are stereoisomers that have opposite configurations at every chiral center. Diastereomers are stereoisomers that differ at one or more chiral centers. Enantioselective synthesis is a key process in modern chemistry and is particularly important in the field of pharmaceuticals, as the different enantiomers or diastereomers of a molecule often have different biological activity. Overview Many of the building blocks of biological systems such as sugars and amino acids are produced exclusively as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of American Chemical Society National Awards
The List of American Chemical Society national awards attempts to include national awards, medals and prized offered by the American Chemical Society (ACS). The ACS national awards program began in 1922 with the establishment of the Priestley Medal, the highest award offered by the ACS. As of 2016, the ACS offers a 64 national awards, medals and prizes based on scientific and professional contributions in chemistry. A :Awards of the American Chemical Society, category of ACS awards is available on Wikipedia. The complete list of current awards is: * ACS Award for Achievement in Research for the Teaching and Learning of Chemistry * ACS Award for Affordable Green Chemistry * ACS Award for Computers in Chemical and Pharmaceutical Research * ACS Award for Creative Advances in Environmental Science and Technology * ACS Award for Creative Invention * ACS Award for Creative Work in Fluorine Chemistry * ACS Award for Creative Work in Synthetic Organic Chemistry * ACS Award for Distinguish ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c) organization, 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 60 Scientific journal, scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society Of Chemistry
The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Royal Institute of Chemistry, the Faraday Society, and the Society for Analytical Chemistry with a new Royal Charter and the dual role of learned society and professional body. At its inception, the Society had a combined membership of 34,000 in the UK and a further 8,000 abroad. The headquarters of the Society are at Burlington House, Piccadilly, London. It also has offices in Thomas Graham House in Cambridge (named after Thomas Graham (chemist), Thomas Graham, the first president of the Chemical Society) where ''RSC Publishing'' is based. The Society has offices in the United States, on the campuses of The University of Pennsylvania and Drexel University, at the University City Science Center in Philadelphia, Pennsylvania, in both Beijing a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Royal Society Of Chemistry Medals And Awards
The Royal Society of Chemistry grants a number of medals and awards. All those named "prize" (except the Beilby Medal and Prize) are awarded with a £5,000 bursary. The Chemistry World Entrepreneur of the Year award has one of £4,000. As of 2014, these are: * Applied Catalysis Award * Applied Inorganic Chemistry Award * Apprentice of the Year Award * Bader Award * Geoffrey Barker Medal * Barrer Award * Sir Derek Barton Gold Medal * Beilby Medal and Prize * Ronald Belcher Award * Anne Bennett Memorial Award for Distinguished Service * Becquerel Medal * Bill Newton Award * Bioinorganic Chemistry Award * Bioorganic Chemistry Award * Materials for Industry - Derek Birchall Award * Joseph Black Award * Bourke Award * Robert Boyle Prize for Analytical Science * S F Boys-A Rahman Award * Catalysis in Organic Chemistry Award * Centenary Prize * Joseph Chatt Award * Chemical Dynamics Award * Chemistry of Transition Metals Award * Chemistry World Entrepreneur of the Year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Humboldt Research Award
The Humboldt Prize, the Humboldt-Forschungspreis in German, also known as the Humboldt Research Award, is an award given by the Alexander von Humboldt Foundation of Germany to internationally renowned scientists and scholars who work outside of Germany in recognition of their lifetime's research achievements. Recipients are "academics whose fundamental discoveries, new theories or insights have had a significant impact on their own discipline and who are expected to continue producing cutting-edge academic achievements in the future". The prize is currently valued at €60,000 with the possibility of further support during the prize winner's life. Up to one hundred such awards are granted each year. Nominations must be submitted by established academics in Germany. The award is named after the Prussian naturalist and explorer Alexander von Humboldt. Past winners Biology Günter Blobel, Serge Daan, Aaron M. Ellison, Eberhard Fetz, Daniel Gianola, Hendrikus Granzier, Dan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Janssen Pharmaceuticals
Janssen Pharmaceuticals is a pharmaceutical company headquartered in Beerse, Belgium, and wholly-owned by Johnson & Johnson. It was founded in 1953 by Paul Janssen. In 1961, Janssen Pharmaceuticals was purchased by New Jersey-based American corporation Johnson & Johnson, and became part of Johnson & Johnson Pharmaceutical Research and Development (J&J PRD), now renamed to Janssen Research and Development (JRD), which conducts research and development activities related to a wide range of human medical disorders, including mental illness, neurological disorders, anesthesia and analgesia, gastrointestinal disorders, fungal infection, HIV/AIDS, allergies and cancer. Janssen and Ortho-McNeil Pharmaceutical have been placed in the Ortho-McNeil-Janssen group within Johnson & Johnson Company. Subsidiaries * Actelion * Cilag AG * Janssen Biotech (formerly ''Centocor'') * Janssen Vaccines (formerly ''Crucell'') * Tibotec * Beijing Dabao Cosmetics Co., Ltd. History The early roots ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Olefin Metathesis
Olefin metathesis is an organic reaction that entails the redistribution of fragments of alkenes (olefins) by the scission and regeneration of carbon-carbon double bonds. Because of the relative simplicity of olefin metathesis, it often creates fewer undesired by-products and hazardous wastes than alternative organic reactions. For their elucidation of the reaction mechanism and their discovery of a variety of highly active catalysts, Yves Chauvin, Robert H. Grubbs, and Richard R. Schrock were collectively awarded the 2005 Nobel Prize in Chemistry. Catalysts The reaction requires metal catalysts. Most commercially important processes employ heterogeneous catalysts. The heterogeneous catalysts are often prepared by in-situ activation of a metal halides (MClx) using organoaluminium or organotin compounds, e.g. combining MClx–EtAlCl2. A typical catalyst support is alumina. Commercial catalysts are often based on molybdenum and ruthenium. Well-defined organometallic co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
California Institute Of Technology
The California Institute of Technology (branded as Caltech or CIT)The university itself only spells its short form as "Caltech"; the institution considers other spellings such a"Cal Tech" and "CalTech" incorrect. The institute is also occasionally referred to as "CIT", most notably in its alma mater, but this is uncommon. is a private research university in Pasadena, California. Caltech is ranked among the best and most selective academic institutions in the world, and with an enrollment of approximately 2400 students (acceptance rate of only 5.7%), it is one of the world's most selective universities. The university is known for its strength in science and engineering, and is among a small group of institutes of technology in the United States which is primarily devoted to the instruction of pure and applied sciences. The institution was founded as a preparatory and vocational school by Amos G. Throop in 1891 and began attracting influential scientists such as George Ellery H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calanolide A
Calanolide A is an experimental non-nucleoside reverse transcriptase inhibitor (NNRTI). This compound was extracted from the tree ''Calophyllum lanigerum,'' of variety ''austrocoriaceum,'' in Lundu, Malaysian state of Sarawak in 1992 by United States National Cancer Institute (NCI). Due to rarity of the raw materials and low yield of the active ingredient, total synthesis of the compound was devised in 1996. For the same reason, its sister compound (-)-Calanolide B (also known as Costatolide) have been touted as replacement. As a result of the discovery of Calanolide A, Sarawak Medichem pharmaceuticals company was established as a joint venture between US-based MediChem Research Inc and Craun Research Sdn Bhd, a company owned by the Sarawak state government. In 2006, Craun Research acquired Sarawak MediChem. In 2016, Craun Research announced the completion of Phase I clinical trials for Calanolide A. History In December 1986, Arnold Arboretum of the Harvard University in Massac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aflatoxin B1
Aflatoxin B1 is an aflatoxin produced by ''Aspergillus flavus'' and '' A. parasiticus''. It is a very potent carcinogen with a TD50 3.2 μg/kg/day in rats. This carcinogenic potency varies across species with some, such as rats and monkeys, seemingly much more susceptible than others. Aflatoxin B1 is a common contaminant in a variety of foods including peanuts, cottonseed meal, corn, and other grains; as well as animal feeds. Aflatoxin B1 is considered the most toxic aflatoxin and it is highly implicated in hepatocellular carcinoma (HCC) in humans. In animals, aflatoxin B1 has also been shown to be mutagenic, teratogenic, and to cause immunosuppression. Several sampling and analytical methods including thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), mass spectrometry, and enzyme-linked immunosorbent assay (ELISA), among others, have been used to test for aflatoxin B1 contamination in foods. According to the Food and Agriculture Organization (FAO), t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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