Exserohilum Turcicum
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Exserohilum Turcicum
''Setosphaeria turcica'' (anamorph ''Exserohilum turcicum''; formerly known as ''Helminthosporium turcicum'') is the causal agent of northern corn leaf blight in maize. It is a serious fungal disease prevalent in cooler climates and tropical highlands wherever corn is grown. It is characterized by large cigar shaped necrotic lesions that develop on the leaves due to the polyketide metabolite monocerin. Races Races of ''S. turcica'' are named for the maize R genes which are not effective against them. For example, the maize gene ''Ht1'' does not confer resistance against a Race 1 isolate, while genes ''Ht2'' and/or ''Ht3'' do. In contrast, genes ''Ht2'' and ''HtN'' do not confer resistance against a Race 2N isolate, while gene ''Ht1'' does. Isolates which do not overcome any known R gene are termed Race 0. Race 1, which overcomes the ''Ht1'' resistance gene, was originally discovered in Hawaii in 1973. By the time it was first noted in the continental United States, in Indian ...
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Fungus
A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''true f ...
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R Gene
Resistance genes (R-Genes) are genes in plant genomes that convey plant disease resistance against pathogens by producing R proteins. The main class of R-genes consist of a nucleotide binding domain (NB) and a leucine rich repeat (LRR) domain(s) and are often referred to as (NB-LRR) R-genes or NLRs. Generally, the NB domain binds either ATP/ADP or GTP/GDP. The LRR domain is often involved in protein-protein interactions as well as ligand binding. NB-LRR R-genes can be further subdivided into toll interleukin 1 receptor (TIR-NB-LRR) and coiled-coil (CC-NB-LRR). Resistance can be conveyed through a number of mechanisms including: * The R protein interacts directly with an Avr geneAvirulence gene product of a pathogen (see Gene-for-Gene relationship). * The R protein guards another protein that detects degradation by an Avr gene (see Guard Hypothesis). * The R protein may detect a Pathogen-Associated Molecular Pattern or PAMP (alternatively called MAMP for microbe-as ...
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Fungal Plant Pathogens And Diseases
A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''true f ...
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Linkage Disequilibrium
In population genetics, linkage disequilibrium (LD) is the non-random association of alleles at different loci in a given population. Loci are said to be in linkage disequilibrium when the frequency of association of their different alleles is higher or lower than what would be expected if the loci were independent and associated randomly. Linkage disequilibrium is influenced by many factors, including selection, the rate of genetic recombination, mutation rate, genetic drift, the system of mating, population structure, and genetic linkage. As a result, the pattern of linkage disequilibrium in a genome is a powerful signal of the population genetic processes that are structuring it. In spite of its name, linkage disequilibrium may exist between alleles at different loci without any genetic linkage between them and independently of whether or not allele frequencies are in equilibrium (not changing with time). Furthermore, linkage disequilibrium is sometimes referred to as gamet ...
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Mating Type
Mating types are the microorganism equivalent to sexes in multicellular lifeforms and are thought to be the ancestor to distinct Sex, sexes. They also occur in macro-organisms such as fungi. Definition Mating types are the microorganism equivalent to sex in higher organisms and occur in isogamy, isogamous and anisogamous species. Depending on the group, different mating types are often referred to by numbers, letters, or simply "+" and "−" instead of "male" and "female", which refer to "Sex, sexes" or differences in size between gametes. Syngamy can only take place between gametes carrying different mating types. Occurrence Reproduction by mating types is especially prevalent in Fungus, fungi. Filamentous ascomycetes usually have two mating types referred to as "MAT1-1" and "MAT1-2", following the yeast mating-type locus (MAT). Under standard nomenclature, MAT1-1 (which may informally be called MAT1) encodes for a regulatory protein with an alpha box motif, while MAT1-2 (informal ...
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Allele
An allele (, ; ; modern formation from Greek ἄλλος ''állos'', "other") is a variation of the same sequence of nucleotides at the same place on a long DNA molecule, as described in leading textbooks on genetics and evolution. ::"The chromosomal or genomic location of a gene or any other genetic element is called a locus (plural: loci) and alternative DNA sequences at a locus are called alleles." The simplest alleles are single nucleotide polymorphisms (SNP). but they can also be insertions and deletions of up to several thousand base pairs. Popular definitions of 'allele' typically refer only to different alleles within genes. For example, the ABO blood grouping is controlled by the ABO gene, which has six common alleles (variants). In population genetics, nearly every living human's phenotype for the ABO gene is some combination of just these six alleles. Most alleles observed result in little or no change in the function of the gene product it codes for. However, ...
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Ascomycete
Ascomycota is a phylum of the kingdom Fungi that, together with the Basidiomycota, forms the subkingdom Dikarya. Its members are commonly known as the sac fungi or ascomycetes. It is the largest phylum of Fungi, with over 64,000 species. The defining feature of this fungal group is the " ascus" (), a microscopic sexual structure in which nonmotile spores, called ascospores, are formed. However, some species of the Ascomycota are asexual, meaning that they do not have a sexual cycle and thus do not form asci or ascospores. Familiar examples of sac fungi include morels, truffles, brewers' and bakers' yeast, dead man's fingers, and cup fungi. The fungal symbionts in the majority of lichens (loosely termed "ascolichens") such as ''Cladonia'' belong to the Ascomycota. Ascomycota is a monophyletic group (it contains all descendants of one common ancestor). Previously placed in the Deuteromycota along with asexual species from other fungal taxa, asexual (or anamorphic) ascomycetes ...
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Mating-type Locus
The mating-type locus is a specialized region in the genomes of some yeast and other fungi, usually organized into heterochromatin and possessing unique histone methylation patterns. The genes in this region regulate the mating type of the organism and therefore determine key events in its biological life cycle, life cycle, such as whether it will reproduce sexual reproduction, sexually or asexual reproduction, asexually. In fission yeast such as ''Schizosaccharomyces pombe, S. pombe'', the formation and maintenance of the heterochromatin organization is regulated by RNA-induced transcriptional silencing, a form of RNA interference responsible for genomic maintenance in many organisms.Noma K, Sugiyama T, Cam H, Verdel A, Zofall M, Jia S, Moazed D, Grewal S (2004). "RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing". Nat Genet 36 (11): 1174-80. Mating type regions have also been well studied in budding yeast ''S. cerevisiae'' and ...
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Teleomorph
In mycology, the terms teleomorph, anamorph, and holomorph apply to portions of the life cycles of fungi in the phyla Ascomycota and Basidiomycota: *Teleomorph: the sexual reproductive stage (morph), typically a fruiting body. *Anamorph: an asexual reproductive stage (morph), often mold-like. When a single fungus produces multiple morphologically distinct anamorphs, these are called synanamorphs. *Holomorph: the whole fungus, including anamorphs and teleomorph. Dual naming of fungi Fungi are classified primarily based on the structures associated with sexual reproduction, which tend to be evolutionarily conserved. However, many fungi reproduce only asexually, and cannot easily be classified based on sexual characteristics; some produce both asexual and sexual states. These problematic species are often members of the Ascomycota, but a few of them belong to the Basidiomycota. Even among fungi that reproduce both sexually and asexually, often only one method of reproduction can be ...
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Heterothallic
Heterothallic species have sexes that reside in different individuals. The term is applied particularly to distinguish heterothallic fungi, which require two compatible partners to produce sexual spores, from homothallic ones, which are capable of sexual reproduction from a single organism. In heterothallic fungi, two different individuals contribute nuclei to form a zygote. Examples of heterothallism are included for ''Saccharomyces cerevisiae, Aspergillus fumigatus, Aspergillus flavus'', ''Penicillium marneffei'' and ''Neurospora crassa''. The heterothallic life cycle of ''N. crassa'' is given in some detail, since similar life cycles are present in other heterothallic fungi. Life cycle of ''Saccharomyces cerevisiae'' The yeast ''Saccharomyces cerevisiae'' is heterothallic. This means that each yeast cell is of a certain mating type and can only mate with a cell of the other mating type. During vegetative growth that ordinarily occurs when nutrients are abundant, ''S. cerev ...
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Monocerin
Monocerin is a dihydroisocoumarin and a polyketide metabolite that originates from various fungal species. It has been shown to display antifungal, plant pathogenic, and insecticidal characteristics. Monocerin has been isolated from '' Dreschlera monoceras'', '' D. ravenelii'', '' Exserohilum turcicum'', and '' Fusarium larvarum''. Biosynthesis Polyketide synthases (PKSs) of fungi are Type I PKSs. Monocerin has been confirmed by biosynthesis studies to have heptaketide origins. Monocerin PKS produces an intermediate with initially a high degree of reductive modification but ends with a classical β-polyketide moiety. Dihydroisocoumarin is the first PKS-free intermediate which would be formed from the reduced heptaketide whose assembly pathway is shown in figure 1. Ketosynthase, ketoreductase, dehydrates, enol reductases and cyclisases are shown as domains of the Monocerin PKS and methyl transferase is considered to be a tailoring enzyme. # Formation of an enolate ion on t ...
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Ascomycota
Ascomycota is a phylum of the kingdom Fungi that, together with the Basidiomycota, forms the subkingdom Dikarya. Its members are commonly known as the sac fungi or ascomycetes. It is the largest phylum of Fungi, with over 64,000 species. The defining feature of this fungal group is the " ascus" (), a microscopic sexual structure in which nonmotile spores, called ascospores, are formed. However, some species of the Ascomycota are asexual, meaning that they do not have a sexual cycle and thus do not form asci or ascospores. Familiar examples of sac fungi include morels, truffles, brewers' and bakers' yeast, dead man's fingers, and cup fungi. The fungal symbionts in the majority of lichens (loosely termed "ascolichens") such as ''Cladonia'' belong to the Ascomycota. Ascomycota is a monophyletic group (it contains all descendants of one common ancestor). Previously placed in the Deuteromycota along with asexual species from other fungal taxa, asexual (or anamorphic) ascomyce ...
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